Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
3,960
datasets available to search
ShareScore release 0.9.0
Dataset results
3,960 results for “lung patient”
Metabolomics dataset for identification of metabolites associated with survival in lung cancer patients under treatment
<p>Non small cell lung cancer patients' serum samples were collected before treatment. The samples were analyzed by metabolomics using high resolution NMR and untargeted lipidomics using high resolution UPLC-MS. The data was used to identify the predictors of overall survival in the patients after they underwent treatment.</p>
Figure 1 from: Zlatanova T, Arabadjiev J (2024) The prognostic role of markers of systemic inflammation in patients with metastatic lung cancer receiving immunotherapy: A comprehensive review of the literature. Pharmacia 71: 1-7. https://doi.org/10.3897/pharmacia.71.e115558
Figure 1 Biological Hallmarks of Cancer, Source: Adapted from Hallmarks of Cancer: The Next Generation, Hanahan D., Weinberg R.A. , Cell, Volume 144, ISSUE 5, P646-674, March 04, 2011, https://doi.org/10.1016/j.cell.2011.02.013.
A detailed ultrastructural examination of lung cryobiopsy samples from a COVID-19 patient case series – Data set 04
<p>We investigated six cryobiopsy samples from six deceased patients (patients C03 to C08 from Barisione et al. 2020 <a href="https://doi.org/10.1007/s00428-020-02934-1">doi.org/10.1007/s00428-020-02934-1</a>) by using thin section electron microscopy (Cortese et al. 2022 <a href="http://doi.org/10.1007/s00428-022-03308-5">doi.org/10.1007/s00428-022-03308-5</a>). A detailed description of the methods and the data set is provided in the download container.</p> <p>Data set 04 contains a stitched image montage of the first and of the last semithin section from the analysis of patient C06, which was acquired by bright-field light microscopy.</p>
A detailed ultrastructural examination of lung cryobiopsy samples from a COVID-19 patient case series – Data set 16
<p>We investigated six cryobiopsy samples from six deceased patients (patients C03 to C08 from Barisione et al. 2020 <a href="https://doi.org/10.1007/s00428-020-02934-1">doi.org/10.1007/s00428-020-02934-1</a>) by using thin section electron microscopy (Cortese et al. 2022 <a href="http://doi.org/10.1007/s00428-022-03308-5">doi.org/10.1007/s00428-022-03308-5</a>). A detailed description of the methods and the data set is provided in the download container.</p> <p>Data set 16 contains stitched image montages of a thin section through the lung of patient C06 which were acquired by scanning electron microscopy. The file “Data_set_16.tif” contains a montage of the entire thin section while the other files contain selected areas of the section recorded at higher resolution.</p>
Targeted gene expression profiling of human myeloid cells from blood and lung compartments of patients with Tuberculosis and other lung diseases
<p>This dataset comprises expression profiles of 43 genes related to MSDC functioning and 5 reference genes in 8 blood samples and 8 brochio-alveolar lavage fluid (BALF) samples from TB patients. Also included are results from blood and BALF of 2 'other lung disease' patients each.</p>
The bradykinin-2 receptor antagonist, icatibant, improves lung function in patients with SARS-CoV2 associated ARDS - First results of a prospective off-label use patient-related observational study.
<p>SARS-CoV2-associated adult respiratory distress syndrome (COVID19-ARDS) frequently leads to fatal respiratory failure in COVID19. Currently, there is no curative treatment option for severe COVID19-ARDS other than mechanical ventilation therapy and extracorporal membrane oxygenation (ECMO). We investigated whether modification of the kallikrein-kinin system in vivo attenuates the progression of SARS-CoV2-induced ARDS. The aim of the study was to investigate the effect of blockade of the B2R on the course of COVID19-ARDS. In an observational study including 53 COVID19-ARDS patients, patients received the bradykinin-2-receptor antagonist (B2RAg) icatibant. After icatibant substitution, respiratory rate in COVID19-ARDS reduced by a maximum of 32% (24.9/min to 16.8/min) with a concomitant reduction in oxygen substitution by 59% (6.1 LO<sub>2</sub>/min to 2.5 LO<sub>2</sub>/min). The data show that the use of icatibant in the early phase of COVID19-ARDS is suitable to stabilize pulmonary gas exchange. Furthermore, early icatibant substitution seems to be able to reduce the rate of necessary invasive ventilation in COVID19-ARDS. Observational data suggest that inhibition of bradykinin signalling leads to stabilization of lung function in SARS-CoV2-associated ARDS. Further prospective placebo-controlled studies are needed to investigate the impact of the kallikrein-kinin system on the development of COVID19-ARDS in vivo.</p>
Lung-MAP: Durvalumab as Second-Line Therapy in Treating Patients With Recurrent Stage IV Squamous Cell Lung Cancer and No Matching Biomarkers
ClinicalTrials.gov study NCT02766335. IPD Sharing: Not stated. Countries: 1. Publications: 0.
A Study Comparing Two Different Chemotherapy Types in Chinese Patients With Advanced Non Small Cell Lung Cancer
ClinicalTrials.gov study NCT01005680. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Neoadjuvant or Adjuvant Chemotherapy in Patients With Operable Non-small-cell Lung Cancer
ClinicalTrials.gov study NCT00913705. IPD Sharing: Not stated. Countries: 0. Publications: 1.
Medical Nutrition Therapy or Standard Care in Treating Patients With Lung Cancer, Pancreatic Cancer, or Stage III or Stage IV Prostate Cancer
ClinicalTrials.gov study NCT00769652. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Azacitidine and Entinostat in Treating Patients With Stage I Non-Small Cell Lung Cancer That Has Been Removed By Surgery
ClinicalTrials.gov study NCT01207726. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Pre-Incisional Ketorolac for Patients Undergoing Surgery for Non-Small Cell Lung Cancer and Renal Cell Carcinoma
ClinicalTrials.gov study NCT04495894. IPD Sharing: NO. Countries: 1. Publications: 0.
Cryotherapy in Treating Patients With Primary Lung Cancer or Lung Metastases That Cannot Be Removed By Surgery
ClinicalTrials.gov study NCT00303901. IPD Sharing: Not stated. Countries: 1. Publications: 0.
R-(-)-Gossypol Acetic Acid in Treating Patients With Recurrent Extensive-Stage Small Cell Lung Cancer
ClinicalTrials.gov study NCT00773955. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Chemotherapy and Radiotherapy to Treat Patients With Limited Stage of Small Cell Lung Cancer (SCLC)
ClinicalTrials.gov study NCT00494026. IPD Sharing: Not stated. Countries: 4. Publications: 0.
Targeted Therapy in Treating Patients With Incurable Non-Small Cell Lung Cancer With Genetic Mutations
ClinicalTrials.gov study NCT02949843. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Image Guided Hypofractionated Radiation Therapy, Nelfinavir Mesylate, Pembrolizumab, Nivolumab and Atezolizumab in Treating Patients With Advanced Melanoma, Lung, or Kidney Cancer
ClinicalTrials.gov study NCT03050060. IPD Sharing: NO. Countries: 1. Publications: 0.
Fish Oil Versus Statins Versus Placebos in Reducing Atrial Fibrillation in Patients Undergoing Thoracic Surgery for Lung Cancer
ClinicalTrials.gov study NCT01259284. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Telehealth Based Synchronous Navigation to Improve Molecularly-Informed Care for Patients With Lung Cancer
ClinicalTrials.gov study NCT05790460. IPD Sharing: NO. Countries: 1. Publications: 0.
Efficacy Study of Avastin® With Pemetrexed +/- Carboplatin to Treat Elderly Patients With Non-small Cell Lung Cancer
ClinicalTrials.gov study NCT00976456. IPD Sharing: Not stated. Countries: 1. Publications: 0.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.