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1,274 results for “Disease Model”

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geo12/100

Single-Cell Atlas of Neuroglial Dynamics in SNCA-A53T Parkinson's Disease Model

GEO Series GSE306642. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenSep 2025View details →
geo12/100

Identification of transcriptional alterations that distinguish sensitive from insensitive neuronal populations in a genetic model of Parkinson’s disease.

GEO Series GSE80277. Drosophila melanogaster. 12 samples. Type: Expression profiling by array.

openGEO-OpenAug 2020View details →
geo12/100

Methylomic signatures of tau and beta amyloid in transgenic mouse models of Alzheimer’s disease neuropathology

GEO Series GSE246561. Homo sapiens; Mus musculus; Rattus norvegicus. 283 samples. Type: Methylation profiling by array; Methylation profiling by high throughput sequencing.

openGEO-OpenOct 2024View details →
geo12/100

Effect of low-intensity pulsed ultrasound modulates disease progression in the SOD1G93A mouse model of amyotrophic lateral sclerosis

GEO Series GSE263117. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJul 2024View details →
geo12/100

Lifestyle shapes premorbid social and microglial deficits in an Alzheimer’s disease mouse model

GEO Series GSE301217. Mus musculus. 2 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJul 2025View details →
geo12/100

The microglial transcriptome of a novel murine model of Alzheimer's Disease: phagocytically active and inactive microglia from homozygous App-SAA mice and WT littermate controls.

GEO Series GSE158153. Mus musculus. 30 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJan 2021View details →
geo12/100

Transcriptional gender specific changes in the APP/PS1 mouse model of Alzheimer’s disease pathology

GEO Series GSE85162. Mus musculus. 58 samples. Type: Expression profiling by array.

openGEO-OpenMar 2020View details →
geo12/100

Whole organism snRNA-seq reveals systemic peripheral changes in Alzheimer’s Disease fly models

GEO Series GSE261656. Drosophila melanogaster. 28 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenMar 2024View details →
geo12/100

Targeting GPX4-mediated ferroptosis alleviates liver injury in a rat model of intestinal failure-associated liver disease

GEO Series GSE223895. Rattus norvegicus. 11 samples. Type: Non-coding RNA profiling by high throughput sequencing.

openGEO-OpenJan 2024View details →
geo12/100

Indole-3-carboxaldehyde (ICA) mitigates morbidity and mortality in a mouse model of Graft-versus-Host-Disease

GEO Series GSE111512. Mus musculus. 18 samples. Type: Expression profiling by array.

openGEO-OpenMar 2018View details →
geo12/100

Single-cell transcriptomics revealed molecular vulnerability in a human midbrain-like organoid model of Parkinson's Disease [scRNA-Seq]

GEO Series GSE271116. Homo sapiens. 15 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenDec 2025View details →
geo12/100

GPR40 Agonist ameliorates neurodegeneration and motor impairment by regulating NLRP3 inflammasome in Parkinson’s disease animal models.

GEO Series GSE275257. Mus musculus. 18 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenAug 2024View details →
geo12/100

Dysregulated ac4C modification of mRNA in a mouse model of early stage Alzheimer's disease.

GEO Series GSE285655. Mus musculus. 18 samples. Type: Other.

openGEO-OpenJan 2025View details →
geo12/100

A ketogenic diet improves memory in females in the APOE4 mouse model of Alzheimer’s disease.

GEO Series GSE301153. Mus musculus. 20 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenNov 2025View details →
geo12/100

Transcriptome profiling in knock-in mouse models of Huntington's disease [Hippocampus_mRNA]

GEO Series GSE73503. Mus musculus. 168 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenNov 2015View details →
geo12/100

Dissecting the genetics of cutaneous miRNA in a mouse model of autoimmune bullous disease

GEO Series GSE64276. synthetic construct; Mus musculus. 100 samples. Type: Non-coding RNA profiling by array.

openGEO-OpenDec 2014View details →
geo12/100

Expression data from microglia in Abeta and TAU mouse models of Alzheimer Disease

GEO Series GSE129296. Mus musculus. 23 samples. Type: Expression profiling by array.

openGEO-OpenMar 2021View details →
geo12/100

Effect of Bacteroides fragilis administration on microglia in WT and the APP-PS1 model of Alzheimer's disease [Bfrag]

GEO Series GSE215438. Mus musculus. 15 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenOct 2024View details →
geo12/100

Blood-derived stable induced neural stem cells: Preservation of age-related DNA methylation patterns and applicability to disease modeling

GEO Series GSE90129. Homo sapiens. 11 samples. Type: Expression profiling by array.

openGEO-OpenNov 2018View details →
geo12/100

NK2 model of congenital heart disease

GEO Series GSE528. Mus musculus. 26 samples. Type: Expression profiling by array.

openGEO-OpenJul 2003View details →

ScienceDex guides

Understand access before you commit

These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.

Compare curated datasets

Allen Brain Atlas

Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.

allen-brain-atlas
neuroscienceopenDocumentation, web resources, and API references are available online.
Last verified 2026-04-30Open record

Annotated Behaviour and Observability Dataset (ABODe)

ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.

abode-home-cage
behavioral-neuroscienceopenThe DataShare record exposes download links for annotations, documentation, license text, and the zipped per-snippet data directory.
Last verified 2026-04-30Open record

DANDI Archive for NWB datasets

DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.

dandi-nwb
electrophysiologyopenPublished Dandiset metadata and archive endpoints are available through the production DANDI API.
Last verified 2026-04-30Open record

International Brain Laboratory public data

The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.

ibl
behavioral-neuroscienceopenPublic sessions can be searched and loaded from the IBL public data server through ONE.
Last verified 2026-04-29Open record

OpenNeuro

OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.

openneuro
neuroscienceopenPublished datasets are available on demand over the internet.
Last verified 2026-04-29Open record