Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
669
datasets available to search
ShareScore release 0.9.0
Dataset results
669 results for “comparative genomics”
Figure 1 from: He X, Hsu WH, Hou R, Yao Y, Xu Q, Jiang D, Wang L, Wang H (2020) Comparative genomics reveals bamboo feeding adaptability in the giant panda (Ailuropoda melanoleuca). ZooKeys 923: 141-156. https://doi.org/10.3897/zookeys.923.39665
Figure 1 The enrichment analysis of shared genes between the giant panda and mammalian species with different feeding habits. Giant pandas have the characteristics of both carnivores and herbivores. Studies show that it is close to carnivores in perception and close to herbivores in physiological functions. The abscissa is the pair value of the corrected p value, and the corrected p < 0.05 is taken as the threshold value. a shared genes between the giant panda and other mammalian species with different feeding habits b gene enrichment analysis of the giant panda and carnivores c gene enrichment analysis of the giant panda and herbivores.
Supplementary material 1 from: Hu C, Wang S, Huang B, Liu H, Xu L, Hu Z, Liu Y (2020) The complete mitochondrial genome sequence of Scolopendra mutilans L. Koch, 1878 (Scolopendromorpha, Scolopendridae), with a comparative analysis of other centipede genomes. ZooKeys 925: 73-88. https://doi.org/10.3897/zookeys.925.47820
Table S1
Figure 2 from: Hu C, Wang S, Huang B, Liu H, Xu L, Hu Z, Liu Y (2020) The complete mitochondrial genome sequence of Scolopendra mutilans L. Koch, 1878 (Scolopendromorpha, Scolopendridae), with a comparative analysis of other centipede genomes. ZooKeys 925: 73-88. https://doi.org/10.3897/zookeys.925.47820
Figure 2 Variation in length and base composition of each of the 13 core protein coding genes (PCGs) among eight centipedes' mitochondrial genomes A PCG length variation B GC content across PCGsC AT skew D GC skew.
Figure 4 from: Hu C, Wang S, Huang B, Liu H, Xu L, Hu Z, Liu Y (2020) The complete mitochondrial genome sequence of Scolopendra mutilans L. Koch, 1878 (Scolopendromorpha, Scolopendridae), with a comparative analysis of other centipede genomes. ZooKeys 925: 73-88. https://doi.org/10.3897/zookeys.925.47820
Figure 4 A Molecular phylogeny of eight centipede species based on Maximum Likelihood inference analysis of 13 protein-coding genes (PCGs) B Traditional morphological classification based on the position of spiracles and the variation of larvae.
Figure 1 from: Hu C, Wang S, Huang B, Liu H, Xu L, Hu Z, Liu Y (2020) The complete mitochondrial genome sequence of Scolopendra mutilans L. Koch, 1878 (Scolopendromorpha, Scolopendridae), with a comparative analysis of other centipede genomes. ZooKeys 925: 73-88. https://doi.org/10.3897/zookeys.925.47820
Figure 1 Mitochondrial genome map of the Scolopendra mutilans. Genes drawn inside the circle are transcribed clockwise, and those outside are counterclockwise. PCGs are shown as brown arrows, rRNA genes as green arrows, tRNA genes as pink arrows. The innermost circle shows the GC content. GC content is plotted as the deviation from the average value of the entire sequence.
Figure 3 from: Hu C, Wang S, Huang B, Liu H, Xu L, Hu Z, Liu Y (2020) The complete mitochondrial genome sequence of Scolopendra mutilans L. Koch, 1878 (Scolopendromorpha, Scolopendridae), with a comparative analysis of other centipede genomes. ZooKeys 925: 73-88. https://doi.org/10.3897/zookeys.925.47820
Figure 3 Mitogenome synteny among eight centipede species. Synteny analyses were generated in Mauve 2.4.0. A total of six large homologous regions were identified among the eight mitogenomes, while the sizes and relative positions of the homologous fragments varied across the mitogenomes.
Comparative Genomics to Metabolomics in the genus Nocardia
<p>BiGScape network files</p>
Supplemental to Masterthesis: Comparative Genome analysis of borontolerant and -sensitive bacterial isolates
<p>Supplemental data and result files of the Masterthesis: Comparative Genome analysis of borontolerant and -sensitive bacterial isolates</p>
Supplementary material 4 from: Wu Y-A, Gao J-W, Cheng X-F, Xie M, Yuan X-P, Liu D, Song R (2020) Characterization and comparative analysis of the complete mitochondrial genome of Azygia hwangtsiyui Tsin, 1933 (Digenea), the first for a member of the family Azygiidae. ZooKeys 945: 1-16. https://doi.org/10.3897/zookeys.945.49681
Figure S1
Supplementary material 1 from: Wu Y-A, Gao J-W, Cheng X-F, Xie M, Yuan X-P, Liu D, Song R (2020) Characterization and comparative analysis of the complete mitochondrial genome of Azygia hwangtsiyui Tsin, 1933 (Digenea), the first for a member of the family Azygiidae. ZooKeys 945: 1-16. https://doi.org/10.3897/zookeys.945.49681
Table S1
Supplementary material 3 from: Wu Y-A, Gao J-W, Cheng X-F, Xie M, Yuan X-P, Liu D, Song R (2020) Characterization and comparative analysis of the complete mitochondrial genome of Azygia hwangtsiyui Tsin, 1933 (Digenea), the first for a member of the family Azygiidae. ZooKeys 945: 1-16. https://doi.org/10.3897/zookeys.945.49681
Table S3
Supplementary material 2 from: Wu Y-A, Gao J-W, Cheng X-F, Xie M, Yuan X-P, Liu D, Song R (2020) Characterization and comparative analysis of the complete mitochondrial genome of Azygia hwangtsiyui Tsin, 1933 (Digenea), the first for a member of the family Azygiidae. ZooKeys 945: 1-16. https://doi.org/10.3897/zookeys.945.49681
Table S2
Supplementary material 5 from: Wu Y-A, Gao J-W, Cheng X-F, Xie M, Yuan X-P, Liu D, Song R (2020) Characterization and comparative analysis of the complete mitochondrial genome of Azygia hwangtsiyui Tsin, 1933 (Digenea), the first for a member of the family Azygiidae. ZooKeys 945: 1-16. https://doi.org/10.3897/zookeys.945.49681
Figure S2
Figure 2 from: Wu Y-A, Gao J-W, Cheng X-F, Xie M, Yuan X-P, Liu D, Song R (2020) Characterization and comparative analysis of the complete mitochondrial genome of Azygia hwangtsiyui Tsin, 1933 (Digenea), the first for a member of the family Azygiidae. ZooKeys 945: 1-16. https://doi.org/10.3897/zookeys.945.49681
Figure 2 Phylogenetic relationships and gene arrangement of Azygia hwangtsiyui with other selected digeneas based on translated mitochondrial proteins. The concatenated amino-acid sequence datasets of the 12 protein-coding genes were analyzed by Bayesian Inference (BI) and Maximum Likelihood (ML), utilizing Cloacotaenia megalops (NC_032295.1) and Dibothriocephalus latus (NC_008945.1) as the outgroups. Both ML and BI analyses constructed identical tree topologies.
Supplementary material 1 from: Zhongying Q, Huihui C, Hao Y, Yuan H, Huimeng L, Xia L, Xingchun G (2020) Comparative mitochondrial genomes of four species of Sinopodisma and phylogenetic implications (Orthoptera, Melanoplinae). ZooKeys 969: 23-42. https://doi.org/10.3897/zookeys.969.49278
Tables S1–S7
Figure 3 from: Zhongying Q, Huihui C, Hao Y, Yuan H, Huimeng L, Xia L, Xingchun G (2020) Comparative mitochondrial genomes of four species of Sinopodisma and phylogenetic implications (Orthoptera, Melanoplinae). ZooKeys 969: 23-42. https://doi.org/10.3897/zookeys.969.49278
Figure 3 The long polythymine stretch and conserved sequence blocks in the A+T rich regions from four species. Note: The long polythymine stretch. T-stretch sequence was labelled with box, located in the majority strand. Within each block, nucleotides identical in the two sequences are bottom-marked with asterisks.
Supplementary material 2 from: Zhongying Q, Huihui C, Hao Y, Yuan H, Huimeng L, Xia L, Xingchun G (2020) Comparative mitochondrial genomes of four species of Sinopodisma and phylogenetic implications (Orthoptera, Melanoplinae). ZooKeys 969: 23-42. https://doi.org/10.3897/zookeys.969.49278
Figures S1–S4
Data from: Comparative genomics of the nonlegume Parasponia reveals insights into evolution of nitrogen-fixing rhizobium symbioses
Nodules harboring nitrogen-fixing rhizobia are a well-known trait of legumes, but nodules also occur in other plant lineages, with rhizobia or the actinomycete Frankia as microsymbiont. It is generally assumed that nodulation evolved independently multiple times. However, molecular-genetic support for this hypothesis is lacking, as the genetic changes underlying nodule evolution remain elusive. We conducted genetic and comparative genomics studies by using Parasponia species (Cannabaceae), the only nonlegumes that can establish nitrogen-fixing nodules with rhizobium. Intergeneric crosses between Parasponia andersonii and its nonnodulating relative Trema tomentosa demonstrated that nodule organogenesis, but not intracellular infection, is a dominant genetic trait. Comparative transcriptomics of P. andersonii and the legume Medicago truncatula revealed utilization of at least 290 orthologous symbiosis genes in nodules. Among these are key genes that, in legumes, are essential for nodulation, including NODULE INCEPTION (NIN) and RHIZOBIUM-DIRECTED POLAR GROWTH (RPG). Comparative analysis of genomes from three Parasponia species and related nonnodulating plant species show evidence of parallel loss in nonnodulating species of putative orthologs of NIN, RPG, and NOD FACTOR PERCEPTION. Parallel loss of these symbiosis genes indicates that these nonnodulating lineages lost the potential to nodulate. Taken together, our results challenge the view that nodulation evolved in parallel and raises the possibility that nodulation originated ∼100 Mya in a common ancestor of all nodulating plant species, but was subsequently lost in many descendant lineages. This will have profound implications for translational approaches aimed at engineering nitrogen-fixing nodules in crop plants.
Data from: Comparative genomics, infectivity and cytopathogenicity of Zika viruses produced by acutely and persistently Zika virus-infected human hematopoietic cell lines
Zika virus (ZIKV), an arthropod-borne virus, has emerged as a major human pathogen. Prolonged or persistent ZIKV infection of human cells and tissues may serve as a reservoir for the virus and present serious challenges to the safety of public health. Human hematopoietic cell lines with different developmental properties revealed differences in susceptibility and outcomes to ZIKV infection. In 3 separate studies involving the prototypic MR 766 ZIKV strain and the human monocytic leukemia U937 cell line, ZIKV initially developed only a low-grade infection at a slow rate. After continuous culture for several months, persistently ZIKV-infected cell lines were observed with most, if not all, cells testing positive for ZIKV antigen. The infected cultures produced ZIKV RNA (v-RNA) and infectious ZIKVs persistently ("persistent ZIKVs") with distinct infectivity and pathogenicity when tested using various kinds of host cells. When the genomes of ZIKVs from the three persistently infected cell lines were compared with the genome of the prototypic MR 766 ZIKV strain, distinct sets of mutations specific to each cell line were found. Significantly, all three "persistent ZIKVs" were capable of infecting fresh U937 cells with high efficiency at rapid rates, resulting in the development of a new set of persistently ZIKV-infected U937 cell lines. The genomes of ZIKVs from the new set of persistently ZIKV-infected U937 cell lines were further analyzed for their different mutations. The 2nd generation of persistent ZIKVs continued to possess most of the distinct sets of mutations specific to the respective 1st generation of persistent ZIKVs. We anticipate that the study will contribute to the understanding of the fundamental biology of adaptive mutations and selection during viral persistence. The persistently ZIKV-infected human cell lines that we developed will also be useful to investigate critical molecular pathways of ZIKV persistence and to study drugs or countermeasures against ZIKV infections and transmission.
Data from: The aggregate site frequency spectrum (aSFS) for comparative population genomic inference
Understanding how assemblages of species responded to past climate change is a central goal of comparative phylogeography and comparative population genomics, and an endeavor that has increasing potential to integrate with community ecology. New sequencing technology now provides the potential to gain complex demographic inference at unprecedented resolution across assemblages of non-model species. To this end, we introduce the aggregate site frequency spectrum (aSFS), an expansion of the site frequency spectrum to use single nucleotide polymorphism (SNP) datasets collected from multiple, co-distributed species for assemblage-level demographic inference. We describe how the aSFS is constructed over an arbitrary number of independent population samples and then demonstrate how the aSFS can differentiate various multi-species demographic histories under a wide range of sampling configurations while allowing effective population sizes and expansion magnitudes to vary independently. We subsequently couple the aSFS with a hierarchical approximate Bayesian computation (hABC) framework to estimate degree of temporal synchronicity in expansion times across taxa, including an empirical demonstration with a dataset consisting of five populations of the threespine stickleback (Gasterosteus aculeatus). Corroborating what is generally understood about the recent post-glacial origins of these populations, the joint aSFS/hABC analysis strongly suggests that the stickleback data are most consistent with synchronous expansion after the Last Glacial Maximum (posterior probability = 0.99). The aSFS will have general application for multi-level statistical frameworks to test models involving assemblages and/or communities and as large-scale SNP data from non-model species become routine, the aSFS expands the potential for powerful next-generation comparative population genomic inference.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.