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427 results for “Modularity”

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zenodo32/100

Design of Modular Autoproteolytic Gene Switches Responsive to Anti-Coronavirus Drug Candidates

<p>Data underlying the figures in the publication &ldquo;Design of modular autoproteolytic gene switches responsive to anti-coronavirus drug candidates&rdquo;, published in <em>Nat. Commun.</em>, <strong>2021</strong>, 12, 6786.</p> <p><a href="https://doi.org/10.1038/s41467-021-27072-3">https://doi.org/10.1038/s41467-021-27072-3</a></p> <p>&nbsp;</p> <p>Table of contents:</p> <p><strong>1. Supplementary Information.pdf</strong>: Document containing the Supplementary Tables 1-7 and the Supplementary Figures 1-10.</p> <p><strong>2. Dataset 1</strong>: Raw data points used to create the main and supplementary figures of the paper arranged in worksheets panel by panel.</p> <p>&nbsp;</p> <p>Data availability</p> <p>Sequence data of plasmids encoding PLpro-TAGS and Mpro-TAGS have been deposited in GenBank under accession codes OK425851, OK425852, and OK425853. Original plasmids are available upon request. All vector information is provided in Supplementary Table 4. Detailed statistical analysis is provided in Supplementary Table 7. Source data is provided in the Source data file. Source data are provided with this paper.</p>

opencc-by-4.0Jan 2022View details →
zenodo32/100

Research Artifacts - An Anomaly-based Approach for Detecting Modularity Violations on Method Placement

<p>This record&nbsp;contains research artifacts of our paper.</p> <p>The description of each file is as follows.</p> <ul> <li>case_study.xlsx: a spreadsheet that contains a list of our detected cases and results of our manual inspection</li> <li>java-large+.tar.gz: a preprocessed dataset used for training our detection model</li> <li>model_parameters.ckpt.gz: trained parameters and a word dictionary of our neural network model</li> <li>src.tar.gz: source code of our neural network model written in Python and a dataset preprocessor written in Java</li> </ul>

opencc-by-4.0Mar 2022View details →
zenodo32/100

Dataset (MATLAB format) from Chen Kang et al (2021) Modularity and robustness of frontal cortex networks. Cell, 184(14):3717-3730.

<p><strong>Summary</strong></p> <p>These experiments simultaneously measure neuronal responses from the two hemispheres of premotor cortex (anterior lateral motor cortex, ALM) of adult mice performing pole location discrimination with a short-term memory. We inactivate activity of one hemisphere (left or right) in some trials and both hemispheres in others. Data from 135 recording sessions are included in this release.</p> <p>This dataset contains data from 39 mice (age &gt;&nbsp;P60).&nbsp; 9 VGAT-ChR2-EYFP mice (Jackson laboratory, JAX Stock#014548) and 30 PV-IRES-Cre (JAX Stock#008069) crossed to Rosa26-LSL-ReaChR, red-shifted channelrhodopsin reporter mice (JAX 24846), were used for simultaneous electrophysiology and photoinhibition. The experiments (including experiment methods) are described in the following publication:</p> <p><em>Chen, G., Kang, B., Lindsey, J., Druckmann, S., Li, N. (2021). Modularity and robustness of frontal cortical networks. Cell 184, 1-14. doi: 10.1016/j.cell.2021.05.026</em></p> <p>&nbsp;</p> <p><strong>How to cite the data</strong></p> <p>If you publish any work using the data, please cite the Chen et. al., (2021) publication above and also cite the dataset in the following recommended format:</p> <p>Chen G, Li N (2021); Data and simulations related to: Modularity and robustness of frontal cortical networks. Chen et al (2021) Cell, 184(14):3717-3730.</p> <p><a href="http://dx.doi.org/10.5281/zenodo.6713616">http://dx.doi.org/10.5281/zenodo.6713616</a></p> <p>&nbsp;</p> <p><strong>How to get started</strong></p> <p>Once downloaded</p> <p>1) unzip &ldquo;<strong>analysis_scripts</strong>&rdquo;</p> <p>2) unzip and combine all &quot;<strong>data_structure_*.mat</strong>&quot; and &quot;<strong>meta_data_*.mat</strong>&quot; files into a single folder&nbsp;&ldquo;<strong>datafiles</strong>&rdquo;.</p> <p>&nbsp; &nbsp; &nbsp; &bull; <strong>data_structure_*.mat </strong>- contains raw spike data for one session.</p> <p>&nbsp; &nbsp; &nbsp; &bull; <strong>meta_data_*.mat</strong> - contains the meta data information for one session.</p> <p>&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp;There is one &quot;<strong>meta_data_*.mat</strong>&quot; file for each &quot;<strong>data_structure_*.mat</strong>&quot;</p> <p>3) Run scripts within &quot;<strong>analysis_scripts</strong>&quot;. Follow the instruction in the &quot;<strong>code instruction</strong>&quot;.</p> <p>&nbsp;</p> <p><strong>Data analysis</strong></p> <p>The extracellular recording traces were band-pass filtered (300-6 kHz).&nbsp; Events that exceeded an amplitude threshold (4 standard deviations of the background) were subjected to spike sorting to extract single units. Spike sorting was either manual (Guo et al., 2014b) or using Kilosort2 (https://www.github.com/MouseLand/Kilosort2) (Pachitariu et al., 2016) followed by manually curated with the Phy 2.0 beta 1 GUI (https://github.com/cortex-lab/phy) (Rossant et al., 2016) and manual inspection (Guo et al., 2014a). Spike widths were computed as the trough-to-peak interval in the mean spike waveform.&nbsp; Units with spike width &lt;&nbsp;0.35&nbsp;ms were defined as fast-spiking (FS) neurons and units with spike widths &gt;&nbsp;0.45&nbsp;ms as putative pyramidal neurons. Units with intermediate values (0.35 - 0.45 ms) were excluded.&nbsp; We concentrated our analyses on the putative pyramidal neurons.</p>

opencc-by-4.0Jun 2022View details →
zenodo32/100

Ancient China - Modular Museum HQ

Part of the unity asset - Modular Museum HQ Source: Objaverse 1.0 / Sketchfab

opencc-byJul 2019View details →
zenodo32/100

Rome Modular Kit (Assets/Models)

These are the models used in the game **THE LAST BANQUET IN HERCULANEUM**, developed by me and my colleagues in the Laboratory for Roman Provincial Archaeology at University of Sao Paulo (Brazil): www.larp.mae.usp.br You can download the game here: https://larpmae.itch.io/the-last-banquet-in-herculaneum Source: Objaverse 1.0 / Sketchfab

opencc-by-nc-1.0Sep 2018View details →
zenodo32/100

FREE Low poly India temple wall modular

Texture 4096 x 4096: Color, Normal, Roughness, Ao 5000 poly Source: Objaverse 1.0 / Sketchfab

opencc-byOct 2020View details →
zenodo32/100

Modular Victorian era office Props

Modular Victorian era office Props I made for a school project. Source: Objaverse 1.0 / Sketchfab

opencc-byMar 2021View details →
zenodo32/100

Model configuration and input files for: "CARIB12: A Regional Community Earth System Model / Modular Ocean Model 6 Configuration of the Caribbean Sea"

<p>This collection hosts the configuration and input files to reproduce the regional CESM/MOM6 simulation in: "CARIB12: A Regional Community Earth System Model / Modular Ocean Model 6 Configuration of the Caribbean Sea".&nbsp;<br><br>The initial, open boundary conditions and monthly means for the sponge layers were generated from the GLORYS12V1 reanalysis: <a href="https://doi.org/10.3389/feart.2021.698876">https://doi.org/10.3389/feart.2021.698876</a></p> <p>The tidal amplitudes and phases were generated from the TPXO model: <a href="https://doi.org/10.1175/1520-0426(2002)019&lt;0183:EIMOBO&gt;2.0.CO;2">https://doi.org/10.1175/1520-0426(2002)019&lt;0183:EIMOBO&gt;2.0.CO;2&nbsp;</a></p> <p>The monthly Chlorophyll-a climatology was generated from the SeaWifs mission dataset: <a href="10.5067/ORBVIEW-2/SEAWIFS/L3M/CHL/2018">10.5067/ORBVIEW-2/SEAWIFS/L3M/CHL/2018</a></p> <p>The river runoff to ocean was generated from the GloFAS dataset: <a href="https://doi.org/10.24381/cds.a4fdd6b9">https://doi.org/10.24381/cds.a4fdd6b9&nbsp;</a></p> <p>The topography was generated from the Shuttle Radar Topography Mission: <a href="https://doi.org/10.1029/2019EA000658">https://doi.org/10.1029/2019EA000658</a> and smoothed with a Cressman weighted interpolation scheme.</p> <p>This collection does not include the JRA55-do atmospheric forcing dataset:&nbsp;<a title="Persistent link using digital object identifier" href="https://doi.org/10.1016/j.ocemod.2018.07.002" target="_blank" rel="noreferrer noopener">https://doi.org/10.1016/j.ocemod.2018.07.002</a>&nbsp;</p> <p>Steps to setup a regional configuration of CESM/MOM6 can be found here:&nbsp;<a href="https://github.com/NCAR/regional_cesm_mom6.git">https://github.com/NCAR/regional_cesm_mom6.git</a>&nbsp;</p> <p>&nbsp;</p>

opencc-by-4.0May 2024View details →
zenodo32/100

Model output for: "CARIB12: A Regional Community Earth System Model / Modular Ocean Model 6 Configuration of the Caribbean Sea"

<p>This collection hosts the model output fields used in : "CARIB12: A Regional Community Earth System Model / Modular Ocean Model 6 Configuration of the Caribbean Sea".&nbsp;<br><br>daily_surface_fields.tar: contains daily output of sea surface salinity, surface u and v velocity components, sea-surface height and mixed layer depths. Files are split in two: 2000-01-01:2009-12-31 and 2010-01-01:2019-12-31 as specified by each filename.</p> <p>monthly_3D_tracers.tar: contains monthly mean output of temperature and salinity for the full 3D field (lat,lon,depth). Files are split in two: 2000-01-01:2009-12-31 and 2010-01-01:2019-12-31 as specified by each filename.</p> <p>&nbsp;</p> <p>&nbsp;</p>

opencc-by-4.0May 2024View details →
dryad32/100

Data from: Functional modularity and mechanical stress shape plastic responses during fish development

<p>The adaptive potential of plastic phenotypes relies on combined developmental responses. Here, we investigated how manipulation of developmental conditions related to foraging mode in <em>Megaleporinus macrocephalus</em> fish induces plastic responses at different levels: 1) functional modularity of skull bones, 2) biomechanical properties of the chondrocranium using Finite Element Models, 3) bmp4 expression levels, used as a proxy for molecular pathways involved in bone responses to mechanical load. We identified new modules in the experimental groups, suggesting increased integration in head bone elements associated with the development of subterminal and upturned mouths, which are major features of <em>Megaleporinus </em>plastic morphotypes released in the lab. Plastic responses in head shape involved differences in the magnitude of mechanical stress, which seem restricted to certain chondrocranium regions. Three bones represent a 'mechanical unit' related to changes in mouth position induced by foraging mode, suggesting that functional modularity might be enhanced by specific regions responding to load. Differences in <em>bmp4</em> expression levels between plastic morphotypes indicate associations between molecular signaling pathways and biomechanical responses to load. Our results offer a multilevel perspective of epigenetic factors involved in plastic responses, expanding our knowledge about mechanisms of developmental plasticity that originate novel complex phenotypes.</p>

opencc-zeroJun 2024View details →
zenodo32/100

Data for: Modular environmental and economic assessment applied to the production of Hermetia illucens

Open the record for dataset details and reuse information.

opencc-by-4.0Oct 2021View details →
zenodo32/100

High Definition Modular Multilevel Converter (1st Call for Joint Experiment Final Report and data set)

<p>This project aims to validate experimentally the High definition Modular Multilevel Converter (HD-MMC) which was developed by ORE Catapult. The concept can generate a lower THD than Conventional MMC (C-MMC) helping to increase power density and efficiency. You will find data set and final report here</p>

opencc-by-4.0Nov 2019View details →
zenodo32/100

Symmetric Positive Definite Convolutional Network for Surrogate Modeling and Optimization of Modular Structures

<p>This is the training data for the paper "Symmetric Positive Definite Convolutional Network for Surrogate Modeling and Optimization of Modular Structures"</p>

opencc-by-4.0Apr 2024View details →
zenodo32/100

Artifact for "Modular criticality analysis for dynamic fault trees"

<p>This artifact contains the fault trees and log files of the experimental evaluation from the paper <em>"Modular criticality analysis for dynamic fault trees"</em>. The implementation is available in the <a href="https://www.safest.dgbtek.com/">SAFEST tool</a>.</p>

opencc-by-4.0Nov 2024View details →
zenodo32/100

Extension of Towards Large Scale Automated Algorithm Design by Integrating Modular Benchmarking Frameworks

<p>This provides the dataset and the corresponding parsing scripts that extend the &quot;Towards Large Scale Automated Algorithm Design by Integrating Modular Benchmarking Frameworks&quot; study.</p>

opencc-by-4.0Sep 2021View details →
zenodo32/100

Modular Enantioselective Synthesis of cis-Cyclopropanes through Self-Sensitized Stereoselective Photo-Decarboxylation with Benzothiazolines

<p>Raw data for the characterization of the compounds in the research paper with the same name.</p>

opencc-by-4.0Oct 2021View details →
dryad32/100

Patterns of morphological variation highlight the effect of natural selection on eyespots modularity in the butterfly Morpho telemachus - Dataset

<p>Morphological correlations can stem from developmental constraints but also from selective pressures. Butterfly eyespots are repeated wing color pattern elements, widespread across species. As developmental serial homologues, they are controlled by similar developmental pathways imposing correlations among eyespots: selection on a single eyespot may induce correlated responses in all eyespots. We study the variations in the ventral eyespots of <em>Morpho</em> <em>telemachus</em>, where two different selective regimes are likely to act: while most eyespots are always-visible, two eyespots are conditionally-displayed: hidden at rest, they can be exposed when the butterflies are threatened, or during sexual interactions. We investigate how such contrasted selection across eyespots can alter the covariations imposed by their shared developmental origin. We quantified eyespots' co-variations within a large population of <em>M</em>. <em>telemachus</em> and compared the observed patterns to those found in <em>M</em>. <em>helenor</em>, where all eyespots are always-visible and thus probably affected by a similar selection regime. We found that <em>M</em>. <em>telemachus</em> conditionally-displayed eyespots are less variable than always-visible eyespots and that these two eyespots form a separate variational module in this species, in contrast to <em>M</em>. <em>helenor</em>. Our results suggest that eyespots' covariations were shaped by selection, highlighting how natural selection may promote the evolution of modularity.</p>

opencc-zeroJan 2023View details →
zenodo32/100

Sewer mining modular unit at the Athens Urban Tree Nursery

<p>The Athens Urban Tree Nursery is part of the Goudi Park, an area in the process of redevelopment and regeneration to become the key metropolitan park of the capital. The area, which lies in the heart of Athens, is a mixed-use area, comprising of urban green and urban agriculture spaces as well as administration and residential uses. The regeneration is an effort to boost both the local economy and improve quality of life for the 4.000.000 citizens of the Attica Region.</p> <p>The nursery comprises 4 ha of vegetation, supplys all urban parks and green spaces of Athens with plant material and uses potable water from Athens&rsquo;s Water Supply and Sewerage Company (EYDAP) for its irrigation. The city is seeking alternative water sources leveraging circular economy solutions to achieve environmental, social and financial benefits for the city.</p> <p>The installation of a sewer mining modular unit for urban green irrigation at the point of demand would be of direct benefit for the sustainability of the new metropolitan park. Additionally, compost-based eco-engineered growing media products will be reused as an onsite fertilizer, as part of a portfolio of autonomous, decentralized water, energy and materials circular solutions for cities in water scarce area. Finally, thermal energy recovery schemes will be investigated to minimize the pilot&rsquo;s environmental footprint.</p>

opencc-by-4.0Jan 2023View details →
zenodo32/100

Dataset: On the Stability of a Modular 1000 kV HVDC divider design

<p>In order to calibrate high voltage dividers in testing laboratories and HVDC converter substations, a new measurement infrastructure for on-site calibration up to 1000 kV was established in 2013. A 1000 kV wide-band modular HVDC divider was built divided into stackable 200 kV HV modules for agile on-site assessment, with protection against damage from transients, and for measuring of ripple voltage. Nine 200 kV modules were built by the five NMIs and stacked to one 1000 kV divider and one 800 kV voltage divider. The scale factors of the two dividers were determined in a comparison campaign in June 2013, resulting in a combined expanded uncertainty better than 20 &mu;V/V at 1000 kV, and better than 15 &mu;V/V for 200 kV. Traceability of five modular systems have since been<br> maintained using three methods; where the first method is calibration of the HV resistance of each module and LV arm, calculating the scale factors. The second method uses the Hamon transfer method, applied by RISE with five 200 kV modules. The third method is by comparison of the scale factor which includes the LV arm against a lower voltage reference divider. This paper presents the stability and robustness of all divider systems from June 2013 to spring 2022. The long-term stability is presented for the resistance of both the high voltage and the low voltage arm as well as the scale factor. The result shows an unprecedented stability of a HV divider system.</p>

opencc-by-4.0Dec 2022View details →
zenodo32/100

Dataset:A Modular Universal Divider for Calibration of UHVDC, and Composite Waves up to 1400 KV

<p>With the development of new high voltage cables and switching elements for continuously higher system voltages, especially for HVDC operation, the need for new reference measuring systems for on-site calibration to support activities in type and routine testing. Traceability in testing the fundamental voltage stress, high voltage DC or AC, is superimposed with a Switching or Lightning Impulses has up to now been lacking. This paper describes the design of a new universal RCR divider developed at RISE for a reference measurement system for traceability of ultra-high voltage (UHV) composite and combined waves.</p> <p>In composite/combined wave measurements the RCR divider is rated 500, 330, 600 and 700 kV for DC, AC<sub>rms</sub>, Switching Impulse (SI) and Lightning Impulse (LI) respectively. For UHVDC measurements the extended measurement uncertainty is better than 40 &mu;V/V. In a composite/combined wave measurement, the extended measurement uncertainties for the divider are better than 150 and 400 &mu;V/V for DC and AC and 0.5% for peak voltage of SI and LI. Two voltage dividers have been built for the purpose to measure both composite and combined waves. This divider is modular, where the HV arms can be stacked to 1000, 660, 1200 and 1400 kV and beyond.</p>

opencc-by-4.0Aug 2023View details →

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Allen Brain Atlas

Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.

allen-brain-atlas
neuroscienceopenDocumentation, web resources, and API references are available online.
Last verified 2026-04-30Open record

Annotated Behaviour and Observability Dataset (ABODe)

ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.

abode-home-cage
behavioral-neuroscienceopenThe DataShare record exposes download links for annotations, documentation, license text, and the zipped per-snippet data directory.
Last verified 2026-04-30Open record

DANDI Archive for NWB datasets

DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.

dandi-nwb
electrophysiologyopenPublished Dandiset metadata and archive endpoints are available through the production DANDI API.
Last verified 2026-04-30Open record

International Brain Laboratory public data

The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.

ibl
behavioral-neuroscienceopenPublic sessions can be searched and loaded from the IBL public data server through ONE.
Last verified 2026-04-29Open record

OpenNeuro

OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.

openneuro
neuroscienceopenPublished datasets are available on demand over the internet.
Last verified 2026-04-29Open record