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178
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ShareScore release 0.9.0
Dataset results
178 results for “Environmental Exposure*”
Survey of maize differential expression upon environmental exposure to the tar spot pathogen Phyllahcora maydis
GEO Series GSE296174. Zea mays; Phyllachora maydis. 12 samples. Type: Expression profiling by high throughput sequencing.
Lasting effects of early exposure to temperature on the gonadal transcriptome at the time of sex differentiation in the European sea bass, a fish with mixed genetic and environmental sex determination
GEO Series GSE52307. Dicentrarchus labrax. 10 samples. Type: Expression profiling by array.
HEPATIC GENE EXPRESSION PATTERNS IN JUVENILE TURBOTS (Scophthalmus maximus) AFTER EXPOSURE TO NO2 FUEL OIL (PRAGMA, a pragmatic and integrated approach for the evaluation of environmental impact of oi
GEO Series GSE43361. Scophthalmus maximus. 11 samples. Type: Expression profiling by array.
Chronic exposure of PFOS at environmental-relevant concentration promotes TNBC aggressive phenotypes
GEO Series GSE306911. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Impact of Exposure to an Environmentally Relevant Mixture of Organophosphate Esters on the Adrenal Glands of Sprague Dawley Rats
GEO Series GSE275797. Rattus norvegicus. 40 samples. Type: Expression profiling by high throughput sequencing.
HEPATIC GENE EXPRESSION PATTERNS IN JUVENILE TURBOTS (Scophthalmus maximus) AFTER EXPOSURE TO STYRENE (PRAGMA, a pragmatic and integrated approach for the evaluation of environmental impact of oil an
GEO Series GSE43359. Scophthalmus maximus. 25 samples. Type: Expression profiling by array.
Exposure of Children With Asthma to Household Environmental Tobacco Smoke
ClinicalTrials.gov study NCT00035685. IPD Sharing: Not stated. Countries: 0. Publications: 0.
Impact of exposure to environmentally-relevant concentrations of ionic silver and nanosilver on thyroid hormone-dependent postembryonic development of the North American bullfrog (Rana catesbeiana)
GEO Series GSE56523. Lithobates pipiens; Xenopus laevis; Aquarana catesbeiana. 72 samples. Type: Expression profiling by array.
Comparison of zebrafish toxicity among different developmental windows of exposure to three environmentally relevant PFAS compounds
GEO Series GSE242402. Danio rerio. 1006 samples. Type: Expression profiling by high throughput sequencing.
Differentiating Mouse Colon and Rectum: Transcriptional Differences and Environmental Exposure
GEO Series GSE38753. Mus musculus. 39 samples. Type: Expression profiling by array.
Acute and Chronic Environmental Tobacco Smoke Condensate Exposure to Primary Human Bronchial Epithelial Cells
GEO Series GSE4234. Homo sapiens. 24 samples. Type: Expression profiling by array.
Blood and Nasal Epigenetics Correlate to Allergic Rhinitis Symptom Development in the Environmental Exposure Unit
GEO Series GSE100386. Homo sapiens. 46 samples. Type: Methylation profiling by genome tiling array.
Environmental monobutyl phthalate exposure promotes liver cancer via reprogramming cholesterol metabolism and activation of the IRE1α-XBP1s pathway
GEO Series GSE248562. Homo sapiens. 25 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
AV8 gene therapy and environmental exposure precipitate cholestatic liver disease in a mouse model of X-linked myotubular myopathy
GEO Series GSE264209. Mus musculus. 26 samples. Type: Expression profiling by high throughput sequencing.
Prenatal exposure to environmental air pollution and psychosocial stress jointly contribute to the epigenetic regulation of the serotonin transporter gene in newborns
<p>This database includes the raw data linked with the paper “Prenatal exposure to environmental air pollution and psychosocial stress jointly contribute to the epigenetic regulation of the serotonin transporter gene in newborns” accepted for publication on Molecular Psychiatry. This study is part of the longitudinal and multi-centric “Measuring the outcomes of maternal COVID-19-related prenatal exposure (MOM-COPE)” study. Here, we report on the interactive influence of variations in antenatal exposures to maternal pandemic-related stress (PRS) and PM2.5 on SLC6A4 DNAm levels in newborns.</p> <p>Procedures</p> <p>Mother–infant dyads (N=307) were enrolled at delivery during the COVID-19 pandemic. Infants’ methylation status was assessed in 13 CpG sites within the SLC6A4 gene’s region (chr17:28562750–28562958) in buccal cells at birth and women retrospectively report on PRS. PM2.5 exposure throughout the entire gestation and at each gestational trimester was estimated using a spatiotemporal model based on residential address.</p> <p> </p> <p>Among several potentially confounding socio-demographic and health-related factors, infant’s sex was significantly associated with infants’ SLC6A4 DNAm levels, thus hierarchical regression models were adjusted for infant’s sex.</p> <p>Mother–infant dyads (N = 276) were recruited at delivery. Maternal trait anxiety, as a marker of antenatal chronic stress exposure, was assessed soon after delivery using the Stait-Trait Anxiety Inventory (STAI-Y). Infants’ BDNF DNAm at birth was assessed in 11 CpG sites in buccal cells whereas infants’ NE was assessed at 3 (N = 225) and 6 months (N = 189) using the Infant Behavior Questionnaire-Revised (IBQ-R).</p> <p>Analytical plan</p> <p>Principal component analysis (PCA) was used to reduce the number of CpG sites into a smaller set of factors.</p> <p>A four-factor solution, where the targeted CpG sites were aggregated in 4 main factors, showed the best fit to the data (Table 2). Principal Component 1 (PC1; composed of 6 CpG sites) and Principal Component 2 (PC2; composed of 3 CpG sites) accounted, respectively, for 31.6% and 12.8% of the total variance in SLC6A4 DNAm and were used in further analyses. Pearson correlations and independent samples t-tests were employed to explore the potential effect of sociodemographic and health-related variables on infant methylation levels. All variables found to be significantly associated with the outcomes examined were included as covariates in subsequent analyses. Separate hierarchical regression analyses were performed to evaluate the independent and interactive effects of maternal PRS and exposure to air pollution on infant methylation levels.</p> <p>Findings in brief</p> <p>Higher levels of SLC6A4 DNAm at 6 CpG sites were found in newborns born to mothers reporting higher levels of antenatal PRS and greater PM2.5 exposure across gestation, while adjusting for infant’s sex. These effects were especially evident when exposure to elevated PM2.5 occurred during the second trimester of pregnancy.</p>
Assessing Environmental Exposure to Viruses in Wastewater Treatment Plant and Swine Farm Scenarios with Next-generation Sequencing and Occupational Risk Approaches
<p>Target enrichment sequencing of aerosol and surface samples collected from wastewater treatment plant (WWTP) and swine farm scenarios. </p>
Environmental Exposures, Characteristics, and Treatment Outcomes of Hypersensitivity Pneumonitis at a Rural Appalachian Academic Medical Center: A Cross-sectional Study
<p>Data set for our research project titled above.</p>
Study of Childhood Leukemia and Environmental Pesticide and Other Chemical Exposures in California
Childhood leukemia is the most common type of childhood cancer and its etiology is largely unknown. Investigators in DCEG are collaborating with investigators at University of California at Berkeley on a population-based case-control study of childhood leukemia in the San Francisco Bay area and the agricultural Central Valley (35 counties). A substantial proportion of the population in this area is employed in agriculture or lives in close proximity to agricultural fields, making this an ideal study population to evaluate agricultural pesticide exposures and risk of childhood leukemia. Furthermore, a large proportion of the study population is Hispanic. No previous large-scale childhood leukemia studies have targeted Hispanics or agricultural populations. A major aim of the collaboration is to improve the exposure assessment of agricultural and home and garden pesticides by measuring pesticides in house dust samples.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.