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293
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ShareScore release 0.7.1
Dataset results
293 results for “Phase Separation”
Coactivator condensation at super-enhancers links phase separation and gene control (RNA-Seq)
GEO Series GSE112807. Mus musculus. 2 samples. Type: Expression profiling by high throughput sequencing.
Images Dataset for the Work of Phase Separation-based Antiviral Decoy Particles as Basis for Programmable Broad-spectrum Therapeutics
<p>Images dataset for the work of Phase Separation-based Antiviral Decoy Particles as Basis for Programmable Broad-spectrum Therapeutics.</p> <p>Used for the code cited in the paper.</p>
Data from: Stoichiometry controls activity of phase-separated clusters of actin signaling proteins
Biomolecular condensates concentrate macromolecules into foci without a surrounding membrane. Many condensates appear to form through multivalent interactions that drive liquid-liquid phase separation (LLPS). LLPS increases the specific activity of actin regulatory proteins toward actin assembly by the Arp2/3 complex. We show that this increase occurs because LLPS of the Nephrin–Nck–N-WASP signaling pathway on lipid bilayers increases membrane dwell time of N-WASP and Arp2/3 complex, consequently increasing actin assembly. Dwell time varies with relative stoichiometry of the signaling proteins in the phase-separated clusters, rendering N-WASP and Arp2/3 activity stoichiometry dependent. This mechanism of controlling protein activity is enabled by the stoichiometrically undefined nature of biomolecular condensates. Such regulation should be a general feature of signaling systems that assemble through multivalent interactions and drive nonequilibrium outputs.
A Phase I Study to Evaluate the PK and PD Profiles of GZR102 Injection Versus GZR4 Injection and GZR18 Injection Given Separately in Chinese Adult Overweight Subjects
ClinicalTrials.gov study NCT06974487. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Topoisomerase 1 Nicking-dependent HP1gamma Engagement Mediates Acute Activation of Phase-separated Enhancers
GEO Series GSE135808. Homo sapiens; Mus musculus. 167 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
The intrinsically disordered region of SPIN1 regulates its function by phase separation.
GEO Series GSE215400. Homo sapiens. 15 samples. Type: Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing.
Arabidopsis AGO1 N-terminal Poly-Q domain promotes phase separation and association with stress granules during heat stress [nanoPARE]
GEO Series GSE239834. Arabidopsis thaliana. 9 samples. Type: Expression profiling by high throughput sequencing.
Data from: Mechanics of composite hydrogels approaching phase separation
Open the record for dataset details and reuse information.
Data from: Stoichiometry controls activity of phase-separated clusters of actin signaling proteins
Open the record for dataset details and reuse information.
Nuclear mRNA processing domain formed by PABPN1 - mRNA phase separation is essential for the growth of oocytes and female reproduction
GEO Series GSE179406. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Long non-coding RNA AFAP1-AS1 promotes alternative splicing of AXIN2 by facilitating SRSFs phase separation to induce drug resistance in lung adenocarcinoma
GEO Series GSE300659. Homo sapiens. 8 samples. Type: Expression profiling by high throughput sequencing.
Phase separation of phospho-HDAC6 drives aberrant chromatin architecture in triple-negative breast cancer [ChIP-seq, Cut&Tag, ATAC-seq]
GEO Series GSE253743. Homo sapiens. 41 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Arabidopsis AGO1 N-terminal Poly-Q domain promotes phase separation and association with stress granules during heat stress [miRNA-seq]
GEO Series GSE239836. Arabidopsis thaliana. 18 samples. Type: Non-coding RNA profiling by high throughput sequencing.
DDX18 coordinates nucleolus phase separation and nuclear organization to control the pluripotency of human embryonic stem cells
GEO Series GSE182855. Homo sapiens. 2 samples. Type: Other.
The Nuclear Matrix Protein SAFB Cooperates with Major Satellite RNAs to Stabilize Heterochromatin Architecture Partially through Phase Separation [RNA-seq]
GEO Series GSE141294. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.
CAF-1 promotes HIV-1 latency by leading the formation of phase-separated suppressive nuclear bodies.
GEO Series GSE166337. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Filamentation and Biofilm Formation are Regulated by the Phase-Separation Capacity of Network Transcription Factors in Candida albicans
GEO Series GSE245897. Candida albicans. 12 samples. Type: Expression profiling by high throughput sequencing.
Disrupting YAP phase separation attenuates the development of primary liver cancer in animal models
GEO Series GSE277433. Mus musculus. 16 samples. Type: Expression profiling by high throughput sequencing.
The Nuclear Matrix Protein SAFB Cooperates with Major Satellite RNAs to Stabilize Heterochromatin Architecture Partially through Phase Separation
GEO Series GSE125037. Mus musculus. 28 samples. Type: Expression profiling by high throughput sequencing.
Bombyx Vasa sequesters transposon mRNAs in nuage via phase separation requiring RNA binding and self-association [RIP-Seq]
GEO Series GSE213914. Bombyx mori. 4 samples. Type: Expression profiling by high throughput sequencing.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.