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Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
1,274
datasets available to search
ShareScore release 0.9.0
Dataset results
1,274 results for “Disease Model”
Fully defined human PSC-derived microglia and tri-culture system reveals cell type specific potentiation of complement C3 production in a model of Alzheimer’s disease
GEO Series GSE139552. Homo sapiens. 27 samples. Type: Expression profiling by high throughput sequencing.
Brain pathology and cerebellar Purkinje cell loss in a mouse model of chronic neuronopathic Gaucher disease [whole brain]
GEO Series GSE157987. Mus musculus. 17 samples. Type: Expression profiling by high throughput sequencing.
Deficits in histone acetylation and methylation are restricted to specific loci in Huntington's disease models
GEO Series GSE63675. Mus musculus. 3 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Gene expression profiling of the whole brain of the Huntington disease model mouse R6/2 at 5 weeks post-natal age using transcriptome tomography
GEO Series GSE227657. Mus musculus. 42 samples. Type: Expression profiling by array.
Regional interneuron transcriptional changes reveal pathologic markers of disease progression in a mouse model of Alzheimer’s disease -- Early-stage AD
GEO Series GSE273591. Mus musculus. 303 samples. Type: Other.
A Single-Cell Atlas of Murine Liver Non-parenchymal Cells in Typical Disease Models
GEO Series GSE166178. Mus musculus. 18 samples. Type: Expression profiling by high throughput sequencing.
Systematic characterization of LUHMES cell-based Parkinson’s disease models reveals potential novel drug targets.
GEO Series GSE287941. Homo sapiens. 22 samples. Type: Expression profiling by high throughput sequencing.
Gene expression changes in multiple brain regions of a mouse MPTP model of Parkinson's disease
GEO Series GSE7707. Mus musculus. 18 samples. Type: Expression profiling by array.
Pathophysiological features of disease in a large animal model of COPD
GEO Series GSE242416. Ovis aries. 54 samples. Type: Expression profiling by high throughput sequencing.
Synergistic behavioral and neuroinflammatory effects of amyloid neuropathology and sepsis survival in a murine model of Alzheimer’s disease
GEO Series GSE176506. Mus musculus. 112 samples. Type: Expression profiling by high throughput sequencing.
Transcriptomic profiling of dorsal root ganglia of transgenic sickle and control mouse models for studying genetic signatures of pain in sickle cell disease
GEO Series GSE86418. Mus musculus. 49 samples. Type: Expression profiling by high throughput sequencing.
APP and its intracellular domain modulate Alzheimer’s disease risk gene networks in transgenic APPsw and PSEN1M146I porcine models [fibroblasts]
GEO Series GSE254570. Sus scrofa. 29 samples. Type: Expression profiling by high throughput sequencing.
Comparative analysis of liver mitochondrial ncRNA in metabolic disease model mice.
GEO Series GSE158914. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.
Distinct transcriptomic and epigenomic responses of mature oligodendrocytes during disease progression in a mouse model of multiple sclerosis [ATAC-seq]
GEO Series GSE283085. Mus musculus. 15 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Dysregulated ac4C modification of mRNA in a mouse model of early stage Alzheimer's disease [mRNA-seq]
GEO Series GSE281343. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Delineating the angiogenic gene expression profile prior to pulmonary vascular remodeling in a lamb model of congenital heart disease
GEO Series GSE22590. Bos taurus; Ovis aries. 16 samples. Type: Expression profiling by array.
Early infiltrating macrophage subtype correlates with late stage phenotypic outcome in a mouse model of hepatorenal fibrocystic disease
GEO Series GSE174168. Mus musculus. 16 samples. Type: Expression profiling by high throughput sequencing.
RNAseq of FACS Drd1 and Drd2 receptor expressing medium spiny neurons (direct and indirect medium spiny neurons) from 5-6 month Q175 Huntington's disease model mice, compared to WT littermates.
GEO Series GSE103345. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.
APP and its intracellular domain modulate Alzheimer’s disease risk gene networks in transgenic APPsw and PSEN1M146I porcine models
GEO Series GSE254571. Sus scrofa. 41 samples. Type: Expression profiling by high throughput sequencing.
Transcriptomic analysis of the effect of ASO-mediated CD33 knock-down on the microglial gene network in an APP/PS1 mouse model of Alzheimer's disease.
GEO Series GSE74441. Mus musculus. 260 samples. Type: Expression profiling by array.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.