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341 results for “Neurodegeneration”

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geo24/100

Interferon-induced immunoproteasomes disturb neuronal metabolism and drive neurodegeneration in multiple sclerosis [RNA_Seq2_IFNG]

GEO Series GSE279706. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJul 2025View details →
geo24/100

Low molecular weight polysialic acid prevents lipopolysaccharide-induced inflammatory dopaminergic neurodegeneration in humanized SIGLEC11 transgenic mice

GEO Series GSE169637. Mus musculus. 48 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenDec 2021View details →
geo24/100

Deletion of Gba in neurons, but not microglia, causes neurodegeneration in a Gaucher mouse model

GEO Series GSE247436. Mus musculus. 32 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenOct 2024View details →
geo24/100

Enterovirus-A71 Preferentially Infects and Replicates in Human Motor Neurons, Inducing Neurodegeneration by Ferroptosis

GEO Series GSE261751. Homo sapiens. 2 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenAug 2024View details →
geo24/100

CD4+ T cells contribute to neurodegeneration in Lewy body dementia [CSF_and_PBMCs_Healthy and LBD]

GEO Series GSE141578. Homo sapiens. 35 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenSep 2021View details →
geo24/100

Chronic intermittent hypoxia inhibits the revascularization of the ischemic retina and aggravates neurodegeneration and neovascularization

GEO Series GSE268420. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenMar 2025View details →
geo24/100

The NR4A2/VGF pathway fuels inflammation-induced neurodegeneration via promoting neuronal glycolysis

GEO Series GSE247078. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJul 2024View details →
geo24/100

PRC2 controls adult neuron identity and protects neurons against neurodegeneration

GEO Series GSE84245. Mus musculus. 28 samples. Type: Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by array.

openGEO-OpenJul 2016View details →
geo24/100

Defective Mitophagy in XPA via PARP1 activation and NAD+/SIRT1-depletion: Implications for neurodegeneration (mouse)

GEO Series GSE55485. Mus musculus. 12 samples. Type: Expression profiling by array.

openGEO-OpenJun 2015View details →
geo24/100

Macrophage-induced enteric neurodegeneration leads to motility impairment during gut inflammation

GEO Series GSE263125. Mus musculus; Homo sapiens. 23 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenDec 2024View details →
geo24/100

Partial inhibition of mitochondrial complex I attenuates neurodegeneration and restores energy homeostasis and synaptic function in a symptomatic Alzheimer’s mouse model

GEO Series GSE149248. Mus musculus. 14 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenOct 2020View details →
geo24/100

Neuronal DNA double-strand breaks lead to genome structural variations and 3D genome disruption in neurodegeneration

GEO Series GSE227445. Mus musculus. 35 samples. Type: Other.

openGEO-OpenSep 2023View details →
geo24/100

Expression of human C9ORF72 hexanucleotide expansion reproduces RNA foci and dipeptide repeat proteins but not neurodegeneration in BAC transgenic mice

GEO Series GSE74973. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenNov 2015View details →
geo24/100

TREM2 shapes myeloid cell activations in trauma- and autoimmune-mediated neurodegeneration

GEO Series GSE198852. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJun 2023View details →
geo24/100

GGC repeat expansion within NOTCH2NLC causes behavioral deficits and neurodegeneration through misregulated alternative splicing

GEO Series GSE182878. Homo sapiens; Mus musculus. 25 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJan 2023View details →
geo24/100

Arf1-deficiency-induced neuronal surplus fatty acid synthesis evokes neurodegeneration through mtDNA releasing and inflammatory activating in microglia

GEO Series GSE273284. Mus musculus. 9 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenApr 2025View details →
geo24/100

Ldlr-/-.Leiden mice develop neurodegeneration, age-dependent astrogliosis and obesity-induced changes in microglia immunophenotype which are partly reversed by complement component 5 neutralizing anti

GEO Series GSE234425. Mus musculus. 46 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJun 2023View details →
geo24/100

Motor dysfunction and neurodegeneration in a C9orf72 mouse line expressing poly-PR

GEO Series GSE132108. Mus musculus. 24 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJun 2019View details →
geo24/100

Transcriptional profiling of microglia in the injured brain reveals distinct molecular features underlying neurodegeneration

GEO Series GSE163691. Mus musculus. 32 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenFeb 2021View details →
geo24/100

NMNAT2 Is Downregulated in Glaucomatous RGCs and RGC-Specific Gene Therapy with NMNAT2 Overexpression Rescues Glaucomatous Neurodegeneration and Visual Function

GEO Series GSE182483. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenAug 2021View details →

ScienceDex guides

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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.

Compare curated datasets

Allen Brain Atlas

Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.

allen-brain-atlas
neuroscienceopenDocumentation, web resources, and API references are available online.
Last verified 2026-04-30Open record

Annotated Behaviour and Observability Dataset (ABODe)

ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.

abode-home-cage
behavioral-neuroscienceopenThe DataShare record exposes download links for annotations, documentation, license text, and the zipped per-snippet data directory.
Last verified 2026-04-30Open record

DANDI Archive for NWB datasets

DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.

dandi-nwb
electrophysiologyopenPublished Dandiset metadata and archive endpoints are available through the production DANDI API.
Last verified 2026-04-30Open record

International Brain Laboratory public data

The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.

ibl
behavioral-neuroscienceopenPublic sessions can be searched and loaded from the IBL public data server through ONE.
Last verified 2026-04-29Open record

OpenNeuro

OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.

openneuro
neuroscienceopenPublished datasets are available on demand over the internet.
Last verified 2026-04-29Open record