Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
2,322
datasets available to search
ShareScore release 0.9.0
Dataset results
2,322 results for “Circulation”
Dataset for the optimization and validation of a gas chromatography-mass spectrometry method to analyze acetate, propionate and butyrate in the systemic circulation.
<p>This dataset contains data about the optimization and validation of a gas chromatography method to analyze acetate, propionate and butyrate in blood. Validation parameters include linearity, precision, accuracy and recovery. The method's applicability was demonstrated with the analysis of the short-chain fatty acids in human blood samples that were collected in a dietary intervention study.</p>
Data for "Anthropogenic aerosols have significantly weakened the regional summertime circulation in the Northern Hemisphere during the satellite era"
<p>The dataset supporting the conclusion of the submitted paper is uploaded here.</p> <p>The data are labeled after each figure. The npz files include data required to reproduce our results in python arrays.</p> <p> </p>
Southern Ocean's circulation impact on the marine carbon cycle
<p>In the context of past and present climate change, the Southern Ocean (SO) has been identified as a crucial region modulating the concentration of atmospheric CO<sub>2</sub>. The sustained upwelling of carbon-rich deep waters and inefficient nutrient utilisation at the surface of SO leads to an outgassing of natural CO<sub>2</sub>, while anthropogenic CO<sub>2</sub> is entrained to depth during the formation of Antarctic Bottom water (AABW), Antarctic intermediate water (AAIW) and sub-Antarctic mode water (SAMW). Changes to the SO circulation resulting from both dynamic and buoyancy forcing can alter the rate of upwelling as well as formation and subsequent transport of AABW, AAIW and SAMW, thus impacting the air-sea CO<sub>2</sub> exchange in SO. Models of all complexity robustly show that stronger southern hemispheric (SH) westerlies enhance the SO upwelling, thus leading to stronger natural CO<sub>2</sub> outgassing, with a sensitivity of ∼0.13 GtC/yr for a 10% increase in SH westerly windstress. While the impact of changes in the position of the SH westerly winds was previously unclear, recent simulations with high-resolution ocean/sea-ice/carbon cycle models show that a poleward shift of the SH westerlies also enhances natural CO<sub>2</sub> outgassing with a sensitivity of ∼0.08GtC/yr for a 5• poleward shift. While enhanced AABW transport reduces deep ocean natural DIC concentration and increases surface natural DIC concentration, it acts on a centennial timescale. Future work should better constrain both the natural and anthropogenic carbon cycle response to changes in AABW and the compound impacts of dynamic and buoyancy changes on the SO marine carbon cycle.</p>
Comprehensive clinical and genetic analyses of circulating bile acids and their associations with diabetes and its indices
<p>Files containing source data for "Comprehensive clinical and genetic analyses of circulating bile acids and their associations with diabetes and its indices," by Choucair et al., published in <em>Diabetes</em>.</p>
Coronary Circulation Enhances the Aerobic Performance of Pacific Salmon, Particularly for Females
<p>Female Pacific salmon often experience higher mortality than males during their once-in-a-lifetime up-river spawning migration, particularly when exposed to secondary stressors (e.g. high temperatures). However, the underlying mechanisms remain unknown. One hypothesis is that female Pacific salmon hearts are more oxygen-limited than males and are less able to supply oxygen to the body's tissues during this demanding migration. Such oxygen limitations can develop from naturally occurring coronary blockages (<em>i.e.</em>, coronary arteriosclerosis) found in mature salmon hearts. To test this hypothesis, we measured resting (RMR) and maximum metabolic rate (MMR), aerobic scope (AS) and acute upper thermal tolerance in coho salmon (<em>Oncorhynchus kisutch</em>) with an intact or artificially blocked coronary oxygen supply. We also assessed venous blood oxygen and chemistry (cortisol, ions, and metabolite concentrations) at different time intervals during recovery from exhaustive exercise. We found that coronary blockage impaired MMR, but to a greater extent in females than males. Thus, coronary oxygen supply is more important in females than males to support peak metabolism, which is essential during upriver swimming. Furthermore, the coronary blockage reduced AS and PvO<sub>2</sub> during exercise recovery but did not differ between sexes. Coronary ligation lowered acute upper thermal tolerance by 1.1°C. Our findings highlight the importance of coronary blood supply for mature salmon and show evidence that elevated female mortality may be linked to cardiac limitation, particularly during warm water conditions.</p>
Fig. 1 in Circulating dengue virus serotypes and vertical transmission in AEdES larvae during outbreak and inter-outbreak seasons in a high dengue risk area of Sri Lanka
Fig. 1 Map of Sri Lanka showing the location of Mawanella, the study area
Supplementary data for "Seasonal emergence and circulation coupling of moist layers over the tropical Atlantic"
<p>The data provided here contains the derived moist layer characteristics from ERA5 reanalysis, as presented in the associated publication. Data is given on a 0.25° latitude/longitude grid between 30°N/S on the native vertical levels of the ERA5 dataset, cut off at 50 hPa. When a moist layer is detected at a given location and altitude, as identified by the method described in Sect. 2.2 of the publication, the moist layer characteristics (strength, pressure level, upper bound pressure, lower bound pressure) are written in the associated files at the given location (lat/lon) and pressure level of the moist layer. Here, we provide the 15 year means and standard deviations for the months January and July, and the 3 hourly data along the equatorial and 15°N cross-sections of the Atlantic used for the Hovmoller diagrams in Fig. 4 and Supporting Figure S1 of the publication.</p> <p>Files containing "geographical_mean" indicate monthly means on the latitude/longitude grid. Files containing "moisture_space" indicate monthly means within moisture space over the tropical Atlantic, as defined in the paper. <br><br>Code used to generate the data and to conduct the analysis presented in the publication are provided in the github repository URL listed in the Software section.</p>
CXCL12-loaded-hydrogel (CLG): a new device for metastatic Circulating Tumor Cells (CTCs) capturing and characterization
<p><strong>Background</strong>: Circulating Tumor Cells (CTCs) represent a small, heterogeneous population that comprise the minority of cells able to develop metastasis. To trap and characterize CTCs with metastatic attitude, a CXCL12-loaded hyaluronic-gel (CLG) was developed. CXCR4+cells with invasive capability would infiltrate CLG.<br><strong>Methods</strong>: Human colon, renal, lung and ovarian cancer cells (HT29, A498, H460 and OVCAR8 respectively) were seeded on 150 µl Empty Gels (EG) or 300 ng/ml CXCL12 loaded gel (CLG) and allowed to infiltrate for 16 hours. Gels were then digested and fixed with 2% FA-HAse for human cancer cell enumeration or digested with HAse and cancer cells recovered. CLG-recovered cells migrated toward CXCL12 and were tested for colonies/spheres formation. Moreover, CXCR4, E-Cadherin and Vimentin expression was assessed through flow cytometry and RT-PCR. The clinical trial “TRAP4MET” recruited 48 metastatic/advanced cancer patients (8 OC, 8 LC, 8 GBM, 8 EC, 8 RCC and 8 EC). 10 cc whole blood were devoted to PBMCs extraction (7cc) and ScreenCell™ filters (3cc) CTCs evaluation. Ficoll-isolated patient’s PBMCs were seeded over CLG and allowed to infiltrate for 16 hours; gels were digested and fixed with 2% FA-HAse, cells stained and DAPI+/CD45-/pan-CK+ cells enumerated as CTCs.<br><strong>Results</strong>: Human cancer cells infiltrate CLG more efficiently than EG (CLG/EG ratio 1.25 for HT29/ 1.58 for A498/ 1.71 for H460 and 2.83 for OVCAR8). CLG- recovered HT29 cells display hybrid-mesenchymal features [low E-cadherin (40%) and high vimentin (235%) as compared to HT29], CXCR4 two-fold higher than HT29, efficiently migrate toward CXCL12 (two-fold higher than HT29) and developed higher number of colonies (171±21 for HT29-CLG vs 131±8 colonies for HT29) /larger spheres (spheroid area: 26561±6142 µm2 for HT29-CLG vs 20297±7238 for HT29). In TRAP4MET clinical trial, CLG-CTCs were isolated in 8/8 patients with OC, 6/8 with LC, 6/8 with CRC, 8/8 with EC, 8/8 with RCC cancer and 5/8 with GBM. Interestingly, in OC, LC and GBM, CLG isolated higher number of CTCs as compared to the conventional ScreenCell™ (CLG/SC ratio=1.88 for OC, 2.47 for LC and 11.89 for GBM). Bland and Altman blot analysis and Passing and Bablok regression analysis showed concordance between the methodological approaches but indicate that SC and CLG are not superimposable suggesting that the two systems select cells with different features.<br><strong>Conclusion</strong>: CLG might represent a new and easy tool to isolate invasive CTCs in multiple cancers such as OC, LC and GBM at today orphan of reliable methods to consistently detect CTCs. </p>
Figure 1 in Genetic structure of Trypanosoma congolense "forest type" circulating in domestic animals and tsetse flies in the South-West region of Cameroon
Figure 1. Allelic frequency at each locus by host.
Data for: Influence of Anomalous Ocean Heat Transport on the Extratropical Atmospheric Circulation in a High-Resolution Slab-Ocean Coupled Model
<p>This dataset, provided in NetCDF format, supports the research presented in the paper titled "Influence of Anomalous Ocean Heat Transport on the Extratropical Atmospheric Circulation in a High-Resolution Slab-Ocean Coupled Model." Please contact Dr. Sun (ltsun@rams.colostate.edu) if you have any questions.</p>
Fig. 2 in Trichinella species circulating in wild boar (Sus scrofa) populations in Poland
Fig. 2. Geographical distribution of Trichinella species occurs in wild boar populations in Poland.
Sequence feature comparison between xenomiRs and mobile miRNA, and xenomiRs and circulating miRNA
<p>Sequence feature comparison between xenomiRs and mobile miRNA, and xenomiRs and circulating miRNA. Bold indicates the mean of that feature in xenomiR is larger.</p>
Model outputs for: "Disentangling the Local Circulations over a Region with Complex Physiography in the Eastern Amazon: A Modeling Approach"
<p>This repository contains all publicly available numerical simulations related to the paper: Disentangling the Local Circulations over a Region with Complex Physiography in the Eastern Amazon: A Modeling Approach</p>
Enumeration of Circulant Best Matrices
<p>These files contain an enumeration of all inequivalent defining rows of circulant best matrices up to order 57. The row entries are encoded using the characters '+' for 1 and '-' for −1.</p> <p>A <a href="https://uwaterloo.ca/mathcheck/download/best-matrices">table with the sequence counts</a> in each file is also available.</p>
Model outputs for "Multi-grid algorithm for passive tracer transport in NEMO ocean circulation model"
<p>Model outputs used to write "Multi-grid algorithm for passive tracer transport in NEMO ocean circulation model" publication.</p>
Paleobathymetric reconstructions of the SW Barents Seaway and their implications for Atlantic–Arctic ocean circulation
<p>These files are the paleobathymetry and paleotopography reconstructions published in Lasabuda et al., 2023.</p> <p>There are five time slices,</p> <ol> <li>Base Lower Eocene (55 Ma)</li> <li>Base Middle Eocene (47 Ma)</li> <li>Base Oligocene (33 Ma)</li> <li>Base Miocene (23 Ma)</li> <li>Base Quaternary (2.7 Ma)</li> </ol> <p>They are in zmap with coordinate reference system ED50-UTM33.</p> <p> </p> <p>Reference to the article:</p> <p>Lasabuda, A.P.E., Hanssen, A., Laberg, J.S. <em>et al.</em> Paleobathymetric reconstructions of the SW Barents Seaway and their implications for Atlantic–Arctic ocean circulation. <em>Commun Earth Environ</em> <strong>4</strong>, 231 (2023). https://doi.org/10.1038/s43247-023-00899-y</p>
Data for "Summertime Secondary Convection and Interaction with Sea Breeze Circulations"
<p>Datasets for manuscript entitled "Summertime Secondary Convection and Interaction with Sea Breeze Circulations"</p>
Shift in Circulating Human Adenovirus Species Leading to Nationwide Outbreak - China, January 2023-August 2024
<p><span>The list of pathogens detected by the tNGS used in this study</span></p>
Table 2 in Circulating dengue virus serotypes and vertical transmission in AEdES larvae during outbreak and inter-outbreak seasons in a high dengue risk area of Sri Lanka
<p><b>Table 2</b> Distribution of DENV serotypes in patients with suspected dengue and in <i>Aedes</i> mosquito larvae</p><table><tbody><tr><th>Patient no.</th><th><i>Ae. aegypti</i></th><th><i>Ae. albopictus</i></th><th>DENV serotype identified in mosquito pools</th><th>DENV serotype identified in patients</th></tr></tbody><tbody><tr><th>1</th><td>Detected</td><td>ND</td><td>DENV-3</td><td>DENV-3</td></tr><tr><th>2</th><td>ND</td><td>Detected</td><td>DENV-1</td><td>DENV-1</td></tr><tr><th>3</th><td>ND</td><td>Detected</td><td>DENV-3</td><td>DENV-3</td></tr><tr><th>4</th><td>ND</td><td>Detected</td><td>DENV-4</td><td>ND</td></tr><tr><th>5</th><td>ND</td><td>Detected</td><td>DENV-3</td><td>ND</td></tr><tr><th>6</th><td>ND</td><td>Detected</td><td>DENV-1</td><td>ND</td></tr><tr><th>7</th><td>Detected</td><td>ND</td><td>DENV-2</td><td>ND</td></tr><tr><th>8</th><td>Detected</td><td>ND</td><td>DENV-1</td><td>ND</td></tr><tr><th>9</th><td>Detected</td><td>ND</td><td>DENV-1</td><td>ND</td></tr><tr><th>10</th><td>ND</td><td>Detected</td><td>DENV-3</td><td>ND</td></tr><tr><th>11</th><td>ND</td><td>Detected</td><td>DENV-2</td><td>ND</td></tr><tr><th>12</th><td>ND</td><td>Detected</td><td>DENV-2</td><td>DENV-1</td></tr><tr><th>13</th><td>ND</td><td>Detected</td><td>DENV-2</td><td>ND</td></tr><tr><th>14</th><td>ND</td><td>Detected</td><td>DENV-4</td><td>ND</td></tr><tr><th>15</th><td>ND</td><td>Detected</td><td>DENV-1</td><td>ND</td></tr><tr><th>16</th><td>ND</td><td>Detected</td><td>DENV-2</td><td>DENV-2</td></tr></tbody></table><p><i>ND</i> Not detected</p>
Table 1 in Circulating dengue virus serotypes and vertical transmission in AEdES larvae during outbreak and inter-outbreak seasons in a high dengue risk area of Sri Lanka
<p><b>Table 1</b> Distribution of <i>Aedes</i> mosquito larvae in and around residences of patients with suspected dengue in Mawanella from December 2015 to March 2017</p><table><tbody><tr><th>Period</th><th>Month and year of sample collection</th><th>Total no. of vector pools collected in entomological survey</th><th>No. of <i>Aedes</i> mosquito pools identified</th></tr><tr><th><i>Ae. aegypti</i></th><th><i>Ae. albopictus</i></th></tr></tbody><tbody><tr><th>Epidemic</th><td>12/2015</td><td>18</td><td>3</td><td>15</td></tr><tr><th></th><td>1/2016</td><td>22</td><td>8</td><td>14</td></tr><tr><th>Inter-epidemic</th><td>2/2016</td><td>5</td><td>0</td><td>5</td></tr><tr><th></th><td>3/2016</td><td>3</td><td>1</td><td>2</td></tr><tr><th></th><td>4/2016</td><td>4</td><td>1</td><td>3</td></tr><tr><th></th><td>5/2016</td><td>12</td><td>1</td><td>11</td></tr><tr><th></th><td>6/2016</td><td>15</td><td>9</td><td>6</td></tr><tr><th>Epidemic</th><td>7/2016</td><td>7</td><td>1</td><td>6</td></tr><tr><th></th><td>8/2016</td><td>5</td><td>2</td><td>3</td></tr><tr><th></th><td>9/2016</td><td>5</td><td>2</td><td>3</td></tr><tr><th>Inter-epidemic</th><td>10/2016</td><td>6</td><td>1</td><td>5</td></tr><tr><th></th><td>11/2016</td><td>6</td><td>1</td><td>5</td></tr><tr><th>Epidemic</th><td>12/2016</td><td>14</td><td>3</td><td>11</td></tr><tr><th></th><td>1/2017</td><td>23</td><td>8</td><td>15</td></tr><tr><th>Inter-epidemic</th><td>2/2017</td><td>1</td><td>0</td><td>1</td></tr><tr><th></th><td>3/2017</td><td>25</td><td>8</td><td>17</td></tr><tr><th>Total</th><td></td><td>171</td><td>49</td><td>122</td></tr></tbody></table>
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.