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291
datasets available to search
ShareScore release 0.9.0
Dataset results
291 results for “C57BL/6J”
Development and Characterization of Syngeneic Orthotopic Transplant Models of Obesity-Responsive Triple-Negative Breast Cancer in C57BL/6J Mice (in vivo)
GEO Series GSE272328. Mus musculus. 24 samples. Type: Expression profiling by array.
Next Generation Sequencing Facilitates Quantitative Analysis of C57BL/6J mice Incisor Transcriptomes at single cell level.
GEO Series GSE154278. Mus musculus. 2 samples. Type: Expression profiling by high throughput sequencing.
A multicentre study on spontaneous in-cage activity and micro-environmental conditions of IVC housed C57BL/6J mice during consecutive cycles of bi-weekly cage change
<p>Mice respond to a cage change (CC) with altered activity, disrupted sleep and increased anxiety. A bi-weekly cage change is, therefore, preferred over a shorter CC interval and is currently the prevailing routine for Individually ventilated cages (IVCs). However, the build-up of ammonia (NH3) during this period is a potential threat to the animal health and the literature holds conflicting reports leaving this issue unresolved. We have therefor examined longitudinally in-cage activity, animal health and the build-up of ammonia across the cage floor with female and male C57BL/6 mice housed four per IVC changed every other week. We used a multicentre design with a standardised husbandry enabling us to tease-out features that replicated across sites from those that were site-specific.</p> <p>CC induce a marked increase in activity, especially during daytime (~50%) when the animals rest. A reduction in density from four to two mice did not alter this response. This burst was followed by a gradual decrease till the next cage change. Female but not male mice preferred to have the latrine in the front of the cage. Male mice allocate more of the activity to the latrine free part of the cage floor already the day after a CC. A behaviour that progressed through the CC cycle but was not impacted by the type of bedding used. Reducing housing density to two mice abolished this behaviour. Female mice used the entire cage floor the first week while during the second week activity in the latrine area decreased.</p> <p>Measurement of NH3 ppm across the cage floor revealed x3 higher values for the latrine area compared with the opposite area. NH3 ppm increases from 0-1 ppm to reach ≤25 ppm in the latrine free area and 50-100 ppm in the latrine area at the end of a cycle. As expected in-cage bacterial load covaried with in-cage NH3 ppm.</p> <p>Histopathological analysis revealed no changes to the upper airways covarying with recorded NH3 ppm or bacterial load. We conclude that housing of four (or equivalent biomass) C57BL/6J mice for 10 weeks under the described conditions does not cause any overt discomfort to the animals.</p>
Alcohol and fear conditioning produce strain-specific changes in the dorsal hippocampal transcriptome of adolescent C57BL/6J and DBA/2J mice
GEO Series GSE269129. Mus musculus. 63 samples. Type: Expression profiling by high throughput sequencing.
Gene expression profiles at the single cell level of cochlear cells from C57BL/6J mice at both embryonic day 15 and postnatal day 7
GEO Series GSE217727. Mus musculus. 3 samples. Type: Expression profiling by high throughput sequencing.
6 small intestinal macrophage subsets (CD4–Tim4–CD163–, CD4+Tim4–CD163–, CD4+Tim4+CD163–, CD4–Tim4–CD163+, CD4+Tim4–CD163+, CD4+Tim4+CD163+ ) from adult male C57BL/6J mice
GEO Series GSE232645. Mus musculus. 20 samples. Type: Expression profiling by high throughput sequencing.
Gene expression profiling in left cardiac ventricles of C57Bl/6J and C57Bl/6N male mice treated for 48 h with angiotensin II 500 ng/kg/min.
GEO Series GSE53269. Mus musculus. 14 samples. Type: Expression profiling by array.
RNA-Seq of eye tissues from C57BL/6J background mice at 1.5 h and 9.0 h after light onset
GEO Series GSE48974. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
A multicentre study on spontaneous in-cage activity and micro-environmental conditions of IVC housed C57BL/6J mice during consecutive cycles of bi-weekly cage change
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Chronic Arsenic Exposure Impairs Adaptive Thermogenesis in Male C57BL/6J Mice
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Expression profiles of TIS21/BTG2/PC3 gene knockout in liver of C57BL/6J mice in response to starvation
GEO Series GSE105772. Mus musculus. 8 samples. Type: Expression profiling by array.
Cardiac left ventricles of 12 week-old male C57BL/6J and C57BL/6J-chrY<A/J/NaJ> mice
GEO Series GSE15354. Mus musculus. 16 samples. Type: Expression profiling by array.
RNA-seq and anti-LMO2 ChIP-seq data in primary T cells in different stages from LMO2 over-expressing C57BL/6J transgenic mice
GEO Series GSE186943. Mus musculus. 46 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Gene expression analysis at three different stages of myelination in dorsal root ganglion (DRG) explant cultures isolated from E13.5 C57BL/6J mouse embryos.
GEO Series GSE60345. Mus musculus. 18 samples. Type: Expression profiling by array.
Effect of 4.25% PD fluid treatment on the peritoneum of MR1+/+ C57BL/6J and MR1-/- C57BL/6J mice
GEO Series GSE279547. Mus musculus. 10 samples. Type: Expression profiling by high throughput sequencing.
Development and Characterization of Syngeneic Orthotopic Transplant Models of Obesity-Responsive Triple-Negative Breast Cancer in C57BL/6J Mice (in vitro)
GEO Series GSE272327. Mus musculus. 12 samples. Type: Expression profiling by array.
Mouse liver H3K27ac histone marks in male and female mouse liver for two mouse strains: C57BL/6J and CAST/EiJ.
GEO Series GSE130909. Mus musculus. 24 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
External factors inducing metabolic adaptations in white adipose tissue in wildtype C57BL/6J mice housed at thermoneutrality.
GEO Series GSE53805. Mus musculus. 30 samples. Type: Expression profiling by array.
Comparison of circRNA expression profile among the livers of C57BL/6J control mice, high fat diet (HFD) mice and metformin treated mice
GEO Series GSE94841. Mus musculus. 9 samples. Type: Non-coding RNA profiling by array.
CUT&Tag (H3K27me3) in MGE, CGE, LGE and cortical regions from mouse (C57BL/6J) embryonic forebrain
GEO Series GSE201488. Mus musculus. 11 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.