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1,356
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ShareScore release 0.9.0
Dataset results
1,356 results for “Human Activities”
Wnt/β-catenin signaling activation induces differentiation in human limbal epithelial stem cells cultured ex vivo
GEO Series GSE234403. Homo sapiens. 12 samples. Type: Expression profiling by array.
Activation of FXR regulates oxidative stress responses in human keratinocytes.
GEO Series GSE305364. Homo sapiens. 9 samples. Type: Expression profiling by high throughput sequencing.
Gene expression in human activated memory CD4+ T cells
GEO Series GSE113889. Homo sapiens. 8 samples. Type: Expression profiling by array.
Dataset related to the article "Activation of Nrf2/HO-1 Pathway and Human Atherosclerotic Plaque Vulnerability: an In Vitro and In Vivo Study"
<p>This record contains raw data related to the article “Activation of Nrf2/HO-1 Pathway and Human Atherosclerotic Plaque Vulnerability: an In Vitro and In Vivo Study"</p> <p>Abstract: Reactive oxygen species (ROS) induce nuclear factor erythroid 2–related factor 2 (Nrf2) activation as an adaptive defense mechanism, determining the synthesis of antioxidant molecules, including heme-oxygenase-1 (HO-1). HO-1 protects cells against oxidative injury, degrading free heme and inhibiting ROS production. HO-1 is highly expressed in macrophages during plaque growth. Macrophages are morpho-functionally heterogeneous, and the prevalence of a specific phenotype may influence the plaque fate. This heterogeneity has also been observed in monocyte-derived macrophages(MDMs), a model of macrophages infiltrating tissue. The study aims to assess oxidative stress status and Nrf2/HO-1 axis in MDM morphotypes obtained from healthy subjects and coronary artery disease (CAD) patients, in relation to coronary plaque features evaluated in vivo by optical coherence tomography (OCT). We found that MDMs of healthy subjects exhibited a lower oxidative stress status, lower Nrf2 and HO-1 levels as compared to CAD patients. High HO-1 levels in MDMs were associated with the presence of a higher macrophage content, a thinner fibrous cap, and a ruptured plaque with thrombus formation, detected by OCT analysis. These findings suggest the presence of a relationship between in vivo plaque characteristics and in vitro MDM profile, and may help to identify patients with rupture-prone coronary plaque.</p> <p> </p>
Activity of bacteriocins against Clostridioides difficile in a Simplified Human Intestinal Microbiome
Open the record for dataset details and reuse information.
Alzheimer’s disease neuroinflammatory risk genes can be targeted with RNase-H active antisense oligonucleotides in human microglia (TREM2 subset_GEO)
GEO Series GSE222332. Homo sapiens. 81 samples. Type: Expression profiling by array.
Genetic engineered primary human natural killer cells targeting TIGIT via CRISPR/Cas9 enhanced anti-tumor activity against GBM spheroids and 2D culture.
GEO Series GSE212941. Homo sapiens. 2 samples. Type: Expression profiling by array.
Dihydrofolate reductase metabolic activity controls neurogenic transitions in the developing human and mouse neocortex [ChIP-seq]
GEO Series GSE206407. Mus musculus. 6 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Selective time-dependent changes in activity- and cell-specific gene expression in human postmortem brain
GEO Series GSE153669. Homo sapiens. 7 samples. Type: Expression profiling by high throughput sequencing.
TCR signaling via NFATc1 constrains IL-15-induced NK-like activation of human memory CD8+ T cells [RNAseq_IONO_12H]
GEO Series GSE305712. Homo sapiens. 40 samples. Type: Expression profiling by high throughput sequencing.
Alzheimer’s disease neuroinflammatory risk genes can be targeted with RNase-H active antisense oligonucleotides in human microglia
GEO Series GSE222333. Homo sapiens. 189 samples. Type: Expression profiling by array.
Transcriptome comparison of monocytes, activated CD4 T cells, and activated CD8 T cells in healthy human peripheral blood
GEO Series GSE263462. Homo sapiens. 9 samples. Type: Expression profiling by high throughput sequencing.
Tie2 activation relieves lymphedema by improving lymphatic endothelial integrity [Human RNA-seq]
GEO Series GSE255848. Homo sapiens. 10 samples. Type: Expression profiling by high throughput sequencing.
mmWave Radar and RGB-D Camera Sensor Data for Human Activity Recognition(2)
<p>This is a supplementary dataset, which is linked to https://zenodo.org/record/7088054#.YyVF3ehBwQ8. The dataset is composed of corner radar point cloud data and front radar point cloud data collected from environments existing obstacles between volunteers and sensors. </p>
Replay-triggered Brain-wide Activation in Humans
<p>Main data and results of 'Replay-triggered Brain-wide Activation in Humans'.</p>
Bacillus Calmette–Guérin-induced human mast cell activation relies on IL-33 priming
<p>2 Video, supplementary material for submitted manuscript</p>
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.