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214
datasets available to search
ShareScore release 0.9.0
Dataset results
214 results for “quantitative traits”
Porcine intramuscular fat content and composition are regulated by quantitative trait loci with muscle-specific effects
GEO Series GSE25708. Sus scrofa. 19 samples. Type: Expression profiling by array.
System genetics in rat HXB/BXH reference population identifies Tti2 as a pleiotropic quantitative trait gene for adult hippocampal neurogenesis and serum glucose
GEO Series GSE160361. Rattus norvegicus. 40 samples. Type: Expression profiling by high throughput sequencing.
Quantitative trait loci mapped for TCF21 binding, chromatin accessibility and chromosomal looping in coronary artery smooth muscle cells reveal molecular mechanisms of coronary disease loci
GEO Series GSE141752. Homo sapiens. 18 samples. Type: Genome binding/occupancy profiling by high throughput sequencing; Other; SNP genotyping by SNP array; Genome variation profiling by SNP array.
Heterochromatin is a quantitative trait locus associated with spontaneous epiallele formation
GEO Series GSE171157. Arabidopsis thaliana. 1 samples. Type: Methylation profiling by high throughput sequencing.
Genetic identification, replication, and functional fine-mapping of expression quantitative trait loci in primary human liver tissue [Illumina SNP array]
GEO Series GSE26105. Homo sapiens. 224 samples. Type: Genome variation profiling by SNP array; SNP genotyping by SNP array.
Enrichment of inflammatory bowel disease and colorectal cancer risk variants in colon expression quantitative trait loci
GEO Series GSE56789. Homo sapiens. 40 samples. Type: Expression profiling by array.
Quantitative trait loci mapped for TCF21 binding, chromatin accessibility and chromosomal looping in coronary artery smooth muscle cells reveal molecular mechanisms of coronary disease loci (ATAC-Seq)
GEO Series GSE141748. Homo sapiens. 1 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Characterization of expression quantitative trait loci in extensively phenotyped pedigrees from Colombia and Costa Rica
GEO Series GSE82042. Homo sapiens. 786 samples. Type: Expression profiling by array.
The contribution of RNA decay quantitative trait loci to inter-individual variation in steady-state gene expression levels
GEO Series GSE37451. Homo sapiens. 350 samples. Type: Expression profiling by array.
Genetic effects on chromatin accessibility uncover mechanisms of liver gene regulation and quantitative traits
GEO Series GSE264684. Homo sapiens. 477 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Quantitative trait loci (QTL) study identifies novel genomic regions associated to Chiari-Like Malformation in Griffon Bruxellois dogs
GEO Series GSE52221. Canis lupus familiaris. 80 samples. Type: Genome variation profiling by SNP array; SNP genotyping by SNP array.
Molecular Quantitative Trait Locus Mapping In Human Endothelial Cells Identifies Regulatory SNPs Underlying Gene Expression and Complex Disease Traits
GEO Series GSE139377. Homo sapiens. 504 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Identification of expression quantitative trait loci (eQTL) in human liver
GEO Series GSE32504. Homo sapiens. 149 samples. Type: Expression profiling by array.
Genome-wide identification of expression quantitative trait loci (eQTLs) in human heart: gene expression
GEO Series GSE55231. Homo sapiens. 129 samples. Type: Expression profiling by array.
Expression quantitative trait loci (eQTL) analysis of mouse lung tumors
GEO Series GSE71232. Mus musculus. 143 samples. Type: Expression profiling by array.
C57BL/6 substrain differences in inflammatory and neuropathic nociception and genetic mapping of a major quantitative trait locus underlying acute thermal nociception
GEO Series GSE119719. Mus musculus. 115 samples. Type: Expression profiling by high throughput sequencing.
Mapping quantitative trait loci and developing their KASP markers for Pre-harvest Sprouting resistance of Henan wheat varieties in China
GEO Series GSE222342. Triticum aestivum. 27 samples. Type: Expression profiling by high throughput sequencing.
Determinants of gastric cancer immune escape identified from non-coding immune-landscape quantitative trait loci
GEO Series GSE261709. Homo sapiens. 7 samples. Type: Other.
Data from: Sex chromosome linked genetic variance and the evolution of sexual dimorphism of quantitative traits
Theory predicts that sex chromsome linkage should reduce intersexual genetic correlations thereby allowing the evolution of sexual dimorphism. Empirical evidence for sex linkage has come largely from crosses and few studies have examined how sexual dimorphism and sex linkage are related within outbred populations. Here we use data on an array of different traits measured on over 10,000 individuals from two pedigreed populations of birds (collared flycatcher and zebra finch) to estimate the amount of sex linked genetic variance (h2z). Out of 17 traits examined, eight showed a non-zero h2Z estimate but only four were significantly different from zero (wing patch size and tarsus length in collared flycatchers, wing length and beak colour in zebra finches). We further tested how sexual dimorphism and the mode of selection operating on the trait relate to the proportion of sex linked genetic variance. Sexually selected traits did not show higher h2Z than morphological traits and there was only a weak positive relationship between h2Z and sexual dimorphism. However, given the relative scarcity of empirical studies it is premature to make conclusions about the role sex chromosome linkage in the evolution of sexual dimorphism.
Data from: Lineage-specific mapping of quantitative trait loci
We present an approach for quantitative trait locus (QTL) mapping, termed "lineage-specific QTL mapping", for inferring allelic changes of QTL evolution along branches in a phylogeny. We describe and analyze the simplest case: by adding a third taxon into the normal procedure of QTL mapping between pairs of taxa, such inferences can be made along lineages to a presumed common ancestor. While comparisons of QTL maps among species can identify homology of QTLs by apparent co-location, lineage specific mapping of QTL can classify homology into (1) orthology (shared origin of QTL) versus (2) paralogy (independent origin of QTL within resolution of map distance). In this light, we present a graphical method that identifies six modes of QTL evolution in a three taxon comparison. We then apply our model to map lineage-specific QTLs for inbreeding among three taxa of yellow monkeyflower: Mimulus guttatus and two inbreeders M. platycalyx and M. micranthus, but critically assuming outcrossing was the ancestral state. The two most common modes of homology across traits were orthologous (shared ancestry of mutation for QTL alleles). The outbreeder M. guttatus had the fewest lineage- specific QTL, in accordance with the presumed ancestry of outbreeding. Extensions of lineage-specific QTL mapping to other types of data and crosses, and to inference of ancestral QTL state, are discussed.
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.