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133
datasets available to search
ShareScore release 0.9.0
Dataset results
133 results for “Genetic Engineering”
Advancing the genetic engineering toolbox by combining AsCas12a knock-in mice with ultra-compact screening
GEO Series GSE285778. Mus musculus. 86 samples. Type: Other.
Modeling Malignant Bone Disease Using Microgravity Bioreactors, Genetically Engineered Cell Lines, Patient-Derived Tumor Xenografts and Stem Cells
GEO Series GSE118107. Homo sapiens. 12 samples. Type: Expression profiling by array.
Transcriptome response of mouse mammary gland from age 12 to 30 months of age in Esr1 and CYP19A1 genetically engineered mouse models of breast cancer risk in the presence and absence of transgene ind
GEO Series GSE201767. Mus musculus. 48 samples. Type: Expression profiling by high throughput sequencing.
Genetically engineered hybridized OMVs for treatment of implant-associated infections and relapse prevention through host immunomodulation
GEO Series GSE281508. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Transcriptome response to anti-hormonals in Esr1 and CYP19A1 genetically engineered mouse models of breast cancer risk during reproductive senescence
GEO Series GSE201326. Mus musculus. 24 samples. Type: Expression profiling by high throughput sequencing; Non-coding RNA profiling by high throughput sequencing.
An evolved AAV variant enables efficient genetic engineering of murine T cells
GEO Series GSE216819. Mus musculus. 10 samples. Type: Other.
Changes in Physiology of Burley Tobacco Plants Genetically Engineered to Express a Functional NtEGY2 Gene
GEO Series GSE236277. Nicotiana tabacum. 12 samples. Type: Expression profiling by high throughput sequencing.
ChIP-sequencing of high grade glioma (HGG) mouse cells encoding for H3.3-G34R vs H3.3-WT histones, derived from a Sleeping beauty based-genetically engineered mouse model.
GEO Series GSE161503. Mus musculus. 36 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Genetically Engineered Mouse Models Unveil Mechanisms and Therapeutic Strategies for GMPPB-Associated Dystroglycanopathy II
GEO Series GSE268450. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Genetically Engineered Mouse Models Unveil Mechanisms and Therapeutic Strategies for GMPPB-Associated Dystroglycanopathy I
GEO Series GSE268448. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.
Sequencing of canine and genetically-engineered mouse models for endotype identification of embryonal rhabdomyosarcoma
Here, we report using RNA sequencing isolated from frozen tumor samples from genetically-engineered mouse models and canine samples, as well as a preserved mouse cell culture to determine endotypes, or subtypes with distinct pathobiological mechanisms, of embryonal rhabdomyosarcoma (ERMS) and nonrhabdomyosarcoma soft tissue sarcomas (NRSTS). With an unsupervised clustering approach of DNA and RNA sequencing from mouse models, canine samples, patient-derived xenograft models, and human samples we have found several major endotypes with a wide range of putative driver mutations. This study aims to define each of the several pathological mechanisms driving tumor maintenance in these tumors in order to identify effective targeted treatments for individual patients.
Single Patient Protocol: A Phase II Study Using the Administration of Autologous T-Cells Genetically Engineered to Express T-Cell Receptors Reactive Against Mutated Neoantigens in a Patient With Metas
ClinicalTrials.gov study NCT04135092. IPD Sharing: Not stated. Countries: 0. Publications: 0.
Genetic engineered primary human natural killer cells targeting TIGIT via CRISPR/Cas9 enhanced anti-tumor activity against GBM spheroids and 2D culture.
GEO Series GSE212941. Homo sapiens. 2 samples. Type: Expression profiling by array.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.