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228 results for “uniformity”
Field Efficacy Of Insecticide Treated Uniforms And Skin Repellents for Malaria Prevention
ClinicalTrials.gov study NCT02938975. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Pure Florid and Pleomorphic Lobular Carcinoma in Situ of the Breast: Towards an Increasingly Uniform Management
ClinicalTrials.gov study NCT06133465. IPD Sharing: Not stated. Countries: 1. Publications: 14.
Study of Ocean Rowing Muscle Metabolism. 1. What Effect Does Rowing 3000 Miles Across Atlantic Ocean Have on Calf Muscle Size? 2. In the Catabolic State of Extreme Endurance, is Muscle Loss Uniform or
ClinicalTrials.gov study NCT05729841. IPD Sharing: NO. Countries: 1. Publications: 0.
Uniform FDG-PET Guided Gradient Dose Prescription to Reduce Late Radiation Toxicity
ClinicalTrials.gov study NCT02442375. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Data from: Spatial variability in a plant-pollinator community across a continuous habitat: high heterogeneity in the face of apparent uniformity
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Data from: Genetic uniformity characterizes the invasive spread of water hyacinth (Eichhornia crassipes), a clonal aquatic plant
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Distribution patterns of fungal taxa and inferred functional traits reflect the non-uniform vertical stratification of soil microhabitats in a coastal pine forest
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Data from: Non-uniform evolutionary response of gecko eye size to changes in diel activity patterns
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Data from: Phenotype uniformity in combined-stress environments has a different genetic architecture than in single-stress treatments
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Data from: Predicted effects of climate factors on mountain species are not uniform over different spatial scales
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Green spectrofluorimetric assay of dantrolene sodium via reduction method: application to content uniformity testing
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Globularia bisnagarica L. (Plantaginaceae) shows genetic uniformity throughout its disjunctive range
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Sarcomere length non-uniformities dictate force production along the descending limb of the force-length relation
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Figure 2 from: Koleva K, Todorova L, Marchev S, Vlaskovska M, Nikolov R (2020) Pharmacovigilance: procedures for uniform assessment of periodic safety update reports and their implementation in national settings. Focus on analgesics. Pharmacia 67(4): 283-288. https://doi.org/10.3897/pharmacia.67.e57134
Figure 2 A percentage of all active substances/products affected by the PSUR evaluation procedures. Legend: 1: The change is not implemented; 2: The change is implemented with an appropriate procedure; 3: The change is implemented outside the specified deadlines.
Figure 1 from: Koleva K, Todorova L, Marchev S, Vlaskovska M, Nikolov R (2020) Pharmacovigilance: procedures for uniform assessment of periodic safety update reports and their implementation in national settings. Focus on analgesics. Pharmacia 67(4): 283-288. https://doi.org/10.3897/pharmacia.67.e57134
Figure 1 Distribution of discrepancies by type of active substance for all active substances/products affected by the PSUR evaluation procedures. Legend: I: Total number of products by active substances; II: The change has not been implemented; III: The change is implemented by an appropriate procedure; IV: The change is implemented outside the specified deadlines.
Data from: The incidental response to uniform natural selection
When populations are exposed to novel conditions of growth they often become adapted to a similar extent, and at the same time evolve some degree of impairment in their original environment. They may also come to vary widely with respect to characters which are uncorrelated with fitness, as the result of chance genetic associations among the founders, when these are a small sample from a large and variable ancestral population. I report an experiment in which 240 replicate lines of the unicellular chlorophyte Chlamydomonas were derived from primarily photoautotrophic ancestors and cultured as heterotrophs in the dark. All adapted to the dark and were impaired in the light after several hundred generations of culture. They also displayed a wide range of colony morphologies that were uncorrelated with fitness. This incidental response to selection probably arose through random variation in the initial composition of the lines. The differences between closely related species or varieties may likewise arise, in similar circumstances, by sampling error rather than natural selection.
Data from: Isospectrals of non-uniform Rayleigh beams with respect to their uniform counterparts
In this paper, we look for non-uniform Rayleigh beams isospectral to a given uniform Rayleigh beam. Isospectral systems are those that have the same spectral properties, i.e. the same free vibration natural frequencies for a given boundary condition. A transformation is proposed that converts the fourth-order governing differential equation of non-uniform Rayleigh beam into a uniform Rayleigh beam. If the coefficients of the transformed equation match with those of the uniform beam equation, then the non-uniform beam is isospectral to the given uniform beam. The boundary-condition configuration should be preserved under this transformation. We present the constraints under which the boundary configurations will remain unchanged. Frequency equivalence of the non-uniform beams and the uniform beam is confirmed by the finite-element method. For the considered cases, examples of beams having a rectangular cross section are presented to show the application of our analysis.
Data from: Heterochrony in the evolution of Trinidadian guppy offspring size: maturation along a uniform ontogenetic trajectory
The size and maturity of Trinidadian guppy (Poecilia reticulata) offspring vary among populations adapted to environments of differential predation. Guppy offspring born to low-predation, high-competition environments are larger and more mature than their high-predation ancestors. Here we ask: what specific changes in developmental or birth timing occur to produce the larger, more mature neonates? We collected specimens across the perinatal window of development from five populations and quantified musculoskeletal maturation. We found that all populations undergo similar ontogenetic trajectories in skeletal and muscle acquisition; the only difference among populations is when neonates emerge along the trajectory. The smallest neonates are born with 20% of their skeleton ossified, whereas the largest neonates are born with over 70% of their skeleton ossified. The area of the major jaw-closing muscle is relatively larger in larger offspring, scaling with length as L2.5. The size range over which offspring are birthed among populations sits along the steepest part of the size–maturity relationship, which provides a large marginal increase in fitness for the high-competition female. Because of the functional effects of producing more mature offspring at birth, offspring size may be the first and most critical life-history trait selected upon in highly competitive environments.
Data from: Drosophila embryogenesis scales uniformly across temperature in developmentally diverse species
Temperature affects both the timing and outcome of animal development, but the detailed effects of temperature on the progress of early development have been poorly characterized. To determine the impact of temperature on the order and timing of events during Drosophila melanogaster embryogenesis, we used time-lapse imaging to track the progress of embryos from shortly after egg laying through hatching at seven precisely maintained temperatures between 17.5°C and 32.5°C. We employed a combination of automated and manual annotation to determine when 36 milestones occurred in each embryo. D. melanogaster embryogenesis takes 33 hours at 17.5°C, and accelerates with increasing temperature to a low of 16 hours at 27.5°C, above which embryogenesis slows slightly. Remarkably, while the total time of embryogenesis varies over two fold, the relative timing of events from cellularization through hatching is constant across temperatures. To further explore the relationship between temperature and embryogenesis, we expanded our analysis to cover ten additional Drosophila species of varying climatic origins. Six of these species, like D. melanogaster, are of tropical origin, and embryogenesis time at different temperatures was similar for them all. D. mojavensis, a sub-tropical fly, develops slower than the tropical species at lower temperatures, while D. virilis, a temperate fly, exhibits slower development at all temperatures. The alpine sister species D. persimilis and D. pseudoobscura develop as rapidly as tropical flies at cooler temperatures, but exhibit diminished acceleration above 22.5°C and have drastically slowed development by 30°C. Despite ranging from 13 hours for D. erecta at 30°C to 46 hours for D. virilis at 17.5°C, the relative timing of events from cellularization through hatching is constant across all species and temperatures examined here, suggesting the existence of a previously unrecognized timer controlling the progress of embryogenesis that has been tuned by natural selection as each species diverges.
Data from: Genetic uniformity and long-distance clonal dispersal in the invasive androgenetic Corbicula clams
The clam genus Corbicula is an interesting model system to study the evolution of reproductive modes since it includes both sexual and asexual (androgenetic) lineages. While the sexual populations are restricted to the native Asian areas, the androgenetic lineages are widely distributed being also found in America and Europe where they form a major aquatic invasive pest. We investigated the genetic diversity of native and invasive Corbicula populations through a worldwide sampling. The use of mitochondrial and nuclear (microsatellite) markers revealed an extremely low diversity in the invasive populations with only four, undiversified, genetic lineages distributed across Europe and America. On the contrary, in the native populations, both sexual and androgenetic lineages exhibited much higher genetic diversity. Remarkably the most abundant and widely distributed invasive forms, the so-called form A and form R found in America and Europe respectively, are fixed for the same single COI (cytochrome c oxydase subunit I) haplotype and same multilocus genotype. This suggests that form R, observed in Europe since the 1980s, derived directly from form A found in America since the 1920s. In addition, this form shares alleles with some Japanese populations indicating a Japanese origin for this invasive lineage. Finally, our study suggests that few androgenetic Corbicula individuals successfully invaded the non-native range and then dispersed clonally. This is one striking case of genetic paradox raising the issue of invasive and evolutionary success of genetically undiversified populations.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.