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1,395
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Dataset results
1,395 results for “Tumor immunity”
Tumor-Host Signaling Interaction Reveals a Systemic, Age-Dependent Splenic Immune Influence on Tumor Development
GEO Series GSE73451. Mus musculus. 72 samples. Type: Expression profiling by array.
Human CD4 cytotoxic T lymphocytes mediate potent tumor control via tumor cell HLA 2 class II expression in a humanized immune system mouse model
GEO Series GSE223026. Homo sapiens; Mus musculus. 22 samples. Type: Expression profiling by high throughput sequencing.
Single-cell screens identify ADAM12 as a fibroblast checkpoint impeding anti-tumor immunity - scRNA-seq of co-injection murine models
GEO Series GSE278975. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing.
Media based off the metabolome of tumor interstitial fluid reveals metabolic checkpoints and novel oncometabolites in cancer immunity
GEO Series GSE235214. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing.
The effect on cancer cells of the glycodendrimers believed to decrease tumor growth, prolong survival time, and enhance immune response
GEO Series GSE29936. Homo sapiens. 18 samples. Type: Expression profiling by array.
Bacterial immunotherapy leveraging IL-10R hysteresis for both phagocytosis evasion and tumor immunity revitalization [ATAC-seq]
GEO Series GSE284218. Homo sapiens. 8 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
The processed data of a landscape of immune microenvironment for Solid Tumors
<h3>This study provides a comprehensive and detailed atlas of the immune microenvironment for solid tumors. The dataset includes processed single-cell sequencing data from 25 types of solid tumors and 3 normal tissues.</h3>
Pembrolizumab alters the tumor immune landscape in a patient with dMMR glioblastoma
<p>Congenital DNA mismatch repair defects (dMMR), such as Lynch Syndrome, predispose patients to a variety of cancers and account for approximately 1% of glioblastoma cases. While few therapeutic options exist for glioblastoma, checkpoint blockade therapy has proven effective in dMMR tumors. Here we present a case study of a male in his 30s diagnosed with dMMR glioblastoma treated with pembrolizumab who experienced a partial response to therapy. Using a multiplex IHC analysis pipeline on archived slide specimens taken upon tumor resection at diagnosis and after therapeutic intervention, we quantified changes in the frequency and spatial distribution of key immune and tumor cell populations in the tissue. Notably, proliferating KI67+ macrophages and T cells increased in frequency as did KI67+ tumor cells. Therapeutic intervention remodeled the cellular spatial distribution in the tumor leading to a greater frequency of macrophage/tumor cell interactions and T cell/T cell interactions, highlighting the impact of checkpoint blockade on tumor cytoarchitecture and revealing spatial patterns indicative of advantageous immune interactions in glioma and other solid tumors treated with these agents.</p> <p>This dataset includes serial multiplex IHC staining with CD3, CD8, CD4, IBA1, CD68, PD-1, PD-L1, KI67, hematoxylin (HEMA), and H&E (HNE) performed on 3 difference tumor tissue samples taken from a patient with Lynch Syndrome Associated glioblastoma.</p> <p>N20-11-2E = 1st Resection</p> <p>S21-030818-B1-6 = 2nd Resection</p> <p>S21-15696-A1(35) = 3rd Resection</p>
Source data - Langerhans islets induce CCL27-driven anti-tumor immunity at the expense of glycemic control and predict chemotherapy response in pancreatic cancer
Open the record for dataset details and reuse information.
KDM5A epigenetically orchestrates MHC-I associated anti-tumor immunity of immunotherapy [DC RNA-seq]
GEO Series GSE260912. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.
KDM5A epigenetically orchestrates MHC-I associated anti-tumor immunity of immunotherapy [DC-CUTTag]
GEO Series GSE256048. Mus musculus. 2 samples. Type: Other.
KDM5A epigenetically orchestrates MHC-I associated anti-tumor immunity of immunotherapy [tumor-CUTTag]
GEO Series GSE256056. Mus musculus. 3 samples. Type: Other.
9-PAHSA orchestrates TCR-T cell fate to boost anti-tumor immunity [ATAC-seq]
GEO Series GSE315178. Mus musculus. 8 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
9-PAHSA orchestrates TCR-T cell fate to boost anti-tumor immunity
GEO Series GSE315828. Mus musculus. 10 samples. Type: Expression profiling by high throughput sequencing.
KDM5A epigenetically orchestrates MHC-I associated anti-tumor immunity of immunotherapy
GEO Series GSE256057. Mus musculus. 9 samples. Type: Other.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.