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365 results for “Urinary tract infections”
Controlling Antimicrobial Use Through Reducing Unnecessary Treatment of Catheter Associated Urinary Tract Infections
ClinicalTrials.gov study NCT02650518. IPD Sharing: Not stated. Countries: 1. Publications: 18.
Clinical Trial on the Preventive Effect of Intravaginal Prasterone on Recurrent Urinary Tract Infections in Postmenopausal Women
ClinicalTrials.gov study NCT03854396. IPD Sharing: YES. Countries: 1. Publications: 9.
Immediate vs. Conditional Use of Antibiotics in Uncomplicated Urinary Tract Infection (UTI) - ICUTI
ClinicalTrials.gov study NCT01488955. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Preference of Women With Recurrent Urinary Tract Infection for Vaginal Estradiol Tablet vs Cream
ClinicalTrials.gov study NCT05723601. IPD Sharing: NO. Countries: 1. Publications: 14.
Improving Antibiotic Prescribing for Urinary Tract Infections in Frail Elderly
ClinicalTrials.gov study NCT03970356. IPD Sharing: NO. Countries: 4. Publications: 3.
Vitamin C Effectiveness in Preventing Urinary Tract Infections After Gynecological Surgeries
ClinicalTrials.gov study NCT05913180. IPD Sharing: NO. Countries: 1. Publications: 7.
Dipsticks and Microscopy to Reduce Antibiotic Use in Women's Urinary Tract Infections: a Pilot Trial (MicUTI)
ClinicalTrials.gov study NCT05667207. IPD Sharing: NO. Countries: 1. Publications: 4.
Safety and Tolerability of Ertapenem Sodium in the Treatment of Complicated Urinary Tract Infections (0826-055)
ClinicalTrials.gov study NCT01014013. IPD Sharing: YES. Countries: 0. Publications: 1.
Prevention of Renal Failure in Children With Urinary Tract Infections
ClinicalTrials.gov study NCT00316043. IPD Sharing: Not stated. Countries: 1. Publications: 8.
Vaccine for Recurrent Urinary Tract Infections in Women
ClinicalTrials.gov study NCT00261248. IPD Sharing: Not stated. Countries: 1. Publications: 1.
'Improving Urinary Tract Infection Diagnosis in Older Patients: Validation of a Biomarker Panel (UTI-GOLD)'
ClinicalTrials.gov study NCT06610721. IPD Sharing: YES. Countries: 1. Publications: 1.
A Study of Plazomicin Compared With Meropenem for the Treatment of Complicated Urinary Tract Infection (cUTI) Including Acute Pyelonephritis (AP)
ClinicalTrials.gov study NCT02486627. IPD Sharing: Not stated. Countries: 0. Publications: 1.
A Study of Efficacy and Safety of Intravenous Cefiderocol (S-649266) Versus Imipenem/Cilastatin in Complicated Urinary Tract Infections
ClinicalTrials.gov study NCT02321800. IPD Sharing: Not stated. Countries: 0. Publications: 4.
Data from: Analytical performance, agreement and user-friendliness of six point of care testing urine analysers for urinary tract infection in general practice.
Objective: Various point-of-care testing (POCT) urine analysers are commercially available for routine urine analysis in general practice. The present study compares analytical performance, agreement and user-friendliness of six different POCT urine analysers for diagnosing urinary tract infection in general practice. Setting: All testing procedures were performed at a diagnostic centre for primary care in the Netherlands. Urine samples were collected at four general practices. Primary and secondary outcome measures: Analytical performance and agreement of the POCT analysers regarding nitrite, leucocytes and erythrocytes, with the laboratory reference standard, was the primary outcome measure, and analysed by calculating sensitivity, specificity, positive and negative predictive value, and Cohen's κ coefficient for agreement. Secondary outcome measures were the user-friendliness of the POCT analysers, in addition to other characteristics of the analysers. Results: The following six POCT analysers were evaluated: Uryxxon Relax (Macherey Nagel), Urisys 1100 (Roche), Clinitek Status (Siemens), Aution 11 (Menarini), Aution Micro (Menarini) and Urilyzer (Analyticon). Analytical performance was good for all analysers. Compared with laboratory reference standards, overall agreement was good, but differed per parameter and per analyser. Concerning the nitrite test, the most important test for clinical practice, all but one showed perfect agreement with the laboratory standard. For leucocytes and erythrocytes specificity was high, but sensitivity was considerably lower. Agreement for leucocytes varied between good to very good, and for the erythrocyte test between fair and good. First-time users indicated that the analysers were easy to use. They expected higher productivity and accuracy when using these analysers in daily practice. Conclusions: The overall performance and user-friendliness of all six commercially available POCT urine analysers was sufficient to justify routine use in suspected urinary tract infections in general practice.
raw data - Pharmacokinetic/ pharmacodynamic analysis based on the data from a randomized phase I study justifies the optimal dosing regimens of the 10:1 formulation of amoxicillin/clavulanic acid for treatment of respiratory and urinary tract infections
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Supplementary material 1 from: Sabdono A, Lestari ES, Sibero MT (2022) Biogeographic assessment of Gorgonian-associated bacteria with antipathogenic Urinary Tract Infections (UTIs) in Karimunjawa Marine National Park, Java Sea, Indonesia. Nature Conservation 49: 137-151. https://doi.org/10.3897/natureconservation.49.84825
Tables S1–S3
Data from: Portable bacteria-capturing chip for direct surface-enhanced Raman scattering identification of urinary tract infection pathogens
Acute urinary tract infections (UTIs) are one of the most common nosocomial bacterial infections, which affect almost 50% of the population at least once in their lifetime. UTIs may lead to lethal consequences if they are left undiagnosed and untreated properly. Early, rapid and accurate uropathogens detection methods play a pivotal role in clinical process. In this work, a portable bacteria-grasping surface-enhanced Raman scattering (SERS) chip for identification of three species of uropathogens (E. coli CFT 073, P. aeruginosa PAO1, and P. mirabilis PRM1) directly from culture matrix was reported. The chip was firstly modified with a positively-charged NH3+ group, which enable itself grasp the negatively-charged bacterial cells through the electrostatic adsorption principle. After the bacterial cells were captured by the chip, concentrated Ag nanoparticles (NPs) were used to obtain their Raman fingerprint spectra with recognizable characteristic peaks and good reproducibility. With the help of chemometric method such as discriminant analysis (DA), the SERS based chip allows a rapid, successful identification of three species of UTI bacteria with a minimal bacterial concentration (105 cells/mL) required for clinical diagnostics. In addition, this chip could spot the bacterial SERS fingerprints information directly from LB culture medium and artificial urine without sample pre-treatment. The portable bacteria-grasping SERS based chip provides a possibility for fast and easy detection of uropathogens, and viability of future development in healthcare applications.
A Study in Adolescent and Adult Female Participants to Evaluate Clinical Symptom Improvement and the Safety of Gepotidacin During Treatment of Uncomplicated Urinary Tract Infections (Acute Cystitis)
ClinicalTrials.gov study NCT06597344. IPD Sharing: YES. Countries: 1. Publications: 0.
A Study to Investigate the Efficacy and Safety With Gepotidacin in Japanese Female Participants With Uncomplicated Urinary Tract Infection (Acute Cystitis)
ClinicalTrials.gov study NCT05630833. IPD Sharing: YES. Countries: 1. Publications: 0.
Prevention of Catheter-Associated Urinary Tract Infection in Incontinence and Reconstructive Pelvic Surgery Patients
ClinicalTrials.gov study NCT01108757. IPD Sharing: Not stated. Countries: 1. Publications: 0.
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