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308 results for “Individual variation”
Mouse spontaneous behavior reflects individual variation rather than estrous state
<p>Repository containing datasets obtained for Levy et al. 2023, available online here: https://doi.org/10.1016/j.cub.2023.02.035</p> <p>Github link to related analysis code: <a href="https://github.com/dattalab/spontaneous-behavior-reflects-individuality-not-estrous">https://github.com/dattalab/spontaneous-behavior-reflects-individuality-not-estrous</a></p> <p><strong>Abstract</strong></p> <p>Behavior is shaped by both the internal state of an animal and its individual behavioral biases. Rhythmic variation in gonadal hormones during the estrous cycle is a defining feature of female internal state, one that regulates many aspects of sociosexual behavior. However, it remains unclear whether estrous state influences spontaneous behavior, and if so how these effects might relate to individual behavioral variation. Here we address this question by longitudinally characterizing the open field behavior of female mice across different phases of the estrous cycle, using unsupervised machine learning to decompose spontaneous behavior into its constituent elements1-4. We find that each female mouse exhibits a characteristic pattern of exploration that uniquely identifies it as an individual across many experimental sessions; in contrast, estrous state only negligibly impacts behavior, despite its known effects on neural circuits that regulate action selection and movement. Like female mice, male mice exhibit individual specific patterns of behavior in the open field; however, the exploratory behavior of males is significantly more variable than that expressed by females both within and across individuals. These findings suggest an underlying functional stability to the circuits that support exploration in female mice, reveal a surprising degree of specificity in individual behavior, and provide empirical support for the inclusion of both sexes in experiments querying spontaneous behaviors.</p> <p><strong>Behavioral DataFrames:</strong> holds the behavioral syllable data used for the analysis described in the manuscript:</p> <ul> <li>mean_df_female / scalar_df_female - main female dataset</li> <li>mean_df_male / scalar_df_male - main male dataset</li> <li>mean_df_female_control / mean_df_male_control - datasets for male/female control experiment presented in Fig S3.</li> </ul> <p><strong>Model files:</strong></p> <p>Additional MoSeq model files used for generating FigS2A and FigS2H. </p>
Data from: Individual contribution to niche expansion in amphibians: A test of the niche variation hypothesis
<p>The niche variation hypothesis (NVH) suggests that populations released from competition are able to expand their realized ecological niche (Van valen 1965; Bolnick et al. 2007). This increase in total niche width (TNW) can arise by i) increasing heterogeneity among individuals' niche through individual specialization, i.e. inter-individual variation in resource use, (IS – Bolnick et al., 2002; 2003) occurring when different individuals of a population use a subset of the population's resource pool, or ii) by expanding the niche of all individuals within the population (Bolnick et al. 2007). Although several morphological and phenotypical studies have confuted the NVH (e.g. Meiri et al. 2005), there is generally strong support for this hypothesis when behavioural or ecological traits are considered, and in particular when the trophic niche is measured at the individual level (Bolnick et al. 2007; Maldonado et al., 2017). In this study our primary aim is to corroborate the NVH, providing robust evidence for a significant and positive relationship between population TNW and IS in amphibian populations, at a global scale.</p>
Inter-individual Variation in the Blood Pressure Lowering Effects of Dietary Nitrate
ClinicalTrials.gov study NCT05514821. IPD Sharing: YES. Countries: 1. Publications: 1.
Inter Individual Variation in Weight Loss Response to Exercise
ClinicalTrials.gov study NCT00773214. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Anatomical Variation of Cerebral Venous Sinus in Healthy Individuals
ClinicalTrials.gov study NCT05413837. IPD Sharing: NO. Countries: 1. Publications: 1.
Individual variation in age-dependent reproduction: fast explorers live fast but senesce young?
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Data from: Leaf form evolution in Viburnum parallels variation within individual plants
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Data from: Individual variation in parental care reaction norms: integration of personality and plasticity
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Individual-level leaf trait variation and correlation across biological and spatial scales
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Data from: Subtle individual variation in indeterminate growth leads to major variation in survival and lifetime reproductive output in a long-lived reptile
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Data from: The index case is not enough: variation among individuals, groups, and social networks modify bacterial transmission dynamics
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Data from: Individual variation in winter supplementary food consumption and its consequences for reproduction in wild birds.
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Data from: Individual variation in male reproductive behaviour is linked to temporal heterogeneity in predation risk
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Data from: Individual variation in parental workload and breeding productivity in female European starlings: is the effort worth it?
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Data from: Variation in individual temperature preferences, not behavioural fever, affects susceptibility to chytridiomycosis in amphibians
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Data from: Individual contribution to niche expansion in amphibians: A test of the niche variation hypothesis
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Data from: A case for considering individual variation in diel activity patterns
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Data from: Nineteen years of consistently positive and strong female mate preferences despite individual variation
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Data from: Individual niche trajectories drive fitness variation
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Data from: Impact of diet and individual variation on intestinal microbiota composition and fermentation products in obese men
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.