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1,017 results for “Antimicrobial”
Nasopharyngeal Carriage, Antimicrobial Resistance, and Serotype Distribution of Streptococcus pneumoniae in Children Under Five in Lebanon: Baseline Data Prior to PCV13 Introduction
<p>Dataset and R Code Script</p>
Data for publication "Selected Simple Natural Antimicrobial Terpenoids as Additives to Control Biodegradation of Polyhydroxy Butyrate"
<p><strong>Abstract</strong></p> <div>In this experimental research, different types of essential oils (EOs) were blended with polyhydroxybutyrate (PHB) to study the influence of these additives on PHB degradation. The blends were developed by incorporating three terpenoids at two concentrations (1 and 3%). The mineralization rate obtained from CO<sub>2</sub> released from each sample was the factor that defined biodegradation. Furthermore, scanning electron microscope (SEM), differential scanning calorimetry (DSC), and dynamic mechanical analysis (DMA) were used in this research. The biodegradation percentages of PHB blended with 3% of eucalyptol, limonene, and thymol after 226 days were reached 66.4%, 73.3%, and 76.9%, respectively, while the rate for pure PHB was 100% after 198 days, and SEM images proved these results. Mechanical analysis of the samples showed that eucalyptol had the highest resistance level, even before the burial test. The other additives showed excellent mechanical properties although they had less mechanical strength than pure PHB after extrusion. The samples’ mechanical properties improved due to their crystallinity and decreased glass transition temperature (Tg). DSC results showed that blending terpenoids caused a reduction in Tg, which is evident in the DMA results, and a negligible reduction in melting point (Tm).</div> <div> </div> <p>Data for publication contains: Scanning Electron Microscope (SEM), Differential Scanning Calorimetry (DSC), and Dynamic Mechanical Analysis (DMA) figures and images for samples</p> <p>Full publication can be found here: <em>https://zenodo.org/records/13785631</em></p>
Assessment of animal diseases caused by bacteria resistant to antimicrobials: Dogs and cats - Appendix B: Excel file with all data extracted
<p>Information on all the full-text studies that were assessed, including the reason for exclusion for those that were excluded at the full-text screening and the data extracted from the included studies, can be consulted here. </p> <p>The extensive literature review was carried out by the University of Copenhagen under the contract OC/EFSA/ALPHA/2020/02 – LOT 1 (https://ted.europa.eu/udl?uri=TED:NOTICE:457654-2020:TEXT:EN:HTML)</p>
Aquatic animal antimicrobial resistance trends dataset and R code
<p>First release of aquatic animal AMR R scripts and dataset accompanying "Twenty-year trends in antimicrobial resistance from aquaculture and fisheries in Asia" (doi: 10.1038/s41467-021-25655-8)</p>
Dataset for Examining the Antimicrobial Efficacy of Granulated Tetraacetylethylenediamine (TAED) Derived Peracetic Acid and Commercial Peracetic Acid in Urban Wastewaters
<p>The dataset used to generate figures in the manuscript, <em>Examining the Antimicrobial Efficacy of Granulated Tetraacetylethylenediamine (TAED) Derived Peracetic Acid and Commercial Peracetic Acid in Urban Wastewaters,</em><strong> </strong>submitted to Water Environment Research for publication. </p>
Assessment of animal diseases caused by bacteria resistant to antimicrobials: Horses - Appendix B: Excel file with all data extracted
<p>Information on all the full-text studies that were assessed, including the reason for exclusion for those that were excluded at the full-text screening and the data extracted from the included studies, can be consulted here. </p> <p>The extensive literature review was carried out by the University of Copenhagen under the contract OC/EFSA/ALPHA/2020/02 – LOT 1 (https://ted.europa.eu/udl?uri=TED:NOTICE:457654-2020:TEXT:EN:HTML)</p>
Investigating the cultural and contextual determinants of antimicrobial stewardship programmes across low-, middle- and high-income countries – a qualitative study
<p>An animation summarising the key findings from a qualitative study conducted as part of a PhD study across England, France, Norway, India and Burkina Faso investigating the influence of culture and team dynamics on the implementation of antimicrobial stewardship interventions. Fifty-four healthcare professionals across 24 hospitals, all of whom had a role in the implementation of antimicrobial stewardship were interviewed to investigate the challenges to implementing interventions across different healthcare settings. </p>
Green synthesis of ZnO nanoparticles using Cocos nucifera leaf extract: Characterization, antimicrobial, antioxidant, and photocatalytic activity
<p>Zinc oxide nanoparticles (ZnO NPs) have been successfully prepared using <em>Cocos nucifera</em> leaf extract and investigated with their antimicrobial, antioxidant, and photocatalytic activity. The structural, compositional, and morphological properties of the NPs were recorded and studied systematically to confirm the synthesis. The aqueous suspension of NPs showed a UV-Vis. absorption maxima of 370 nm indicating primarily its formation. The XRD analysis identified the NPs with hexagonal wurtzite structure with an average particle size of 16.6 nm. The FTIR analysis identified some biomolecules and functional groups in the leaf extract as responsible for the encapsulation and stabilization of ZnO NPs. The EDX analysis showed the desired elemental compositions in the material. A flower-shaped morphology of ZnO NPs was observed by SEM with a grain size of around 15 nm. The optical properties of the NPs were studied by UV-Vis spectroscopy and the bandgap was calculated as 3.37 eV. The Prepared ZnO NPs have demonstrated antimicrobial activity against <em>T. harzianum</em>, and <em>S. aureus</em> with a ZOI (zone of inhibition) of 14 and 10 mm, respectively. The photocatalytic behavior of ZnO NPs showed absorbance degradation at around 640 nm and discolored methylene blue dye after one hour with a degradation maximum of 84.29 %. Thus, the prepared ZnO NPs could be used potentially in antibiotic development, pharmaceutical industries, and as photocatalysts. </p>
Dataset for: Social dilemma in the excess use of antimicrobials incurring antimicrobial resistance
<p><span>This is the dataset for the study of "Social dilemma in the excess use of antimicrobials incurring antimicrobial resistance". </span></p> <p><span>The emergence of antimicrobial resistance (AMR) caused by the excess use of antimicrobials has come to be recognized as a global threat to public health. There is a 'tragedy of the commons' type social dilemma behind this excessive use of antimicrobials, which should be recognized by all stakeholders. To address this global threat, we thus surveyed eight countries/areas to determine whether people recognize this dilemma and showed that although more than half of the population pays little, if any, attention to it, almost 20% recognize this social dilemma, and 15–30% of those have a positive attitude toward solving that dilemma. We suspect that increasing individual awareness of this social dilemma contributes to decreasing the frequency of AMR emergencies.</span></p>
Data for HydrAMP - a deep generative model for antimicrobial peptide discovery
<ul> <li>data- training data for peptides < 25 AA (16.8 MB)</li> <li>models - checkpoints of HydrAMP, PepCVAE, and Basic models for every training epoch (466 MB)</li> <li>results - dumped generation results for every model. Required for running comparison notebooks (832 MB)</li> <li>wheels - custom TensorFlow packages (1 GB)</li> </ul> <p> </p>
Assessment of antimicrobial activity of melittin encapsulated in bicontinuous microemulsions prepared using renewable oils
<p>The objective of this study is to demonstrate that melittin, a well-studied antimicrobial peptide (AMP), can be solubilized in an active form in bicontinuous microemulsions (BMEs) that employ biocompatible oils. The systems investigated consisted of Winsor-III and -IV BME phases composed of Water/Aerosol-OT (AOT)/Polysorbate 85/isopropyl myristate and a Winsor-IV BME employing Polysorbate 80 and limonene. We found that melittin resided in an a-helix-rich configuration and was in an apolar environment for the AOT/Polysorbate 85 Winsor-III system, suggesting that melittin interacted with the surfactant monolayer and was in an active conformation. An apolar environment was also detected for melittin in the two Winsor-IV systems, but to a lesser extent than the Winsor-III system. Small-angle X-ray scattering analysis indicated that melittin at a concentration of 1.0 g/L<sub>aq</sub> in the aqueous subphase of the Winsor-IV systems led to the greatest impact on the BME structure (e.g., decrease of quasi-periodic repeat distance and correlation length and induction of interfacial fluidity). The antimicrobial activity of the Polysorbate 80 Winsor-IV system was evaluated against several bacteria prominent in chronic wounds and surgical site infections (SSIs). Melittin-free BMEs inhibited the growth of all tested bacteria due to its oil, limonene, while the inclusion of 1.0 g/L<sub>aq</sub> of melittin in the BMEs enhanced the activity against several bacteria. A further increase of melittin concentration in the BMEs had no effect. These results demonstrate the potential utility of BMEs as a delivery platform for AMPs and other hydrophilic and lipophilic drugs to inhibit antibiotic-resistant microorganisms in chronic wounds and SSIs.</p>
Hybrid AgNPs/eggshell calcium carbonate particles and their antimicrobial efficiency
<p>In this study, hybrid particles of AgNPs<span>-</span>loaded eggshell calcium carbonate <span>(</span>AgNPs<span>/</span>eCaCO<sub>3</sub><span>)</span> were prepared<em> in situ</em> by precipitating the eggshell in the presence of freshly prepared AgNPs with a particle size of 10<span>-</span>30 nm<span>. </span>The hybrid particles were comparatively precipitated<em> in situ</em> at 25 °C and 35 °C using poly <span>(</span>sodium 4<span>-</span>styrenesulphonate<span>) </span>as a polyelectrolyte<span>. </span>The AgNPs<span>/</span>eCaCO<sub>3</sub> particles prepared at 25 °C had a spherical morphology with a mean diameter of 3<span>.</span>56 mm, and BET surface area of 85.08 m<sup>2</sup>/g. On the other hand, the particles prepared at 35 °C had a broader size distribution with a mean diameter of 3<span>.</span>19 mm, and a BET surface area of 79.25 m<sup>2</sup>/g<span>.</span> AgNPs<span>-</span>loaded commercial calcium carbonate particles<span> (</span>AgNPs<span>/</span>e=CaCO<sub>3</sub><span>) </span>comparatively prepared at 35 °C were perfectly spherical with a mean diameter of 5<span>.</span>61 mm<span>. </span>At preparing temperature of 25 °C, the hybrid particles contain AgNPs of 0<span>.</span>78 wt<span>% </span>for AgNPs<span>/</span>eCaCO<sub>3</sub> and 3<span>.</span>20 wt<span>% </span>for AgNPs<span>/</span>CaCO<sub>3</sub><span>. </span>The AgNPs<span>/</span>eCaCO<sub>3</sub> and AgNPs<span>/</span>CaCO<sub>3</sub> particles exhibited the same efficiency against bacteria extracted from beef with an average inhibition zone diameter of 7–10 mm according to the modified Kirby<span>–</span>Bauer disc diffusion assay depending on their concentration and beef source<span>. </span>Freshly prepared silver colloids showed comparatively poorer antimicrobial efficiency with an inhibition zone diameter around 7 mm<span>. </span></p>
Antimicrobial resistance monitoring results complementing the European Union Summary Report on Antimicrobial Resistance in zoonotic and indicator bacteria from humans, animals and food in 2020/2021 – Portugal
<p>This dataset contains AMR monitoring results in animals and food at the isolate level pursuant to Article 9 of Directive 2003/99/EC and to Annex, part B, of Commission implementing Decision (EU) 2020/1729. In addition, the dataset includes any other results from isolates than the ones mentioned in the Commission implementing Decision (EU) 2020/172. The quantitative minimum inhibitory concentration (MIC) data from dilution methods are included.</p> <p>Reporting authorities contributing to 2021 AMR data collection: Instituto Nacional de Investigação Agrária e Veterinária</p>
Antimicrobial resistance monitoring results complementing the European Union Summary Report on Antimicrobial Resistance in zoonotic and indicator bacteria from humans, animals and food in 2020/2021 – Sweden
<p>This dataset contains AMR monitoring results in animals and food at the isolate level pursuant to Article 9 of Directive 2003/99/EC and to Annex, part B, of Commission implementing Decision (EU) 2020/1729. In addition, the dataset includes any other results from isolates than the ones mentioned in the Commission implementing Decision (EU) 2020/172. The quantitative minimum inhibitory concentration (MIC) data from dilution methods, as well as the voluntary reporting of and Whole Genome Sequencing (WGS) data are included.</p> <p>Reporting authorities contributing to 2021 AMR data collection: National Veterinary Institute, Swedish Zoonosis Centre</p>
Antimicrobial resistance monitoring results complementing the European Union Summary Report on Antimicrobial Resistance in zoonotic and indicator bacteria from humans, animals and food in 2020/2021 – Poland
<p>This dataset contains AMR monitoring results in animals and food at the isolate level pursuant to Article 9 of Directive 2003/99/EC and to Annex, part B, of Commission implementing Decision (EU) 2020/1729. In addition, the dataset includes any other results from isolates than the ones mentioned in the Commission implementing Decision (EU) 2020/172. The quantitative minimum inhibitory concentration (MIC) data from dilution methods, as well as the voluntary reporting of and Whole Genome Sequencing (WGS) data are included.</p> <p>Reporting authorities contributing to 2021 AMR data collection: National Veterinary Research Institute</p>
2021aggregated dataset submitted on the negative results for extended-spectrum b-lactamase(ESBL) and the carbapenemase-producers - complementing the European Union Summary Report on Antimicrobial Resistance in zoonotic and indicator bacteria from humans, animals and food 2020/2021
<p>Data provided by the Member States on the 2021 on the negative results for extended-spectrum b-lactamase(ESBL) and the carbapenemase-producers - complementing the European Union Summary Report on Antimicrobial Resistance in zoonotic and indicator bacteria from humans, animals and food 2020/2021.</p>
Antimicrobial resistance monitoring results complementing the European Union Summary Report on Antimicrobial Resistance in zoonotic and indicator bacteria from humans, animals and food in 2020/2021 – The Netherlands
<p>This dataset contains AMR monitoring results in animals and food at the isolate level pursuant to Article 9 of Directive 2003/99/EC and to Annex, part B, of Commission implementing Decision (EU) 2020/1729. In addition, the dataset includes any other results from isolates than the ones mentioned in the Commission implementing Decision (EU) 2020/172. The quantitative minimum inhibitory concentration (MIC) data from dilution methods are included.</p> <p>Reporting authorities contributing to 2021 AMR data collection: Netherlands Food and Consumer Product Safety Authority</p>
Antimicrobial resistance monitoring results complementing the European Union Summary Report on Antimicrobial Resistance in zoonotic and indicator bacteria from humans, animals and food in 2020/2021 – Slovenia
<p>This dataset contains AMR monitoring results in animals and food at the isolate level pursuant to Article 9 of Directive 2003/99/EC and to Annex, part B, of Commission implementing Decision (EU) 2020/1729. In addition, the dataset includes any other results from isolates than the ones mentioned in the Commission implementing Decision (EU) 2020/172. The quantitative minimum inhibitory concentration (MIC) data from dilution methods are included.</p> <p>Reporting authorities contributing to 2021 AMR data collection: Ministry for Agriculture, Forestry and Food</p>
2021 MRSA Prevalence - complementing the European Union Summary Report on Antimicrobial Resistance in zoonotic and indicator bacteria from humans, animals and food 2020/2021
<p>Data provided by the Member States on the 2021 MRSA Prevalence - complementing the European Union Summary Report on Antimicrobial Resistance in zoonotic and indicator bacteria from humans, animals and food 2020/2021.</p>
Antimicrobial resistance monitoring results complementing the European Union Summary Report on Antimicrobial Resistance in zoonotic and indicator bacteria from humans, animals and food in 2020/2021 – Slovakia
<p>This dataset contains AMR monitoring results in animals and food at the isolate level pursuant to Article 9 of Directive 2003/99/EC and to Annex, part B, of Commission implementing Decision (EU) 2020/1729. In addition, the dataset includes any other results from isolates than the ones mentioned in the Commission implementing Decision (EU) 2020/172. The quantitative minimum inhibitory concentration (MIC) data from dilution methods are included.</p> <p>Reporting authorities contributing to 2021 AMR data collection: State Veterinary and Food Institute</p>
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
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International Brain Laboratory public data
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OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.