Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
334
datasets available to search
ShareScore release 0.9.0
Dataset results
334 results for “targeted cancer therapy”
GRHL2 is a key lineage determining factor which collaborates with FOXA1 to establish a targetable collateral pathway in the setting of endocrine therapy-resistant breast cancer [ChIP-seq]
GEO Series GSE113092. Homo sapiens. 83 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
RNA sequencing data of paired parental and therapy resistant cancer cell lines transfected with negative control siRNA's or a pool of siRNA's targeting DNMT1, DNMT3A and DNMT3B
GEO Series GSE142586. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
Divergent resistance mechanisms to HER2-targeted therapies in breast cancer
GEO Series GSE161423. Mus musculus; Homo sapiens. 64 samples. Type: Expression profiling by high throughput sequencing; Genome variation profiling by high throughput sequencing.
Comparing Neoantigen Cancer Vaccines and Immune Checkpoint Therapy Unveils an Effective Vaccine and Anti-TREM2 Macrophage-Targeting Dual Therapy [neoAgSpCD8Tcells]
GEO Series GSE276904. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.
Single-cell profiling guided combinatorial immunotherapy for breast cancer resistance to Her2/neu and CDK4/6 targeted therapy
GEO Series GSE122336. Mus musculus. 21 samples. Type: Expression profiling by high throughput sequencing.
Targeting MDM4/MDM2 binding interface for reactivation of p53 in cancer therapy
GEO Series GSE62855. Homo sapiens. 24 samples. Type: Expression profiling by array.
Computational modeling integrating transcriptomic and vulnerability responses can predict suppressors of cell death as candidate targets for cancer therapy
GEO Series GSE255459. Homo sapiens. 18 samples. Type: Expression profiling by high throughput sequencing.
Cancer-stromal cell interactions in breast cancer brain metastases induce glycocalyx-mediated resistance to HER2-targeting therapies [RNA-seq]
GEO Series GSE249573. Homo sapiens. 40 samples. Type: Expression profiling by high throughput sequencing.
Combined therapy with DR5- targeting antibody-drug conjugate and CDK inhibitors as a novel strategy for advanced MSS and MSI-H colorectal cancer
GEO Series GSE289746. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
Acquired FGFR and FGF alterations confer resistance to estrogen receptor (ER) targeted therapy in ER+ metastatic breast cancer
GEO Series GSE153509. Homo sapiens. 647 samples. Type: Expression profiling by high throughput sequencing.
GRHL2 is a key lineage determining factor which collaborates with FOXA1 to establish a targetable collateral pathway in the setting of endocrine therapy-resistant breast cancer
GEO Series GSE106695. Homo sapiens. 125 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Divergent resistance mechanisms to HER2-targeted therapies in breast cancer (bulkRNA-Seq and Exome-Seq)
GEO Series GSE161420. Homo sapiens. 60 samples. Type: Expression profiling by high throughput sequencing; Genome variation profiling by high throughput sequencing.
Epigenetic therapy targets the 3D epigenome in endocrine-resistant breast cancer [CUT&RUN]
GEO Series GSE237769. Homo sapiens. 13 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Synergistic targeting of estrogen-receptor positive breast cancers by MDM2 inhibition in combination with endocrine therapy or CDK4/6 inhibition
GEO Series GSE140758. Homo sapiens. 29 samples. Type: Expression profiling by high throughput sequencing.
Targeting Metabolic Adaptations in the Breast Cancer–Liver Metastatic Niche Using Dietary Approaches to Improve Endocrine Therapy Efficacy
GEO Series GSE236681. Homo sapiens; Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.
Increased lactate secretion by cancer cells sustains non-cell-autonomous adaptive resistance to MET and EGFR targeted therapies.
GEO Series GSE115172. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.
GRHL2 is a key lineage determining factor which collaborates with FOXA1 to establish a targetable collateral pathway in the setting of endocrine therapy-resistant breast cancer (RNA-Seq data set 2)
GEO Series GSE106694. Homo sapiens. 18 samples. Type: Expression profiling by high throughput sequencing.
Targeting IGF2BP1 Enhances Immune Checkpoint Therapy in High-grade Serous Ovarian Cancer
GEO Series GSE285177. Mus musculus; Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Targeting IGF2BP1 Enhances Immune Checkpoint Therapy in High-grade Serous Ovarian Cancer [mouse]
GEO Series GSE285176. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.
Identification of MUC1-C Dependence in Drug-Resistant Advanced Prostate Cancer Uncovers a New Target for Antibody-Drug Conjugate Therapy
GEO Series GSE276890. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.