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159
datasets available to search
ShareScore release 0.9.0
Dataset results
159 results for “genetic heterogeneity”
Functional heterogeneity exceeds genetic heterogeneity in chronic myelomonocytic leukemia
GEO Series GSE114115. Homo sapiens. 10 samples. Type: Methylation profiling by high throughput sequencing.
A laboratory-based model ecosystem reveals genetic determinants of methanotroph phenotypic heterogeneity in a methane-oxygen counter gradient
GEO Series GSE243827. Methylomonas sp. LW13. 9 samples. Type: Expression profiling by high throughput sequencing.
Mouse models of genetically heterogeneous multiple myeloma reveal mechanisms of immune evasion that predict clinical immunotherapy responses
GEO Series GSE205447. Homo sapiens; Mus musculus. 133 samples. Type: Expression profiling by high throughput sequencing.
Cell-type and dynamic state govern genetic regulation of gene expression in heterogeneous differentiating cultures
GEO Series GSE266500. Homo sapiens. 102 samples. Type: Expression profiling by high throughput sequencing.
Controlling Genetic Heterogeneity in Gene-edited Hematopoietic Stem Cells by Single Cell Expansion
GEO Series GSE232527. Mus musculus. 9 samples. Type: Expression profiling by high throughput sequencing.
Data from: The genetics of phenotypic plasticity. XII. Temporal and spatial heterogeneity
In order to understand empirical patterns of phenotypic plasticity, we need to explore the complexities of environmental heterogeneity and how it interacts with cue reliability. I consider both temporal and spatial variation separately and in combination, the timing of temporal variation relative to development , the timing of movement relative to selection, and two different patterns of movement: stepping-stone and island. Among-generation temporal heterogeneity favors plasticity, while within-generation heterogeneity can result in cue unreliability. In general, spatial variation more strongly favors plasticity than temporal variation, and island migration more strongly favors plasticity than stepping-stone migration. Negative correlations among environments between the time of development and selection can result in seemingly maladaptive reaction norms. The effects of higher dispersal rates depends on the life history stage when dispersal occurs and the pattern of environmental heterogeneity. Thus, patterns of environmental heterogeneity can be complex and can interact in unforeseen ways to affect cue reliability. Proper interpretation of patterns of trait plasticity require consideration of the ecology and biology of the organism. More information on actual cue reliability and the ecological and developmental context of trait plasticity is needed.
Genetic Heterogeneity of Early-Onset Colorectal Cancer in Asian Populations: A Comprehensive Systematic Review
<p>Genetic Heterogeneity of Early-Onset Colorectal Cancer in Asian Populations: A Comprehensive Systematic Review</p>
Interest of High-throughput Sequencing of RNAs for the Diagnosis of Heterogeneous Genetic Diseases
ClinicalTrials.gov study NCT03971292. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
A Neurobiological Study on Heterogeneity of Schizophrenia: Genetic Variations and Neurobiological Differentiations
ClinicalTrials.gov study NCT01075373. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Single Cell triple omics sequencing reveals genetic and epigenetic heterogeneity in hepatocellular carcinoma
GEO Series GSE65364. Homo sapiens; Mus musculus. 95 samples. Type: Expression profiling by high throughput sequencing; Methylation profiling by high throughput sequencing.
Mapping genotype-expression associations in Heterogeneous Stock rat brains to advance behavioral genetics research [Orbitofrontal cortex]
GEO Series GSE173140. Rattus norvegicus. 88 samples. Type: Expression profiling by high throughput sequencing.
Mapping genotype-expression associations in Heterogeneous Stock rat brains to advance behavioral genetics research [Lateral habenula]
GEO Series GSE173138. Rattus norvegicus. 87 samples. Type: Expression profiling by high throughput sequencing.
Mapping genotype-expression associations in Heterogeneous Stock rat brains to advance behavioral genetics research [Prelimbic cortex]
GEO Series GSE173139. Rattus norvegicus. 86 samples. Type: Expression profiling by high throughput sequencing.
Data from: The genetics of phenotypic plasticity. XII. Temporal and spatial heterogeneity
Open the record for dataset details and reuse information.
Canagliflozin treatment prevents follicular exhaustion and attenuates hallmarks of ovarian aging in genetically heterogenous mice
GEO Series GSE283764. Mus musculus. 15 samples. Type: Expression profiling by high throughput sequencing.
Reduced genetic tumor heterogeneity after neoadjuvant chemotherapy is related to favorable outcome in patients with esophageal adenocarcinoma
GEO Series GSE56106. Homo sapiens. 75 samples. Type: Genome variation profiling by genome tiling array.
Multi-omics data and stochastic simulations support a cancer heterogeneity framework unifying genetic, epigenetic, and stochastic variabilities [scRNA-seq]
GEO Series GSE150083. Homo sapiens. 2 samples. Type: Expression profiling by high throughput sequencing.
Therapeutic targeting of Notch signaling and immune checkpoint blockade in a spontaneous, genetically-heterogeneous mouse model of T-cell acute lymphoblastic leukemia
GEO Series GSE137181. Mus musculus. 42 samples. Type: Expression profiling by high throughput sequencing; Genome variation profiling by high throughput sequencing.
Pre-clinical models for prediction of immunotherapy outcomes and immune evasion mechanisms in genetically heterogeneous multiple myeloma
GEO Series GSE220997. Mus musculus. 108 samples. Type: Expression profiling by high throughput sequencing; Other; Genome variation profiling by high throughput sequencing.
Genetic heterogeneity versus molecular analysis of prion susceptibility in neuroblasma N2a sublines
GEO Series GSE5374. Mus musculus. 9 samples. Type: Genome variation profiling by genome tiling array.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.