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150
datasets available to search
ShareScore release 0.9.0
Dataset results
150 results for “host microbiome”
Multi-omics analysis revealing the interplay between gut microbiome and the host following opioid use
GEO Series GSE230096. Mus musculus. 22 samples. Type: Expression profiling by high throughput sequencing.
Microbiome remodeling through bacterial competition and host behavior enables rapid adaptation to environmental toxins
GEO Series GSE246966. Caenorhabditis elegans. 12 samples. Type: Expression profiling by high throughput sequencing.
Associations between host gene expression, the mucosal microbiome, and clinical outcome in the pelvic pouch of patients with inflammatory bowel disease.
GEO Series GSE65270. Homo sapiens. 273 samples. Type: Expression profiling by array.
Novel Interactions between Gut Microbiome and Host Drug-processing Genes Modify the Hepatic Metabolism of the Environmental Chemicals PBDEs
GEO Series GSE101650. Mus musculus. 18 samples. Type: Expression profiling by high throughput sequencing.
Metabolic products of an obesity-associated microbiome impact host metabolism and disease risk by altering the epigenome
GEO Series GSE99327. Mus musculus. 12 samples. Type: Expression profiling by array.
Differences in the microbiome of the small intestine of Leghorn lines divergently selected for antibody titer to sheep erythrocytes suggest roles for commensals in host humoral response
GEO Series GSE240908. Gallus gallus. 36 samples. Type: Other.
Vaginal Microbiome-host Interaction in Mesh Exposure After TVM Surgery
ClinicalTrials.gov study NCT05000112. IPD Sharing: Not stated. Countries: 0. Publications: 0.
Characterization of antibiotic resistance and host-microbiome interactions in the human upper respiratory tract during influenza infection
GEO Series GSE126902. human metagenome. 69 samples. Type: Expression profiling by high throughput sequencing; Other.
A small intestinal bile acid modulates the gut microbiome to improve host metabolic phenotypes following bariatric surgery
GEO Series GSE262065. Mus musculus. 10 samples. Type: Expression profiling by high throughput sequencing.
Specific Host Metabolite and Gut Microbiome Alterations Are Associated with Bone-loss During Spaceflight
Understanding the axis of the human microbiome and physiological homeostasis is an essential task in managing deep-space travel associated health risks. The NASA led Rodent Research 5 mission enabled an ancillary investigation of the gut microbiome varying exposure to microgravity (flight) relative to ground controls in the context of previously shown bone mineral density (BMD) loss that was observed in these flight groups. We demonstrate elevated abundance of Lactobacillus murinus and Dorea sp. during microgravity exposure relative to ground control through whole genome sequencing and 16S rRNA analyses. Specific functionally assigned gene clusters of Lactobacillus murinus and Dorea sp. capable of producing metabolites, lactic acid, leucine/isoleucine, and glutathione are enriched. These metabolites are elevated in the microgravity-exposed host serum through LC-MS/MS metabolomic analysis. Along with BMD loss, ELISA analysis reveals increases of osteocalcin and reductions in tartrate-resistant acid phosphatase 5b signifying additional loss of bone homeostasis in flight.
Reproducible changes in gut microbiome reveal a shift in microbial and host metabolism during spaceflight
Data were generated as part of a NASA-funded study (Turek F (PI) et al. Effects of Spaceflight on Gastrointestinal Microbiota in Mice: Mechanisms and Impact on Multi-System. NASA NRA: NRA NNH14ZTT002N). As part of the study, we requested and received samples from RR1. We generated 16S rRNA gene amplicon sequence data from DNA extracted from fecal samples, and compared these data to similar data generated on shuttle mission STS-135 and from ground-based studies of radiation. We assessed effect of flight conditions and radiation.
High Resolution Spatial Mapping of Microbiome-Host Interactions via in situ Polyadenylation and Spatial RNA Sequencing [bulk RNA-Seq]
GEO Series GSE316869. mouse gut metagenome. 4 samples. Type: Expression profiling by high throughput sequencing.
Dual-transcriptomic analysis of human nasal transcriptome and microbiome reveals host-bacteria interactions associated with symptomatic respiratory infection [RNA-Seq]
GEO Series GSE309130. Homo sapiens. 149 samples. Type: Expression profiling by high throughput sequencing.
C. difficile-associated antibiotics prime the host for infection by a microbiome-independent mechanism
GEO Series GSE135383. Homo sapiens. 27 samples. Type: Expression profiling by high throughput sequencing.
Dual-transcriptomic analysis of human nasal transcriptome and microbiome reveals host-bacteria interactions associated with symptomatic respiratory infection (16S validation)
GEO Series GSE309134. Homo sapiens. 53 samples. Type: Other.
The intestinal clock controls host’s metabolic response to diet by driving intestinal metabolic functions and the fiber-dependent microbiome
GEO Series GSE229963. Mus musculus. 48 samples. Type: Expression profiling by high throughput sequencing.
ChemProp2 Dataset: Investigating potential biotransformations with a panel of 45 Drugs on Synthetic Community (Com20) to elucidate Drug-Microbiome-Host Dynamics
<p>This dataset contains the examination of each of the 45 drugs on the synthetic community Com20, conducted at two distinct timepoints: initially (time 0) and after a 2-hour interval.<br>List of drugs: Ethopropazine, Methotrexate, Felodipine, Miconazole, Floxuridine, Nalidixic acid, Fluconazole, Niclosamide, Ketoconazole, Omeprazole, Lacidipine, Pentamidine isothionate, DMSO, Promethazine, Lansoprazole, Protriptyline, Loratadine, Sertindole, Loxapine, Simvastatin, L-Thyroxine, Streptozotocin, Metformin, Tamoxifen, Tazobactam, Doxorubicin, Telmisartan, Ofloxacin, Terfenadine, Oxolinic acid, Thioguanosine, Tobramycin, Tiratricol, Vancomycin, Water, Rivaroxoban, Metronidazole, Tolfenamic acid, Clarithromycin, Tribenoside, Norfloxacin, Zafirlukast, Montelukast, Sertraline, Fluoxetine, Clomipramin, Novobiocin</p>
ChemProp2 Dataset: Investigating potential biotransformations with a panel of 23 Drugs on Synthetic Community (Com20) to elucidate Drug-Microbiome-Host Dynamics
<p>Tested 23 drugs against Synthetic community (Com20) at two different timepoints (t=0, t= 2 hrs) to look for potential biotransformations<br><br>List of drugs tested:<br>Acarbose, Clemizole, Amlodipine, Clindamycin, Amoxicillin, Clomifen, Aprepitant, Clotrimazole, Avermectin B1, Diacerein, Azithromycin, Dicumarol, Control, Dienestrol, Benzbromarone, Dienogest, Ceterizin, Doxycycline hyclate, Chlorpromazine, Duloxetin, Chlorprothixene, Erythromycin, Cilnidipine, Ethinylestradiol<br><br>Samples were measured (in March 18/19, 2023) using an UHPLC-Q Exactive HF Orbitrap mass spectrometer, equipped with a C18 column, following the LC-MS/MS method.</p>
Distinct actions of the cold water on host metabolism, gut barrier and microbiome-metabolites gut-brain modules in mice
GEO Series GSE178571. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Comprehensive multi-omics analysis of microbiome, metabolome, and host genome in right- and left-sided colon cancer
GEO Series GSE216022. Homo sapiens. 59 samples. Type: Expression profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.