Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
1,988
datasets available to search
ShareScore release 0.9.0
Dataset results
1,988 results for “proliferation”
AEG-1 inhibits proliferation and invasion of colorectal cancer HCT116 cells via the PI3K/AKT/mTOR pathway
Open the record for dataset details and reuse information.
Eupatorin modulates BCPAP in thyroid cancer cell proliferation via suppressing the NF-κB/P13K/AKT signaling pathways
Open the record for dataset details and reuse information.
Figure 2 in Optimizing in vitro factors for improvement of shoot proliferation of 'Flordaguard' peach rootstock
Figure 2. Shoot proliferation from node explant of 'Flordaguard' peach rootstock. A. Shoot cultured in half strength MS (½N); B. full strength MS medium; C. Induction of multiple shoots in full strength MS supplemented with 0.5 mg L-1 of BAP; D. induction of multiple shoots in half strength MS (½N) supplemented with 0.5 mg L-1 of BAP.
Figure 1 in Optimizing in vitro factors for improvement of shoot proliferation of 'Flordaguard' peach rootstock
Figure 1. Order of the factors tested for improvement in the in vitro multiplication of 'Flordaguard' peach rootstock. I. Salt medium composition in 4 mg L-1 BAP; II. Salt medium composition in 0.5 mg L-1 BAP; III. Culture medium consistency; IV. Explant type and position; and V. Explant growth in half strength MS medium with different BAP doses.
Figure 1. H&E in Resveratrol-Tempeh reduce micronucleus frequencies bone marrow cells and stimulate osteocyte proliferation in aluminum chloride-induced mice
Figure 1. H&E staining of the femur bone mice. (A) untreated-group, 10X20; (B) Al-treated group 10X10; (C) Al+Res5-treated group, 10X10 and (D) Al+Res10-treated group, 10X10. Green star: Bone trabecular, Blue arrow: osteocytes, Red arrow: empety lacunae.
AEG-1 inhibits proliferation and invasion of colorectal cancer HCT116 cells via the PI3K/AKT/mTOR pathway
Open the record for dataset details and reuse information.
Dancing in Unpredictable Times: Cashinahua celebrations for life proliferation and climate change
Open the record for dataset details and reuse information.
Retroviral transduction, cell proliferation assay and myeloid colony formation assay
<p><strong>Retroviral </strong><strong>t</strong><strong>ransduction</strong><strong>, cell proliferation assay </strong><strong>and </strong><strong>m</strong><strong>yeloid </strong><strong>c</strong><strong>olony </strong><strong>f</strong><strong>ormation </strong><strong>a</strong><strong>ssay</strong></p>
Fig. 1 in Effects of Roscovitine on Schedule of Divisional Morphogenesis, Basal Bodies Proliferation and Cell Divisions in Tetrahymena thermophila
Fig. 1. Divisional morphogenesis and cytokinesis in untreated (control) T. thermophila. Cells were immunostained with the anti-centrin 20H5 antibody. A–F' stomatogenesis, stages I–VI; G–H cytokinesis. AF – an anarchic field, ARF – parental apical ring of filaments, mARF material for new ARF localised on in the proximal ends (couplets of BBs) of cortical rows in opisthe cell, FZ – fission zone, OA1 and OA2 – parental and new oral apparatuses, OC – parental oral crescent, nOC – new oral crescents in both daughter cells. Bar: 10 µm for A–H.
Fig. 11 in Effects of Roscovitine on Schedule of Divisional Morphogenesis, Basal Bodies Proliferation and Cell Divisions in Tetrahymena thermophila
Fig. 11. Cortical structures of T. thermophila immunogoldlabelled with anti-cdc14A antibody. A – longitudinal section of the ciliated basal body; B – transversal section of the fragment of the cortical row; C – section at the level of basal bodies of oral membranelle. Kt – kinetodesmal fiber, pc – postciliary microtubules, arrowhead – filamentous material. Bar: 1 μm.
Fig. 3 in Effects of Roscovitine on Schedule of Divisional Morphogenesis, Basal Bodies Proliferation and Cell Divisions in Tetrahymena thermophila
Fig. 3. Divisional morphogenesis and cytokinesis in T. thermophila after 5.5 h treatment with roscovitine. Cells were immunostained with the anti-centrin 20H5 antibody. A–C – stage VI of divisional morphogenesis; D–F' – cytokinesis; A and A' – ventral and dorsal views of the same cell. Other explanations as in Fig. 1. Bar in F': 10 µm for A–F'.
Distinct melanocyte subpopulations defined by stochastic expression of proliferation or maturation programs enable a rapid and sustainable pigmentation response
Open the record for dataset details and reuse information.
CircRPPH1 promotes cell proliferation, migration and invasion of non-small cell lung cancer (NSCLC) via the PI3K/AKT and JAK2/STAT3 signaling axes
<p>original numerical data before creating graphs</p>
Data from: Retrotransposon proliferation coincident with the evolution of dioecy in asparagus
Current phylogenetic sampling reveals that dioecy and an XY sex chromosome pair evolved once or possibly twice in the genus Asparagus. Although there appear to be some lineage-specific polyploidization events, the base chromosome number of 2n=2x=20 is relatively conserved across the Asparagus genus. Regardless, dioecious species tend to have larger genomes than hermaphroditic species. Here we test whether this genome size expansion in dioecious species is related to a polyploidization and subsequent chromosome fusion or retrotransposon proliferation in dioecious species. We first estimate genome sizes or use published values for four hermaphrodites and four dioecious species distributed across the phylogeny and show that dioecious species typically have larger genomes than hermaphroditic species. Utilizing a phylogenomic approach we find no evidence for ancient polyploidization contributing to increased genome sizes of sampled dioecious species. We do find support for an ancient whole genome duplication event predating the diversification of the Asparagus genus. Repetitive DNA content of the four hermaphroditic and four dioecious species was characterized based on randomly sampled whole genome shotgun sequencing and common elements were annotated. Across our broad phylogenetic sampling, Ty-1 Copia retroelements in particular have undergone a marked proliferation in dioecious species. In the absence of a detectable whole genome duplication event, retrotransposon proliferation is the most likely explanation for the precipitous increase in genome size in dioecious Asparagus species.
Data from: Tungsten blocks murine B lymphocyte differentiation and proliferation through downregulation of IL-7 receptor/Pax5 signaling
Tungsten is an emerging environmental toxicant associated with several pediatric leukemia clusters, although a causal association has not been established. Our previous work demonstrated that tungsten exposure resulted in an accumulation of pre-B cells in the bone marrow, the same cell type that accumulates in pediatric acute lymphoblastic leukemia (ALL). To better understand the relevant molecular mechanisms, we performed RNA sequencing on flow sorted pre-B cells from control and tungsten-exposed mice. Tungsten decreased the expression of multiple genes critical for B cell development, including members of the IL-7R and pre-BCR signaling pathways, such as Jak1, Stat5a, Erb1, Pax5, Syk, and Ikzf3. These results were confirmed in an in vitro model of B cell differentiation, where tungsten arrested differentiation at the pro-B cell stage and inhibited proliferation. These changes were associated with decreased expression of multiple genes in the IL-7R signaling pathway and decreased percentage of IL-7R, phosphorylated STAT5 (pSTAT5) double-positive cells. Supplementation with IL-7 or overexpression of Pax5, the transcription factor downstream of IL-7R, rescued the tungsten-induced differentiation block. Together, these data support the hypothesis that IL-7R/Pax5 signaling axis is critical to tungsten-mediated effects on pre-B cell development. Importantly, many of these molecules are modulated in ALL.
Ascorbic acid ameliorates corneal endothelial dysfunction and enhances cell proliferation via the noncanonical GLUT1-ERK axis
<p>The datasets supporting the conclusions of the article submitting.</p>
Figure 1 in The study of exposure times and dose-escalation of tick saliva on mouse embryonic stem cell proliferation
Figure 1. Effect of H. marginatum SGE (0-160 µg/ml) on mouse embryonic stem cell proliferation and viability. Values represent relative fold change of cell viability normalized to untreated negative control. The Geisser –Greenhouse correction and Dunnett´s test on multiple comparison were used. The results are mean ± standard deviation (SD) from a representative experiment carried out in triplicate and were seeded in equal amount in 3 different 96 -well cultured plates.
Significance of Synbiotics on Inflammation and Proliferation of Colonic Mucosa
ClinicalTrials.gov study NCT01534572. IPD Sharing: Not stated. Countries: 0. Publications: 1.
Mirena® IUD's Effect on Fallopian Tube Fimbriae and Ovarian Cortical Inclusion Cyst Cell Proliferation
ClinicalTrials.gov study NCT02477202. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Oral Contraceptive (OC) Estrogen Dose and Breast Proliferation
ClinicalTrials.gov study NCT01318005. IPD Sharing: Not stated. Countries: 1. Publications: 0.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.