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445
datasets available to search
ShareScore release 0.9.0
Dataset results
445 results for “diabetic retinopathy”
The Diabetic Retinopathy Screening, Prevention and Control Program
ClinicalTrials.gov study NCT04240652. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Biomarkers of Diabetic Retinopathy Progression
ClinicalTrials.gov study NCT01607190. IPD Sharing: Not stated. Countries: 2. Publications: 1.
Computer-based Screening for Diabetic Retinopathy
ClinicalTrials.gov study NCT01614327. IPD Sharing: Not stated. Countries: 1. Publications: 21.
Effectiveness of Multimodal Imaging for the Evaluation of Retinal Oedema And New vesseLs in Diabetic Retinopathy
ClinicalTrials.gov study NCT03490318. IPD Sharing: UNDECIDED. Countries: 1. Publications: 3.
Study on Precision Treatment of Diabetic Retinopathy Macular Edema Guided by Real-time OCT During Operation
ClinicalTrials.gov study NCT05138029. IPD Sharing: NO. Countries: 1. Publications: 0.
A Longitudinal Study of Choroidal Changes After Cataract Surgery in Eyes With Diabetic Retinopathy
ClinicalTrials.gov study NCT04499768. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Improve Timely Referral Flow and Compliance of Diabetic Retinopathy Patients
ClinicalTrials.gov study NCT04834648. IPD Sharing: NO. Countries: 1. Publications: 1.
Study of Effectiveness of Telemedicine in Identifying Diabetic Retinopathy Cases
ClinicalTrials.gov study NCT02085681. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Data from: Systematic review on barriers and enablers for access to diabetic retinopathy screening services in different income settings
Open the record for dataset details and reuse information.
Data from: Integration of genomics and transcriptomics predicts diabetic retinopathy susceptibility genes
<p class="Normal1">We determined differential gene expression in response to high glucose in lymphoblastoid cell lines derived from matched individuals with type 1 diabetes with and without retinopathy. Those genes exhibiting the largest difference in glucose response were assessed for association to diabetic retinopathy in a genome-wide association study meta-analysis. Expression Quantitative Trait Loci (eQTLs) of the glucose response genes were tested for association with diabetic retinopathy. We detected an enrichment of the eQTLs from the glucose response genes among small association p-values and identified <i>FLCN</i> as a susceptibility gene for diabetic retinopathy. Expression of <i>FLCN </i>in response to glucose was greater in individuals with diabetic retinopathy. Independent cohorts of individuals with diabetes revealed an association of <i>FLCN</i> eQTLs to diabetic retinopathy. Mendelian randomization confirmed a direct positive effect of increased <i>FLCN</i> expression on retinopathy. Integrating genetic association with gene expression implicated <i>FLCN </i>as a disease gene for diabetic retinopathy.</p>
Data from: Potential role of Cyr61 induced degeneration of human Müller cells in diabetic retinopathy
The degeneration of Müller cells has been recognized to involve in the pathogenesis of diabetic retinopathy. However, the mechanism is not yet clear. This study is to explore the potential role of Cyr61, a secreted signaling protein in extracellular matrix, in inducing human Müller cell degeneration in diabetic retinopathy (DR). Twenty patients with proliferative diabetic retinopathy (PDR) and twelve non-diabetic patients were recruited for this study. Vitreous fluid was collected during vitrectomy surgery for Cyr61 ELISA. Human Müller cell line MIO-M1 were cultured to be subconfluent, and then treated with glucose (0–20 mM) or Cyr61 (0–300 ng/ml). Cyr61 expression induced by increasing concentrations of glucose was evaluated by RT-qPCR and Western blot. Effects of Cyr61 on Müller cells viability, migration and apoptosis were observed by MTT assay, Transwell assay, and TUNEL assay. Vitreous Cyr61 levels were observed to be 8-fold higher in patients with PDR (3576.92±1574.58 pg/mL), compared with non-diabetic controls (436.14±130.69 pg/mL). Interestingly, the active PDR group was significantly higher than the quiescent PDR group (P<0.01). In retinal Müller cells culture, high glucose significantly and dose-dependently elevated Cyr61 expression at both mRNA and protein levels. Cyr61 at high concentrations dose-dependently inhibited the viability and migration of Müller cells. TUNEL assay further revealed that high concentration of Cyr61 significantly promoted the cell apoptosis. In conclusion, these findings demonstrated for the first time that the expression of Cyr61 was elevated by high glucose in Müller cells, and Cyr61 inhibited cell viability and migration while induced apoptosis, suggesting the potential role of Cyr61 in Müller cell degeneration. The elevated Cyr61 levels in vitreous fluid of PDR patients further support its role in diabetic retinopathy (DR).
Diabetic Retinopathy Patient Survey Data
<p>Patient survey data</p>
Diabetic Retinopathy Study (DRS)
ClinicalTrials.gov study NCT00000160. IPD Sharing: Not stated. Countries: 0. Publications: 12.
Performance Evaluation of Artificial Intelligence Assisted Diabetic Retinopathy Grading in the Leuven University Hospital: Can Technology Improve the Resident?
ClinicalTrials.gov study NCT05260281. IPD Sharing: NO. Countries: 0. Publications: 10.
Efficacy and Safety of AEYE-DS Software Device for Automated Detection of Diabetic Retinopathy From Digital Fundus Images
ClinicalTrials.gov study NCT04612868. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Conbercept Injection in Treatment of Severe Proliferative Diabetic Retinopathy
ClinicalTrials.gov study NCT02816710. IPD Sharing: NO. Countries: 1. Publications: 0.
A Study to Evaluate the Efficacy and Safety of Intravitreal KSI-301 in Non-proliferative Diabetic Retinopathy (NPDR)
ClinicalTrials.gov study NCT05066230. IPD Sharing: NO. Countries: 7. Publications: 0.
A Single-center, Retrospective Study to Evaluate the Clinical Performance of Artificial Intelligence Medical Assisted Diagnostic Software (VeriSee DR) for Screening of Diabetic Retinopathy in Patients
ClinicalTrials.gov study NCT04160988. IPD Sharing: Not stated. Countries: 1. Publications: 0.
A Study of Keluo Xin Capsule Compare to Placebo in Terms of Efficacy and Safety in Patients With Diabetic Retinopathy
ClinicalTrials.gov study NCT03258242. IPD Sharing: UNDECIDED. Countries: 0. Publications: 1.
Dyslipidemia and Diabetic Retinopathy
ClinicalTrials.gov study NCT03403283. IPD Sharing: Not stated. Countries: 1. Publications: 0.
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.