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257
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ShareScore release 0.9.0
Dataset results
257 results for “Proteomic analysis”
Integrated Genetic and Proteomic Analysis Identifies PLK1 as a Candidate Therapeutic Target for SETD2-Deficient Clear Cell Renal Cell Carcinoma
GEO Series GSE107391. Homo sapiens. 14 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Integrinated Omic analysis of lung cancer reveals metabolism proteome signatures with prognostic impact
GEO Series GSE62113. Homo sapiens. 30 samples. Type: Expression profiling by array.
Global genomic and proteomic analysis of TNBC cells identifies the critical role of PELP1 in ribosome biogenesis
GEO Series GSE191066. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Cerebrospinal fluid-derived extracellular vesicles: a proteomic and transcriptomics comparative analysis of enrichment protocols
GEO Series GSE300627. Homo sapiens. 4 samples. Type: Expression profiling by high throughput sequencing.
Characterizing the tumor suppressor activity of FLCN in Birt-Hogg-Dube syndrome through transcriptiomic and proteomic analysis
GEO Series GSE283021. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
Single-cell RNAseq and longitudinal proteomic analysis of a novel semi-spontaneous urothelial cancer model reveals tumor cell heterogeneity and pretumoral urine protein alterations
GEO Series GSE174182. Mus musculus. 7 samples. Type: Expression profiling by high throughput sequencing.
Time-series proteomic analysis of body fluid extracellular vesicles in amyotrophic lateral sclerosis
GEO Series GSE242978. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Global analysis of genome, transcriptome and proteome reveals the response to aneuploidy in human cells
GEO Series GSE39768. Homo sapiens. 18 samples. Type: Expression profiling by array.
Integrated transcriptomics and proteomics analysis reveals muscle metabolism effects of dietary Ulva lactuca and ulvan lyase supplementation in weaned piglets
GEO Series GSE252125. Sus scrofa. 17 samples. Type: Expression profiling by high throughput sequencing.
Proteomic analysis of native hepatocyte nuclear factor-4{alpha} (HNF4{alpha}) isoforms, phosphorylation status, and interactive cofactors.
GEO Series GSE18990. Homo sapiens. 12 samples. Type: Expression profiling by array; Genome binding/occupancy profiling by high throughput sequencing.
Combined analysis of metabolomics, proteomics, and transcriptomics to identify biomarkers for resistant hypertension
GEO Series GSE236442. Homo sapiens. 30 samples. Type: Expression profiling by high throughput sequencing.
Proteomic analysis of murine Piwi proteins reveals a role for arginine methylation in specifying interaction with Tudor family members
GEO Series GSE17319. Mus musculus. 8 samples. Type: Non-coding RNA profiling by high throughput sequencing.
Integrated transcriptomic and proteomic analysis reveals up regulation of apoptosis and small heat shock proteins in lens of rats under low temperature
GEO Series GSE173481. Rattus norvegicus. 10 samples. Type: Expression profiling by high throughput sequencing.
Definition of human cardiac progenitor cell plasma membrane signature: comparative genomic and proteomics analysis with human mesenchymal stem cells
GEO Series GSE84070. Homo sapiens. 9 samples. Type: Expression profiling by high throughput sequencing.
Proteome and secretome analysis reveals differential post-transcriptional regulation of Toll-like receptor responses
GEO Series GSE85448. Mus musculus. 24 samples. Type: Expression profiling by array.
Transcriptomic, proteomic and metabolomic analysis of UV-B signaling in maize
GEO Series GSE25038. Zea mays. 136 samples. Type: Expression profiling by array.
Proteomics Analysis Reveals Differentially Activated Pathways that Operate in Peanut Gynophores at Different Developmental Stages
GEO Series GSE70972. Arachis hypogaea. 3 samples. Type: Expression profiling by high throughput sequencing.
Data from: Exploratory proteomic analysis implicates the alternative complement cascade in Primary CNS Vasculitis
Objective: To identify molecular correlates of primary angiitis of the central nervous system (PACNS) through proteomic analysis of cerebrospinal fluid (CSF) from a biopsy-proven patient cohort. Methods: Using mass spectrometry, the CSF proteome of biopsy-proven PACNS patients (n=8) was quantitatively compared to CSF from individuals with non-inflammatory conditions (n=11). Significantly enriched molecular pathways were identified using a gene ontology workflow, and high confidence hits within enriched pathways (fold change >1.5 and concordant Benjamini-Hochberg-adjusted p-value <0.05 on DeSeq and t-test) were identified as differentially regulated proteins. Results: Compared to non-inflammatory controls, 283 proteins were differentially expressed in PACNS patient CSF, with significant enrichment of the complement cascade pathway (C4-binding protein, CD55, CD59, properdin, complement C5, complement C8 and complement C9) and neural cell adhesion molecules. A subset of clinically relevant findings was validated by western blot and commercial ELISA. Conclusions: In this exploratory study we found evidence of deregulation of the alternative complement cascade in CSF from biopsy-proven PACNS as compared to non-inflammatory controls. More specifically, several regulators of the C3 and C5 convertases and components of the terminal cascade were significantly altered. These preliminary findings shed light on a previously unappreciated similarity between PACNS and systemic vasculitides, especially Anti-Neutrophil Cytoplasmic Antibody (ANCA)-associated vasculitis. The therapeutic implications of this common biology, and the diagnostic and/or therapeutic utility of individual proteomic findings warrant validation in larger cohorts.
Proteomic Analysis of HLA Complex in Solid Cancers: Breast, Ovary, Colon, Rectum, Stomach, and Pancreas
ClinicalTrials.gov study NCT00419627. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Proteomic Analysis Reveals Innate Immune Activity In Intestinal Transplant Dysfunction
ClinicalTrials.gov study NCT01140152. IPD Sharing: Not stated. Countries: 1. Publications: 0.
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.