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2,002
datasets available to search
ShareScore release 0.9.0
Dataset results
2,002 results for “sarcoma”
Virus-like vesicles of Kaposi’s Sarcoma-Associated Herpesvirus activate lytic replication through triggering differentiation signaling
GEO Series GSE91386. Homo sapiens; Human gammaherpesvirus 8. 15 samples. Type: Expression profiling by high throughput sequencing; Non-coding RNA profiling by high throughput sequencing.
Low KLF11 Determines the CSC–like Identity in Sarcoma via restraining YAP transactivity [ChIP-seq]
GEO Series GSE133310. Homo sapiens. 11 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Gene expression in sarcoma cell lines
GEO Series GSE213936. Homo sapiens. 15 samples. Type: Expression profiling by high throughput sequencing.
The SS18-SSX oncoprotein hijacks KDM2B-PRC1.1 to drive synovial sarcoma
GEO Series GSE108929. Homo sapiens. 40 samples. Type: Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing.
Differential chromatin landscape in myxoid liposarcoma and Ewing sarcoma
GEO Series GSE235218. Homo sapiens. 6 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
DNA demethylating agents represent a therapeutic opportunity for synovial sarcoma
GEO Series GSE292622. Mus musculus. 9 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Methylation profile of ewing sarcoma cell lines
GEO Series GSE118872. Homo sapiens. 24 samples. Type: Methylation profiling by array.
Aberrant gene activation in synovial sarcoma relies on SSX specificity and increased PRC1.1 stability
GEO Series GSE233375. Homo sapiens. 12 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Epigenetic profiling of well differentiated and dedifferentiated liposarcoma identifies H3K9me3 and Kruppel-like factor 6 (KLF6) as determinants of aggressiveness in sarcoma (expression)
GEO Series GSE57750. Homo sapiens. 18 samples. Type: Expression profiling by array.
Insulin-Like Growth Factor Receptor 1 and Mammalian Target Of Rapamycin Blockade: Novel Mechanisms of Resistance and Synergistic Drug Combinations for Ewing Sarcoma
GEO Series GSE78124. Homo sapiens. 54 samples. Type: Protein profiling by protein array.
RNA-seq data of knowk-down of STAG2 or EWSR1-FLI1 in Ewing sarcoma cell lines (siCT, siEF1 & siSA2)
GEO Series GSE156653. Homo sapiens. 58 samples. Type: Expression profiling by high throughput sequencing.
RNA sequencing data from murine KP230 undifferentiated pleomorphic sarcoma cells treated with N-Benzylquinazolin-4-amine (NB4A)
GEO Series GSE198909. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
The chromatin landscape of primary synovial sarcoma organoids is linked to specific epigenetic mechanisms and dependencies.
GEO Series GSE148724. Homo sapiens; Mus musculus. 106 samples. Type: Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing.
Childhood Cancer Data Initiative (CCDI): Pediatric In Vivo Testing Program -Sarcoma, Kidney, and Liver Cancers
The goal was to complete whole exome sequencing (WES) and RNA sequencing (RNA-Seq) on patient derived xenograft samples. Cancer in children is rare with approximately 15,700 new cases diagnosed annually in children 21 years or younger in the U.S. Through use of multimodality therapy (surgery, radiation therapy, and aggressive chemotherapy), 70% of patients will be 'cured' of their disease, and 5-year Event-Free Survival (EFS) exceeds 80%. Consequently, the number of patients that can be enrolled in phase I/II clinical trials is small, and most patients will have been extensively treated, hence drug/radiation resistant. Thus, preclinical studies that accurately translate into effective clinical therapy are an essential component of pediatric drug development. Our group has contributed to studies in the Pediatric Preclinical Testing Program (PPTP) and Pediatric Preclinical Testing Consortium (PPTC) that have led to clinical studies through Children's Oncology Group (COG). Of importance, we have developed and characterized over 330 Patient Derived Xenografts (PDX), developed from tumors both at diagnosis and relapse, that can be used to facilitate pediatric drug development as directed by FDA under the Research to Accelerate Cures and Equity for Children Act (RACE for Children Act).
Genomic Sequencing of Ewing's Sarcoma
The Ewing sarcoma family of tumors is a group of malignant small round blue cell tumors that arise in bone or soft tissue. Ewing sarcoma (ES) is the second most common type of primary bone tumor to affect children and adolescents and accounts for 2.9% of all childhood cancers. This dataset reports whole-genome sequencing of primary Ewing's Sarcoma samples and matching germline samples.
Genomic Sequencing of Ewing Sarcoma
Pediatric Ewing sarcoma is a pediatric cancer that primarily arises from the bone. It is characterized by chimeric fusions of the EWS gene and an ETS family transcription factor. In this study, we performed massively parallel sequencing of a larger collection of Ewing sarcoma tumors to define the genomic landscape of this disease. We found that these tumors are among of the most genetically normal cancers currently characterized. There was also a marked absence of recurrent mutations in immediately targetable signaling transduction pathway genes. In this study we answer outstanding questions about ETS transcription factor expression, effects of treatment on mutational burden in Ewing sarcoma tumors, and describe patterns of tumor evolution. We also found that loss-of-function mutations in STAG2 were present in approximately 15% of Ewing sarcoma tumors and loss of STAG2 expression was associated with disease metastasis in this patient cohort.
The long non-coding RNA lnc277 mediates a repressive gene signature in Ewing's sarcoma and is required for oncogenesis
GEO Series GSE60891. Homo sapiens. 10 samples. Type: Expression profiling by high throughput sequencing.
ASPSCR1::TFE3 Drives Alveolar Soft Part Sarcoma by Inducing Targetable Transcriptional Programs
GEO Series GSE235739. Homo sapiens. 62 samples. Type: Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing.
AIDS-related Kaposi's sarcoma
GEO Series GSE514. Homo sapiens. 7 samples. Type: Expression profiling by SAGE.
The FLI portion of EWS/FLI contributes a transcriptional regulatory function that is distinct from its DNA-binding function in Ewing sarcoma [RNA-seq III]
GEO Series GSE173414. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.