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1,235 results for “pulmonary hypertension”
Small RNA sequencing Analysis of lung Reveals Novel tRNA-derived Small RNAs with Biomarker Potential for Pulmonary Arterial Hypertension
GEO Series GSE270791. Rattus norvegicus. 6 samples. Type: Non-coding RNA profiling by high throughput sequencing.
Effect of PPARγ inhibition on pulmonary endothelial cell gene expression: Gene profiling in pulmonary hypertension
GEO Series GSE14546. Ovis aries; Bos taurus. 15 samples. Type: Expression profiling by array.
Elucidating the Role of Flk1 in Pulmonary arterial Hypertension
GEO Series GSE216878. Mus musculus. 21 samples. Type: Expression profiling by high throughput sequencing.
Early Angiogenic Proteins Associated with High Risk for Bronchopulmonary Dysplasia and Pulmonary Hypertension in Preterm Infants
GEO Series GSE121097. Homo sapiens. 102 samples. Type: Protein profiling by protein array.
Classical Dendritic Cells Contribute to Hypoxia-Induced Pulmonary Hypertension
GEO Series GSE256348. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Parathyroid hormone exacerbates pulmonary hypertension through hypoxia-induced parathyroid hormone receptor upregulation.
GEO Series GSE244861. Mus musculus. 9 samples. Type: Expression profiling by high throughput sequencing.
Endothelial matrix-metalloproteinase-10 promotes pulmonary arterial hypertension associated with systemic sclerosis
GEO Series GSE73674. Homo sapiens. 70 samples. Type: Expression profiling by array.
Large animal model of chronic thromboembolic pulmonary hypertension
<p>Echocardiographic, histological and mRNA expression data.</p>
Raw data: Role of cardiopulmonary exercise test in the prediction of hemodynamic impairment in patients with pulmonary arterial hypertension
<p>Periodic repetition of right heart catheterization (RHC) in pulmonary arterial hypertension (PAH) can be challenging. We evaluated the correlation between RHC and cardiopulmonary exercise test (CPET) aiming at CPET use as a potential noninvasive tool for hemodynamic burden evaluation. One hundred and forty‐four retrospective PAH patients who had performed CPET and RHC within 2 months were enrolled. The following analyses were performed: (a) CPET parameters in hemodynamic variables tertiles; (b) position of hemodynamic parameters in the peak end‐tidal carbon dioxide pressure (P<sub>ET</sub>CO<sub>2</sub>) versus ventilation/carbon dioxide output (VE/VCO<sub>2</sub>) slope scatterplot, which is a specific hallmark of exercise respiratory abnormalities in PAH; (c) association between CPET and a hemodynamic burden score developed including mean pulmonary arterial pressure (mPAP), pulmonary vascular resistance (PVR), cardiac index, and right atrial pressure. VE/VCO<sub>2</sub> slope and peak P<sub>ET</sub>CO<sub>2</sub> significantly varied in mPAP and PVR tertiles, while peak oxygen uptake (peak VO<sub>2</sub>) and O<sub>2</sub> pulse varied in the tertiles of all hemodynamic parameters. P<sub>ET</sub>CO<sub>2</sub> versus VE/VCO<sub>2</sub> slope showed a strong hyperbolic relationship (<em>R</em> <sup>2</sup> =&thinsp;0.7627). Patients with peak P<sub>ET</sub>CO<sub>2</sub> > median (26 mmHg) and VE/VCO<sub>2</sub> slope < median (44) presented lower mPAP and PVR (p < 0.005) than patients with peak P<sub>ET</sub>CO<sub>2</sub> < median and VE/VCO<sub>2</sub> slope > median. Multivariate analysis individuated peak VO<sub>2</sub> (<em>p</em> =&thinsp;0.0158) and peak P<sub>ET</sub>CO<sub>2</sub> (<em>p</em> =&thinsp;0.0089) as hemodynamic score independent predictors; the formula 11.584 − 0.0925 × peak VO<sub>2</sub> − 0.0811 × peak P<sub>ET</sub>CO<sub>2</sub> best predicts the hemodynamic score value from CPET data. A significant correlation was found between estimated and calculated scores (<em>p</em> < 0.0001), with a precise match for patients with mild‐to‐moderate hemodynamic burden (76% of cases). The results of the present study suggest that CPET could allow to estimate the hemodynamic burden in PAH patients.</p> <p> </p>
Environmental aromatic amine induces pulmonary arterial hypertension associated with estrogen signaling and Serpine1
GEO Series GSE287019. Rattus norvegicus. 24 samples. Type: Expression profiling by array.
Caveolin1 Deficiency: A Type I Endothelial Interferonopathy Associated with Pulmonary Arterial Hypertension
GEO Series GSE138991. Homo sapiens. 20 samples. Type: Expression profiling by array.
Small RNA Microarray Analysis of MCT-Induced Right Ventricular Failure Reveals Novel tRNA-derived Small RNAs with Biomarker Potential for Pulmonary Arterial Hypertension
GEO Series GSE245790. Rattus norvegicus. 6 samples. Type: Non-coding RNA profiling by high throughput sequencing.
Role of mast cells in pulmonary hypertension with left heart disease
GEO Series GSE84704. Rattus norvegicus. 12 samples. Type: Expression profiling by array.
Stub1 acetylation by CBP/p300 attenuates chronic hypoxia-induced pulmonary hypertension by suppressing HIF-2α transcriptional activity
GEO Series GSE221264. Mus musculus; Homo sapiens. 19 samples. Type: Expression profiling by high throughput sequencing.
The effect of pulmonary hypertension on mortality and intensive care unit admission in patients with SARS-CoV-2 infection: a systematic review and meta-analysis
<p>Dataset & R script for all analyses performed.</p>
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.