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207
datasets available to search
ShareScore release 0.7.1
Dataset results
207 results for “Huntingtin”
Mutant huntingtin stalls ribosomes and represses protein synthesis in a cellular model of Huntington disease [Ribo-seq]
GEO Series GSE146674. Mus musculus. 9 samples. Type: Other.
RNA-sequencing of Drosophila expressing mutant Huntingtin in neurons or glia
GEO Series GSE157287. Drosophila melanogaster. 72 samples. Type: Expression profiling by high throughput sequencing.
Mechanism suppressing H3K9 trimethylation in pluripotent stem cells and its demise by polyQ-expanded huntingtin mutations [RNA-seq]
GEO Series GSE118088. Homo sapiens. 19 samples. Type: Expression profiling by high throughput sequencing.
Peripheral huntingtin silencing does not ameliorate central signs of disease in the B6.HttQ111/+ mouse model of Huntington’s disease
GEO Series GSE97101. Mus musculus. 35 samples. Type: Expression profiling by high throughput sequencing.
N17 Modifies Mutant Huntingtin Nuclear Pathogenesis and Severity of Disease in HD BAC Transgenic Mice
GEO Series GSE64386. Mus musculus. 48 samples. Type: Expression profiling by array.
Mono and biallelic inactivation of Huntingtin gene in patient-specific iPS cells reveal HTT roles in striatal development and in neuronal functions impaired in Huntington’s disease
GEO Series GSE228254. Homo sapiens. 31 samples. Type: Expression profiling by high throughput sequencing.
Elucidating a normal function of huntingtin by analysis of huntingtin-null mouse embryonic fibroblasts
GEO Series GSE11139. Mus musculus. 12 samples. Type: Expression profiling by array.
Cynomolgus macaques treated with Divalent-siRNA (Di-siRNA) targeting Huntingtin gene
GEO Series GSE130132. Macaca fascicularis. 24 samples. Type: Expression profiling by high throughput sequencing.
Intersecting impact of CAG repeat and Huntingtin knockout in stem cell-derived cortical neurons
GEO Series GSE284565. Homo sapiens. 15 samples. Type: Expression profiling by high throughput sequencing.
The role of Twist1 in mutant huntingtin-induced transcriptional alterations
GEO Series GSE115523. Mus musculus. 16 samples. Type: Expression profiling by high throughput sequencing.
Sequencing-Guided Design of Genetically Encoded Small RNAs Targeting CAG Repeats for Selective Inhibition of Mutant Huntingtin [II]
GEO Series GSE264218. Homo sapiens. 18 samples. Type: Expression profiling by high throughput sequencing.
The striatal kinase DCLK3 produces neuroprotection against mutant huntingtin
GEO Series GSE104091. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
Astrocyte molecular signatures during Huntington’s disease progression and following huntingtin lowering with zinc finger protein transcriptional repressors
GEO Series GSE124846. Mus musculus. 96 samples. Type: Expression profiling by high throughput sequencing.
Huntingtin is an RNA binding protein and participates in NEAT1-mediated paraspeckles
GEO Series GSE267435. Homo sapiens. 30 samples. Type: Other.
Mutant huntingtin stalls ribosomes and represses protein synthesis in a cellular model of Huntington disease [RNA-seq]
GEO Series GSE146673. Mus musculus. 9 samples. Type: Expression profiling by high throughput sequencing.
Huntingtin aggregation impairs autophagy leading to Argonaute-2 accumulation and global microRNA dysregulation
GEO Series GSE78928. Homo sapiens; Mus musculus. 30 samples. Type: Expression profiling by high throughput sequencing; Non-coding RNA profiling by high throughput sequencing.
In vivo cell-autonomous transcriptional abnormalities revealed in mice expressing mutant huntingtin in striatal but not cortical neurons
GEO Series GSE25232. Mus musculus. 7 samples. Type: Expression profiling by array.
Cell Type-Specific Transcriptomics Reveals that Mutant Huntingtin Leads to Mitochondrial RNA Release and Neuronal Innate Immune Activation
GEO Series GSE152058. Mus musculus; Homo sapiens. 333 samples. Type: Expression profiling by high throughput sequencing.
Truncation of mutant huntingtin in knock-in mice via CRISPR-Cas9 uncovers exon1 huntingtin as a key pathogenic form
GEO Series GSE145879. Mus musculus. 19 samples. Type: Expression profiling by high throughput sequencing.
SUMO-targeted ubiquitin ligases (STUbLs) reduce the toxicity and abnormal transcriptional activity associated with a mutant, aggregation-prone fragment of huntingtin
GEO Series GSE115990. Saccharomyces cerevisiae. 11 samples. Type: Expression profiling by high throughput sequencing.
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.