Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
316
datasets available to search
ShareScore release 0.9.0
Dataset results
316 results for “Drug Target”
Systems immunology-based drug repurposing framework to target inflammation in atherosclerosis [Tissue_RNA-seq]
GEO Series GSE230216. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Identification of MUC1-C Dependence in Drug-Resistant Advanced Prostate Cancer Uncovers a New Target for Antibody-Drug Conjugate Therapy
GEO Series GSE276750. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Multiscale drug screening for cardiac fibrosis identifies MD2 as a therapeutic target
GEO Series GSE276445. Homo sapiens. 18 samples. Type: Expression profiling by high throughput sequencing.
Mechanistic study of Wee1 kinase inhibition with AZD1775 exposes drug targetable vulnerabilities in acute B-lymphoblastic leukemia [scATAC-seq]
GEO Series GSE218805. Homo sapiens. 2 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Mechanistic study of Wee1 kinase inhibition with AZD1775 exposes drug targetable vulnerabilities in acute B-lymphoblastic leukemia
GEO Series GSE220114. Homo sapiens. 57 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Other.
Epigenetic drugs selectively target a population of AML cells which are positive for CD123 cell surface markers and are chemoresistant
GEO Series GSE114649. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Drug screen combining RNA landscape analysis reveals targetable pathways in HIV-1 reactivation
GEO Series GSE149353. Homo sapiens. 45 samples. Type: Expression profiling by high throughput sequencing; Other.
A preclinical platform for assessing anti-tumor effects and systemic toxicities of cancer drug targets
GEO Series GSE196783. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Targeting glioblastoma with a brain penetrant drug that impairs brain tumour stem cells via NLE1-Notch1 complex
GEO Series GSE261132. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
High-content, targeted RNA-seq screening in organoids for drug discovery in colorectal cancer
GEO Series GSE157167. Mus musculus. 1249 samples. Type: Expression profiling by high throughput sequencing.
A panel of hepatocellular carcinoma cell lines recapitulates the molecular subtypes of the human disease: A model for targeted drug development
GEO Series GSE35818. Homo sapiens. 20 samples. Type: Expression profiling by array.
Single-cell transcriptomics of NRAS-mutated melanoma transitioning to drug resistance: elevated P2RX7 levels indicate response to targeted therapy
GEO Series GSE230538. Homo sapiens. 16 samples. Type: Expression profiling by high throughput sequencing.
Development of antibody-drug conjugates targeting L1CAM to treat metastatic cancer
GEO Series GSE307811. Homo sapiens. 1 samples. Type: Expression profiling by high throughput sequencing.
Drug Repurposing Using Molecular Network Analysis Identifies Janus Kinase as Targetable Driver in Necrobiosis Lipoidica
GEO Series GSE267132. Homo sapiens. 22 samples. Type: Expression profiling by high throughput sequencing.
A human organoid drug screen identifies α2-adrenergic receptor signaling as a therapeutic target for cartilage regeneration
GEO Series GSE271815. Homo sapiens. 22 samples. Type: Expression profiling by high throughput sequencing.
Global Transcriptional Responses to Cisplatin in Dictyostelium discoideum Identify Potential Drug Targets
GEO Series GSE8287. Dictyostelium discoideum. 100 samples. Type: Expression profiling by array.
Chromasome accessibility profiles at single cell level of Drug-tolerant persister cells induced by targeted therapy in lung adenocarcinoma.
GEO Series GSE275305. Homo sapiens. 10 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
A human organoid drug screen identifies α2-adrenergic receptor signaling as a therapeutic target for cartilage regeneration [bulk RNA-seq]
GEO Series GSE249229. Homo sapiens. 18 samples. Type: Expression profiling by high throughput sequencing.
Dissecting the functional reprogramming and drug targets of the microenvironment in bone marrow fibrosis by single cell mapping
GEO Series GSE156644. Homo sapiens; Mus musculus. 16 samples. Type: Expression profiling by high throughput sequencing.
A Novel Alzheimer's Disease Drug Candidate Targeting Inflammation and Fatty Acid Metabolism
GEO Series GSE93678. Mus musculus. 13 samples. Type: Expression profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.