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303 results for “individual difference”
Data and code archive for 'Time perception and patience: Individual differences in interval timing precision predict choice impulsivity in European starlings, Sturnus vulgaris'
<p>Data and code for Andrews et al. '<strong>Time perception and patience: Individual differences in interval timing precision predict choice impulsivity in European starlings, <em>Sturnus vulgaris'</em></strong></p> <p>Version of November 02 2020</p> <p>The data are presented here with different degrees of processing (i.e. from every trial on every day by every bird separately in 'timing data.Rdata', to one summary row per bird in 'timing data by bird.csv'). Separate scripts do the processing, fit polynomials, reproduce the by-bird analyses in the paper, and run the numerical model. Please see the document 'Description of R scripts and files' for details of the different versions of the data and what each script does.</p> <p> </p>
Data from: Individual differences in torpor expression in adult mice are related to relative birth weight
Daily torpor is a physiological adaptation in small mammals and birds, characterised by drastic reductions in metabolism and body temperature. Energy-constraining conditions, such as cold and starvation, are known to cause the expression of daily torpor. However, the reason for high degrees of inter- and intra- individual variation in torpor expression (TE) in similar situations is not clear. As littermates of altricial animals are exposed to an uneven allocation of maternal resources from conception to weaning, we tested whether early nutritional experiences have long-term effects on TE in adults. We used full-sibling littermates of laboratory mice that as adults were starved overnight to induce torpor. We measured body weight from birth until adulthood as an indicator of nutritional status, and calculated the relative body weight (RBW) as an indicator of the difference in nutritional status within a litter. After maturation, we subjected mice to five repeated torpor induction trials involving 24 hours of fasting and 5 days of recovery. Half of the female mice displayed great individual variation in TE, whereas male mice rarely exhibited daily torpor. In females, RBW at birth influenced TE, irrespective of body weight in adulthood; thus, female mice born with low RBWs displayed high TE in adulthood. In conclusion, we provide evidence that TE in mice differs among littermates, and that this variation is linked closely to heterogeneous nutritional experiences during the foetal period.
Data from: Combining animal personalities with transcriptomics resolves individual variation within a wild-type zebrafish population and identifies underpinning molecular differences in brain function
Resolving phenotype variation within a population in response to environmental perturbation is central to understanding biological adaptation. Relating meaningful adaptive changes at the level of the transcriptome requires the identification of processes that have a functional significance for the individual. This remains a major objective towards understanding the complex interactions between environmental demand and an individual's capacity to respond to such demands. The interpretation of such interactions and the significance of biological variation between individuals from the same or different populations remain a difficult and under-addressed question. Here, we provide evidence that variation in gene expression between individuals in a zebrafish population can be partially resolved by a priori screening for animal personality and accounts for >9% of observed variation in the brain transcriptome. Proactive and reactive individuals within a wild-type population exhibit consistent behavioural responses over time and context that relates to underlying differences in regulated gene networks and predicted protein–protein interactions. These differences can be mapped to distinct regions of the brain and provide a foundation towards understanding the coordination of underpinning adaptive molecular events within populations.
Data from: Orientation-invariance of individual differences in three face processing tasks
Numerous studies have reported impairments in perception and recognition, and, particularly, in part-integration of faces following picture-plane inversion. Whether these findings support the notion that inversion changes face processing qualitatively remains a topic of debate. To examine whether associations and dissociations of the human face processing ability depend on stimulus orientation, we measured face recognition with the Cambridge Face Memory Test (CFMT), along with experimental tests of face perception and selective attention to faces and non-face objects in a sample of 314 participants. Results showed strong inversion effects for all face-related tasks, and modest ones for non-face objects. Individual differences analysis revealed that the CFMT shared common variance with face perception and face-selective attention, however, independent of orientation. Regardless of whether predictor and criterion had same or different orientation, face recognition was best predicted by the same test battery. Principal component decomposition revealed a common factor for face recognition and face perception, a second common factor for face recognition and face-selective attention, and two unique factors. The patterns of factor loadings were nearly identical for upright and inverted presentation. These results indicate orientation-invariance of common variance in three domains of face processing. Since inversion impaired performance, but did not affect domain-related associations and dissociations, the findings suggest process-specific but orientationgeneral mechanisms. Specific limitations by constraints of individual differences analysis and test selection are discussed.
Data from: Individual differences in selective attention predict speech identification at a cocktail party
Listeners with normal hearing show considerable individual differences in speech understanding when competing speakers are present, as in a crowded restaurant. Here, we show that one source of this variance are individual differences in the ability to focus selective attention on a target stimulus in the presence of distractors. In 50 young normal-hearing listeners, the performance in tasks measuring auditory and visual selective attention was associated with sentence identification in the presence of spatially separated competing speakers. Together, the measures of selective attention explained a similar proportion of variance as the binaural sensitivity for the acoustic temporal fine structure. Working memory span, age, and audiometric thresholds showed no significant association with speech understanding. These results suggest that a reduced ability to focus attention on a target is one reason why some listeners with normal hearing sensitivity have difficulty communicating in situations with background noise.
Data from: Conformity in the collective: differences in hunger affect individual and group behaviour in fish
Animal groups are often composed of individuals that vary according to behavioural, morphological and internal state parameters. Understanding the importance of such individual-level heterogeneity to the establishment and maintenance of coherent group responses is of fundamental interest in collective behaviour. We examined the influence of hunger on the individual and collective behaviour of groups of shoaling fish, x-ray tetras (Pristella maxillaris). Fish were assigned to one of two nutritional states, satiated or hungry, and then allocated to 5 treatments that represented different ratios of satiated to hungry individuals (8 hungry, 8 satiated, 4:4 hungry: satiated, 2:6 hungry: satiated, 6:2 hungry: satiated). Our data show that groups with a greater proportion of hungry fish swam faster and exhibited greater nearest-neighbour distances. Within groups, however, there was no difference in the swimming speeds of hungry versus well-fed fish, suggesting that group members conform and adapt their swimming speed according to the overall composition of the group. We also found significant differences in mean group transfer entropy, suggesting stronger patterns of information flow in groups comprising all, or a majority of, hungry individuals. In contrast, we did not observe differences in polarization, a measure of group coherence, within groups across treatments. Taken together these results demonstrate that the nutritional state of animals within social groups impacts both individual and group behaviour, and that members of heterogenous groups can adapt their behaviour to facilitate coherent collective motion.
Data from: Quantifying individual heterogeneity and its influence on life-history trajectories: different methods for different questions and contexts
Heterogeneity among individuals influences the life-history trajectories we observe at the population level because viability selection, selective immigration and emigration processes, and ontogeny change the proportion of individuals with specific trait values with increasing age. Here, we review the two main approaches that have been proposed to account for these processes in life-history trajectories, contrasting how they quantify ontogeny and selection, and proposing ways to overcome some of their limitations. Nearly all existing approaches to model individual heterogeneity assume either a single normal distribution or a priori known groups of individuals. Ontogenetic processes, however, can vary across individuals through variation in life-history tactics. We show the usefulness of describing ontogenetic processes by modelling trajectories with a mixture model that focuses on heterogeneity in life-history tactics. Additionally, most methods examine individual heterogeneity in a single trait, ignoring potential correlations among multiple traits caused by latent common sources of individual heterogeneity. We illustrate the value of using a joint modelling approach to assess the presence of a shared latent correlation and its influence on life-history trajectories. We contrast the strengths and limitations of different methods for different research questions, and we exemplify the differences among methods using empirical data from long-term studies of ungulates.
Data from: Using a robotic fish to investigate individual differences in social responsiveness in the guppy
Responding towards the actions of others is one of the most important behavioral traits whenever animals of the same species interact. Mutual influences among interacting individuals may modulate the social responsiveness seen and thus makes it often difficult to study the level and individual variation in responsiveness. Here, open-loop biomimetic robots that provide standardized, non-interactive social cues can be a useful tool. These robots are not affected by the live animal's actions but are assumed to still represent valuable and biologically relevant social cues. As this assumption is crucial for the use of biomimetic robots in behavioral studies, we hypothesized (a) that meaningful social interactions can be assumed if live animals maintain individual differences in responsiveness both when interacting with a biomimetic robot and a live partner. Furthermore, to study the level of individual variation in social responsiveness, we hypothesized (b) that individual differences should be maintained over the course of multiple tests with the robot. We investigated the response of live guppies (Poecilia reticulata) when allowed to interact either with a biomimetic open-loop controlled fish robot – 'Robofish' – or a live companion. Furthermore we investigated the responses of live guppies when tested three times with Robofish. We found that live guppies' responses towards Robofish were weaker compared to a live companion, most likely as a result of the non-interactive open-loop behavior of Robofish. Guppies, however, were consistent in their individual responses between a live companion and Robofish and similar individual differences in response towards Robofish were maintained over repeated testing even though habituation to the test environment was detectable. Biomimetic robots like Robofish are therefore a useful tool for the study of social responsiveness in guppies and possibly other small fish species.
LENGTH DIFFERENCES OF INDIVIDUAL YARN AND SINGLE YARN ELONGATION DEFORMATIONS IN COOKED YARN COMPOSITION.
Open the record for dataset details and reuse information.
Difference in rupture risk between familial and sporadic intracranial aneurysms: an individual patient data meta-analysis
<p><b>Objective:</b> We combined <span>individual patient data (IPD) from prospective cohorts of patients with </span>unruptured intracranial aneurysms (UIA) to assess to what extent patients with familial UIA have a higher rupture risk than those with sporadic UIA.<b> </b></p> <p><b>Methods:</b> For this IPD meta-analysis we performed an Embase and Pubmed search for studies published up to December 1, 2020. We included studies that 1) had a prospective study design; 2) included 50 or more patients with UIA; 3) studied the natural course of UIA and risk factors for aneurysm rupture including family history for aneurysmal subarachnoid haemorrhage and UIA; and 4) had aneurysm rupture as an outcome. Cohorts with available IPD were included. All studies included patients with newly diagnosed UIA visiting one of the study centers. The primary outcome was aneurysmal rupture. Patients with polycystic kidney disease and moyamoya disease were excluded. We compared rupture rates of familial versus sporadic UIA using a Cox proportional hazard regression model adjusted for the PHASES score and smoking. We performed two analyses: 1. only studies defining first-degree relatives as parents, children, and siblings and 2. all studies, thus both including and excluding siblings as first-degree relatives.</p> <p><b>Results:</b> We pooled IPD from eight cohorts with a low and moderate risk of bias. First-degree relatives were defined as parents, siblings and children in six cohorts (29% Dutch, 55% Finnish, 15% Japanese), totalling 2,297 patients (17% familial, 399 patients) with 3,089 UIA and 7,301 person-years follow-up. Rupture occurred in 10 familial patients (rupture rate: 0·89%/person-year; 95% CI:0·45-1·59) and 41 sporadic patients (0·66%/person-year; 95% CI:0·48-0·89); adjusted HR for familial patients 2·56 (95% CI: 1·18–5·56). After adding also the two cohorts excluding siblings as first-degree relatives resulting in 9,511 patients the adjusted HR was 1·44 (95% CI: 0·86–2·40).</p> <p><b>Conclusion:</b> The risk of rupture of UIA is two and a half times higher, with a range from a 1.2 to 5 times higher risk, in familial than in sporadic UIA. When assessing the risk of rupture in UIA, family history should be taken into account.</p>
Data from: Neural correlates of individual differences in circadian behavior
Daily rhythms in mammals are controlled by the circadian system, which is a collection of biological clocks regulated by a central pacemaker within the suprachiasmatic nucleus (SCN) of the anterior hypothalamus. Changes in SCN function have pronounced consequences for behaviour and physiology; however, few studies have examined whether individual differences in circadian behaviour reflect changes in SCN function. Here, PERIOD2::LUCIFERASE mice were exposed to a behavioural assay to characterize individual differences in baseline entrainment, rate of re-entrainment and free-running rhythms. SCN slices were then collected for ex vivo bioluminescence imaging to gain insight into how the properties of the SCN clock influence individual differences in behavioural rhythms. First, individual differences in the timing of locomotor activity rhythms were positively correlated with the timing of SCN rhythms. Second, slower adjustment during simulated jetlag was associated with a larger degree of phase heterogeneity among SCN neurons. Collectively, these findings highlight the role of the SCN network in determining individual differences in circadian behaviour. Furthermore, these results reveal novel ways that the network organization of the SCN influences plasticity at the behavioural level, and lend insight into potential interventions designed to modulate the rate of resynchronization during transmeridian travel and shift work..
Code and data for "Personality matters – The interplay between consistent individual differences and mouse welfare in female C57BL6/J mice"
<p>R code and data used for the manuscript "Personality matters – The interplay between consistent individual differences and mouse welfare in female C57BL6/J mice"</p>
Data from: Individual diet differences in a molluscivore shorebird are associated with the size of body instruments for internal processing rather than for feeding
Especially in birds, it is widely found that the size of individual prey items follows the size of the instruments of prey capture, handling and processing, i.e. bill size. In fact, this is the natural history basis of major discoveries on adaptative evolution in the face of changing food resources. In some birds, e.g. the molluscivore shorebirds ingesting hard-shelled prey, most of the prey processing process takes place within the digestive tract. This study of a salvaged sample of actively feeding great knots Calidris tenuirostris accidentally drowned in fishing nets in northern China, is the first documentation of diet selection at the level of the individual in previously well-studied molluscivore shorebirds. Diet composition was not associated with the length of the bill, but with the mass of the muscular gizzard. Gizzard mass, which unlike bill length is a phenotypically flexible trait, enables great knots to adjust to changing food resources as an individual, i.e. instantly responding to the food on offer. For migratory species like great knots which rely on seasonal sequences of inter distant feeding areas offering prey with a variety of characteristics, the capacity to individually adjust appears a key adaptation.
Endotoxin-induced Inflammatory and Behavioral Responses and Predictors of Individual Differences
ClinicalTrials.gov study NCT02529592. IPD Sharing: Not stated. Countries: 0. Publications: 2.
The Effect of Different Attention-Focused Training on Physical Performance and Cognitive Function in Geriatric Individuals
ClinicalTrials.gov study NCT06700928. IPD Sharing: NO. Countries: 0. Publications: 0.
Effectiveness of Varenicline: Testing Individual Differences
ClinicalTrials.gov study NCT01228175. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
Examining the Effects of Different Resistive Exercise Programs in Individuals with Compensated Liver Cirrhosis
ClinicalTrials.gov study NCT06749340. IPD Sharing: NO. Countries: 1. Publications: 0.
A Study of the Effectiveness of Different Anti-HIV Treatments in HIV-Positive Individuals Who Have Been on a Protease Inhibitor-Containing Drug Regimen for at Least 16 Weeks
ClinicalTrials.gov study NCT00000914. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Brain and Genetic Predictors of Individual Differences in Pain and Analgesia
ClinicalTrials.gov study NCT03781570. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Individual Differences in Drug Response
ClinicalTrials.gov study NCT03809546. IPD Sharing: NO. Countries: 1. Publications: 0.
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.