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1,813 results for “outcome study”
Characteristics and outcomes of fetuses with laterality defects are the current outcomes better? A single center study
<p>Dataset from Fesslova V, Pluchinotta F, Brankovic J, Boschetto C, Piazza L, Inversetti A, Sigismondi C, Giorgione V, Frigiola A. Characteristics and outcomes of fetuses with laterality defects are the current outcomes better? A single center study. J Matern Fetal Neonatal Med. 2021 Feb;34(4):547-554. doi: 10.1080/14767058.2019.1610737. Epub 2019 May 20. PMID: 31106637.</p> <p>Abstract</p> <p><strong>Objective<em>:</em></strong> To analyze the more recent outcomes of fetuses with different laterality defects.<strong>Material and methods:</strong> Out of 1508 fetuses with congenital heart disease (CHD) diagnosed by echocardiography between January 1995 and December 2015, 94 (6.3%) presented abnormal visceroatrial situs: 42 till December 2002 (group 1, analyzed retrospectively) and 52 since then until December 2015 (group 2, analyzed prospectively). Twenty-one had left isomerism (Lisom), 22 right isomerism (Risom), 16 situs inversus- dextrocardia (SVI-dx), 5 situs inversus- levocardia (SVI-levo), and 30 situs solitus-dextrocardia (SSol-dx).<strong>Results:</strong> Seventy-six cases (81%) had CHD, more frequently complex atrioventricular defect. Eighteen cases showed normal heart: half of subgroups SVI-dx and SVI-levo, a third of SSol-dx. Postoperative mortality in continuing pregnancy in group 2 was 43.7 versus 40% in group 1, lower in SVs-dx (0 versus 50%) and Lisom (33.3 versus 66.7%), worse in Risom (71.4 versus 25%). Total mortality in group 2 was 48.3 versus 55% in group 1, better in Ssol-dx (37.5 versus 50%) and in Lisom (27.4 versus 71.4%). In isolated forms all but one case are alive.<strong>Conclusions:</strong> Our fetal cases presented a relevant mortality in both periods. The outcomes were slightly better in a more recent era in SSol and Lisom.What is known about this topic?Out of laterality defects, the heterotaxies (i.e. left and right isomerism) are known to be associated to a relevant mortality in fetal and neonatal cases.Heterotaxies have a variable position of the heart, but some authors evaluated only those with dextrocardia in their studies on different laterality defects.Controversial data are presented in the literature for the outcomes of fetuses with laterality defects. Many large studies analyzed the data of a very long time period in which it is opinable to compare the results of the treatment, because of a recent improved management and surgical techniques.What does this study add?Our study presents an experience of a single center with cases of different types of laterality defects observed during a routine fetal echocardiography, not only heterotaxies.The knowledge of different laterality defects and of their characteristics (association with cardiac and extracardiac anomalies or with normal heart) is useful for the prenatal counseling.We compare the postoperative and total mortality in more recent period (since 2003) with respect to the previous era (1995-2002).</p>
Dataset related to article "Sport Activity and Clinical Outcomes after Hip Arthroscopy with Acetabular Microfractures at a Minimum 2-Year Follow-Up: A Matched-Pair Controlled Study".
<p> This record contains raw data related to article “</p> <p>Sport Activity and Clinical Outcomes after Hip Arthroscopy with Acetabular Microfractures at a Minimum 2-Year Follow-Up: A Matched-Pair Controlled Study"</p> <p>Abstract: Background: Acetabular microfractures for cartilage lesions have been shown to be a safe procedure able to improve patient reported outcomes (PROs). Nevertheless, the return to sport activity rate represents a crucial outcome to be investigated in these young athletic patients. Methods: Patients undergoing acetabular microfracture for full chondral acetabular lesions were compared to a 1:1 matched-pair by age and gender control group undergoing hip arthroscopy without microfractures. Clinical assessment was performed with PROs and participation in sports in terms of type and level of activities was evaluated preoperatively and at 2-years follow-up. Results: A total of 62 patients with an average age of 35.1 ± 8.1 (microfracture group) and 36.4 ± 6.3 (control group) were included. In both groups, the average values of PROs significantly increased from preoperatively to the last follow-up. There was no significant difference between the two groups in the number of patients playing at the amateur and elite level preoperatively and at the last follow-up. Conclusions: Microfractures for the management of full-thickness acetabular chondral defect provides good clinical results at a minimum follow-up of two years, which are not inferior to a matched-pair control group. Patients undergoing this procedure are likely able to return at the same level of sport before surgery.</p> <p> </p>
Longitudinal bibliometric investigation of trending orthodontic research topics, study designs and outcomes: are we reporting patient-focused outcomes?
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Forest plots of pairwise comparisons for Primary Outcomes (limited to studies with low ROB only)
Open the record for dataset details and reuse information.
The Italian midwifery core outcome set (M-COS) for healthy childbearing women and newborns: Development and initial validation study
<p>Maga G, Brigante L, Del Bo E, Cappadona R, Daniele MAS, Arrigoni C, Caruso R, Magon A. The Italian midwifery core outcome set (M-COS) for healthy childbearing women and newborns: Development and initial validation study. Midwifery. 2022 May;108:103292. doi: 10.1016/j.midw.2022.103292. Epub 2022 Feb 23. PMID: 35235891.</p> <p><strong>Abstract</strong></p> <p><strong>Objective: </strong>This study aimed to develop and validate a midwifery core outcome set (M-COS) for Italian settings based on a salutogenic framework of maternity care.</p> <p><strong>Design: </strong>A multi-phase and multi-method study was performed. In phase one, we conducted a literature review to identify a preliminary set of outcomes sensitive to midwifery care. In phase two, the qualitative and quantitative content validity of the M-COS was tested. Finally, in the third phase, construct validity was explored through a cross-sectional study to assess the psychometric properties of the M-COS through exploratory and confirmative factor analysis. This study was conducted from December 2019 to April 2020 in Italy.</p> <p><strong>Participants: </strong>Three main groups of experts/midwives were involved. Group One (n = 10) was involved in the content validity phase, while the other two groups (Group Two and Group Three) were involved in the construct validity phase (n = 300).</p> <p><strong>Results: </strong>The M-COS includes six outcome domains and thirty-one core outcomes perceived as sensitive to midwifery care, namely: mortality and morbidity (n = 6 outcomes), childbirth (n = 3), postnatal period (n = 6), maternal health (n = 11), maternal-infant bonding (n = 3), and maternal self-care (n = 2). All domains showed good evidence of internal consistency.</p> <p><strong>Conclusion: </strong>The Italian M-COS is a novel tool that will facilitate the consistent measurement of core outcomes sensitive to midwifery care from the antenatal to the postnatal period in Italian settings. This initial work will be followed by further studies, including validation by service users.</p> <p><strong>Implications for practice: </strong>The use of the M-COS in clinical practice would facilitate evidence-based data collection and thus contribute to promoting high-quality maternity care.</p>
Dataset related to article "Clinical and radiological outcomes of an uncemented metaphyseal short stem at minimum 10 years of follow‑up: a prospective observational study".
<p>This record contains raw data related to article "Clinical and radiological outcomes of an uncemented metaphyseal short stem at minimum 10 years of follow‑up: a prospective observational study"</p> <p>Abstract</p> <p><strong>Purpose: </strong>There is growing interest around short stems as they provide a less invasive approach for total hip arthroplasty preserving bone stock for a possible revision surgery if required. The main purpose of this work was to assess the long-term performance of an uncemented metaphyseal short stem in terms of survival rate and in addition its clinical and radiological outcomes.</p> <p><strong>Materials and methods: </strong>From January to December 2010, we prospectively enrolled all consecutive patients undergoing primary total hip arthroplasty with an uncemented metaphyseal short stem in our institution with a minimum follow-up of 10 years. The radiographic features investigated were the varus-valgus stem orientation, areas of osteolysis and radiolucencies, stress shielding, and heterotopic calcifications. The clinical outcomes were measured using the HHS.</p> <p><strong>Results: </strong>A total of 163 patients (172 hips) were finally included and the measured survival rate at 10 years was 99.6%. The average HHS increased from 55.0 preoperatively to 97.8 at the last follow-up (p < 0.0001). Among them, 137 patients (164 hips) were also available for radiographic assessment. Mild varus malalignment was observed in 40% of cases and remained stable in the serial X-rays and was not associated with step loosening. Mild stress shielding was observed around 13 stems (9%) and moderate only around 3 implants.</p> <p><strong>Conclusion: </strong>In conclusion, the uncemented metaphyseal short stems showed excellent survival and clinical results at 10 years and at a radiographical level very low stress shielding was observed; moreover, besides the high frequency of varus alignment the implanted stems was not associated with revision surgery or with worse clinical outcomes.</p> <p><strong>Keywords: </strong>Long-term; Outcomes; Short stem; THA.</p>
Dataset related to article "Clinical Outcomes and Complication Rate after Single-Stage Hardware Removal and Total Hip Arthroplasty: A Matched-Pair Controlled Study"
<p>This record contains raw data related to article "Clinical Outcomes and Complication Rate after Single-Stage Hardware Removal and Total Hip Arthroplasty: A Matched-Pair Controlled Study"</p> <p>Abstract: Background: Single-stage hardware removal and total hip arthroplasty is a complex surgical procedure, comparable to revision surgery. The purpose of the current study is to evaluate singlestage hardware removal and THA outcomes, compare this technique with a matched control group that has undergone primary THA and assess the risk of periprosthetic joint infection with a 24-month minimum follow-up. Methods: This study included all those cases treated with THA and concomitant hardware removal from 2008 to 2018. The control group was selected on a 1:1 ratio among patients who underwent THA for primary OA. The Harris Hip (HHS) and University of California at Los Angeles Activity (UCLA) scores, infection rate and early and delayed surgical complications were recorded. Results: One hundred and twenty-three consecutive patients (127 hips) were included, and the same number of patients was assigned to the control group. The final functional scores were comparable between the two groups; a longer operative time and transfusion rate were recorded in the study group. Finally, an increased incidence of overall complications was reported (13.8% versus 2.4%), but no cases of early or delayed infection were found. Conclusions: Single-stage hardware removal and THA is a safe and effective but technically demanding technique, with a higher incidence of overall complications, making it more similar to revision THA than to primary THA. Keywords: conversion THA; hardware removal; periprosthetic joint disease; one-stage.</p>
Occlusal outcome of orthodontic treatment with pre-adjusted straight-wire and standard Edgewise appliances: a retrospective cohort study
<p>Dataset for all analyses</p>
Severe acquired brain injury aetiologies, early clinical factors, and rehabilitation outcomes: a retrospective study on pediatric patients in rehabilitation.
<p>Raw data. Contains clinical and demographic data of 500+ pediatric patients in rehabilitation, analyzed in the article.</p>
Environmental Exposures, Characteristics, and Treatment Outcomes of Hypersensitivity Pneumonitis at a Rural Appalachian Academic Medical Center: A Cross-sectional Study
<p>Data set for our research project titled above.</p>
Montessori primary schools' effectiveness: a quasi-experimental study on schooling outcomes
<p>Montessori education advocates individualized student development, moving away from standardized schooling outcomes. This study investigates whether a group of Montessori students (experimental groups) exhibit more diverse learning achievements compared to a control group of non-Montessori students, matched through the simple matching method (Bailey, 2007), to control for background variables. Employing a quasi-experimental design, the hypothesis tested was that the experimental groups (N = 535-710) would display a significantly higher standard deviation in standardized measures of schooling outcomes in mathematics and language. The study encompassed 2nd, 5th, 8th, and 10th grade students across two separate cohorts. Results indicate that, depending on grade and cohort, Montessori students attain either comparable or significantly higher scores than non-Montessori students, with greater score variability observed, particularly in mathematics. This finding implies the necessity for future investigations into Montessori teachers' instructional practices in mathematics and language.</p>
Dentogingival aesthetic outcomes following orthodontic treatment with fixed appliances: a clinical cohort study
<p>Dataset for all analyses of the study</p>
Feasibility Study to Assess Outcomes of Immediately Inserted and Restored Dental Implants Using pH-modified Tetranite
ClinicalTrials.gov study NCT05535426. IPD Sharing: NO. Countries: 1. Publications: 1.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
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DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.