Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
3,655
datasets available to search
ShareScore release 0.9.0
Dataset results
3,655 results for “Structural data”
Data for the "Discovery of Dehydroamino Acid Residues in the Capsid and Matrix Structural Proteins of HIV-1"
<p>Bottom-up mass spectrometry-based proteomic analysis (trypsin) was performed on four biological replicates of HIV-1 virions. These virions were isolated from HEK293T cells transfected with a HIV-1 proviral plasmid derived from the pNL4-3 molecular clone, rendered biosafe due to inactivating point mutations in both the env and vpr reading frames. There are 8 total spectra, 4 are from unlabeled aliquots of sample, and 4 are from aliquots of sample treated with glutathione to label dehydroamino acids (Spectra can be accessed on MassIVE (MSV000088220). All data was analyzed using MetaMorpheus version 0.0.319 (https://github.com/smith-chem-wisc/MetaMorpheus). Provided here are the results of this analysis.</p>
Supporting Data for Drift Phase Structure Implications for Radiation Belt Transport by T.P. O'Brien et al. submitted to J. Geophysical Res.
<p>Datasets used in Drift Phase Structure Implications for Radiation Belt Transport by T.P. O'Brien et al. submitted to J. Geophysical Res.</p>
Raw data for: A model for the formation and evolution of structure of initial loess deposits
<p>The dataset includes the monitoring results of volumetric water content and matric suction during wetting and drying processes of initial loess deposits. The data are used for Figure 3 in the manuscript “A model for the formation and evolution of structure of initial loess deposits” (submitted to Geophysical Research Letters).</p>
Data from: Chrysolaena obovata, A SPECIES NATIVE OF BRAZILIAN CERRADO: GENETIC DIVERSITY AND STRUCTURE OF NATURAL POPULATIONS AND POTENTIAL FOR INULIN PRODUCTION
<p><em>Chrysolaena obovata</em> (Less.) M. Dematteis, an herbaceous Asteraceae species widely distributed across different Brazilian Cerrado physiognomies, has underground organs, named rhizophores, that accumulate high concentrations of inulin-type fructans. These carbohydrates are recognized as beneficial soluble fibers for human health and are currently used in the food and pharmaceutical industries. Considering that fructans, in addition to their economic potential, provide plants with greater tolerance to drought, heat and cold, it is important to understand whether their metabolism is conserved in natural populations. In this work, we aimed to investigate if the levels of genetic diversity in the populations studied allow the selection of localities with a high genetic base and higher fructan content for future programs of <em>in</em> <em>situ</em> conservation and genetic improvement for inulin production. Therefore, we characterized the diversity, structure, and gene flow of seven natural populations from Brazilian Cerrado, using nine microsatellite loci (SSR). In addition, we compared whether the fructan composition varied between populations of different Cerrado phytophysiognomies. Overall, we found that <em>C. obovata</em> populations exhibited moderate levels of genetic diversity, low genetic differentiation, and high gene flow. This study identified two populations with less genetic diversity and therefore, greater attention should be given to conservation programs including these populations. Fructan metabolism is conserved in all populations, indicating that <em>C. obovata</em> is an important genetic resource with high potential for inulin production.</p> <p><strong>File descriptions</strong></p> <p>Population_code.txt - Contains a matrix that indicates the population_code, Population_name, Brazilian-state, Phytophysiognomy, Collection coordinates and Altitudes (m).</p> <p>Date_ Diaz et al.xlsx – Contains Genotypes crude of the individuals analyzed. Primer used for nine microsatellite loci (Camacho <em>et al</em> 2017). </p> <p>Carbohydrates_Diaz et al - Contains data for carbohydrates in <em>C. obovata</em> plant rhizophores in each population (BRA, UB, SD, SP).</p> <p><strong>Location: Brazilian Cerrado</strong></p>
Data and code: Climate policy accelerates structural changes in energy employment
<p>The file contains code to create the figures used in main text and supplementary information of the paper <strong>Climate policy accelerates structural changes in energy employment</strong>.</p> <p>To run the RMD file and see the resulting figures, press Knit on R studio (requires the package knitr), or else see the attached HTML file, already created through such a process.</p>
Dataset: "Joint structural annotation of small molecules using liquid chromatography retention order and tandem mass spectrometry data"
<p>Dataset used in the experiments of the publication: "Joint structural annotation of small molecules using liquid chromatography retention order and tandem mass spectrometry data" by Bach et al.</p> <p><strong>File description:</strong></p> <ul> <li> <p>cfmid4.tar: MS² spectra simulated using <a href="https://bitbucket.org/wishartlab/cfm-id-code/src/CFM-ID_4.0.7/">CFM-ID (v4.0.7)</a> for all molecular candidate structures</p> </li> <li> <p>db_layout.png: Visualization of the SQLite database (DB) layout</p> </li> <li> <p>massbank.sqlite.gz: DB containing all needed data to (re-)run the experiments shown in the paper. Please read "DB_README.md" for further details. The database file can be unpacked using gzip.</p> </li> <li> <p>metfrag.tar: MetFrag input files and MS² scores for all candidate sets computed using the <a href="https://ipb-halle.github.io/MetFrag/projects/metfragcl/">MetFrag software</a>.</p> </li> <li> <p>sirius_scores.tar: MS² scores for all candidates and measured spectra using the <a href="https://bio.informatik.uni-jena.de/software/sirius/">SIRIUS software</a>.</p> </li> <li> <p>sirius_inputs.tar: Input (ms-files) for the SIRIUS software.</p> </li> <li> <p>DB_README.md: Description of each table in the "massbank.sqlite" SQLite DB.</p> </li> <li> <p>db_processing_scripts.tar: Scripts to re-produce the "massbank.sqlite" and a README.md providing further information on the process.</p> </li> <li> <p>massbank__2020.11__v0.6.1.sqlite: Base SQLite DB from which the "massbank.sqlite" was build up. It was created using the "<a href="https://github.com/bachi55/massbank2db">massbank2db</a>" (v0.6.1) Python package using the <a href="https://github.com/bachi55/MassBank-data/tree/2020.11-branch">MassBank release 2020.11</a>.</p> </li> <li> <p>substructure_fingerprints.tar: Pre-computed substructure counting fingerprints for all candidates related to our experiments.</p> </li> </ul> <p><strong>Instructions:</strong></p> <p>The "massbank.sqlite" can be directly used with the Structure Support Vector Machine Model (SSVM) described in the manuscript and implemented in the "<a href="https://github.com/aalto-ics-kepaco/msms_rt_ssvm">ssvm</a>" Python package.</p> <p>If desired, the database can be re-produced using the scripts provided in "db_processing_scripts.tar":</p> <ol> <li>Create a directory for all data</li> <li>Download and extract the ... <ol> <li>Processing scripts</li> <li>MS² scorer outputs (e.g. metfrag.tar)</li> <li>Pre-computed substructure fingerprints</li> </ol> </li> <li>Follow the instructions given in the "README.md" of the "db_processing_scripts.tar"</li> </ol>
Longitudinal structural MRI, MRS, and behavioral data for mice prenatally exposed to maternal immune activation at gestational day 9
<p>Previous evidence from our lab (https://cobralab.ca/) and others suggest that prenatal exposure to maternal immune activation (MIA) can impact trajectories of neurodevelopment as measured through brain anatomy and behavior in mice. Yet, there are still open questions regarding the alterations to developmental trajectories, as well as the impact on brain chemistry, that this data set seeks to explore. The dataset presented here includes magnetic resonance imaging (MRI) and magnetic resonance spectroscopy (MRS) data from two timepoints, adolescence (postnatal day [PND 35]) and young adulthood (PND 60) in C57BL/6J mice prenatally exposed either to poly I:C (POL) inducing maternal immune activation (MIA) or saline (SAL) at gestational day (GD) 9. The dataset also includes three behaviors acquired after each scanning session with 2 days of rest between the scans and each behavior: open field test, social novel object preference test, and prepule inhibition. Finally, the data also include cytokine assays acquired from a separate sample of pregnant mice and a test-retest of MRS acquired from a voxel in the anterior cingulate area. </p> <p>The data here published were collected and analyzed for a paper under review, available as a preprint where more details can be found here: https://www.preprints.org/manuscript/202203.0136/v1. In brief, using whole-brain, voxelwise analysis techniques (deformation-based morphometry) we found MIA subtly altered developmental trajectories, reducing volume relative to SAL offspring in the hippocampus and the anterior, right caudate putamen, and increasing volume in the posterior, left caudate putamen and cerebellum. Additionally, there was a trending decrease of myo-inositol and GABA in MIA offspring at PND 60 compared to SAL controls. Finally, there was a trending decrease in ratio of distance travelled in the anxiogenic center zone of an open field compared to the outer areas at PND 35 for MIA offspring. </p> <p>In this dataset you will find a total of <strong>80 preprocessed structural MRIs</strong> in minc format acquired at postnatal day ~35 and ~60 in mice exposed to 5mg/kg poly I:C or vehicle control (0.9% sterile saline) at GD9. The images are included in CUPO_MIA_mncs.zip. These are T1-weighted structural images with two averages; repetition time (TR)/echo time (TE) = 21.55 ms/5.13 ms, matrix size = 260 x 158 x 210, voxel dimensions =&thinsp;70 µm isotropic, flip angle =&thinsp;20°, 23 min total using 5% isoflurane for induction, 1.5% for maintenance of anesthesia during the scan on a cryogenically-cooled surface coil. T1-weighted scans were preprocessed by stripping native coordinates, flipping left-right to maintain fidelity, denoising, correcting inhomogeneities in the bias field using the N4 algorithm, and registering in LSQ6 alignment (i.e. 6 degrees of freedom are allowed for imagine alignment: translations and rotations along x, y, and z dimensions). The demographics information for each animal is included in the <strong>demographics.csv</strong> file. </p> <p>Behavioural tests were performed following the postnatal day 35 and 60 scans in all animals with a 2 day rest period. These include: open field test, three chambered social approach, and prepulse inhibition. The data for all of these tests is presented in individual .csv spreadsheet and includes data for both the timepoints evaluated. Additionally, cytokine panels were collected from an independent cohort of 7 dams. <strong>MRS </strong>data are included in two formats: 1) preprocessed quantifications from LCModel software in csvs, and 2) raw data with press and press_w (respectively water supressed and unsupressed acquisitions) for analysis. The raw data were released in upload version 1.1.0. MRS was acquired from a 1.2 x 2.6 x 2.5 mm3 voxel in the ACA with a Point Resolved Spectroscopy sequence (PRESS; TR/TE=3000/8.5 ms, 256 averages). Within the raw_data.zip,</p> <p>Included in this data set are the structural MRIs in MINC format, the behavioural .csv data, the MRS data (csvs and raw files), and a <strong>README</strong> file providing further detail on the data structure and content, and on how to interpret the data column titles. DICOMS are also available for the structural MRI data, as are the raw (not-preprocessed) MINC files, available upon request to the authors. </p>
Data from: Drastic shift in flowering phenology of F1 hybrids explains the population structure of Imperata cylindrica in Japan
<p>Hybridization is a major source of phenotypic variation and a driving force for evolution. On the other hand, these novel traits can often disrupt adaptive relationships between the parental phenotypes and their environments. However, it remains unclear how new hybrid traits disrupt local adaptation. Here, we report how a new phenotype of hybrids between two ecotypes of Imperata cylindrica contributes to rapid reproductive isolation from their parents and affects hybrid fitness.</p> <p>We analyzed 350 accessions of I. cylindrica collected from the 1980s to the 2010s throughout Japan to explore the genetic population structure of the hybrids. We surveyed flowering periods, seed sets, and germination of two ecotypes and their hybrids in both natural habitats and common gardens.</p> <p>Genetic analyses of population structure revealed that the hybrid populations consisted of only F1 individuals, without post-F1 hybrids. The flowering phenology of the F1 plants was delayed to autumn, 5–6 months later than the parental ecotypes.</p> <p>The drastic shift in flowering phenology prevents F1s from backcrossing. In addition, it changes their seed dispersal time to winter. Germination is inhibited by low temperatures, and the seeds likely decay before the next spring, resulting in the absence of an F2 generation. For the first time in the field, we found environmental mismatch of F1 as a specific mechanism for the maintenance of only F1 populations.</p> <p>Synthesis. We have demonstrated that this flowering phenology mismatch promotes reproductive isolation between the parents and F1s and affects various temporal components of the hybrids, resulting in a unique hybrid population consisting only of F1s. This system sheds light on the importance of hybrid traits in terms of rapid reproductive isolation.</p>
Interactive Causal Structure Discovery with Hyytiälä measurements (experiment code and data)
<p>This archive contains code and data required to reproduce the results presented in the following two papers.</p> <p>Interactive Causal Structure Discovery in Earth System Sciences<br> published in Proceedings of The KDD'21 Workshop on Causal Discovery, 2021.</p> <p>Technical note: incorporating expert domain knowledge into causal structure discovery workflows<br> published in Biogeosciences, 2022</p> <p>The archive contains a README markdown document detailing the contents and how to run the experiments.</p> <p> </p>
Data and code for Winter conditions structure extratropical patterns of species richness of amphibians, birds, and mammals globally
<p>This repository contains the dataset analyzed in 'Winter conditions structure extratropical patterns of species richness of amphibians, birds, and mammals globally' - published in the journal Global Ecology and Biogeography - and the R code used to generate the correlations, generalized additive models, and related figures presented in the manuscript. Column descriptions for the data can be found in the associated README.txt file. Please refer to the manuscript for further detail on the variables and how they were derived.</p> <p>The Winter Indices (WIs) were derived using satellite remote sensing data from optical (MODIS, snow cover) and microwave (MEaSUREs freeze/thaw, frozen ground) sensors. The species richness maps were derived using IUCN range maps for individual species of amphibians, birds, and mammals (data requests can be made here: <a href="https://www.iucnredlist.org/resources/spatial-data-download">https://www.iucnredlist.org/resources/spatial-data-download</a>). Climatic varibales were derived from WorldClim v2.0 data, elevation from USGS GMTED2010 data, and primary productivity from the cumulative dynamic habitat index available here: <a href="http://silvis.forest.wisc.edu/maps-data/">http://silvis.forest.wisc.edu/maps-data/</a>.</p>
Data from "CO Line Emission Surfaces and Vertical Structure in Mid-Inclination Protoplanetary Disks"
<p>CO line emission image cubes ("[DISK]_CO_cube.fits"), line+continuum image cubes ("[DISK]_CO_cube_wcont.fits"), and zeroth moment maps ("[DISK]_CO_M0.fits") associated with Law et al., 2022, "CO Line Emission Surfaces and Vertical Structure in Mid-Inclination Protoplanetary Disks," The Astrophysical Journal</p> <p>CO line emission image cubes from the DSHARP ALMA Large Program (for HD 142666, MY Lup, GW Lup, WaOph 6, DoAr 25) can be found at: https://bulk.cv.nrao.edu/almadata/lp/DSHARP/ and are not included here.</p> <p>The raw data are available on the ALMA archive (see Table 1 in the paper for a listing of the relevant ALMA project codes).</p>
Scale dependent spatial structuring of mountain river large bed elements maximizes flow resistance - Data Revision
<p>Datasets and R code related to manuscript entitled, "Scale dependent spatial structuring of mountain river large bed elements maximizes flow resistance". See '0_READ_ME.rtf' file for additional description of available files.</p>
Gauge structure of the Einstein field equations in Bondi-like coordinates: convergence tests data
<p>This dataset is the result of the runs performed for the paper "Gauge structure of the Einstein field equations in Bondi-like coordinates". The data can be used to reproduce the convergence plots, as well as to compare with the data obtained if one performs the same runs independently.</p> <p> </p> <p>To perform independently the runs that produce the data, the PITTNullCode included has to be used. More details on how to proceed with this can be found in the ancillary files of https://arxiv.org/abs/2111.14794 at the directory "anc/numerics/README".</p>
IGM Population of HFF structures using Hi-C, laminB1 DamID, 3D HIPMAp FISH and single cell SPRITE data
<p>This repository accompanies the manuscript "<strong>Integrative Genome Modeling Platform reveals essentiality of rare contact events in 3D genome organizations</strong>", to appear in Nat. Methods (2022), see also https://www.biorxiv.org/content/10.1101/2021.08.22.457288v1.</p> <p>It contains the preprocessed input data files (Hi-C, laminB1 DamID, 3D HIPMAp FISH and single cell SPRITE) for the HFF fibroblast cell line to be used in the Integrative Genome Modeling platform (IGM) developed in the Alber lab at UCLA (https://github.com/alberlab/igm).</p> <p>Also, we provide the configuration file to run IGM with those datasets, as we did in generating the HDSF population discussed in the accompanying manuscript. Such population is also provided as an "hss" file. Documentation and a simple demo/tutorial on how IGM can be run is given on the Alber lab Github @ https://github.com/alberlab/igm.</p> <p>All files can be read in using the <em>h5py</em> and <em>alabtools</em> (available @https://github.com/alberlab/alabtools) Python packages. More detailed information is provided in the manuscript and associated Supplementary Information file. </p> <p>For any inquiry/suggestions/doubts please reach out to Lorenzo Boninsegna (bonimba@g.ucla.edu) or Dr. Frank Alber (falber@g.ucla.edu).</p> <p> </p>
Structural conversion of α-synuclein at the mitochondria induces neuronal toxicity; Image data
<p>Lists of image sets included in <strong>"Structural conversion of α-synuclein at the mitochondria induces neuronal toxicity"</strong></p> <p> </p> <p>Duplex-1 and Duplex-2 Images</p> <p>Amyloid Fibril TIRFM Images (SNCA-A53T ImagesTIRF Images)</p> <p>TEM Fibril Images</p> <p>DLS Images </p> <p>SMLM Images 1 & 2</p> <p> </p> <p>CLEM Images</p> <ul> <li>FIB SEM Images (videos)</li> <li>TEM Images </li> </ul> <p> </p> <p>Live-cell imaging</p> <ul> <li>Superoxide Images</li> <li>MitoTracker® Red Images</li> <li>Membrane Potential (TMRM) Images </li> <li>Ca 2+ Images</li> <li>NADH Autofluorescence Images</li> <li>Cell Death Images</li> <li>Amytracker Images</li> <li>Cardiolipin Images</li> <li>FRET Images</li> </ul>
Data set for the journal article Structural Analysis of Metal Coordination Sites in Single-Atom Catalysts Based on Carbon Nitrides
<p>The data is organized according to the figure in the manuscript. </p>
Data for the manuscript: Demographic basis of spatially structured fluctuations in a threespine stickleback metapopulation
<p>Uncovering the demographic basis of population fluctuations is a central goal of population biology. This is particularly challenging for spatially structured populations, which require disentangling synchrony in demographic rates from coupling via immigration. In this study, we fit a stage-structured metapopulation model to a 29-year times series of threespine stickleback abundance in the heterogeneous and productive Lake Myvatn, Iceland. The lake comprises two basins (North and South) connected by a channel through which the stickleback disperse. The model includes time-varying demographic rates, allowing us to assess the potential contributions of recruitment and survival, spatial coupling via immigration, and demographic transience to the population's large fluctuations in abundance. Our analyses indicate that recruitment was only modestly synchronized between the two basins, whereas survival probabilities of adults were more strongly synchronized, contributing to cyclic fluctuations in the lake-wide population size with a period of approximately six years. The analyses further show that the two basins are coupled through immigration, with the North Basin subsidizing the South Basin and playing a dominant role in driving the lake-wide dynamics. Our results show that cyclic fluctuations of a metapopulation can be explained in terms of the combined effects of synchronized demographic rates and spatial coupling.</p>
Data and code repository for Science Advances submission: Uncovering the biological basis of control energy: structural and metabolic correlates of energy inefficiency in temporal lobe epilepsy
<p>Data and codes related to the findings reported in the manuscript, "Uncovering the biological basis of control energy: structural and metabolic correlates of energy inefficiency in temporal lobe epilepsy", are deposited. Please refer to the notes located within each folder for further descriptions.</p>
Transformed crane data from: Balancing structural complexity with ecological insight in spatio-temporal species distribution models
<p>The potential for statistical complexity in species distribution models (SDMs) has greatly increased with advances in computational power. Structurally complex models provide the flexibility to analyse intricate ecological systems and realistically messy data, but can be difficult to interpret, reducing their practical impact. Founding model complexity in ecological theory can improve insight gained from SDMs. </p> <p>Here, we evaluate a marked point process approach, which uses multiple Gaussian random fields to represent population dynamics of the Eurasian crane (<em>Grus grus</em>) in a spatio-temporal species distribution model. We discuss the role of model components and their impacts on predictions, in comparison with a simpler binomial presence/absence approach. Inference is carried out using Integrated Nested Laplace Approximation (INLA) with inlabru, an accessible and computationally efficient approach for Bayesian hierarchical modelling, which is not yet widely used in SDMs. </p> <p>Using the marked point process approach, crane distribution was predicted to be dependent on the density of suitable habitat patches, as well as close to observations of the existing population. This demonstrates the advantage of complex model components in accounting for spatio-temporal population dynamics (such as habitat preferences and dispersal limitations) that are not explained by environmental variables. However, including an AR1 temporal correlation structure in the models resulted in unrealistic predictions of species distribution; highlighting the need for careful consideration when determining the level of model complexity.</p> <p>Increasing model complexity, with careful evaluation of the effects of additional model components, can provide a more realistic representation of a system, which is of particular importance for a practical and impact-focused discipline such as ecology (though these methods extend to applications for a wide range of systems). Founding complexity in contextual theory is not only fundamental to maintaining model interpretability, but can be a useful approach to improving insight gained from model outputs. </p>
Research data in support of: An Interplay of Mechanical and Structural Properties of DNA Determines Its Electrostatic Interactions with Lipids
<p>The data collected and reported for the publication entitled: An Interplay of Mechanical and Structural Properties of DNA Determines Its Electrostatic Interactions with Lipids. by Diana Morzy et al.</p> <p>Data is divided by the technique used, with folders named accordingly. Each dataset has a readme file, explaining the basic technical details, as well as how to open each file type.</p> <p>Please do not hesitate to contact the corresponding author (MMCB) for further details.</p>
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.