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334 results for “biological evaluation”
Figure 3 from: Al-Mahadeen MM, Jaber AM, Al-Najjar BO (2024) Design, synthesis and biological evaluation of novel 2-hydroxy-1 H-indene-1,3(2 H)-dione derivatives as FGFR1 inhibitors. Pharmacia 71: 1-9. https://doi.org/10.3897/pharmacia.71.e122127
Figure 3 Stick representation of a. Erdafitinib; b. 7b; c. 9a; d. 9b; e. 9c in grey colour, docked within FGFR1 (PDB ID: 5EW8) binding site (green). Generated by Biovia Discovery Studio visualizer®.
Figure 2 from: Al-Mahadeen MM, Jaber AM, Al-Najjar BO (2024) Design, synthesis and biological evaluation of novel 2-hydroxy-1 H-indene-1,3(2 H)-dione derivatives as FGFR1 inhibitors. Pharmacia 71: 1-9. https://doi.org/10.3897/pharmacia.71.e122127
Figure 2 Solid ribbon representation of FGFR1 (PDB ID: 5EW8) with co-crystal (grey) and re-docked (orange) erdafitinib. Generated by Biovia Discovery Studio visualizer®.
Figure 4 from: Al-Mahadeen MM, Jaber AM, Al-Najjar BO (2024) Design, synthesis and biological evaluation of novel 2-hydroxy-1 H-indene-1,3(2 H)-dione derivatives as FGFR1 inhibitors. Pharmacia 71: 1-9. https://doi.org/10.3897/pharmacia.71.e122127
Figure 4 Dose-response curves of compounds 7b, 9a, 9b and 9c FGFR1 inhibitor. A. Dose-response curve of 7b with IC50 = 3.1 μM; B. Dose-response curve of 9a with IC50 = 5.7 μM; C. Dose-response curve of 9b with IC50 = 3.3 μM; D. Dose-response curve of 9c with IC50 = 4.1 μM.
Figure 19 in The suprageneric groups of the Pimplinae (Hymenoptera: Ichneumonidae): a cladistic re-evaluation and evolutionary biological study
Figure 19. Cladogram resulting from secondary analysis: section 6 (of 9), the Camptotypus genus-group. Note that unlike in the primary analysis (Figure 7) both Hemipimpla and Camptotypus are monophyletic, although the monophyly of Zonopimpla is not supported. The relative positions of Camptotypus + Hemipimpla and Odontopimpla + Clydonium are reversed.
Figure 16 in The suprageneric groups of the Pimplinae (Hymenoptera: Ichneumonidae): a cladistic re-evaluation and evolutionary biological study
Figure 16. Cladogram resulting from secondary analysis: section 3 (of 9), the Pimplini. note that unlike the primary analysis (Fig. 3) the Theronia genus-group is strongly monophyletic and the sister-lineage to the higher Pimplini. All genera within the Theronia genus-group are resolved as monophyletic except Theronia s.s., as are all genera within the Pimpla genus-group, including Apechthis, Alophopimpla and Itoplectis. Strongylopsis and Echthromorpha are placed within the Xanthopimpla genus-group (see also Fig. 17).
Figure 13 in The suprageneric groups of the Pimplinae (Hymenoptera: Ichneumonidae): a cladistic re-evaluation and evolutionary biological study
Figure 13. Cladogram resulting from primary analysis: section 13 (of 13), subset 2, the terminal taxa of the Polysphincta genus-complex. Note that although Pterinopus, Eruga and Acrodactyla are monophyletic, Polysphincta is polyphyletic (see also Figs 11, 12).
Figures 65–70 in The suprageneric groups of the Pimplinae (Hymenoptera: Ichneumonidae): a cladistic re-evaluation and evolutionary biological study
Figures 65–70. Stereoscan photographs of Pimplinae. Figs 65–69, tergite II, dorsal; 65, Dolichomitus irritator; 66, Liotryphon crassiseta; 67, Pseudopimpla pygidiator; 68, Clydonium gallicola; 69, Pimpla isidroi. Fig. 70, Dolichomitus irritator, hind tarsal claw of ♀, internal view.
Figures 91–93. Hind tarsomeres 2–5 in The suprageneric groups of the Pimplinae (Hymenoptera: Ichneumonidae): a cladistic re-evaluation and evolutionary biological study
Figures 91–93. Hind tarsomeres 2–5 of female; 91, Neotheronia mellosa; 92, Pimpla sumichrasti; 93, Acrotaphus tibialis.
Figure 5 in The suprageneric groups of the Pimplinae (Hymenoptera: Ichneumonidae): a cladistic re-evaluation and evolutionary biological study
Figure 5. Cladogram resulting from primary analysis: section 5 (of 13), the Pimpla genus-group of the higher Pimplini. Note that Echthromorpha, Strongylopsis and Pimpla are monophyletic, as is the clade comprising Alophopimpla + Itoplectis + Apechthis, but that the recognition of Apechthis renders Itoplectis paraphyletic.
Figure 8 from: Jochum A, Slapnik R, Klussmann-Kolb A, Páll-Gergely B, Kampschulte M, Martels G, Vrabec M, Nesselhauf C, Weigand AM (2015) Groping through the black box of variability: An integrative taxonomic and nomenclatural re-evaluation of Zospeum isselianum Pollonera, 1887 and allied species using new imaging technology (Nano-CT, SEM), conchological, histological and molecular data (Ellobioidea, Carychiidae). Subterranean Biology 16: 123-165. https://doi.org/10.3897/subtbiol.16.5758
Figure 8 - NanoCT−SEM Plate 2. A–F Zospeum isselianum, neotype (CSR SASA 37013), Turjeva jama G–H Zospeum isselianum (SMNH 2216), Jama na Zgornjih Brsnikih I–L Zospeum sp. (CSR SASA 37698a), Konečka zijalka.
Figure 2 from: Jochum A, Slapnik R, Klussmann-Kolb A, Páll-Gergely B, Kampschulte M, Martels G, Vrabec M, Nesselhauf C, Weigand AM (2015) Groping through the black box of variability: An integrative taxonomic and nomenclatural re-evaluation of Zospeum isselianum Pollonera, 1887 and allied species using new imaging technology (Nano-CT, SEM), conchological, histological and molecular data (Ellobioidea, Carychiidae). Subterranean Biology 16: 123-165. https://doi.org/10.3897/subtbiol.16.5758
Figure 2 - Historical material: A Zospeum isselianum syntype (MZUT M3232): upper mountains of Natisone River valley B–F Zospeum isselianum topotype: Turjeva jama G–P Specimens labelled as "Zospeum alpestre" in the Bourguignat Collection (MHNG 7898/2) from "Cav[erne]. de Carniole".
Figure 17 from: Jochum A, Slapnik R, Klussmann-Kolb A, Páll-Gergely B, Kampschulte M, Martels G, Vrabec M, Nesselhauf C, Weigand AM (2015) Groping through the black box of variability: An integrative taxonomic and nomenclatural re-evaluation of Zospeum isselianum Pollonera, 1887 and allied species using new imaging technology (Nano-CT, SEM), conchological, histological and molecular data (Ellobioidea, Carychiidae). Subterranean Biology 16: 123-165. https://doi.org/10.3897/subtbiol.16.5758
Figure 17 - Light micrograph of a section of the reproductive tract of Zospeum sp. (Konečka zijalka) (CSR SASA 21675). A Gonad (g) with acinus of the ovotestis including the germinal epithelial ring (ger) surrounding the acinar lumina (al), sustentacular cells (Sertoli cells) (sc) and oogonia (og) B Digestive gland (dg), hermaphroditic duct (hd) lined with cilia (c), posterior loop of the intestine (pi), receptaculum seminis (rs) containing allospermatozoa with spermatozoa oriented towards and apical ends touching the epithelial cells, and long motile cilia (ce) of intestine (i).
Figure 16 from: Jochum A, Slapnik R, Klussmann-Kolb A, Páll-Gergely B, Kampschulte M, Martels G, Vrabec M, Nesselhauf C, Weigand AM (2015) Groping through the black box of variability: An integrative taxonomic and nomenclatural re-evaluation of Zospeum isselianum Pollonera, 1887 and allied species using new imaging technology (Nano-CT, SEM), conchological, histological and molecular data (Ellobioidea, Carychiidae). Subterranean Biology 16: 123-165. https://doi.org/10.3897/subtbiol.16.5758
Figure 16 - Light micrograph of the histological appearance of the digestive tract of Zospeum sp. (Konečka zijalka) (CSR SASA 21675). A−B Bilobed muscular gizzard (mg) with epithelium showing columnar cells (cc) with microvillous apical surfaces (mv), posterior loop of the intestine (pi) with ciliated epithelium (ce) B Elaborate muscular plates (mp), thick cuticle (cu), highly ciliated rectum (r), gastric pouch (gp), digestive gland (dg) and hermaphroditic duct.
Figure 14 from: Jochum A, Slapnik R, Klussmann-Kolb A, Páll-Gergely B, Kampschulte M, Martels G, Vrabec M, Nesselhauf C, Weigand AM (2015) Groping through the black box of variability: An integrative taxonomic and nomenclatural re-evaluation of Zospeum isselianum Pollonera, 1887 and allied species using new imaging technology (Nano-CT, SEM), conchological, histological and molecular data (Ellobioidea, Carychiidae). Subterranean Biology 16: 123-165. https://doi.org/10.3897/subtbiol.16.5758
Figure 14 - Images of the radula of Zospeum isselianum (Turjeva jama) (CSR SASA 37013 conspecific) and Zospeum sp. (Konečka zijalka) (CSR SASA 21675). A−D SEM of the radular ribbon of topotypic Zospeum isselianum A Radular ribbon showing adhesive layer of contact zone with odontophore B SEM overview showing rachidian teeth (r) and lateral teeth (l) C Rows of lateral teeth bearing fine medial groove D Marginal teeth E Light micrograph showing the histological appearance of the radular sheath of Zospeum sp. (Konečka zijalka) showing the inferior epithelium (ie) attached to the radular membrane (rm) mineralizing cells (mc) with degenerating nuclei and radular teeth (rt).
Figure 4 from: Jochum A, Slapnik R, Klussmann-Kolb A, Páll-Gergely B, Kampschulte M, Martels G, Vrabec M, Nesselhauf C, Weigand AM (2015) Groping through the black box of variability: An integrative taxonomic and nomenclatural re-evaluation of Zospeum isselianum Pollonera, 1887 and allied species using new imaging technology (Nano-CT, SEM), conchological, histological and molecular data (Ellobioidea, Carychiidae). Subterranean Biology 16: 123-165. https://doi.org/10.3897/subtbiol.16.5758
Figure 4 - Overview of morphological assignments, molecular species delimitation results and integrative taxonomic treatment of each of the four clusters, which are indicated by the longitudinal black bars for either the ABDG or the SP approach. Numbers indicate individual specimens; ABGD = Automatic Barcode Gap Discovery; SP = Statistical Parsimony.
Figure 13 from: Jochum A, Slapnik R, Klussmann-Kolb A, Páll-Gergely B, Kampschulte M, Martels G, Vrabec M, Nesselhauf C, Weigand AM (2015) Groping through the black box of variability: An integrative taxonomic and nomenclatural re-evaluation of Zospeum isselianum Pollonera, 1887 and allied species using new imaging technology (Nano-CT, SEM), conchological, histological and molecular data (Ellobioidea, Carychiidae). Subterranean Biology 16: 123-165. https://doi.org/10.3897/subtbiol.16.5758
Figure 13 - A Light micrograph showing the histological appearance of Zospeum sp. (Konečka zijalka) (CSR SASA 21675) with the mantel cavity (mc), mucus glands (mg), oesophagus (oe) bearing thick cuticular sheath (cs) and leading into the crop (c), the buccal ganglia (bg), and the cephalopodial portion of the reproductive system including penis (p) and vas deferens (vd) B Paired cerebral ganglia united by the cerebral commissure situated just dorsal to the origin of the oesophagus in the buccal mass.
Figure 12 from: Jochum A, Slapnik R, Klussmann-Kolb A, Páll-Gergely B, Kampschulte M, Martels G, Vrabec M, Nesselhauf C, Weigand AM (2015) Groping through the black box of variability: An integrative taxonomic and nomenclatural re-evaluation of Zospeum isselianum Pollonera, 1887 and allied species using new imaging technology (Nano-CT, SEM), conchological, histological and molecular data (Ellobioidea, Carychiidae). Subterranean Biology 16: 123-165. https://doi.org/10.3897/subtbiol.16.5758
Figure 12 - Light micrograph showing histological overview of the digestive system of Zospeum sp. (Konečka zijalka) (CSR SASA 21675). A Mouth and buccal apparatus. Mouth slit between oral lappets (m), crescent-shaped jaw (j), radula (r), pharynx (ph), digestive gland (dg), intestine (i), kidney (k), columellar muscle (cm), and pedal ganglia (peg) B Mantle gland (mag), sigmoid intestine (si), radular sac (rs), cerebral ganglion (cg), mucus glands (mg), kidney (k), heart showing auricle and ventricle (h), digestive gland (dg), columellar muscle (cm), oesophagus (oe) and salivary glands (sg).
Figure 7 from: Jochum A, Slapnik R, Klussmann-Kolb A, Páll-Gergely B, Kampschulte M, Martels G, Vrabec M, Nesselhauf C, Weigand AM (2015) Groping through the black box of variability: An integrative taxonomic and nomenclatural re-evaluation of Zospeum isselianum Pollonera, 1887 and allied species using new imaging technology (Nano-CT, SEM), conchological, histological and molecular data (Ellobioidea, Carychiidae). Subterranean Biology 16: 123-165. https://doi.org/10.3897/subtbiol.16.5758
Figure 7 - Kimura−2-parameter (K2P) genetic distance table in %. Delineated species are marked with boxes. For each individual specimen, its morphospecies designation and genetic distance data to all remaining specimens are given.
Figure 11 from: Jochum A, Slapnik R, Klussmann-Kolb A, Páll-Gergely B, Kampschulte M, Martels G, Vrabec M, Nesselhauf C, Weigand AM (2015) Groping through the black box of variability: An integrative taxonomic and nomenclatural re-evaluation of Zospeum isselianum Pollonera, 1887 and allied species using new imaging technology (Nano-CT, SEM), conchological, histological and molecular data (Ellobioidea, Carychiidae). Subterranean Biology 16: 123-165. https://doi.org/10.3897/subtbiol.16.5758
Figure 11 - Type and shell images Plate 5: A–E Zospeum kupitzense holotype: (SMF 256354) F–H Zospeum kupitzense (SMNH 3291), Ložekarjeva zijalka I–M Zospeum amoenum (RS59), Potočka zijalka.
Figure 10 from: Jochum A, Slapnik R, Klussmann-Kolb A, Páll-Gergely B, Kampschulte M, Martels G, Vrabec M, Nesselhauf C, Weigand AM (2015) Groping through the black box of variability: An integrative taxonomic and nomenclatural re-evaluation of Zospeum isselianum Pollonera, 1887 and allied species using new imaging technology (Nano-CT, SEM), conchological, histological and molecular data (Ellobioidea, Carychiidae). Subterranean Biology 16: 123-165. https://doi.org/10.3897/subtbiol.16.5758
Figure 10 - NanoCT−SEM Plate 4. A–F Zospeum kupitzense (RS3291), Ložekarjeva zijalka G. Zospeum alpestre (SMNH 2216), Kamniška jama H, I−L Zospeum isselianum Ihanščica cave J−K Zospeum amoenum (RS59), Potočka zijalka.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.