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231 results for “Avian influenza”
Annual report on surveillance for avian influenza in poultry and wild birds in Member States of the European Union in 2021 – high-quality maps
<p>Here you can find the high-quality maps published in the ‘Annual report on surveillance for avian influenza in poultry and wild birds in Member States of the European Union in 2021' by EFSA.</p>
Data from: Inferring epidemiologic dynamics from viral evolution: 2014–2015 Eurasian/North American highly pathogenic avian influenza viruses exceed transmission threshold, R0 = 1, in wild birds and poultry in North America
Highly pathogenic avian influenza virus (HPAIV) is a multi-host pathogen with lineages that pose health risks for domestic birds, wild birds, and humans. One mechanism of intercontinental HPAIV spread is through wild bird reservoirs and wild birds were the likely sources of a Eurasian (EA) lineage HPAIV into North America in 2014. The introduction resulted in several reassortment events with North American (NA) lineage low pathogenic avian influenza viruses and the reassortant EA/NA H5N2 went on to cause one of the largest HPAIV poultry outbreaks in North America. We evaluated three hypotheses about novel HPAIV introduced into wild and domestic bird hosts: (i) transmission of novel HPAIVs in wild birds was restricted by mechanisms associated with highly-pathogenic phenotypes; (ii) the HPAIV poultry outbreak was not self-sustaining and required viral input from wild birds; (iii) reassortment of the EA H5N8 generated reassortant EA/NA AIVs with a fitness advantage over fully Eurasian lineages in North American wild birds. We used a time-rooted phylodynamic model that explicitly incorporated viral population dynamics with evolutionary dynamics to estimate the basic reproductive number (R0) and viral migration among host types in domestic and wild birds, as well as between the EA H5N8 and EA/NA H5N2 in wild birds. We did not find evidence to support hypothesis (i) or (ii) as our estimates of the transmission parameters suggested that the HPAIV outbreak met or exceeded the threshold for persistence in wild birds (R0 > 1) and poultry (R0 ≈ 1) with minimal estimated transmission among host types. There was also no evidence to support hypothesis (iii) because R0 values were similar among EA H5N8 and EA/NA H5N2 in wild birds. Our results suggest that this novel HPAIV and reassortments did not encounter any transmission barriers sufficient to prevent persistence when introduced to wild or domestic birds.
Data from: Molecular analysis of H7 avian influenza viruses from Australia and New Zealand: genetic diversity and relationships from 1976 to 2007
Full genome sequencing of 11 Australian and one New Zealand subtype H7 avian influenza A isolates has enabled the comparison of sequences from each of the genome segments to other sequenced subtype H7 avian influenza A. The inference of phylogenetic relationships for each segment has been used to develop a model of the natural history of these viruses in Australia. The Australian H7 hemagglutinins form a monophyletic clade, consistent with the long-term, independent evolution due to geographic isolation. Based on the analysis of the other available H7 hemagglutinins sequences, the three other geographic regions for which similar monophyletic clades have been observed were confirmed; these regions are Eurasia (Africa, Europe and Asia), North America and South America. Analysis of datasets of H7N1, H7N3, H7N7 neuraminidase sequences revealed congruent relationships indicating a similar pattern of geographically constrained independent evolution for each of the neuraminidase subtype datasets. This pattern of evolution in geographic isolation is supported by analysis of each of the six remaining segments of the Australian isolates. These data in combination with the occurrence of five different combinations of neuraminidase subtypes (H7N2, H7N3, H7N4, H7N6, H7N7) among the 11 Australian isolates suggests a single maintenance network of hosts, probably comprising several avian species, for subtype H7 avian influenza A in Australia. A clear time based evolution of the hemagglutinins sequences despite the occurrence of multiple neuraminidase types suggest a genetic pool from which a variety of reassorants arise rather than the presence of a small number of stable viral clones. This pattern of evolution is likely to occur in each of the regions mentioned above as well as possibly a new region comprising of New Zealand, based on the apparent genetic isolation of the isolate analyzed in this study.
Genetic variation data derived from ferret transmission experiments of avian H3N8 influenza viruses
<p>Supplementary Dataset 1. Genetic variation data derived from ferret transmission experiment of HN/4-10 virus<br> Supplementary Dataset 2. Genetic variation data derived from ferret transmission experiment of CS/1000 virus<br> Supplementary Dataset 3. Genetic variation data derived from ferret transmission experiment of CK/FE12 virus<br> Supplementary Dataset 4. Genetic variation data derived from ferret transmission experiment of CK/F0316 virus</p>
Safety Study of an Oral Vaccine to Prevent Avian Influenza
ClinicalTrials.gov study NCT01335347. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Safety and Immunogenicity of Replication-Competent Adenovirus 4-vectored Vaccine for Avian Influenza H5N1
ClinicalTrials.gov study NCT01006798. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Safety and Immunogenicity of Live Influenza A Vaccine for Avian Influenza H7N7
ClinicalTrials.gov study NCT00922259. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Host Genetic Susceptibility to Avian Influenza A/H5N1
ClinicalTrials.gov study NCT01074736. IPD Sharing: Not stated. Countries: 1. Publications: 56.
Study of Seasonal Influenza Vaccine Against H5N1 Avian Influenza Virus
ClinicalTrials.gov study NCT01044095. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Rechallenge With a Low Pathogenicity Avian H10N7 Influenza Virus in Healthy Human Volunteers Previously Challenged With H10N7 Influenza
ClinicalTrials.gov study NCT07215871. IPD Sharing: NO. Countries: 1. Publications: 3.
Low Pathogenicity Avian H10N7 Influenza Virus in a Healthy Human Challenge Model
ClinicalTrials.gov study NCT05436444. IPD Sharing: NO. Countries: 1. Publications: 3.
Data from: Molecular analysis of H7 avian influenza viruses from Australia and New Zealand: genetic diversity and relationships from 1976 to 2007
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Data from: Long-term avian influenza virus epidemiology in a small Spanish wetland ecosystem is driven by the breeding Anseriformes community
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Data from: Reassortment patterns of avian influenza virus internal segments among different subtypes
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Data from: Inferring epidemiologic dynamics from viral evolution: 2014–2015 Eurasian/North American highly pathogenic avian influenza viruses exceed transmission threshold, R0 = 1, in wild birds and poultry in North America
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Data from: Human and hunting dog interactions in the united states: Insights into potential Zoonotic disease and highly pathogenic avian influenza virus transmission
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Data from: Transfer of maternal antibodies against avian influenza virus in mallards (Anas platyrhynchos)
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Data from: Intercontinental genetic structure and gene flow in Dunlin (Calidris alpina), a potential vector of avian influenza
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Data from: The ecology of avian influenza viruses in wild dabbling ducks (Anas spp.) in Canada
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Data from: Adaptive evolution and environmental durability jointly structure phylodynamic patterns in avian influenza viruses
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ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
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DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.