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1,274
datasets available to search
ShareScore release 0.9.0
Dataset results
1,274 results for “Disease Model”
Modeling Malignant Bone Disease Using Microgravity Bioreactors, Genetically Engineered Cell Lines, Patient-Derived Tumor Xenografts and Stem Cells
GEO Series GSE118107. Homo sapiens. 12 samples. Type: Expression profiling by array.
bacTRAP profiling of astrocytes in five mouse brain regions in wildtype controls and hippocampus region in a Alzheimer's disease mouse model
GEO Series GSE310518. Mus musculus. 30 samples. Type: Expression profiling by high throughput sequencing.
scRNA-seq assessment of the impact of anti-IL6R and anti-OSM in a model of fibrotic lung disease during fibrosis (day 14) [NGS4272]
GEO Series GSE263041. Mus musculus. 30 samples. Type: Expression profiling by high throughput sequencing.
Triple kinase target modulation in an animal model of Alzheimer disease
GEO Series GSE227292. Mus musculus. 9 samples. Type: Expression profiling by high throughput sequencing.
Gene expression profiles in the striatum of the R6/2 mouse model of Huntington's disease injected with LNA-oligonucleotides complementary to the CAG repeats (LNA-CTG)
GEO Series GSE85126. Mus musculus. 15 samples. Type: Expression profiling by array.
The NRF2 inducer CDDO-2P-Im provokes a reduction in amyloid beta levels in Alzheimer’s disease model mice
GEO Series GSE271154. Mus musculus. 43 samples. Type: Expression profiling by high throughput sequencing.
“Bench-to-Bedside and Back” analysis of NAFLD model reveals common transcriptomic shifts between mouse and human during disease progression
GEO Series GSE159911. Mus musculus. 152 samples. Type: Expression profiling by high throughput sequencing.
Lung miRNA expression profiling in a mouse model of chronic obstructive pulmonary disease
GEO Series GSE186955. Mus musculus. 31 samples. Type: Non-coding RNA profiling by array.
Dataset related to article "Immune-mediated myogenesis and acetylcholine receptor clustering promote a slow disease progression in ALS mouse models"
<p>The file contains the raw datasets related to the figures of the work (i.e. behavioural analysis, western blot, immunofluorescence, RT-qPCR). Each sub-folder of the Excel file refers to a specific figure.</p> <p>Full blot images are provided in the electronic version of the paper at the following link:</p> <p><a href="https://static-content.springer.com/esm/art%3A10.1186%2Fs41232-023-00270-w/MediaObjects/41232_2023_270_MOESM2_ESM.pdf" target="_blank" rel="nofollow noopener noreferrer">https://static-content.springer.com/esm/art%3A10.1186%2Fs41232-023-00270-w/MediaObjects/41232_2023_270_MOESM2_ESM.pdf</a></p>
Microglia-specific loss of PU.1 function rescues neurodegenerative phenotypes in a mouse model of Alzheimer’s disease
GEO Series GSE117868. Mus musculus. 19 samples. Type: Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing.
Neuron-targeted caveolin-1 enhances the neuroprotective, neuronal and synaptic plasticity transcriptome and improves cognitive function in symptomatic Alzheimer’s Disease models
GEO Series GSE278571. Mus musculus. 10 samples. Type: Expression profiling by high throughput sequencing.
Analysis of striatal zinc finger protein (ZFP) repression of mutant Huntingtin (HTT) in the zQ175DN knock-in mouse model of Huntington's disease (snRNA-seq)
GEO Series GSE270728. Mus musculus. 120 samples. Type: Expression profiling by high throughput sequencing.
Inhibition of transglutaminase 2 mitigates transcriptional dysregulation in models of Huntington disease
GEO Series GSE21237. Mus musculus. 23 samples. Type: Expression profiling by array.
Methylomic signatures of tau and beta amyloid in transgenic mouse models of Alzheimer’s disease neuropathology [HorvathMammalMethylChip40 Methylation Beadchip]
GEO Series GSE246559. Homo sapiens; Mus musculus; Rattus norvegicus. 159 samples. Type: Methylation profiling by array.
In vivo CRISPR screening in autoimmune disease model reveals differential dependence of Th1 and Th17 cells on amino acid transporter SNAT1
GEO Series GSE190131. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.
Introducing cellular senescence in human induced pluripotent stem cells and differentiated neural lineage for modeling of age-associated diseases
GEO Series GSE251814. Homo sapiens. 16 samples. Type: Expression profiling by high throughput sequencing.
RNA-Binding Activity of PHGDH Drives Amyloid-beta Production in A Human Brain Organoid Model of Sporadic Alzheimer’s Disease
GEO Series GSE302314. Homo sapiens. 8 samples. Type: Other.
Transcriptional profiling of brain tissues from a Q130 Long Evans Knock-in rat model of Huntington’s disease at 10-, 19- and 24-months of age
GEO Series GSE169386. Rattus norvegicus. 145 samples. Type: Expression profiling by high throughput sequencing.
RNA-seq reveals ultrasound-guided renal parenchymal infusion of mesenchymal stem cells in chronic kidney disease rat model
GEO Series GSE275449. Rattus norvegicus. 9 samples. Type: Expression profiling by high throughput sequencing.
Comparative analyses of disease-linked missense mutations in the RNA exosome modeled in budding yeast reveal distinct functional consequences in translation
GEO Series GSE246957. Saccharomyces cerevisiae. 39 samples. Type: Expression profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.