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1,890 results for “Defects”

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geo24/100

Correction of splicing defect in compound heterozygous FRDA patient carrying FXN 165+5G>C point mutation.

GEO Series GSE262763. Homo sapiens. 1 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJul 2025View details →
geo24/100

Genome wide analysis of binding of Polyhomeotic and polymerization defective Polyhomeotic in Drosophila S2 cells

GEO Series GSE60686. Drosophila melanogaster. 10 samples. Type: Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing.

openGEO-OpenMar 2016View details →
geo24/100

DYSREGULATION OF THE m6A EPITRANSCRIPTOME AS A NEW MECHANISM INVOLVED IN HIPPOCAMPAL-DEPENDENT MEMORY DEFECTS IN HD MICE

GEO Series GSE175618. Mus musculus. 48 samples. Type: Other.

openGEO-OpenJul 2022View details →
geo24/100

Alternative splicing and gene expression defects in motorneurons derived from DM1 hiPSCs and MBNL knockouts hiPSCs generated by CRISPR/Cas9.

GEO Series GSE171988. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenApr 2023View details →
geo24/100

Defective minor spliceosomes induce SMA-associated phenotypes through sensitive intron-containing neural genes in Drosophila

GEO Series GSE138183. Drosophila melanogaster. 8 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenApr 2020View details →
geo24/100

MicroRNA 19a replacement partially rescues fin and cardiac defects in zebrafish model of Holt Oram syndrome [array]

GEO Series GSE69578. Danio rerio. 8 samples. Type: Expression profiling by array.

openGEO-OpenOct 2015View details →
geo24/100

Comparison of Transcription Profiles of M. smegmatis overexpressing wild type and phopshorylation defective PknK

GEO Series GSE180348. Mycolicibacterium smegmatis. 8 samples. Type: Expression profiling by array.

openGEO-OpenMar 2022View details →
geo24/100

High throughput sequencing identifies misregulated genes in the Drosophila Polypyrimidine Tract-binding protein (hephaestus) mutant defective in spermatogenesis

GEO Series GSE77706. Drosophila melanogaster. 2 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenFeb 2017View details →
geo24/100

Systemic RNA interference-defective (SID) genes modulate dopaminergic neurodegeneration in C. elegans

GEO Series GSE205118. Caenorhabditis elegans. 6 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenAug 2022View details →
geo24/100

RNAseq of circulating CD34+ cells derived from TCIRG1-defective patients

GEO Series GSE132889. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenApr 2020View details →
geo24/100

Defective Integrator activity shapes the transcriptome of patients with multiple sclerosis: patient data

GEO Series GSE249613. Homo sapiens. 26 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJul 2024View details →
geo24/100

LncRNA LIMp27 regulates the DNA damage response through p27 in p53-defective cancer cells

GEO Series GSE208711. Homo sapiens. 9 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenDec 2022View details →
geo24/100

Patient derived model of UBA5-associated encephalopathy identifies defects in neurodevelopment and highlights potential therapies

GEO Series GSE289906. Homo sapiens. 24 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenFeb 2025View details →
geo24/100

Proteogenomic characterization of developmental defects in the forebrain resulting from hyperactivated mTOR signaling

GEO Series GSE93325. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenSep 2017View details →
geo24/100

AntimiR blocking of miR-23b and -218 corrects myotonic dystrophy primary cell defects over a wide range of CTG repeat expansions.

GEO Series GSE237411. Homo sapiens. 33 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenMay 2024View details →
geo24/100

Regulation of constitutive and alternative splicing by PRMT5 reveals a role for Mdm4 pre-mRNA in sensing defects in the spliceosomal machinery (RNA-Seq)

GEO Series GSE45284. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenSep 2013View details →
geo24/100

Liver mRNA expression in 25 mice with or without genetic defects of mitochondrial fatty acid oxidation (Acadl and Acadvl knockout) using RNA sequencing

GEO Series GSE186613. Mus musculus. 25 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenOct 2024View details →
geo24/100

Dysregulation of MITF in the context of defective MC1R and RB1/p16/CDK4 leads to melanocyte transformation [microarray]

GEO Series GSE142012. Homo sapiens. 4 samples. Type: Expression profiling by array.

openGEO-OpenJul 2020View details →
geo24/100

Defective metabolic programming impairs early neuronal morphogenesis in neural cultures and an organoid model of Leigh syndrome

GEO Series GSE126360. Homo sapiens. 40 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJan 2021View details →
geo24/100

Recurrent 17q23.2 microdeletion flanked by segmental duplications associated with heart defects and limb abnormalities

GEO Series GSE19932. Homo sapiens. 7 samples. Type: Genome variation profiling by genome tiling array.

openGEO-OpenDec 2010View details →

ScienceDex guides

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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.

Compare curated datasets

Allen Brain Atlas

Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.

allen-brain-atlas
neuroscienceopenDocumentation, web resources, and API references are available online.
Last verified 2026-04-30Open record

Annotated Behaviour and Observability Dataset (ABODe)

ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.

abode-home-cage
behavioral-neuroscienceopenThe DataShare record exposes download links for annotations, documentation, license text, and the zipped per-snippet data directory.
Last verified 2026-04-30Open record

DANDI Archive for NWB datasets

DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.

dandi-nwb
electrophysiologyopenPublished Dandiset metadata and archive endpoints are available through the production DANDI API.
Last verified 2026-04-30Open record

International Brain Laboratory public data

The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.

ibl
behavioral-neuroscienceopenPublic sessions can be searched and loaded from the IBL public data server through ONE.
Last verified 2026-04-29Open record

OpenNeuro

OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.

openneuro
neuroscienceopenPublished datasets are available on demand over the internet.
Last verified 2026-04-29Open record