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136
datasets available to search
ShareScore release 0.9.0
Dataset results
136 results for “tissue targeting”
Identification of novel human Wnt target genes using adult endodermal tissue-derived organoids
GEO Series GSE167115. Homo sapiens. 45 samples. Type: Expression profiling by high throughput sequencing.
Ewing's sarcoma: an analysis of miRNA expression profiles and target genes in paraffin-embedded primary tumor tissue
GEO Series GSE80201. Mus musculus; Rattus norvegicus; synthetic construct; Homo sapiens. 24 samples. Type: Non-coding RNA profiling by array.
Targeting eIF4A-dependent translation in soft tissue sarcoma
GEO Series GSE227676. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing; Other.
Comprehensive characterisation of HNF4A and HNF1A genomic targets in pancreatic beta cells and hepatic cells reveals common and tissue-specific pathways and genes
GEO Series GSE206240. Homo sapiens. 42 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Identification of target genes in human lung tissue of COPD patients
GEO Series GSE106986. Homo sapiens. 19 samples. Type: Expression profiling by array.
Identification of Myc target genes in xenograft tissue derived from human lung cancers
GEO Series GSE15002. Homo sapiens. 24 samples. Type: Genome binding/occupancy profiling by array.
Integrating pharmacokinetics, tissue distribution, RNA sequencing, and network pharmacology identifies STAT1 and SERPINE1 as potential targets of moscatilin in treating liver diseases
GEO Series GSE312822. Mus musculus. 10 samples. Type: Expression profiling by high throughput sequencing.
Targeted transcriptome profiling of fresh paired normal and tumor tissue samples in glioblastoma patients
GEO Series GSE151352. Homo sapiens. 24 samples. Type: Expression profiling by high throughput sequencing.
Dataset related to article "Evaluation of target dose inhomogeneity in breast cancer treatment due to tissue elemental differences"
<p>This record contains raw data related to article "Evaluation of target dose inhomogeneity in breast cancer treatment due to tissue elemental differences"</p> <p>BACKGROUND:</p> <p>Monte Carlo simulations were run to estimate the dose variations generated by thedifference arising from the chemical composition of the tissues.</p> <p>METHODS:</p> <p>CT datasets of five breast cancer patients were selected. Mammary gland was delineated as clinical target volume CTV, as well as CTV_lob and CTV_fat, being the lobular and fat fractions of the entire mammary gland. Patients were planned for volumetric modulated arc therapy technique, optimized in the Varian Eclipse treatment planning system. CT, structures and plans were imported in PRIMO, based on Monte Carlo code Penelope, to run three simulations: AdiMus, where the adipose and muscle tissues were automatically assigned to fat and lobular fractions of the breast; Adi and Mus, where adipose and muscle, respectively were assigned to the whole mammary gland. The specific tissue density was kept identical from the CT dataset. Differences in mean doses in the CTV_lob and CTV_fat structures were evaluated for the different tissue assignments. Differences generated by the tissue composition and estimated by Acuros dose calculations in Eclipse were also analysed.</p> <p>RESULTS:</p> <p>From Monte Carlo simulations, the dose in the lobular fraction of the breast, when adipose tissue is assigned in place of muscle, is overestimated by 1.25 ± 0.45%; the dose in the fat fraction of the breast with muscle tissue assignment is underestimated by 1.14 ± 0.51%. Acuros showed an overestimation of 0.98 ± 0.06% and an underestimation of 0.21 ± 0.14% in the lobular and fat portions, respectively. Reason of this dissimilarity resides in the fact that the two calculations, Monte Carlo and Acuros, differently manage the range of CT numbers and the material assignments, having Acuros an overlapping range, where two tissues are both present in defined proportions.</p> <p>CONCLUSION:</p> <p>Although not clinically significant, the dose deposition difference in the lobular and connective fat fraction of the breast tissue lead to an improved knowledge of the possible dose distribution and homogeneity in the breast radiation treatment</p>
Targeting class A GPCRs for hard tissue regeneration [ATAC-seq]
GEO Series GSE217264. Homo sapiens. 2 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Targeting class A GPCRs for hard tissue regeneration
GEO Series GSE217437. Homo sapiens. 10 samples. Type: Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing; Expression profiling by array.
Gene expression in retinal tissue and off-target tissue derived from human iPSCs
GEO Series GSE197446. Homo sapiens. 5 samples. Type: Expression profiling by array.
RNA-sequencing analysis of aneurysmal tissues with or without treatment of targeted nanotherapy.
GEO Series GSE208025. Rattus norvegicus. 6 samples. Type: Expression profiling by high throughput sequencing.
Targeted DamID Detects Cell Type Specific Histone Modifications in intact tissues or organisms
GEO Series GSE278272. Drosophila melanogaster; Xenopus laevis; Mus musculus. 47 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Targeting class A GPCRs for hard tissue regeneration [microarray]
GEO Series GSE217436. Homo sapiens. 1 samples. Type: Expression profiling by array.
Expression of putative targets of immunotherapy in acute myeloid leukemia and healthy tissues
GEO Series GSE54781. Homo sapiens. 41 samples. Type: Expression profiling by RT-PCR.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.