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305
datasets available to search
ShareScore release 0.9.0
Dataset results
305 results for “characterization model”
Multi-omics characterization of inflammatory bowel disease induced hyperplasia/dysplasia in the Rag2-/- / Il10-/- mouse model [RNA-Seq]
GEO Series GSE163036. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Generation and Characterization of Lung Cancer PDX Models from Human Specimens Across Serial Passages
GEO Series GSE295073. Mus musculus; Homo sapiens. 2 samples. Type: Expression profiling by high throughput sequencing.
Single cell RNAseq characterization of cell types produced over time in an in vitro model of human inhibitory interneuron differentiation.
GEO Series GSE93593. Homo sapiens. 1733 samples. Type: Expression profiling by high throughput sequencing.
Functional and genomic characterization of a xenograft model system for the study of metastasis in triple-negative breast cancer
GEO Series GSE111705. Homo sapiens. 4 samples. Type: Genome variation profiling by SNP array.
Characterization of an E2f1 acetylation-deficient knock-in mouse model by RNA-Seq profiling
GEO Series GSE135360. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.
Characterization of 5-aminolevulinic acid and radiation dose effects on radiotherapy using mouse tumor model.
GEO Series GSE92972. Mus musculus. 22 samples. Type: Expression profiling by array.
Eye lens organoids going simple: characterization of a new model
GEO Series GSE228547. Mus musculus. 15 samples. Type: Expression profiling by high throughput sequencing.
Identification and characterization of metastasis-initiating cells in esophageal squamous cell carcinoma in a pulmonary metastasis mouse model [scRNA-Seq]
GEO Series GSE249057. Homo sapiens. 5 samples. Type: Expression profiling by high throughput sequencing.
Functional and Transcriptomic Characterization of iPSC-derived Macrophages and their Application in Modeling Mendelian Disease
GEO Series GSE55536. Homo sapiens. 33 samples. Type: Expression profiling by high throughput sequencing.
Characterization of the chromatin accessibility in an Alzheimer’s disease (AD) mouse model (ATAC-Seq)
GEO Series GSE145906. Mus musculus. 6 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Sub-population RNAseq characterization of cell types produced over time in an in vitro model of human inhibitory interneuron differentiation.
GEO Series GSE93801. Homo sapiens. 40 samples. Type: Expression profiling by high throughput sequencing.
Molecular Characterization of a Precision-Cut Rat Liver Slice Model for the Evaluation of Anti-Fibrotic Compounds
GEO Series GSE120804. Rattus norvegicus. 48 samples. Type: Expression profiling by high throughput sequencing.
Using human stem cell derived in vitro modeling to characterize the effect of MYCN overexpression on early hSAP development and tumor formation
GEO Series GSE245729. Homo sapiens. 2 samples. Type: Expression profiling by high throughput sequencing.
Molecular characterization of a precision-cut rat lung slice model for the evaluation of anti-fibrotic drugs
GEO Series GSE120679. Rattus norvegicus. 36 samples. Type: Expression profiling by high throughput sequencing.
Functional genomics of the human epididymis: further characterization of efferent ducts and model systems by single cell RNA-seq analysis.
GEO Series GSE235009. Homo sapiens. 4 samples. Type: Expression profiling by high throughput sequencing.
Identification and characterization of metastasis-initiating cells in esophageal squamous cell carcinoma in a pulmonary metastasis mouse model
GEO Series GSE249058. Homo sapiens. 7 samples. Type: Expression profiling by high throughput sequencing.
Development and Characterization of Syngeneic Orthotopic Transplant Models of Obesity-Responsive Triple-Negative Breast Cancer in C57BL/6J Mice (in vivo)
GEO Series GSE272328. Mus musculus. 24 samples. Type: Expression profiling by array.
A pore-scale 3D dynamic morphological modeling and physical characterization of hydrate-bearing sediment based on computed tomography images
<p><strong>Introduction</strong></p> <p>This supporting information includes one figure S1, which is the representative elemental volume (REV) used in this study. And the figure S1 is consisted of 300 slices with a voxel size of 4.4 μm. There are two phases in the REV: the sand and the pore.</p> <p> </p> <p>Figure S1 is uploaded with file name Figure S1-REV300.am, which is the representative elemental volume (REV) used in this study</p>
Pore-scale 3D dynamic morphological modeling and physical characterization of hydrate-bearing sediment based on computed tomography images
<p>This supporting information includes one Figure-S1-REV300, which is the representative elemental volume (REV) used in this study. And the Figure-S1-REV300 is 300*300*300 with a voxel size of 4.4 μm. There are two phases in the REV: the sand and the pore.</p> <p>Figure S1 is uploaded with file name Figure S1-REV300.tif, which is the representative elemental volume (REV) used in this study</p>
Data from: Using a multi-stage hESC model to characterize BDE-47 toxicity during neurogenesis
While the ramifications associated with polybrominated diphenyl ethers (PBDE) exposures during human pregnancy have yet to be determined, increasing evidence in humans and animal models suggests that these compounds cause neurodevelopmental toxicity. Human embryonic stem cell models (hESCs) can be used to study the effects of environmental chemicals on the successive stages of neuronal development. Here, using a hESC differentiation model, we investigated the effects of common PBDE congeners (BDE-47 or -99) on the successive stages of early neuronal development. First, we determined the points of vulnerability to PBDEs across four stages of in vitro neural development by using assays to assess for cytotoxicity. Differentiated neural progenitors were identified to be more sensitive to PBDEs than their less differentiated counterparts. In follow-up investigations, we observed BDE-47 to inhibit functional processes critical for neurogenesis (e.g., proliferation, migration) in hESC-derived neural precursor cells (NPCs) at sub-lethal concentrations. Finally, to determine the mechanism(s) underlying PBDE-toxicity, we conducted global transcriptomic and methylomic analyses of BDE-47. We identified 589 genes to be differentially expressed (DE) due to BDE-47 exposure, including molecules involved in oxidative stress mediation, cell cycle, hormone signaling, steroid metabolism, and neurodevelopmental pathways. In parallel analyses, we identified a significant increase in CpG methylation. In summary, our results suggest, on a cellular level, PBDEs induce human neurodevelopmental toxicity in a concentration-dependent manner and sensitivity to these compounds is dependent on the developmental stage of exposure. Proposed mRNA and methylomic perturbations may underlie toxicity in early embryonic neuronal populations.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.