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1,154 results for “Pooling”
Azure Swimming Pool Pripyat
Restoration of the legendary pool in Pripyat "Azure".In this model, some details may differ from reality.This is my first work on the creation of the building.Render: Source: Objaverse 1.0 / Sketchfab
Patterns and drivers of organic matter decomposition in peatland open-water pools
<p>The five .csv files from this entrance comprise data used in Arsenault et al. "Patterns and drivers of organic matter decomposition in peatland open-water pools". This article was published on August 2nd 2024 in Biogeosciences (https://doi.org/10.5194/bg-21-3491-2024).</p> <p>First three files contain data from the three phases of the research: the study spatiotemporal changes in fresh litter chemistry and decomposition rates using litterbags (file 'Arsenault_2024_LB'), the study of spatial variations in peatland pool sediment chemistry and decomposition (file 'Arsenault_2024_inc'), and the study of spatiotemporal change of pool water chemistry (file 'Arsenault_2024_water-chemistry').</p> <p>File 'Arsenault_2024_LB_raw' contains raw data from the litterbag experiment from which we derived the decomposition rate constant 'k' shown in the 'Arsenault_2024_LB' file. File 'Arsenault_2024_inc_raw' contains CH4 and CO2 concentrations and production rates from the incubation experiments.</p> <p>Variable units are shown in column headers.</p>
Profiling of linear B-cell epitopes against human coronaviruses in pooled sera sampled early in the COVID-19 pandemic
<p>Background: Antibodies play a key role in the immune defence against infectious pathogens. Understanding the underlying process of B cell recognition is not only of fundamental interest; it supports important applications within diagnostics and therapeutics. Whereas the nature of conformational B cell epitope recognition is inherently complicated, linear B cell epitopes offer a straightforward approach that potentially can be reduced to one of peptide recognition.</p> <p>Methods: Using an overlapping peptide approach representing the entire proteomes of the seven main coronaviruses known to infect humans, we analysed sera pooled from eight PCR-confirmed COVID-19 convalescents and eight pre-pandemic controls. Using a high-density peptide microarray platform, 13-mer peptides overlapping by 11 amino acids were in situ synthesised and incubated with the pooled primary serum samples, followed by development with secondary fluorochrome-labelled anti-IgG and -IgA antibodies. Interactions were detected by fluorescence detection. Strong Ig interactions encompassing consecutive peptides were considered to represent "high-fidelity regions" (HFRs). These were mapped to the coronavirus proteomes using a 60% homology threshold for clustering.</p> <p>Results: We identified 333 human coronavirus derived HFRs. Among these, 98 (29%) mapped to SARS-CoV-2, 144 (44%) mapped to one or more of the four circulating common cold coronaviruses (CCC), and 54 (16%) cross-mapped to both SARS-CoV-2 and CCCs. The remaining 37 (11%) mapped to either SARS-CoV or MERS-CoV. Notably, the COVID-19 serum was skewed towards recognising SARS-CoV-2-mapped HFRs, whereas the pre-pandemic was skewed towards recognising CCC-mapped HFRs. In terms of absolute numbers of linear B cell epitopes, the primary targets are the ORF1ab protein (60%), the spike protein (21%), and the nucleoprotein (15%) in that order; however, in terms of epitope density, the order would be reversed.</p> <p>Conclusion: We identified linear B cell epitopes across coronaviruses, highlighting pan-, alpha-, beta-, or SARS-CoV-2-corona-specific B cell recognition patterns. These findings could be pivotal in deciphering past and current exposures to epidemic and endemic coronavirus. Moreover, our results suggest that pre-pandemic anti-CCC antibodies may cross-react against SARS-CoV-2, which could explain the highly variable outcome of COVID-19. Finally, the methodology used here offers a rapid and comprehensive approach to high-resolution linear B-cell epitope mapping, which could be vital for future studies of emerging infectious diseases.</p>
Enhancing comparative T-cell receptor repertoire analysis in small biological samples through pooling homologous cell samples from multiple mice
<p>All data files used to generate the figures in the paper are shared in this project.</p> <p>Scripts are available on <a href="https://github.com/i3-unit/CRM_24" target="_blank" rel="noopener">GitHub</a>.</p>
Data and code from: Similar trait-based successional assembly in native and introduced plants despite species pool differences
<p>What drives the composition of invaded communities and the local abundance of introduced species are key questions in ecology. Community-assembly theory provides a useful framework for addressing these questions. Specifically, the environmental filtering model of community assembly predicts that a species' presence and abundance in a community depends on the interaction between its functional traits and the local environmental filters. However, for introduced species, larger-scale dispersal and introduction-related filters may restrict their regional trait pool. Here we tested this framework using long-term data from 50+ years of old-field vegetation succession. We asked whether native and introduced plant assemblages followed the same trait-based assembly rules. We also asked whether local functional dissimilarities between the two can be explained by regional species pool differences, a possibility that has rarely been addressed. We found strong similarities in the assembly processes of native and introduced plants. Average height and seed mass of both groups increased over time, consistent with previous studies of old-field succession. Moreover, the two showed similar trait-abundance relationships. While there were also some differences, particularly in their trait-incidence relationships, these differences appeared to be minor.Further, we identified species pool constraints on introduced species, and found that the exotic species pool was biased towards early successional traits. Lastly, we found that highly invasive exotic species were also likely to deviate from the expected trait-abundance relationship, suggesting a link between the two. These results suggest that introduced species generally follow the same assembly rules as native species. They also indicate that species pool differences can result in local functional composition differences, even when the two groups follow the same assembly rules. Moreover, there may be a link between species invasiveness and deviation from assembly rules, which, if further confirmed, provides a potential method of identifying strong invaders.</p>
Size-Dependent Dynamics of the Internal Carbon Pool Drive Isotopic Vital Effects in Calcifying Phytoplankton
<p>Isotopic offsets in biogenic calcite from equilibrium values can provide unique insights into the physiology and mechanisms of carbon regulation in calcifying phytoplankton. This study examines the impact of varying CO2 (controlled via pH) on five coccolithophore species chosen for varied cell sizes, physiology, and calcification. The study investigates isotopic offsets in coccolith calcite and organic matter, in relation to carbon demand and supply (<i>µ</i>/CO2). Species-specific CO2/pH optima for growth (<i>µ</i>opt) were derived from variations in growth rates with varying CO2 concentrations. Growth rates for all species declined with rising CO2 (decreasing pH) due to H+-driven inhibition. <i>C. braarudii </i>and<i> C. leptoporus</i> exhibited high <i>µ</i>opt values (suggesting high carbon-demand) and limited growth under low CO2 (high pH) suggesting carbon limitation. Under low CO2 supply, when growth rates were CO2-limited, both species exhibited coincident isotopic depletion in calcite and organic matter as a consequence of CO2 diffusion into the cell that experienced no equilibration as a result of a highly depleted internal carbon pool. In these two species, isotopic values in calcite remained unaffected by growth rates and CO2 concentration (<i>µ</i>/CO2) when CO2 was sufficient for optimal growth. <i>G. huxleyi </i>and<i> G. oceanica </i>displayed optima for growth (<i>µ</i>opt) at low CO2 concentrations and showed no growth limitation under low CO2 (indicating low carbon-demand). Both species experienced depleted (negative) vital effects caused by an excess of CO2 diffusion into the small internal carbon pool of the cell when diffusive carbon supply outpaced low demand (low <i>µ</i>/CO2). Enriched (positive) vital effects were observed under low carbon supply and high demand, likely due to diffusive loss of CO2 from the cell's intracellular carbon pool due to a lower intracellular pH. <i>C. carterae</i> exhibited an intermediate <i>µ</i>opt and isotopically equilibrated intracellular carbon pool such that δ13C values in calcite and organic matter suggested a shared carbon pool. This study illustrates that pH-CO2 driven vital effects and fractionation into organic matter indicate the residence time for carbon in the intracellular carbon pool, and the size of this pool is proportional to cell size. <i>C. leptoporus </i>and<i> C. carterae</i> can elevate intracellular pH to minimise CO2 leakage, whereas vital effects in <i>G. huxleyi</i> and <i>G. oceanica </i>are caused by diffusive CO2 due to the small size of their internal carbon pool.</p>
Decrease in MJO predictability following Indo–Pacific Warm Pool Expansion
<p>Data:</p> <p>CTRL.clim.SST.nc: climatology SST for control simulation</p> <p>CTRL.clim.TMQ.nc: climatology TMQ for control simulation</p> <p>CTRL.tot.OLR.nc: 10yr daily OLR for control simulation</p> <p>CTRL.tot.U850.nc: 10yr daily U850for control simulation</p> <p>WPE.clim.SST.nc: climatology SST for WPEsimulation</p> <p>WPE.clim.TMQ.nc: climatology TMQ for WPEsimulation</p> <p>WPE.tot.OLR.nc: 10yr daily OLR for WPEsimulation</p> <p>WPE.tot.U850.nc: 10yr daily U850for WPEsimulation</p> <p>Figure:</p> <p>All figure generation files</p> <p>Program: </p> <p>Figure3.LREG.f90: lregression program</p> <p> </p> <p> </p>
Resolution, validation and divergence of heterozygous haplotypes from pooled long read sequencing of the diamondback moth (Lepidoptera: Plutellidae)
<p>This data sets includes the full set of intermediate genome assemblies produced during our analyses. We make these available for researchers who may be interested in the variation between assembly results and variation within the study organism (<em>Plutella xylostella</em>) prior to removal during subsequent genome processing.</p>
Dataset of "Hybrid modeling on 3D hydraulic features of a step-pool unit"
<p>In this repository you can find the data for the submission "Hybrid modeling on 3D hydraulic features of a step-pool unit" by Zhang et al. to Earth Surface Dynamics.</p> <p>The topographic models of the step-pool unit made of natural stones after FAVORization in FLOW3D for the six flow rates are kept in .stl files which were named after the flow rates (L/s). The mesh size for the step-pool feature is 2.5 mm for X, Y and Z directions. The locations, water level and flow velocity for the inlet boundary in all the numerical models are presented in the excel file. </p>
Videographic Data for Pore Formation and Melt Pool Analysis of Laser Welded Al-Cu Joints using Synchrotron Radiation
<p>The published data include video recordings of synchrotron radiation during a laser beam welding process in aluminium-copper joints. The recordings show the phase boundaries of the materials and are suitable for an analysis with regard to material mixing and pore formation. The experiments were conducted with the high energy beamline P07 (EH4) of Petra 3 at Deutsches Elektronen Synchrotron DESY in Hamburg, Germany.</p> <p>General parameters:</p> <p>Photon energy of synchrotron beam: 37,7 keV<br> Scintillator material: CdWO4<br> Frame rate: 1000 Hz</p> <p>Specific parameters used for videos:</p> <p>HV185: Cu-ETP (top) to Al99.5 (bottom); wavelengths of laser beam source: 1030 nm; laser beam diameter: 117 µm; laser power: 1000 W; feed rate: 50 mm/s<br> HV186: Cu-ETP (top) to Al99.5 (bottom); wavelengths of laser beam source: 1030 nm; laser beam diameter: 117 µm; laser power: 1500 W; feed rate: 100 mm/s<br> HV192: Al99.5 (top) to CuSn6 (bottom); wavelengths of laser beam source: 1070 nm; laser beam diameter: 34 µm; laser power: 750 W; feed rate: 50 mm/s<br> HV196: Cu-ETP (top) to Al99.5 (bottom); wavelengths of laser beam source: 1070 nm; laser beam diameter: 34 µm; laser power: 750 W; feed rate: 50 mm/s</p>
Population genetics and biogeography of the lungwort lichen in North America support distinct Eastern and Western gene pools
<p>Populations of species with large spatial distributions are shaped by complex forces that differ throughout their ranges. To maintain the genetic diversity of species, genepool-based subsets of widespread species must be considered in conservation assessments. In this study, the population genetics of the lichenized fungus Lobaria pulmonaria and its algal partner, Symbiochloris reticulata , were investigated to determine population structure, genetic diversity, and degree of congruency in eastern and western North America. Data loggers measuring temperature and humidity were deployed at selected populations in eastern North America to test for climatic adaptation. To better understand the role Pleistocene glaciations played in shaping population patterns, a North American, range-wide species distribution model was constructed and hindcast to 22,000 years before present and at 500-year time slices from then to the present. The presence of two gene pools with minimal admixture was supported, one in the Pacific Northwest and one in eastern North America. Western populations were significantly more genetically diverse than eastern populations. There was no evidence for climatic adaptation among eastern populations, though there was evidence for range-wide adaptation to evapotranspiration rates. Hindcast distribution models suggest that observed genetic diversity may be due to a drastic Pleistocene range restriction in eastern North America, whereas a substantial coastal refugial area is inferred in the west. Taken together the results show different, complex population histories of L. pulmonaria in eastern and western North America, and suggest that conservation planning for each gene pool should be considered separately.</p>
Data and processing scripts for PRISM barcode sequencing data used in "Massively parallel pooled screening reveals genomic determinants of nanoparticle-cell interactions"
<p>Sequencing data for the PRISM barcodes generated after nano-particle treatment is presented in this repository alongside the code to process the sequencing counts to generate the binning probabilities and weighted scores. <br> <br> For the details please see the original publication or the bioarxiv preprint: https://doi.org/10.1101/2021.04.05.438521<br> <br> The raw data is provided in PILOT_DATA_COUNTS.csv and EXPERIMENT_DATA_COUNTS.csv files, for the pilot and the actual experiment. <br> <br> For each of these files an R script is provided to process them, along with the output of the scripts (PILOT_DATA_PROBABILITIES.csv and EXPERIMENT_DATA_PROBABILITIES.csv)</p>
Structural variants in the barley gene pool: precision and sensitivity to detect them using short-read sequencing and their association with gene expression and phenotypic variation
<p>SNV of 23 parental barley inbreds of the double round robin population (DRR) (<a href="https://doi.org/10.1111/pbi.13746">https://doi.org/10.1111/pbi.13746</a>) used in the publication "Structural variants in the barley gene pool: precision and sensitivity to detect them using short-read sequencing and their association with gene expression and phenotypic variation". SV, INDELs, and additional data are available via figshare (https://doi.org/10.6084/m9.figshare.16802473).</p>
Evidence of an additional center of apple domestication in Iran, with contributions from the Caucasian crab apple <i>Malus orientalis</I> Uglitzk. to the cultivated apple gene pool
<p>Abstract</p> <p>Divergence processes in crop-wild fruit tree complexes in pivotal regions for plant domestication such as the Caucasus and Iran remain little studied. We investigated anthropogenic and natural divergence processes in apples in these regionsusing 26 microsatellite markers amplified in 550 wild and cultivated samples. We found two genetically distinct cultivated populations in Iran that are differentiated from <em>Malus domestica</em>, the standard cultivated apple worldwide. Coalescent-based inferences showed that these two cultivated populations originated from specific domestication events of <em>Malus orientalis</em> in Iran. We found evidence of substantial wild-crop and crop-crop gene flow in the Caucasus and Iran, as has been described in apple in Europe. In addition, we identified seven genetically differentiated populations of wild apple (<em>M. orientalis</em>), not introgressed by the cultivated apple. Niche modeling combined with genetic diversity estimates indicated that these wild populations likely resulted from range changes during past glaciations. This study identifies Iran as a key region in the domestication of apple and <em>M. orientalis</em> as an additional contributor to the cultivated apple gene pool. Domestication of the apple tree therefore involved multiple origins of domestication in different geographic locations and substantial crop-wild hybridization, as found in other fruit trees. This study also highlights the impact of climate change on the natural divergence of a wild fruit tree and provides a starting point for apple conservation and breeding programs in the Caucasus and Iran.</p> <p>Methods</p> <p>Microsatellite genotyping data for <em>M. orientalis</em>, <em>M. sieversii</em> from Kazakhstan, <em>M. domestica</em> and <em>M. baccata</em> were from previously published studies, including: 207 <em>M. orientalis</em> individuals from Turkey, Armenia and Russia (23 sites, Tables S1 and S2, (Cornille et al., 2013; Cornille et al., 2012)), four apple cultivars from Armenia, 40 “pure” European cultivated <em>M. domestica</em> individuals (<em>i.e.</em>, not introgressed by <em>M. sylvestris</em>) (Tables S1 and S2, (Cornille et al., 2013, 2012)), 20 <em>M. sieversii</em> individuals from Kazakhstan (Cornille et al., 2013) and 22 <em>M. baccata</em> individuals from Russia (Cornille et al., 2012). We collected 257 new samples in 2017 in Iran and in 2018 in Kyrgyzstan (<em>M. sieversii</em>) for this study: 167 <em>M. orientalis</em> individuals from the Hyrcanian Forests and the Zagros region in Iran (Table S1), 48 local Iranian apple cultivars from the <em>Seed and Plant Improvement Institute</em> (Karaj, Iran) (Table S1) and 42 <em>M. sieversii</em> individuals from Kyrgyzstan. Note that for 18 of the 48 local Iranian samples, fruit size was measured (Table S1). Collections meet the requirements of the recently enacted Nagoya protocol on access to genetic resources and the fair and equitable sharing of benefits. Thus, a total of 550 individuals were analyzed, comprising 374 <em>M. orientalis</em>, 48 Iranian and four Armenian apple cultivars, 40 European apple cultivars belonging to <em>M. domestica, </em>62<em> M. sieversii </em>(from Kyrgyzstan and Kazakhstan) and 22<em> M. baccata</em> individuals (details are provided in Table S1).</p> <p>DNA from the new samples (<em>N </em>= 257) was extracted from dried leaves with the NucleoSpin plant II DNA extraction kit (Macherey & Nagel, Düren, Germanyâ) following the manufacturer’s instructions. Multiplex microsatellite PCR amplifications were performed with a multiplex PCR kit (Qiagen Inc.â) for 26 microsatellite markers as previously described (Cornille et al., 2012; Patocchi, Frei, Frey, & Kellerhals, 2009). Note that on each DNA plate, we included three controls, <em>i.e.,</em> one sample of <em>M. orientalis, </em>one of <em>M. sieversii</em> and one of <em>M. domestica</em> for which data were already available (Cornille et al., 2013). Genotypes of the controls were compared with the 2013 dataset. We retained only multilocus genotypes for which < 20 % of the data was missing. The suitability of these markers for population genetics analyses has been demonstrated in previous studies (Cornille et al., 2013; Cornille, Gladieux, & Giraud, 2013; Cornille et al., 2012). </p> <p>Software used</p> <p>-STRUCTURE <a href="https://web.stanford.edu/group/pritchardlab/structure.html">https://web.stanford.edu/group/pritchardlab/structure.html</a></p> <p>-ABCtoolbox: <a href="http://cmpg.unibe.ch/software/ABCtoolbox/">http://cmpg.unibe.ch/software/ABCtoolbox/</a></p> <p>-fastsimcoal2 <a href="http://cmpg.unibe.ch/software/fastsimcoal27/">http://cmpg.unibe.ch/software/fastsimcoal27/</a></p> <p>-Genepop: <a href="https://genepop.curtin.edu.au/">https://genepop.curtin.edu.au</a></p> <p>-R software</p>
Data for "Mineral soils are an important intermediate storage pool of black carbon in boreal forests"
<p>This data is used in the publication "Mineral soils are an important intermediate storage pool of black carbon in boreal forests".</p> <p>The column plot_id uniquely represents each sample plot in the study and matches the columns of the same name in the complementary dataset "<a href="https://doi.org/10.5281/zenodo.5078669">Dataset for 'Climatic Variation Drives Loss and Restructuring of Carbon and Nitrogen in Boreal Forest Wildfire'</a>". Odd numbers are burnt plots, while the burnt plot_id plus 1 is its paired control.</p> <p>Columns are labeled with the name of sampled soil layer and entries are their associated BC:W values. BC:W is unitless (formed by dividing grams black carbon by grams sample weight). Empty spots mean there was no material at the plot to collect.</p>
Automated and manual pooled sample testing with panther fusion and aptima SARS-CoV-2 assays
<p>Combining diagnostic specimens into pools has been considered as a strategy to augment throughput, decrease turnaround time, and leverage resources. This study utilized a multi-parametric approach to assess optimum pool size, impact of automation, and effect of nucleic acid amplification chemistries on the detection of SARS-CoV-2 RNA in pooled samples for surveillance testing on the Hologic Panther Fusion® System. Dorfman pooled testing was conducted with previously tested SARS-CoV-2 nasopharyngeal samples using Hologic's Aptima® and Panther Fusion® SARS-CoV-2 Emergency Use Authorization assays. A manual workflow was used to generate pool sizes of 5:1 (five samples: one positive, four negative) and 10:1. An automated workflow was used to generate pool sizes of 3:1, 4:1, 5:1, 8:1 and 10:1. The impact of pool size, pooling method, and assay chemistry on sensitivity, specificity, and lower limit of detection (LLOD) was evaluated. Both the Hologic Aptima® and Panther Fusion® SARS-CoV-2 assays demonstrated >85% positive percent agreement between neat testing and pool sizes ≤5:1, satisfying FDA recommendation. Discordant results between neat and pooled testing were more frequent for positive samples with CT>35. Fusion® CT (cycle threshold) values for pooled samples increased as expected for pool sizes of 5:1 (CT increase of 1.92 - 2.41) and 10:1 (CT increase of 3.03 - 3.29). The Fusion® assay demonstrated lower LLOD than the Aptima® assay for pooled testing (956 vs 1503 cp/mL, pool size of 5:1). Lowering the cut-off threshold of the Aptima® assay from 560 kRLU (manufacturer's setting) to 350 kRLU improved the assay sensitivity to that of the Fusion® assay for pooled testing. Both Hologic's SARS-CoV-2 assays met the FDA recommended guidelines for percent positive agreement (>85%) for pool sizes ≤5:1. Automated pooling increased test throughput and enabled automated sample tracking while requiring less labor. The Fusion® SARS-CoV-2 assay, which demonstrated a lower LLOD, may be more appropriate for surveillance testing.</p>
Pool Table (Animation)
A billiard table or billiards table is a bounded table on which cue sports are played. In the modern era, all billiards tables (whether for carom billiards, pocket billiards, pyramid or snooker) provide a flat surface usually made of quarried slate, that is covered with cloth (usually of a tightly-woven worsted wool called baize), and surrounded by vulcanized rubber cushions, with the whole elevated above the floor.:115, 238 More specific terms are used for specific sports, such as snooker table and pool table, and different-sized billiard balls are used on these table types. An obsolete term is billiard board, used in the 16th and 17th centuries. Info Link: https://en.wikipedia.org/wiki/Billiard_table I have a Patreon Join now! :https://www.patreon.com/user?u=14434838 Source: Objaverse 1.0 / Sketchfab
MBKS Swimming Pool, Kuching, Sarawak #OSS
Formerly known as the [KMC Swimming Pool](https://goo.gl/maps/duwY2mpyCyNLashM7), this iconic place is significant to many Kuchingites, as the first public and affordable swimming pool where we learnt to swim! As [Kuching has been recognised as a Creative City of Gastronomy under the UNESCO Creative Cities Network (UCCN)](https://www.thestar.com.my/news/nation/2021/11/18/kuching-is-first-malaysian-city-on-unesco039s-creative-cities-list-for-gastronomy), the Redevelopment of this iconic swimming pool into a [Water Fun Park & Centre for UNESCO Creative City of Gastronomy](https://www.youtube.com/watch?v=K13sSJox0FQ) has been [launched by our CM / Premier](https://dayakdaily.com/mbks-swimming-pool-into-gastronomy-centre-transformation-marks-beginning-of-further-upgrading-kuching-city/) [Check out other parts of Sarawak through our Aerial Panoramic Views](https://www.google.com.my/maps/contrib/110626466326541263095/photos/@1.6886212,110.0592046,11.29z/data=!3m1!4b1!4m3!8m2!3m1!1e1) #opensourcesarawak #borneo Source: Objaverse 1.0 / Sketchfab
Light Data Lehanagh Pool IMTA lab Ireland.
<p> HOBO Pendant® MX2202 data loggers were deployed on site to monitor light intensity (in lux = lumens/m2).</p>
Data from: Drosophila medulla neuroblast termination via apoptosis, differentiation and gliogenic switch is scheduled by the depletion of the neuroepithelial stem cell pool
<p>The brain is consisted of diverse neurons arising from a limited number of neural stem cells. <em>Drosophila</em> neural stem cells called neuroblasts (NBs) produces specific neural lineages of various lineage sizes depending on their location in the brain. In the <em>Drosophila</em> visual processing centre - the optic lobes (OLs), medulla NBs derived from the neuroepithelium (NE) give rise to neurons and glia cells of the medulla cortex. The timing and the mechanisms responsible for the cessation of medulla NBs are so far not known. In this study, we show that the termination of medulla NBs during early pupal development is determined by the exhaustion of the NE stem cell pool. Hence, altering NE-NB transition during larval neurogenesis disrupts the timely termination of medulla NBs. Medulla NBs terminate neurogenesis via a combination of apoptosis, terminal symmetric division via Prospero, and a switch to gliogenesis via Glial Cell Missing (Gcm), however, these processes occur independently of each other. We also show that temporal progression of the medulla NBs is mostly not required for their termination. As the <em>Drosophila</em> OL shares a similar mode of division with mammalian neurogenesis, understanding when and how these progenitors cease proliferation during development can have important implications for mammalian brain size determination and regulation of its overall function.</p>
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.