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ShareScore release 0.9.0
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231 results for “avian influenza”
Data from: Determining the phylogenetic and phylogeographic origin of highly pathogenic avian influenza (H7N3) in Mexico
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Data from: Juveniles and migrants as drivers for seasonal epizootics of avian influenza virus
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Data from: Demographic and spatiotemporal patterns of avian influenza infection at the continental scale, and in relation to annual life cycle of a migratory host
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Data from: Subtype diversity and reassortment potential for co-circulating avian influenza viruses at a diversity hot spot
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Data from: Range-wide genetic population structure of common pochard (Aythya ferina): a potentially important vector of highly pathogenic avian influenza viruses
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Data from: Wild birds affected by Highly Pathogenic Avian Influenza A(H5N1) worldwide: Epidemiological insights into the recent panzootic
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Data from: Pathobiological features favoring the intercontinental dissemination of highly pathogenic avian influenza virus
Avian influenza viruses (AIV) are a continued threat to global health and economy. Unlike other highly pathogenic AIV, novel H5N8 disseminated very quickly from Korea to other areas in Asia, Europe, and even North America following its first outbreak in 2014. However, the pathobiological features of the virus that favored its global translocation remain unknown. In this study, we used a compartmental model to examine the avian epidemiological characteristics that would support the geographic spread of influenza by bird migration, and to provide recommendations for AIV surveillance in wild bird populations. We simulated virus transmission and translocation in a migratory bird population while varying four system properties: 1) contact transmission rate; 2) infection recovery rate; 3) mortality rate induced by infection; and 4) migratory recovery rate. Using these simulations, we then calculated extinction and translocation probabilities for influenza during spring migration as a function of the altered properties. We find that lower infection recovery rates increase the likelihood of AIV translocation in migratory bird populations. In addition, lower mortality rates or migration recovery rates also favor translocation. Our results identify pathobiological features supporting AIV intercontinental dissemination risk and suggest that characteristic differences exist among H5N8 and other AIV subtypes that have not translocated as rapidly (e.g. H5N6 and H5N1).
Data from: Migration strategy affects avian influenza dynamics in mallards (Anas platyrhynchos)
Studies of pathogen transmission typically overlook that wildlife hosts can include both migrant and resident populations when attempting to model circulation. Through the application of stable isotopes in flight feathers, we estimated the migration strategy of mallards (Anas platyrhynchos) - resident, intermediate-distance migrant or long-distance migrant, occurring on California wintering grounds. Our study demonstrates that mallards, a principal host of avian influenza virus (AIV) in nature, contribute differently to virus gene flow depending on migration strategy. No difference in AIV prevalence was detected between resident (9.6%), intermediate-distance (9.6%) and long-distance migrants (7.4%). Viral diversity among the three groups was also comparable, possibly owing to viral pool mixing when birds converge at wetlands during winter. These findings challenge the view that migratory animals are exposed to a higher number and diversity of pathogens. However, migrants and residents contributed differently to the virus gene pool at wintering wetlands. Migrants introduced virus from northern breeding grounds (Alaska and the NW Pacific Rim) into the wintering population, facilitating gene flow at continental scales, but circulation of imported virus appeared to be limited. In contrast, resident mallards acted as AIV reservoirs facilitating year-round circulation of limited subtypes (i.e. H5N2) at lower latitudes. This study supports a model of virus exchange in temperate regions driven by the convergence of wild birds with separate geographic origins and exposure histories.
Data from: Ecosystem interactions underlie the spread of avian influenza A viruses with pandemic potential
Despite evidence for avian influenza A virus (AIV) transmission between wild and domestic ecosystems, the roles of bird migration and poultry trade in the spread of viruses remain enigmatic. In this study we integrate ecosystem interactions into a phylogeographic model to assess the contribution of wild and domestic hosts to AIV distribution and persistence. Analysis of globally sampled AIV datasets shows frequent two-way transmission between wild and domestic ecosystems. In general, viral flow from domestic to wild bird populations was restricted to within a geographic region. In contrast, spillover from wild to domestic populations occurred both within and between regions. Wild birds mediated long-distance dispersal at intercontinental scales whereas viral spread among poultry populations was a major driver of regional spread. Viral spread between poultry flocks frequently originated from persistent lineages circulating in regions of intensive poultry production. Our analysis of long-term surveillance data demonstrates that meaningful insights can be inferred from integrating ecosystem into phylogeographic reconstructions that may be consequential for pandemic preparedness and livestock protection.
Association of poultry vaccination with interspecies transmission and molecular evolution of H5 subtype avian influenza virus
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Avian influenza mutations analysis - data
<p>Datasets of avian influenza mutations</p>
AI results complementing the 2020 Annual Report on surveillance for Avian Influenza in poultry and wild birds in Member States of the European Union - Luxembourg
<p>This dataset contains the results of the EU co-funded surveillance activities conducted in 2020, which consisted of:</p> <ul> <li>Serological surveys to monitor the circulation of AIV subtypes H5 and H7 in poultry (active surveillance). These surveys should preferentially target poultry species or production systems with increased risk for introduction of avian influenza (AI).</li> <li>Passive surveillance aiming at the virological detection of AI in wild birds found dead or moribund.</li> </ul>
China Case Control Avian Influenza
ClinicalTrials.gov study NCT00428753. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Data from: Migration strategy affects avian influenza dynamics in mallards (Anas platyrhynchos)
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Data from: Ecosystem interactions underlie the spread of avian influenza A viruses with pandemic potential
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Data from: A synchronized global sweep of the internal genes of modern avian influenza virus
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Data from: The persistence of multiple strains of avian influenza in live bird markets
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Data from: Pathobiological features favoring the intercontinental dissemination of highly pathogenic avian influenza virus
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MicroRNA profiling of H9N2 subtype avian influenza virus-infected chicken dendritic cells using high-throughput sequencing
GEO Series GSE147658. Gallus gallus. 6 samples. Type: Non-coding RNA profiling by high throughput sequencing.
Transcriptomes of several organs of lean and obese mice infected with avian influenza
GEO Series GSE134685. Mus musculus. 48 samples. Type: Expression profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.