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2,031
datasets available to search
ShareScore release 0.9.0
Dataset results
2,031 results for “transformation”
SMARCB1 regulates a TFCP2L1-MYC transcriptional switch promoting renal medullary carcinoma transformation and ferroptosis resistance. [ChIPseq and Cut&Tag]
GEO Series GSE180998. Homo sapiens. 18 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Comparison of diploid and transformed tetraploid MEF cells: gene expression and DNA methylation profiling
GEO Series GSE18815. Mus musculus. 8 samples. Type: Expression profiling by array; Methylation profiling by genome tiling array.
Transcriptom analysis of MCF10A before and after H-RAS transformation [RNA-seq]
GEO Series GSE140253. Homo sapiens. 10 samples. Type: Expression profiling by high throughput sequencing.
Dysregulation of MITF in the context of defective MC1R and RB1/p16/CDK4 leads to melanocyte transformation [microarray]
GEO Series GSE142012. Homo sapiens. 4 samples. Type: Expression profiling by array.
Lipoic acid prevents Cr6+ induced cell transformation and the associated genomic dysregulation.
GEO Series GSE41419. Mus musculus. 3 samples. Type: Expression profiling by array.
Clonal biases dictate availability of colonic cancer driver mutations for transformation
GEO Series GSE312204. Homo sapiens. 20 samples. Type: Other.
Combined mutation of C/EBPa and GATA-2 induce bi-lineage acute erythroid leukemia through transformation of a neomorphic neutrophil-erythroid progenitor [ATAC-seq]
GEO Series GSE141812. Mus musculus. 14 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
ALK–transformed mature T lymphocytes restores early thymus progenitor features
GEO Series GSE160123. Homo sapiens. 5 samples. Type: Expression profiling by high throughput sequencing.
DNA methylation patterns separate senescence from malignant transformation potential in human cells
GEO Series GSE91071. Homo sapiens. 39 samples. Type: Expression profiling by array; Methylation profiling by array.
Smc3 regulates B-cell transit through germinal centers and restricts their malignant transformation (RNA-seq)
GEO Series GSE146754. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Retinoic acid inhibits tumor-associated mesenchymal stromal cell transformation in melanoma
GEO Series GSE169145. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
CRISPR-Cas9 screening of KSHV-transformed cells identifies XPO1 as a vulnerable target of cancer cells by inducing p62 SQSTM1-mediated p53 activation in PML bodies
GEO Series GSE125507. Rattus norvegicus. 24 samples. Type: Other.
Myc regulates the lineage commitment of transformed hepatocytes during liver tumorigenesis (RNA-Seq)
GEO Series GSE156744. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing.
Histologic transformation induced by EGFR tyrosine kinase inhibitors
GEO Series GSE274293. Homo sapiens. 4 samples. Type: Expression profiling by high throughput sequencing.
Silica materials effect on Bhas 42 cell transformation
GEO Series GSE133279. Mus musculus. 36 samples. Type: Expression profiling by array.
Processing-Independent CRISPR RNAs Limit Natural Transformation in Neisseria meningitidis
GEO Series GSE44582. Neisseria lactamica 020-06. 2 samples. Type: Expression profiling by high throughput sequencing.
Transformational Tools and Technologies Project
<p>The Transformational Tools and Technologies (TTT) Project advances state-of-the-art computational and experimental tools and technologies that are vital to aviation applications in the six strategic thrusts. The project develops new computer-based tools, computational fluid dynamics models, and associated scientific knowledge that will provide first-of-a-kind capabilities to analyze, understand, and predict aviation concept performance. These revolutionary tools will be applied to accelerate NASA&rsquo;s research and the community&rsquo;s design and introduction of advanced concepts. The Project also explores technologies that are broadly-critical to advancing ARMD strategic outcomes.&nbsp; Such technologies include the understanding of new types of strong and lightweight materials, innovative controls techniques, and experimental methods.&nbsp; TTT also develops improved MDAO and systems analysis tools to enable multi-disciplinary integration. All of these technologies will support and enable concept development and benefits assessment across multiple ARMD programs and disciplines.</p><p>&nbsp;</p><p>The tools and technologies of interest span many disciplines.&nbsp; The Fluid Mechanics Discipline encompasses advanced turbulence modeling, boundary layer transition prediction and modeling, numerical methods, and flow control development and prediction for a wide range of airframe and propulsion system flow problems of interest.&nbsp; Canonical data is developed and used to validate the modeling improvements developed in this discipline.&nbsp; Development of more accurate physics-based methods such as large eddy simulation (LES) is emphasized.</p><p>The Structures and Materials Discipline emphasizes improved multifunctional and high temperature materials for airframe and engine application, as well as modeling and simulation tool development to improve validated first-principles materials and structural modeling.&nbsp; Development of ceramic matrix composite (CMC) materials for high-temperature engine application is of particular emphasis in the discipline.</p><p>The MDAO (Multi-Disciplinary Design, Analysis &amp; Optimization) and Systems Analysis Discipline develops MDAO and aircraft system-level tools to improve integration of discipline-based technologies and enable improved assessment of system-level benefits.&nbsp; An open-source framework is emphasized to better leverage external partners and increase interaction and benefit to the community.</p><p>The Combustion Discipline is developing more accurate physics-based models for complex multi-species reacting flows representative of aircraft engine combustors.&nbsp; This is done through a combination of high-fidelity benchmark experiments and the use of advanced unsteady turbulence modeling and large eddy simulation (LES) methods.&nbsp; Advanced concepts such as active combustion control and pressure-gain combustion cycles are also investigated.</p><p>The Controls Discipline encompasses work across aircraft flight controls and advanced propulsion controls.&nbsp; Development of technologies to enable distributed engine control systems are an area of emphasis in this discipline.</p><p>The Innovative Measurements Discipline conducts research to advance the state-of-the-art in cross-cutting sensing and measurement technologies for aircraft and propulsion systems.&nbsp; Areas of development include advanced optical measurements, enhanced sensing, and improved data acquisition.</p>
Lagrangian Transport and Transformation Experiment (LaTTE)
Measurements made off the New Jersey coast under the Lagrangian Transport and Transformation Experiment (LaTTE) in 2004 and 2005.
NOTCH3 knockdown in non-transformed human esophageal cells
GEO Series GSE27424. Homo sapiens. 12 samples. Type: Expression profiling by array.
Digital transformation of herbal medicine: Conversion to biological entity data using tonifying herbal medicine-induced transcriptome sequencing_Tonifying_HT29
GEO Series GSE244694. Homo sapiens. 273 samples. Type: Expression profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.