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172
datasets available to search
ShareScore release 0.9.0
Dataset results
172 results for “Engineering studies”
Visualization Engineering Platform for TCM Pulse Diagnosis - Pulse Diagnosis Based on Federated Learning to Diagnose Slippery and Choppy and Other Pulses Waveform Image Features to Assist in the Study
ClinicalTrials.gov study NCT05630248. IPD Sharing: NO. Countries: 1. Publications: 0.
Safety and Efficacy Study of Autologous Engineered Skin Substitute to Treat Partial- and Full-Thickness Burn Wounds
ClinicalTrials.gov study NCT01655407. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
Safety and Feasibility Study of Autologous Engineered Urethral Constructs for the Treatment of Strictures
ClinicalTrials.gov study NCT03258658. IPD Sharing: NO. Countries: 1. Publications: 0.
The Heidelberg Engineering ANTERION Anterior Segment Cornea and IOL Precision and Agreement Study
ClinicalTrials.gov study NCT04130490. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Tissue Engineering Microtia Auricular Reconstruction: in Vitro and in Vivo Studies
ClinicalTrials.gov study NCT00958802. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Phase I Study of Autologous CD8+ and CD4+ Engineered T Cell Receptor T Cells in Subjects With Advanced or Metastatic Solid Tumor
ClinicalTrials.gov study NCT06105021. IPD Sharing: NO. Countries: 1. Publications: 0.
A Phase 1/2 Study of KSQ-001EX, Autologous Tumor Infiltrating Lymphocytes Engineered to Inactivate the SOCS1 Gene, in Patients With Select Advanced Solid Tumors
ClinicalTrials.gov study NCT06237881. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Study 102: Multiple Ascending Dose Study of ALLN-346 (Engineered Urate Oxidase)
ClinicalTrials.gov study NCT04829435. IPD Sharing: NO. Countries: 1. Publications: 0.
The Heidelberg Engineering BI US Evaluation Study
ClinicalTrials.gov study NCT03578302. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Study Assessing the Feasibility, Safety and Efficacy of Genetically Engineered Glucocorticoid Receptor Knock Out Virus Specific CTL Lines for Viral Infections in Immunosuppressed Cancer Patients
ClinicalTrials.gov study NCT05101213. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Phase I/II Study of Engineered T Cell Receptor-Modified NK Cells Targeting PRAME in Conjunction With Lymphodepleting Chemotherapy for the Management of Relapse/Refractory Myeloid Malignancies
ClinicalTrials.gov study NCT06383572. IPD Sharing: Not stated. Countries: 1. Publications: 0.
A Study to Assess the Safety, Tolerability and Potential Efficacy of a Tracheal Replacement Consisting of a Tissue-engineered Tracheal Scaffold With Seeded Mesenchymal Cells
ClinicalTrials.gov study NCT02949414. IPD Sharing: YES. Countries: 1. Publications: 0.
Phase 1 Dose Escalation and Expansion Study of PRAME T Cell Receptor (TCR) Engineered NK Cells in Participants With Recurrent and/or Refractory Melanoma (PRAMETIME-Mel)
ClinicalTrials.gov study NCT06660420. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Personalized TCR-T: Study of Adoptively Transferred T-cell Receptor Gene-engineered T Cells (TCR-T)
ClinicalTrials.gov study NCT05349890. IPD Sharing: NO. Countries: 1. Publications: 0.
Safety Study of Acellular Tissue Engineered Vessel for Coronary Artery Bypass
ClinicalTrials.gov study NCT07078370. IPD Sharing: NO. Countries: 1. Publications: 0.
Flipped Classroom in Software Engineering: A Systematic Mapping Study
<p>Vídeo (backup) para apresentação de contingência</p>
Images used in 3D-engineered scaffolds to study patient-derived glioma cells
<p>Images used in the analysis of the research work " 3D-engineered scaffolds to study microtubes and localization of epidermal growth factor receptor in patient-derived glioma cells".</p> <p>Images can be available upon request. Please contact: a.accardo@tudelft or p.french@erasmusmc.nl</p>
Immune responses to the in vitro LPS assault engineered in the spaceflight multi-omics study
Microgravity alters the immune response to in vitro LPS assault engineered in spaceflight: A multi-omics study Microgravity can facilitate creation of a potent environment for opportunistic infection by augmenting virulence and suppressing the host defense. Presumably extraterrestrial infection may trigger potentially novel bionetworks different from the terrestrial equivalent which could only be probed by investigating the host-pathogen relationship with minimum terrestrial bias. Towards this objective we strategically engineered a cell culture module equipped with a feedback controlled semi-automated platform to expose human endothelial cells to lipopolysaccharide (LPS). The assay was carried out in the STS-135 space shuttle and a concurrent ground study constituted the baseline. Transcriptomic investigation revealed an immune blunting in microgravity; Lbp MyD88 and MD-2 failed to encode proteins responsible for early LPS uptake. Longer exposure results implied that there was a delayed response potentially ineffectual in preventing pathogens from opportunistically modulating the infection network. Lack of recruitment of growth factors and a debilitated apoptosome supported this potential explanation. Certain cytokines such as IL-6 and IL-8 surged in response to LPS insult in microgravity. Contrasting expressions of B2M TIMP-1 and VEGRs suggested impaired pro-survival adaptation and healing mechanisms. The susceptibility of oxidative stress and immune regulation to microgravity compelled further investigation of the respective microRNA modulators such as miR-200a and miR-146b. These miRNAs were expressed differently in response to LPS assaults in different gravitational limits. In conclusion despite a serious drawback attributed to the small sample size we delineated some of the important aspects of the extraterrestrial etiology; more comprehensive follow up studies are warranted. Present study though compromised by the small sample size was able to shade lights on several aspects of immunological responses to the endotoxic assault mediated by uG. Implementing the host-pathogen interactions in the spaceflight and subsequently lysing the cells onboard presented the critical distinguishing features of the present study from the past reports. We identified the CCM of Tissue Genesis Inc. HI as the suitable hardware system to carry out the experiment in the spaceflight. CCM is an automated feedback controlled module that can concurrently support 24 bioreactors following protocols exclusively programmed for individual bioreactor. For this experiment we use samples EA41 EA 47 EA45 and EA155 that were exposed to LPS for 4 hours. Samples EA123 EA165 EA127 EA126 were exposed to LPS for 8Hrs. Samples EA33 EA 125 EA79 and EA 39 were controls in this experiment.
Single cell RNA sequencing to study the in vivo behaviour of allogeneic HSC-derived MCAR-engineered NKT cells
GEO Series GSE270820. Homo sapiens. 30 samples. Type: Expression profiling by high throughput sequencing.
Studying heterogeneity in embryonic stem cells using the approach of search-engine
GEO Series GSE192644. Mus musculus. 190 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.