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156 results for “cardiac magnetic resonance”
Understanding the Metabolic and Functional Derangement of Primary Mitral Regurgitation: a Feasibility Study Using Carbon 11(C-11) Acetate Cardiac Positron Emission Tomography Magnetic Resonance Imagin
ClinicalTrials.gov study NCT04795856. IPD Sharing: NO. Countries: 0. Publications: 0.
Cardiac Magnetic Resonance Features and Outcomes of Patients With Non-Compaction Cardiomyopathy - a Retrospective Follow-up From Pakistan
ClinicalTrials.gov study NCT05281315. IPD Sharing: NO. Countries: 0. Publications: 0.
Cardiac Magnetic Resonance for Diagnosis, Treatment Guidance and Prognosis of Cardiac Masses (CMR)
ClinicalTrials.gov study NCT07335770. IPD Sharing: Not stated. Countries: 0. Publications: 0.
Lipid Rich Necrotic Core Lesion Detected by Cardiac Magnetic Resonance Imaging (CMR)
ClinicalTrials.gov study NCT01284270. IPD Sharing: Not stated. Countries: 0. Publications: 0.
Cardiovascular Magnetic Resonance GUIDEd Insertion of Implantable Cardiac Defibrillator in Dilated CardioMyopathy
ClinicalTrials.gov study NCT03993730. IPD Sharing: NO. Countries: 0. Publications: 0.
Advanced Cardiac Magnetic Resonance Imaging for Assessment of Obstructive Coronary Artery Disease: ADVOCATE-CMR
ClinicalTrials.gov study NCT06419894. IPD Sharing: Not stated. Countries: 0. Publications: 0.
RAW DATA - An accurate and time-efficient deep learning-based system for automated segmentation and reporting of cardiac magnetic resonance-detected ischemic scar - RAW DATA
<p>Raw data (original images, labelled masks) from "An accurate and time-efficient deep learning-based system for automated segmentation and reporting of cardiac magnetic resonance-detected ischemic scar"; https://doi.org/10.1016/j.cmpb.2022.107321</p> <p> </p>
Dataset related to the article " Automated Left and Right Ventricular Chamber Segmentation in Cardiac Magnetic Resonance Images Using Dense Fully Convolutional Neural Network"
<p>This record contains raw data related to the article " Automated left and right ventricular chamber segmentation in cardiac magnetic resonance images using dense fully convolutional neural network"</p> <p><br> Background and objective: Segmentation of the left ventricular (LV) myocardium (Myo) and RV endocardium on cine cardiac magnetic resonance (CMR) images represents an essential step for cardiacfunction evaluation and diagnosis. In order to have a common reference for comparing segmentation algorithms, several CMR image datasets were made available, but in general they do not include the most apical and basal slices, and/or gold standard tracing is limited to only one of the two ventricles, thus not fully corresponding to real clinical practice. Our aim was to develop a deep learning (DL) approach for automated segmentation of both RV and LV chambers from short-axis (SAX) CMR images, reporting separately the performance for basal slices, together with the applied criterion of choice.<br> Method: A retrospectively selected database (DB1) of 210 cine sequences (3 pathology groups) was considered: images (GE, 1.5 T) were acquired at Centro Cardiologico Monzino (Milan, Italy), and end-diastolic (ED) and end-systolic frames (ES) were manually segmented (gold standard, GS). Automatic ED and ES RV and LV segmentation were performed with a U-Net inspired architecture, where skip connections were redesigned introducing dense blocks to alleviate the semantic gap between the U-Net encoder and decoder. The proposed architecture was trained including: A) the basal slices where the Myo surrounded<br> the LV for at least the 50% and all the other slice; B) all the slices where the Myo completely surrounded the LV. To evaluate the clinical relevance of the proposed architecture in a practical use case scenario, a graphical user interface was developed to allow clinicians to revise, and correct when needed, the automatic segmentation. Additionally, to assess generalizability, analysis of CMR images obtained in 12 healthy volunteers (DB2) with different equipment (Siemens, 3T) and settings was performed.<br> Results: The proposed architecture outperformed the original U-Net. Comparing the performance on DB1 between the two criteria, no significant differences were measured when considering all slices together, but were present when only basal slices were examined. Automatic and manually-adjusted segmentation<br> performed similarly compared to the GS (bias±95%LoA): LVEDV -1±12 ml, LVESV -1±14 ml, RVEDV 6±12 ml, RVESV 6±14 ml, ED LV mass 6±26 g, ES LV mass 5±26 g). Also, generalizability showed very similar performance, with Dice scores of 0.944 (LV), 0.908 (RV) and 0.852 (Myo) on DB1, and 0.940 (LV), 0.880 (RV), and 0.856 (Myo) on DB2.<br> Conclusions: Our results support the potential of DL methods for accurate LV and RV contours segmentation and the advantages of dense skip connections in alleviating the semantic gap generated when high level features are concatenated with lower level feature. The evaluation on our dataset, considering separately the performance on basal and apical slices, reveals the potential of DL approaches for fast, accurate and reliable automated cardiac segmentation in a real clinical setting.<br> </p>
Dataset related to the article "CarDiac magnEtic Resonance for prophylactic Implantable-cardioVerter defibrillAtor ThErapy in Non-Ischaemic dilated CardioMyopathy: an international Registry"
<p>This record contains raw data related to the article “CarDiac magnEtic Resonance for prophylactic Implantable-cardioVerter defibrillAtor ThErapy in Non-Ischaemic dilated CardioMyopathy: an international Registry” <br> </p> <p>Abstract</p> <p><strong>Aims: </strong>The aim of this registry was to evaluate the additional prognostic value of a composite cardiac magnetic resonance (CMR)-based risk score over standard-of-care (SOC) evaluation in a large cohort of consecutive unselected non-ischaemic cardiomyopathy (NICM) patients.</p> <p><strong>Methods and results: </strong>In the DERIVATE registry (www.clinicaltrials.gov/registration: RCT<a href="http://clinicaltrials.gov/show/NCT03352648">#NCT03352648</a>), 1000 (derivation cohort) and 508 (validation cohort) NICM patients with chronic heart failure (HF) and left ventricular ejection fraction <50% were included. All-cause mortality and major adverse arrhythmic cardiac events (MAACE) were the primary and secondary endpoints, respectively. During a median follow-up of 959 days, all-cause mortality and MAACE occurred in 72 (7%) and 93 (9%) patients, respectively. Age and >3 segments with midwall fibrosis on late gadolinium enhancement (LGE) were the only independent predictors of all-cause mortality (HR: 1.036, 95% CI: 1.0117-1.056, P < 0.001 and HR: 2.077, 95% CI: 1.211-3.562, P = 0.008, respectively). For MAACE, the independent predictors were male gender, left ventricular end-diastolic volume index by CMR (CMR-LVEDVi), and >3 segments with midwall fibrosis on LGE (HR: 2.131, 95% CI: 1.231-3.690, P = 0.007; HR: 3.161, 95% CI: 1.750-5.709, P < 0.001; and HR: 1.693, 95% CI: 1.084-2.644, P = 0.021, respectively). A composite clinical and CMR-based risk score provided a net reclassification improvement of 63.7% (P < 0.001) for MAACE occurrence when added to the model based on SOC evaluation. These findings were confirmed in the validation cohort.</p> <p><strong>Conclusion: </strong>In a large multicentre, multivendor cohort registry reflecting daily clinical practice in NICM work-up, a composite clinical and CMR-based risk score provides incremental prognostic value beyond SOC evaluation, which may have impact on the indication of implantable cardioverter-defibrillator implantation.</p>
Additional diagnostic value of cardiac magnetic resonance feature tracking in patients with biopsy-proven arrhythmogenic cardiomyopathy
<p>This record contains raw data related to the article “Additional diagnostic value of cardiac magnetic resonance feature tracking in patients with biopsy-proven arrhythmogenic cardiomyopathy”<br> </p> <p>Abstract</p> <p><strong>Background: </strong>We aim to evaluate the value of Cardiac magnetic resonance (CMR) feature tracking (CMR-FT) in addition to Task Force Criteria(TFC) in patients with (arrhythmogenic cardiomyopathy) AC biopsy-proved.</p> <p><strong>Methods: </strong>Thirty-five patients with AC histologically proven who performed CMR with late gadolinium enhancement (LGE) acquisition were enrolled. The study population was divided in Group1 (negative CMR TFC and LV ejection fraction≥55%) and Group2 (positive CMR TFC and/or LVEF<55%) and compared to an age and gender-matched control group. CMR datasets of all patients were analyzed to calculate LV indexed end-diastolic (LVEDi) and end-systolic (LVESi) volumes and RV indexed end-diastolic (RVEDi) and end-systolic (RVESi) volumes, both LV ejection fraction (LVEF) and RV ejection fraction (RVEF). Moreover, LV and RV global longitudinal (GLS), circumferential (GCS) and radial (GRS) strain were measured.</p> <p><strong>Results: </strong>The AC patients showed both higher LVEDi (p:0.002) and RVEDi (p:0.017) and lower LVEF (p: 0.016) as compared to control patients. Moreover, AC patients showed impaired LV-GLS (p < 0.001), LV-GRS (p < 0.001), LV-GCS (p < 0.001) and RV-GRS (p:0.026) as compared to control subjects. Group1 patients showed a significant reduction of LV-GRS (p < 0.05) and LV-GCS p < 0.01) as compared to control subjects. At univariate analysis LV-GCS was the most discriminatory parameter between Group1 vs heathy subjects with an optimal cut-off of -15.8 (Sensitivity: 74%; Specificity: 10%).</p> <p><strong>Conclusions: </strong>In patients with AC biopsy-proven, CMR-FT could improve the diagnostic yield in the subset of patients who results negative for imaging TFC criteria resulting as useful gatekeeper for indication of myocardial biopsy in case of equivocal clinical and imaging presentation.</p> <p> </p>
Brugada Syndrome: New Insights From Cardiac Magnetic Resonance and Electroanatomical Imaging
<p>Dataset from Pappone C, Santinelli V, Mecarocci V, Tondi L, Ciconte G, Manguso F, Sturla F, Vicedomini G, Micaglio E, Anastasia L, Pica S, Camporeale A, Lombardi M. Brugada Syndrome: New Insights From Cardiac Magnetic Resonance and Electroanatomical Imaging. Circ Arrhythm Electrophysiol. 2021 Nov;14(11):e010004. doi: 10.1161/CIRCEP.121.010004. Epub 2021 Oct 25. PMID: 34693720.</p> <p>Abstract</p> <p><strong>Background: </strong>Brugada syndrome (BrS) is considered a purely electrical disease with variable electrical substrates. Variable rates of mechanical abnormalities have been also reported. Whether exists a link between electrical and mechanical abnormalities has never been previously explored. This investigational physiopathological study aimed to determine the relationship between the substrate size/location, as exposed by ajmaline provocation, and the severity of mechanical abnormalities, as assessed by cardiac magnetic resonance in patients with BrS.</p> <p><strong>Methods: </strong>Twenty-four consecutive high-risk patients with BrS (mean age, 38±11 years, 17 males), presenting with malignant syncope and documented polymorphic ventricular tachycardia/ventricular fibrillation, and candidate to implantable cardioverter defibrillator implantation, underwent cardiac magnetic resonance and electroanatomic maps. During each examination, ajmaline test (1 mg/kg over 5 minutes) was performed. Cardiac magnetic resonance findings were compared with 24 age, sex, and body surface area-matched controls. In patients with BrS, the correlation between the electrical substrate extent and right ventricular regional mechanical abnormalities before/after ajmaline challenge was analyzed.</p> <p><strong>Results: </strong>After ajmaline, patients with BrS showed a reduction of right ventricular (RV) ejection fraction (<em>P</em><0.001), associated with decreased transversal displacement (U, <em>P</em><0.001) and longitudinal strain (ε, <em>P</em><0.001) localized at RV outflow tract. In patients with BrS significant preajmaline/postajmaline changes of transversal displacement (ΔU, <em>P</em><0.001) and longitudinal strain (Δε, <em>P</em><0.001) were found. In the control group, no mechanical changes were observed after ajmaline. The electrical substrate consistently increased after ajmaline from 1.7±2.8 cm<sup>2</sup> to 14.2±7.3 cm<sup>2</sup> (<em>P</em><0.001), extending from the RV outflow tract to the neighboring segments of the RV anterior wall. Postajmaline RV ejection fraction inversely correlated with postajmaline substrate extent (<em>r</em>=-0.830, <em>P</em><0.001). In patients with BrS and normal controls, cardiac magnetic resonance detected neither myocardial fibrosis nor RV outflow tract morphological abnormalities.</p> <p><strong>Conclusions: </strong>BrS is a dynamic RV electromechanical disease, where functional abnormalities correlate with the maximal extent of the substrate size.</p>
Dataset related to the article "Cardiac magneticresonanceforprophylactic implantable-cardioverter defibrillator therapy international study:prognosticvalueofcardiac magnetic resonance-derivedrightventricular parameters substudy"
<p>This record contains partial raw data related to the article “Cardiac magneticresonanceforprophylactic implantable-cardioverter defibrillator therapy international study:prognosticvalueofcardiac magnetic resonance-derivedrightventricular parameters substudy"</p> <p><strong>Aims: </strong>Right ventricular (RV) systolic dysfunction (RVSD) has been recognized as an important determinant of outcomes in heart failure (HF) patients. However, assessment of RV volumes is challenging as the geometric complexity of the RV prohibits quantitative assessment by traditional 2D-echocardiography. Cardiac magnetic resonance (CMR) is the gold standard for RV chamber quantification with its high spatial resolution, precise definition of anatomy, and excellent reproducibility. In this study, we sought to investigate the incremental prognostic value of CMR-derived RV volumetric parameters in a large cohort of HF patients with reduced ejection fraction (HFrEF).</p> <p><strong>Methods and Results: </strong>Study cohort comprised of patients enrolled in the CarDiac MagnEtic Resonance for Primary Prevention Implantable CardioVerter DefibrillAtor ThErapy registry who had HFrEF and had simultaneous baseline CMR and echocardiography<br> (n=2449). RVSD was defined as RV ejection fraction (RVEF) <45%. Kaplan–Meier curves and cox regression were used to investigate the association between RVSD and all-cause mortality (ACM). Mean age was 59.8±14.0 years, 42.0% were female, and mean left ventricular ejection fraction (LVEF) was 34.0±10.8. Median follow-up was 959 days (interquartile range: 560–1590). RVSD was present in 936 (38.2%) and was an independent predictor of ACM (adjusted hazard ratio=1.44; 95%CI[1.09–1.91]; P=0.01). On subgroup analyses,the prognostic value of RVSD was more pronounced in NYHA I/II than in NYHAIII/IV, in LVEF <35% than in LVEF ≥35%, and in patients with renal dysfunction when compared to those with normal renal function.</p> <p><strong>Conclusions: </strong>RV dysfunction is an independent predictor of all-cause mortality in a large cohort of patients with HFrEF, with the prognostic value of RV dysfunction being more pronounced in select subgroups; likely reflecting the importance of RV function in the early stages of HF progression.</p>
Quantitative Assessment of Late Gadolinium Enhancement and Edema at Cardiac Magnetic Resonance in Low-Risk Myocarditis Patients
<p>Monti CB, Secchi F, Alì M, Carbone FS, Bonomo L, Capra D, Mobini N, Di Leo G, Sardanelli F. Quantitative Assessment of Late Gadolinium Enhancement and Edema at Cardiac Magnetic Resonance in Low-Risk Myocarditis Patients. Tomography. 2022 Apr 1;8(2):974-984. doi: 10.3390/tomography8020078. PMID: 35448712; PMCID: PMC9028348.</p> <p>Abstract</p> <p>In this study, we aimed to quantify LGE and edema at short-tau inversion recovery sequences on cardiac magnetic resonance (CMR) in patients with myocarditis. We retrospectively evaluated CMR examinations performed during the acute phase and at follow-up. Forty-seven patients were eligible for retrospective LGE assessment, and, among them, twenty-five patients were eligible for edema evaluation. Both groups were paired with age- and sex-matched controls. The median left ventricle LGE was 6.4% (interquartile range 5.0-9.2%) at the acute phase, 4.4% (3.3-7.2%) at follow-up, and 4.3% (3.0-5.3%) in controls, the acute phase being higher than both follow-up and controls (<em>p &lt;</em> 0.001 for both), while follow-up and controls did not differ (<em>p =</em> 0.139). An optimal threshold of 5.0% was obtained for LGE with 87% sensitivity and 48% specificity; the positive likelihood ratio (LR) was 1.67, and the negative LR was 0.27. Edema was 12.8% (9.4-18.1%) at the acute phase, 7.3% (5.5-8.8%) at follow-up, and 6.7% (5.6-8.6%) in controls, the acute phase being higher than both follow-up and controls (both <em>p &lt;</em> 0.001), while follow-up and controls did not differ (<em>p =</em> 0.900). An optimal threshold of 9.5% was obtained for edema with a sensitivity of 76% and a specificity of 88%; the positive LR was 6.33, and the negative LR was 0.27. LGE and edema thresholds are useful in cases of suspected mild myocarditis.</p>
Quantitative Assessment of Late Gadolinium Enhancement and Edema at Cardiac Magnetic Resonance in Low-Risk Myocarditis Patients
<p>Monti CB, Secchi F, Alì M, Carbone FS, Bonomo L, Capra D, Mobini N, Di Leo G, Sardanelli F. Quantitative Assessment of Late Gadolinium Enhancement and Edema at Cardiac Magnetic Resonance in Low-Risk Myocarditis Patients. Tomography. 2022 Apr 1;8(2):974-984. doi: 10.3390/tomography8020078. PMID: 35448712; PMCID: PMC9028348.</p> <p>Abstract</p> <p>In this study, we aimed to quantify LGE and edema at short-tau inversion recovery sequences on cardiac magnetic resonance (CMR) in patients with myocarditis. We retrospectively evaluated CMR examinations performed during the acute phase and at follow-up. Forty-seven patients were eligible for retrospective LGE assessment, and, among them, twenty-five patients were eligible for edema evaluation. Both groups were paired with age- and sex-matched controls. The median left ventricle LGE was 6.4% (interquartile range 5.0-9.2%) at the acute phase, 4.4% (3.3-7.2%) at follow-up, and 4.3% (3.0-5.3%) in controls, the acute phase being higher than both follow-up and controls (<em>p &lt;</em> 0.001 for both), while follow-up and controls did not differ (<em>p =</em> 0.139). An optimal threshold of 5.0% was obtained for LGE with 87% sensitivity and 48% specificity; the positive likelihood ratio (LR) was 1.67, and the negative LR was 0.27. Edema was 12.8% (9.4-18.1%) at the acute phase, 7.3% (5.5-8.8%) at follow-up, and 6.7% (5.6-8.6%) in controls, the acute phase being higher than both follow-up and controls (both <em>p &lt;</em> 0.001), while follow-up and controls did not differ (<em>p =</em> 0.900). An optimal threshold of 9.5% was obtained for edema with a sensitivity of 76% and a specificity of 88%; the positive LR was 6.33, and the negative LR was 0.27. LGE and edema thresholds are useful in cases of suspected mild myocarditis.</p>
Dataset related to the article "Cardiac Magnetic Resonance for Prophylactic Implantable-Cardioverter Defibrillator Therapy in Ischemic Cardiomyopathy The DERIVATE–ICM International Registry"
<p>This record contains raw data related to the article “Cardiac Magnetic Resonance for Prophylactic Implantable-Cardioverter Defibrillator Therapy in Ischemic Cardiomyopathy The DERIVATE–ICM International Registry”</p> <p><strong>BACKGROUND</strong> Implantable cardioverter-defibrillator (ICD) therapy is the most effective prophylactic strategy against sudden cardiac death (SCD) in patients with ischemic cardiomyopathy (ICM) and left ventricle ejection fraction (LVEF) #35% as detected by transthoracic echocardiograpgy (TTE). This approach has been recently questioned because of the low rate of ICD interventions in patients who received implantation and the not-negligible percentage of patients who experienced SCD despite not fulfilling criteria for implantation.</p> <p><strong>OBJECTIVES</strong> The DERIVATE (CarDiac MagnEtic Resonance for Primary Prevention Implantable CardioVerter DebrillAtor ThErapy)-ICM registry (NCT03352648) is an international, multicenter, and multivendor study to assess the net reclassification improvement (NRI) for the indication of ICD implantation by the use of cardiac magnetic resonance (CMR) as compared to TTE in patients with ICM.</p> <p><strong>METHODS</strong> A total of 861 patients with ICM (mean age 65 [1] 11 years, 86% male) with chronic heart failure and TTE-LVEF <50% participated. Major adverse arrhythmic cardiac events (MAACE) were the primary endpoints. RESULTS During a median follow-up of 1,054 days, MAACE occurred in 88 (10.2%). Left ventricular end-diastolic volume index (HR: 1.007 [95% CI: 1.000-1.011]; P ¼ 0.05), CMR-LVEF (HR: 0.972 [95% CI: 0.945-0.999]; P ¼ 0.045) and late gadolinium enhancement (LGE) mass (HR: 1.010 [95% CI: 1.002-1.018]; P ¼ 0.015) were independent predictors of MAACE. A multiparametric CMR weighted predictive derived score identifies subjects at high risk for MAACE compared with TTE-LVEF cutoff of 35% with a NRI of 31.7% (P ¼ 0.007).</p> <p><strong>CONCLUSIONS</strong> The DERIVATE-ICM registry is a large multicenter registry showing the additional value of CMR to stratify the risk for MAACE in a large cohort of patients with ICM compared with standard of care.</p>
Data set from the article Petrini M, Alì M, Cannaò PM, Zambelli D, Cozzi A, Codari M, Malavazos AE, Secchi F, Sardanelli F. Epicardial adipose tissue volume in patients with coronary artery disease or non-ischaemic dilated cardiomyopathy: evaluation with cardiac magnetic resonance imaging. Clin Radiol. 2019 Jan;74(1):81.e1-81.e7. doi: 10.1016/j.crad.2018.09.006. Epub 2018 Oct 15. PMID: 30336943.
<p>Data set from the article Petrini M, Alì M, Cannaò PM, Zambelli D, Cozzi A, Codari M, Malavazos AE, Secchi F, Sardanelli F. Epicardial adipose tissue volume in patients with coronary artery disease or non-ischaemic dilated cardiomyopathy: evaluation with cardiac magnetic resonance imaging. Clin Radiol. 2019 Jan;74(1):81.e1-81.e7. doi: 10.1016/j.crad.2018.09.006. Epub 2018 Oct 15. PMID: 30336943.</p> <p> </p> <p>This is the abstract:</p> <p><strong>Aim: </strong> To compare the amount of epicardial adipose tissue (EAT) in patients with coronary artery disease (CAD) or non-ischaemic dilated cardiomyopathy (NIDCM) with that in patients with negative cardiac magnetic resonance imaging (CMR).</p> <p><strong>Materials and methods: </strong> One hundred and fifty patients (median age 57 years, interquartile range [IQR] 46-66 years) who underwent CMR were evaluated retrospectively: 50 with CAD, 50 with NIDCM, and 50 with negative CMR. For each patient, the EAT mass index (EATMI) to body surface area, end-diastolic volume index (EDVI), end-systolic volume index (ESVI), stroke volume (SV), ejection fraction (EF) for both ventricles, and left ventricle (LV) mass index were estimated. Intra and inter-reader reproducibility was tested in a random subset of 30 patients, 10 for each group. Mann-Whitney U test, Kruskal-Wallis test, Spearman's correlation, and Bland-Altman statistics were used.</p> <p><strong>Results: </strong> The EATMI in CAD patients (median 15.7 g/m<sup>2</sup>, IQR 8.3-25.7) or in NIDCM patients (15.9 g/m<sup>2</sup>, 11.5-18.1) was significantly higher than that in negative CMR patients (9.1 g/m<sup>2</sup>, 6-12; p<0.001 both). No significant difference was found between CAD and NIDCM patients (p=1.000). A correlation between EATMI and LV mass index was found in NIDCM patients (r=0.455, p=0.002). Intra- and inter-reader reproducibility were up to 80% and 72%, respectively.</p> <p><strong>Conclusion: </strong> Patients with NIDCM or CAD exhibited an increased EATMI in comparison to negative CMR patients. CMR can be used to estimate EAT with good reproducibility.</p>
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
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DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.