Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
154
datasets available to search
ShareScore release 0.9.0
Dataset results
154 results for “off-target”
PEAC-seq: an unbiased in vivo CRISPR off-target detection technique
GEO Series GSE179436. Homo sapiens. 68 samples. Type: Other.
siRNA off-target effects can be reduced at concentrations that match their individual potency
GEO Series GSE28786. Homo sapiens. 54 samples. Type: Expression profiling by array.
Tracking-seq reveals the heterogeneity of off-target effects in CRISPR/Cas9-mediated genome editing
GEO Series GSE236360. Homo sapiens; Mus musculus. 111 samples. Type: Other; Genome binding/occupancy profiling by high throughput sequencing.
Digenome for off-target analysis: Start codon disruption with CRISPR/Cas9 prevents murine Fuchs' endothelial corneal dystrophy
GEO Series GSE146997. Homo sapiens. 2 samples. Type: Other.
shRNA Off-Target Effects In Vivo: Impaired Endogenous siRNA Expression and Spermatogenic Defects
GEO Series GSE64324. Mus musculus. 6 samples. Type: Expression profiling by array.
DNA copy number detection from exome sequencing - Exploiting the off-targets (SNP)
GEO Series GSE60168. Homo sapiens. 6 samples. Type: Genome variation profiling by SNP array.
Synthesis of 2'-formamidonucleoside phosphoramidites for suppressing the seed-based off-target effects of siRNAs [RNA-seq]
GEO Series GSE274426. Homo sapiens. 4 samples. Type: Expression profiling by high throughput sequencing.
Widespread siRNA "off-target" transcript silencing mediated by seed region sequence complementarity
GEO Series GSE5814. Homo sapiens. 68 samples. Type: Expression profiling by array.
siPools: highly complex but accurately defined siRNA pools eliminate Off-target effects
GEO Series GSE57674. Homo sapiens. 21 samples. Type: Expression profiling by array.
shRNA-based miRNA overexpression results in significant off-target effects caused by isomiR production
GEO Series GSE241303. Homo sapiens. 36 samples. Type: Expression profiling by high throughput sequencing; Non-coding RNA profiling by high throughput sequencing.
microRNA-like off-target transcript regulation by siRNAs
GEO Series GSE14073. Homo sapiens; Mus musculus. 81 samples. Type: Non-coding RNA profiling by array; Expression profiling by array.
Transcriptome-wide off-target RNA editing induced by CRISPR-guided DNA base editors
GEO Series GSE121668. Homo sapiens. 71 samples. Type: Expression profiling by high throughput sequencing.
Off-target effect of engineered AsCas12f variants
GEO Series GSE211600. Homo sapiens. 34 samples. Type: Other.
PEAC-seq: an unbiased in vivo CRISPR off-target detection technique
GEO Series GSE179523. Mus musculus. 130 samples. Type: Other.
DNA copy number detection from exome sequencing - Exploiting the off-targets
GEO Series GSE60259. Homo sapiens; Mus musculus. 10 samples. Type: Genome variation profiling by genome tiling array; Genome variation profiling by SNP array.
A mouse model for assessing mTOR kinase-independent role and off-target effect of mTOR kinase inhibitors [II]
GEO Series GSE172248. Mus musculus. 18 samples. Type: Expression profiling by high throughput sequencing.
Evaluation of off-target effects of gapmer antisense oligonucleotides using human cells
GEO Series GSE190473. Homo sapiens. 12 samples. Type: Expression profiling by array.
Sensitive and unbiased genome-wide profiling of base-editor-induced off-target activity with CHANGE-seq-BE [CHANGE-seq-BE for ABE targets]
GEO Series GSE307740. Homo sapiens. 18 samples. Type: Other.
Selict-seq profiles genome-wide off-target effects in adenosine base editing
GEO Series GSE278492. Homo sapiens. 30 samples. Type: Other.
Evidence of off-target effects associated with long dsRNAs in Drosophila cell-based assays
GEO Series GSE5554. Drosophila melanogaster. 6 samples. Type: Expression profiling by array.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.