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539
datasets available to search
ShareScore release 0.7.1
Dataset results
539 results for “loss of function.”
Loss of Function Mutations in ETS2 Repressor Factor (ERF) Reveal a Balance Between Positive and Negative ETS Factors Controlling Prostate Oncogenesis [22PC RNA-seq]
GEO Series GSE83649. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
Only the loss-of-function but not the gain-of-function properties of mutant TP53 are critical for the sustained proliferation, survival and metastasis of a broad range of cancer cells
GEO Series GSE181016. Homo sapiens. 18 samples. Type: Expression profiling by high throughput sequencing.
Roles of PKLR in NAFLD using loss- and gain-of-function mouse models
GEO Series GSE151182. Mus musculus. 20 samples. Type: Expression profiling by high throughput sequencing.
Genome-wide CRISPR loss-of-function screen for α-amanitin
GEO Series GSE226447. Homo sapiens. 4 samples. Type: Other.
Effect of PRC2 loss of function on gene and TE expression in Cyanidioschyzon merolae
GEO Series GSE221632. Cyanidioschyzon merolae strain 10D. 6 samples. Type: Expression profiling by high throughput sequencing.
Rescuing DNMT1 Fails to Fully Reverse the Molecular and Functional Repercussions of Its Loss in Mouse Embryonic Stem Cells [mRNA-seq]
GEO Series GSE266928. Mus musculus. 48 samples. Type: Expression profiling by high throughput sequencing.
CRISPR GENome and Epigenome Engineering (CRISPRgenee) improves loss-of-function genetic screening approaches
GEO Series GSE238225. synthetic construct; Homo sapiens. 19 samples. Type: Other.
Exome-wide rare loss-of-function variant enrichment study in 21,347 Han Chinese individuals identifies four new susceptibility genes for psoriasis [healthy controls]
GEO Series GSE131670. Homo sapiens. 12398 samples. Type: Genome variation profiling by array; SNP genotyping by SNP array.
Acute loss of TET function results in aggressive myeloid cancer in mice [RNA-Seq]
GEO Series GSE72628. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.
CRISPR library knockout screening identified candidate genes whose loss of function confers lapatinib resistance in HER2-amplified GC cells.
GEO Series GSE148668. Homo sapiens. 12 samples. Type: Other.
Loss of homeostatic functions in microglia from a murine model of Friedreich’s ataxia
GEO Series GSE232826. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing.
Bacterial Adaptation Through Loss of Function
GEO Series GSE30345. Escherichia coli O157:H7 str. EDL933; Escherichia coli str. K-12 substr. MG1655; Escherichia coli O157:H7 str. Sakai; Escherichia coli CFT073. 16 samples. Type: Expression profiling by array.
The transcriptome of hand2 loss- and gain-of-function embryonic cardiomyocytes
GEO Series GSE241049. Danio rerio. 12 samples. Type: Expression profiling by high throughput sequencing.
PAX4 loss of function alters human endocrine cell development and influences diabetes risk [dateset 1]
GEO Series GSE202206. Homo sapiens. 68 samples. Type: Expression profiling by high throughput sequencing.
Loss or oncogenic mutation of DROSHA impairs kidney development and function, but is not sufficient for Wilms tumor formation
GEO Series GSE117665. Mus musculus. 9 samples. Type: Non-coding RNA profiling by high throughput sequencing.
Expression profiling of Dicer loss-of-function macrophages
GEO Series GSE106854. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.
Gene expression profiling of melanoma cell lines (carrying NF1 loss-of-function) treated with DMSO (vehicle), MTX-216, MTX-211, trametinib, the combination of MTX-216 and trametinib, or pictilisib
GEO Series GSE213588. Homo sapiens. 42 samples. Type: Expression profiling by high throughput sequencing.
Loss of neuronal Tet2 enhances hippocampal-dependent cognitive function
GEO Series GSE171295. Mus musculus. 37 samples. Type: Expression profiling by high throughput sequencing.
Ash1l loss-of-function results in structural birth defects and altered cortical development [scRNA-seq]
GEO Series GSE252688. Mus musculus. 7 samples. Type: Expression profiling by high throughput sequencing.
RB1 loss promotes a noncanonical activator function of LSD1 and sensitizes castration-resistant prostate cancer to LSD1 inhibition [RNA-seq]
GEO Series GSE176403. Homo sapiens. 30 samples. Type: Expression profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.