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246
datasets available to search
ShareScore release 0.9.0
Dataset results
246 results for “ROS”
NOX1 is essential for TNFα-induced intestinal epithelial ROS secretion and inhibits M cell differentiation [RNA-seq organoid]
GEO Series GSE202777. Homo sapiens. 14 samples. Type: Expression profiling by high throughput sequencing.
Hyperosmotic stress induces 2-cell-like cells through ROS and ATR signaling
GEO Series GSE231475. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.
ASC-J9 blocks STAT3 signaling, cell proliferation, collagen synthesis, inflammation, and ROS generation in keloid fibroblasts
GEO Series GSE198095. Homo sapiens. 4 samples. Type: Expression profiling by high throughput sequencing.
Beyond the polymerase-gamma theory: Respiratory chain inhibition and production of ROS as modes of NRTI induced mitochondrial toxicity
GEO Series GSE100482. Caenorhabditis elegans. 30 samples. Type: Expression profiling by high throughput sequencing.
The circular RNA circ_ATP8B regulates ROS production and antiviral immunity [circRNA-Seq]
GEO Series GSE248666. Drosophila melanogaster. 2 samples. Type: Expression profiling by high throughput sequencing.
Nitazoxanide impairs mitophagy flux through ROS-mediated mitophagy initiation and lysosomal dysfunction in bladder cancer
GEO Series GSE171129. Homo sapiens. 2 samples. Type: Expression profiling by high throughput sequencing.
The MAPK14/MAPK7/BCL6B pathway creates a positive feedback loop to drive spermatogonial stem cell (SSC) self-renewal via ROS amplification.
GEO Series GSE118191. Mus musculus. 16 samples. Type: Expression profiling by high throughput sequencing.
NOX1 is essential for TNFα-induced intestinal epithelial ROS secretion and inhibits M cell differentiation [scRNA-seq]
GEO Series GSE202675. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing.
Targeting Mediator MED23 inhibits HCC development by inhibiting compensatory proliferation and promoting ROS-mediated cell death [RNA-Seq]
GEO Series GSE295431. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing.
Data from: Fe-S cluster biosynthesis controls uptake of aminoglycosides in a ROS-less death pathway
All bactericidal antibiotics were recently proposed to kill by inducing reactive oxygen species (ROS) production, causing destabilization of iron-sulfur (Fe-S) clusters and generating Fenton chemistry. We find that the ROS response is dispensable upon treatment with bactericidal antibiotics. Furthermore, we demonstrate that Fe-S clusters are required for killing only by aminoglycosides. In contrast to cells, using the major Fe-S cluster biosynthesis machinery, ISC, cells using the alternative machinery, SUF, cannot efficiently mature respiratory complexes I and II, resulting in impendence of the proton motive force (PMF), which is required for bactericidal aminoglycoside uptake. Similarly, during iron limitation, cells become intrinsically resistant to aminoglycosides by switching from ISC to SUF and down-regulating both respiratory complexes. We conclude that Fe-S proteins promote aminoglycoside killing by enabling their uptake.
ROS-Specific Huntingtin Interactions: Huntingtin pulldown of PARylated proteins
<p>Huntingtin co-immunoprecipitation of proteins modified by poly ADP ribose.</p>
ROS-Specific Huntingtin Interactions: Testing PAR binding of huntingtin purified with nickel or heparin
<p>Attempts to test PAR binding of huntingtin purified with nickel or heparin.</p>
Novel ROS-scavenging Nanoenzymes for the Treatment of Radiation Dermatitis in Patients With Head and Neck Cancer
ClinicalTrials.gov study NCT07064577. IPD Sharing: NO. Countries: 1. Publications: 0.
Study on the Mechanism of Zuoqing San Promoting Postoperative Wound Healing of Anal Fistula by Inhibiting ROS-dependent NETosis
ClinicalTrials.gov study NCT07128953. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Mediterranean Dietary Intervention on ROS Levels and TAC During Pregnancy
ClinicalTrials.gov study NCT07214402. IPD Sharing: NO. Countries: 1. Publications: 0.
Lorlatinib for Newly-Diagnosed High-Grade Glioma With ROS or ALK Fusion
ClinicalTrials.gov study NCT06333899. IPD Sharing: NO. Countries: 6. Publications: 0.
Impact of NOS, COX, and ROS Inhibition on Cerebral Blood Flow Regulation
ClinicalTrials.gov study NCT03066115. IPD Sharing: NO. Countries: 1. Publications: 0.
ROS-Scavenging Nanozyme Combined With Thermotherapy Alleviate Radiation Dermatitis in Patients With Head and Neck Cancer
ClinicalTrials.gov study NCT07086638. IPD Sharing: NO. Countries: 1. Publications: 0.
Role of ROS and cAMP-PKA Biomarkers in ADPKD
ClinicalTrials.gov study NCT07217158. IPD Sharing: NO. Countries: 1. Publications: 0.
Clinical Relevance of ROS (V-ros UR2 Sarcoma Virus Oncogene Homolog) Aberrations in Solid Tumours
ClinicalTrials.gov study NCT01596374. IPD Sharing: Not stated. Countries: 1. Publications: 0.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.