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237
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ShareScore release 0.9.0
Dataset results
237 results for “sensitivity analysis”
Data from: Sensitivity analysis of effective population size to demographic parameters in house sparrow populations
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Data from: Using sensitivity analysis to identify key factors for the propagation of a plant epidemic
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Raw data on computational analysis the relationships of energy and mechanical properties with sensitivity for 1, 1-diamino-2, 2-dinitroethene based polymer bonded explosives
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Data from: Temporal shifts and temperature sensitivity of avian spring migratory phenology: a phylogenetic meta-analysis
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Data from: Insulin sensitizers for improving endocrine metabolism in overweight women with PCOS: a network meta-analysis
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Global gene expression analysis highlights microgravity sensitive key genes in soleus and EDL of 30 days space flown mice
Microgravity exposure as well as chronic muscle disuse are two of the main causes of physiological adaptive skeletal muscle atrophy in humans and murine animals in physiological condition. The aim of this study was to investigate at both morphological and global gene expression level skeletal muscle adaptation to microgravity in mouse soleus and extensor digitorum longus (EDL). Adult male mice C57BL/N6 were flown aboard the BION-M1 biosatellite for 30 days on orbit (BF) or housed in a replicate flight habitat on Earth (BG) as reference flight control. In this study we investigated for the first time gene expression adaptation to 30 days of microgravity exposure in mouse soleus and EDL highlighting potential new targets for improvement of countermeasures able to ameliorate or even prevent microgravity-induced atrophy in future spaceflights. Overall Design: C57BL/N6 mice were randomly divided in 3 groups: Bion Flown (BF) mice flown aboard the Bion M1 biosatellite in microgravity environment for 30 days; Bion Ground (BG) mice housed in the same habitat of flown animals but exposed to earth gravity; and Flight Control (FC) mice housed in a standard animal facility.
Global gene expression analysis highlights microgravity sensitive key genes in longissimus dorsi and tongue of 30 days space-flown mice
Microgravity as well as chronic muscle disuse are two causes of low back pain originated at least in part from paraspinal muscle deconditioning. At present no study investigated the complexity of the molecular changes in human or mouse paraspinal muscles exposed to microgravity. The aim of this study was to evaluate longissimus dorsi and tongue (as a new potential in-flight negative control) adaptation to microgravity at global gene expression level. C57BL/N6 male mice were flown aboard the BION-M1 biosatellite for 30 days (BF) or housed in a replicate flight habitat on ground (BG). Global gene expression analysis identified 89 transcripts differentially regulated in longissimus dorsi of BF vs. BG mice (False Discovery Rrate < 0,05 and fold change < -2 and > +2) while only a small number of genes were found differentially regulated in tongue muscle ( BF vs. BG = 27 genes). Overall Design: C57BL/N6 mice were randomly divided in 3 groups: Bion Flown (BF) mice flown aboard the Bion M1 biosatellite in microgravity environment for 30 days; Bion Ground (BG) mice housed in the same habitat of flown animals but exposed to earth gravity; and Flight Control (FC) mice housed in a standard animal facility.
Differential gene expression analysis between Miltefosine resistant and sensitive leishmania donovani
GEO Series GSE30685. Leishmania donovani; Leishmania. 6 samples. Type: Expression profiling by array.
Genome-scale knockout simulation and clustering analysis of drug-resistant breast cancer cells reveal drug sensitization targets
GEO Series GSE288840. Homo sapiens. 9 samples. Type: Expression profiling by high throughput sequencing.
A Bioinformatic Analysis of Arginine-Sensitive Regulation of rat Hepatic Gene Expression
GEO Series GSE2275. Rattus norvegicus. 12 samples. Type: Expression profiling by array.
Human skeletal muscle gene expression analysis on Lean, obese insulin sensitive, obese insulin resistant and obese Type II diabetic subjects
GEO Series GSE73034. Homo sapiens. 28 samples. Type: Expression profiling by array.
Comparative RNA-seq analysis of the drought-sensitive lentil (Lens culinaris) root and leaf under short- and long-term water deficits
GEO Series GSE115199. Lens culinaris. 18 samples. Type: Expression profiling by high throughput sequencing.
SmallRNA analysis of simulated microgravity sensitized endothelial cells.
GEO Series GSE113800. Homo sapiens. 2 samples. Type: Non-coding RNA profiling by high throughput sequencing.
A comprehensive genomic, transcriptomic and proteomic analysis of a hyperosmotic stress sensitive α-proteobacterium.
GEO Series GSE49654. Caulobacter vibrioides CB15; Caulobacter vibrioides NA1000. 9 samples. Type: Expression profiling by array.
Analysis of ALK TKI sensitive and ALK TKI resistant isogenic pairs of H3122 (EML4-ALK E13;A20) cells
GEO Series GSE49508. Homo sapiens. 9 samples. Type: Expression profiling by array.
CloneSeq: A Highly Sensitive Single-cell Analysis Platform for Comprehensive Characterization of Cells from 3D Culture
GEO Series GSE155888. Homo sapiens; Mus musculus. 27 samples. Type: Expression profiling by high throughput sequencing.
Comparative dynamic transcriptome analysis (cDTA-seq) and total RNA-seq of ATP-analog sensitive Kin28 budding yeast
GEO Series GSE83416. Saccharomyces cerevisiae. 34 samples. Type: Expression profiling by high throughput sequencing.
High-throughput gene expression analysis with TempO-LINC sensitively resolves complex brain, lung and kidney heterogeneity at single-cell resolution
GEO Series GSE275129. Mus musculus. 3 samples. Type: Other.
Transcriptomic Analysis in Renal T Lymphocytes Exposes Sodium-Independent Dietary Differences in Dahl Salt-Sensitive Rats
GEO Series GSE127000. Rattus norvegicus. 40 samples. Type: Expression profiling by high throughput sequencing.
Single-cell Analysis of a High-grade Serous Ovarian Cancer Cell Line Reveals Transcriptomic Changes and Cell Subpopulations Sensitive to Epigenetic Combination Treatment
GEO Series GSE207993. Homo sapiens. 4 samples. Type: Expression profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.