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277
datasets available to search
ShareScore release 0.9.0
Dataset results
277 results for “novel proteins”
A novel human fetal lung-derived alveolar organoid model reveals mechanisms of surfactant protein C maturation relevant to interstitial lung disease
GEO Series GSE237359. Homo sapiens. 9 samples. Type: Expression profiling by high throughput sequencing; Third-party reanalysis.
Beyond the plasma membrane disruption: Novel antifungal mechanism of Neosartorya (Aspergillus) fischeri antifungal protein 2 in Candida albicans
GEO Series GSE290357. Candida albicans. 12 samples. Type: Expression profiling by high throughput sequencing.
Selectively targeting bromodomain and extraterminal proteins for degradation as a novel anti-glioblastoma strategy [RNA-seq]
GEO Series GSE99175. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
Thousands of novel unannotated proteins expand the MHC I immunopeptidome in cancer
GEO Series GSE143263. Homo sapiens. 10 samples. Type: Expression profiling by high throughput sequencing.
C-terminal binding protein (CTBP2) is a novel tumor suppressor targeting the MYC-IRF4 axis in multiple myeloma
GEO Series GSE255266. Homo sapiens. 8 samples. Type: Expression profiling by high throughput sequencing.
Single-cell RNAseq and longitudinal proteomic analysis of a novel semi-spontaneous urothelial cancer model reveals tumor cell heterogeneity and pretumoral urine protein alterations
GEO Series GSE174182. Mus musculus. 7 samples. Type: Expression profiling by high throughput sequencing.
An aspartyl protease defines a novel pathway for export of Toxoplasma proteins into the host cell
GEO Series GSE73986. Homo sapiens. 9 samples. Type: Expression profiling by high throughput sequencing.
Interaction of modified oligonucleotides with nuclear proteins, formation of novel nuclear structures and sequence-independent effects on RNA processing
GEO Series GSE121713. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
Unanchored K63-linked polyubiquitin chains: a novel second messenger involved in G protein-coupled receptors early signaling events
GEO Series GSE301643. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
TbSAP is a novel chromatin protein repressing metacyclic Variant Surface Glycoprotein expression sites in bloodstream form Trypanosoma brucei
GEO Series GSE160713. Trypanosoma brucei. 15 samples. Type: Expression profiling by high throughput sequencing.
Novel RNA partners of the Mei2 RNA binding protein during early meiosis in Schizosaccharomyces pombe
GEO Series GSE114299. Schizosaccharomyces pombe. 2 samples. Type: Other.
Novel RNA- and FMRP-binding protein TRF2-S regulates axonal mRNA transport and presynaptic plasticity
GEO Series GSE72887. Rattus norvegicus. 7 samples. Type: Expression profiling by array.
The novel NLR-related protein NWD1 is associated with prostate cancer progression and impacts androgen receptor signaling.
GEO Series GSE53115. Homo sapiens. 6 samples. Type: Expression profiling by array.
WTAP is a novel oncogenic protein in Acute Myeloid Leukemia
GEO Series GSE46718. Homo sapiens. 4 samples. Type: Expression profiling by high throughput sequencing.
Targeting METTL3 protein by PROTAC: A Novel Therapeutic Approach for Acute Myeloid Leukemia
GEO Series GSE273361. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
ERAP2 is a novel target involved in autophagy and activation of pancreatic stellate cells via unfolded protein response signaling pathway
GEO Series GSE172168. Homo sapiens. 4 samples. Type: Expression profiling by array.
Bcl11b, a Novel GATA3-Interacting Protein, Suppresses Th1 while Limiting Th2 Cell Differentiation
GEO Series GSE109109. Mus musculus. 35 samples. Type: Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing.
NKX3-1, a Novel Transcriptional Factor of AR, Promotes Prostate Cancer Cell Survival via RAB3B GTPase-mediated protein trafficking (mRNA)
GEO Series GSE28596. Homo sapiens. 8 samples. Type: Expression profiling by array.
Protein Syndesmos is a novel RNA binding protein that regulates primary cilia formation [Ribo-seq]
GEO Series GSE117998. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Data from: An antibody screen of a Plasmodium vivax antigen library identifies novel merozoite proteins associated with clinical protection
Background. Elimination of Plasmodium vivax malaria would be greatly facilitated by the development of an effective vaccine. A comprehensive and systematic characterization of antibodies to P. vivax antigens in exposed populations is useful in guiding rational vaccine design. Methodology/Principal Findings. In this study, we investigated antibodies to a large library of P. vivax entire ectodomain merozoite proteins in 2 Asia-Pacific populations, analysing the relationship of antibody levels with markers of current and cumulative malaria exposure, and socioeconomic and clinical indicators. 29 antigenic targets of natural immunity were identified. Of these, 12 highly-immunogenic proteins were strongly associated with age and thus cumulative lifetime exposure in Solomon Islanders (P<0.001-0.027). A subset of 6 proteins, selected on the basis of immunogenicity and expression levels, were used to examine antibody levels in plasma samples from a population of young Papua New Guinean children with well-characterized individual differences in exposure. This analysis identified a strong association between reduced risk of clinical disease and antibody levels to P12, P41, and a novel hypothetical protein that has not previously been studied, PVX_081550 (IRR 0.46-0.74; P<0.001-0.041). Conclusion/Significance. These data emphasize the benefits of an unbiased screening approach in identifying novel vaccine candidate antigens. Functional studies are now required to establish whether PVX_081550 is a key component of the naturally-acquired protective immune response, a biomarker of immune status, or both.
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.