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3,790
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ShareScore release 0.7.1
Dataset results
3,790 results for “anxiety”
Transcriptomes of BNST brain regions from mouse model of anxiety
GEO Series GSE266128. Mus musculus. 20 samples. Type: Expression profiling by high throughput sequencing.
Gain of bipolar disorder-related lncRNA AP1AR-DT in mice induces depressive and anxiety-like behaviors by reducing Negr1-mediated excitatory synaptic transmission [SK-N-SH RNA-seq]
GEO Series GSE272752. Homo sapiens. 4 samples. Type: Expression profiling by high throughput sequencing.
HM450 analysis pregnancy anxiety
GEO Series GSE104376. Homo sapiens. 45 samples. Type: Methylation profiling by genome tiling array.
Tet3 ablation in adult brain neurons increases anxiety-like behavior and regulates cognitive function in mice
GEO Series GSE140850. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.
Prenatal adversity configures the transcriptome of a subpopulation of ventral dentate granule cells for recruitment to drive innate anxiety
GEO Series GSE284463. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing.
Ppm1f is regulated by stress and associated with anxiety and depression [amygdala]
GEO Series GSE100084. Mus musculus. 16 samples. Type: Expression profiling by array.
Overexpressing NEGR1 gene in mice brain induces anxiety or depression-like phenotypes and synaptic dysfunction
GEO Series GSE292811. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Blast-related mild TBI alters anxiety-like behavior and transcriptional signatures in the rat amygdala
GEO Series GSE155393. Rattus norvegicus. 62 samples. Type: Expression profiling by high throughput sequencing.
Transcriptomes across seven brain regions from mouse model of anxiety
GEO Series GSE254448. Mus musculus. 10 samples. Type: Expression profiling by high throughput sequencing.
Genitourinary defects, anxiety and aggressive-like behavior and glucose metabolism disorders in Zmym2 mutant mice with inserted piggyBac transposon
GEO Series GSE305505. Mus musculus. 9 samples. Type: Expression profiling by high throughput sequencing.
Deficiency of hypothalamic taste receptor type 1 member 3 prevents western diet-induced anxiety in mice
GEO Series GSE216063. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.
Urolithin A abolishes high anxiety and rescues the associated mitochondrial transcriptomic signatures and synaptic function
GEO Series GSE297773. Rattus norvegicus. 3 samples. Type: Expression profiling by high throughput sequencing.
Prenatal adversity configures the transcriptome of a subpopulation of ventral dentate granule cells for recruitment to drive innate anxiety
GEO Series GSE284416. Mus musculus. 8 samples. Type: Methylation profiling by high throughput sequencing.
Histone methyltransferase SETDB1 selectively regulates cortical HTR3A interneuron development and anxiety-like behavior in mice
GEO Series GSE186806. Mus musculus. 17 samples. Type: Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing.
Maternal anxiety during pregnancy and newborn epigenome-wide DNA methylation
<p>Maternal anxiety during pregnancy is associated with adverse fetal, neonatal, and child outcomes, but biological mechanisms remain unclear. Altered fetal DNA methylation (DNAm) has been proposed as a potential underlying mechanism. In the current study, we performed a meta-analysis to examine the associations between maternal anxiety, measured prospectively during pregnancy, and genome-wide DNAm from umbilical cord blood. Sixteen non-overlapping cohorts from 12 independent longitudinal studies of the Pregnancy And Childhood Epigenetics Consortium participated, resulting in a combined dataset of 7 243 mother-child dyads. We examined prenatal anxiety in relation to genome-wide DNAm and differentially methylated regions. We observed no association between the general symptoms of anxiety during pregnancy or pregnancy-related anxiety, and DNAm at any of the CpG sites, after multiple-testing correction. Further, we identify no differentially methylated regions associated with maternal anxiety. At the cohort-level, of the 21 associations observed in individual cohorts, none replicated consistently in the other cohorts. In conclusion, contrary to some previous studies proposing cord blood DNAm as a promising potential mechanism explaining the link between maternal anxiety during pregnancy and adverse outcomes in offspring, we found no consistent evidence for any robust associations between maternal anxiety and DNAm in cord blood. Larger studies and analysis of DNAm in other tissues may be needed to establish subtle or subgroup-specific associations between maternal anxiety and the fetal epigenome.</p> <p>In this dataset, we present all probe-level summary statistics for one of the two secondary meta-analyses, as described in more detail in the publication (Sammallahti, Cortes Hidalgo, et al, Molecular Psychiatry, in press). We present here the associations between maternal anxiety during pregnancy (general rather than pregnancy-related anxiety; binary variable where 1=high and 0=low anxiety) and cord blood DNA methylation at birth (continuous beta values where 1=completely methylated and 0=completely unmethylated) of <strong>CpG sites that were only present in the Illumina EPIC array</strong> (not on the Illumina 450k array). We adjusted for child sex, maternal socioeconomic class, maternal age, ancestry, batch, and cell counts. The sample size, unadjusted p-value, the z estimate from the sample-size weighted meta-analysis, and the direction of effects across each cohorts are shown.</p> <p>Upload of this dataset was completed by The EWAS Catalog team. The data can be queried along with hundreds of other EWAS at ewascatalog.org. To upload your EWAS summary statistics and have a zenodo DOI generated for you go to ewascatalog.org/upload</p>
Maternal anxiety during pregnancy and newborn epigenome-wide DNA methylation
<p>Maternal anxiety during pregnancy is associated with adverse fetal, neonatal, and child outcomes, but biological mechanisms remain unclear. Altered fetal DNA methylation (DNAm) has been proposed as a potential underlying mechanism. In the current study, we performed a meta-analysis to examine the associations between maternal anxiety, measured prospectively during pregnancy, and genome-wide DNAm from umbilical cord blood. Sixteen non-overlapping cohorts from 12 independent longitudinal studies of the Pregnancy And Childhood Epigenetics Consortium participated, resulting in a combined dataset of 7 243 mother-child dyads. We examined prenatal anxiety in relation to genome-wide DNAm and differentially methylated regions. We observed no association between the general symptoms of anxiety during pregnancy or pregnancy-related anxiety, and DNAm at any of the CpG sites, after multiple-testing correction. Further, we identify no differentially methylated regions associated with maternal anxiety. At the cohort-level, of the 21 associations observed in individual cohorts, none replicated consistently in the other cohorts. In conclusion, contrary to some previous studies proposing cord blood DNAm as a promising potential mechanism explaining the link between maternal anxiety during pregnancy and adverse outcomes in offspring, we found no consistent evidence for any robust associations between maternal anxiety and DNAm in cord blood. Larger studies and analysis of DNAm in other tissues may be needed to establish subtle or subgroup-specific associations between maternal anxiety and the fetal epigenome.</p> <p>In this dataset, we present all probe-level summary statistics for the primary meta-analysis, as described in more detail in the publication (Sammallahti, Cortes Hidalgo, et al, Molecular Psychiatry, in press). We present the associations between maternal anxiety during pregnancy (general rather than pregnancy-related anxiety; binary variable where 1=high and 0=low anxiety) and cord blood DNA methylation at birth (continuous beta values where 1=completely methylated and 0=completely unmethylated) . We adjusted for child sex, maternal socioeconomic class, maternal age, ancestry, batch, and cell counts. The sample size, unadjusted p-value, the z estimate from the sample-size weighted meta-analysis, and the direction of effects across each cohorts are included.</p> <p>Results from the secondary meta-analyses concerning pregnancy-related anxiety (<a href="https://doi.org/10.5281/zenodo.4147845">https://doi.org/10.5281/zenodo.4147845</a>) and CpG sites that are only available on the Illumina EPIC array (<a href="https://doi.org/10.5281/zenodo.4147831">https://doi.org/10.5281/zenodo.4147831</a>) are presented separately</p> <p>Upload of this dataset was completed by The EWAS Catalog team. The data can be queried along with hundreds of other EWAS at ewascatalog.org. To upload your EWAS summary statistics and have a zenodo DOI generated for you go to ewascatalog.org/upload</p>
Maternal anxiety during pregnancy and newborn epigenome-wide DNA methylation
<p>Maternal anxiety during pregnancy is associated with adverse fetal, neonatal, and child outcomes, but biological mechanisms remain unclear. Altered fetal DNA methylation (DNAm) has been proposed as a potential underlying mechanism. In the current study, we performed a meta-analysis to examine the associations between maternal anxiety, measured prospectively during pregnancy, and genome-wide DNAm from umbilical cord blood. Sixteen non-overlapping cohorts from 12 independent longitudinal studies of the Pregnancy And Childhood Epigenetics Consortium participated, resulting in a combined dataset of 7 243 mother-child dyads. We examined prenatal anxiety in relation to genome-wide DNAm and differentially methylated regions. We observed no association between the general symptoms of anxiety during pregnancy or pregnancy-related anxiety, and DNAm at any of the CpG sites, after multiple-testing correction. Further, we identify no differentially methylated regions associated with maternal anxiety. At the cohort-level, of the 21 associations observed in individual cohorts, none replicated consistently in the other cohorts. In conclusion, contrary to some previous studies proposing cord blood DNAm as a promising potential mechanism explaining the link between maternal anxiety during pregnancy and adverse outcomes in offspring, we found no consistent evidence for any robust associations between maternal anxiety and DNAm in cord blood. Larger studies and analysis of DNAm in other tissues may be needed to establish subtle or subgroup-specific associations between maternal anxiety and the fetal epigenome.</p> <p>In this dataset, we present all probe-level summary statistics for one of the two secondary meta-analyses, as described in more detail in the publication (Sammallahti, Cortes Hidalgo, et al, Molecular Psychiatry, in press). We present the associations between maternal <strong>pregnancy-related anxiety</strong> during pregnancy (binary variable where 1=high and 0=low anxiety) and cord blood DNA methylation at birth (continuous beta values where 1=completely methylated and 0=completely unmethylated). We adjusted for child sex, maternal socioeconomic class, maternal age, ancestry, batch, and cell counts. The sample size, unadjusted p-value, the z estimate from the sample-size weighted meta-analysis, and the direction of effects across each cohorts are included.</p> <p>Upload of this dataset was completed by The EWAS Catalog team. The data can be queried along with hundreds of other EWAS at ewascatalog.org. To upload your EWAS summary statistics and have a zenodo DOI generated for you go to ewascatalog.org/upload</p>
Parkinson's Anxiety Network (anxiety-network-pd)
<p>An <em>a priori</em> anxiety network, based on previously reported results in structural and microstructural Parkinson’s disease anxiety literature.</p> <p>This network will be used in a region of interest analysis in a neuroimaging study characterising the microstructural basis of anxiety in early Parkinson's disease. It will be used alongside a High Density Anxiety Network <strong>(10.5281/zenodo.17158446).</strong></p> <p>This network was updated in September 2025 and replaced a previous version originally published in November 2024. Following advice from an advisory thesis committee, a systematic review of PD anxiety neuroannatomical literature was conducted to inform the network, replacing a previous narrative review. This resulted in small changes to the annatomical nodes of the network. The update includes the addition of the left inferior frontal gyrus (opercular and triangular part), bilateral medial orbital gyrus, left anteroventral nucleus of the thalamus, bilateral substantia nigra pars compacta and reticulata and ventral tegmental area. The left inferior frontal gyrus pars orbitalis was removed. All other regions remain the same. </p>
The role of conspiracy mentality, reactance, and anxiety in gain- vs. loss-framed promotion of COVID-19 protective measures: Is vaccination different?
<p>Data set and materials for <strong>The role of conspiracy mentality, reactance, and anxiety in gain- vs. loss-framed promotion of COVID-19 protective measures: Is vaccination different?</strong></p>
Hospital Anxiety and Depression Scale (HADS)
<p>Data set</p>
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.