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5,805 results for “Data model”
single-cell RNAseq data (data set 12) in the publication scFASTCORMICS: A contextualization algorithm to reconstruct metabolic multi-cell population models from single-cell RNAseq data
<p>The present dataset (dataset12) was used as input to build scFASTCORMICS models. The files correspond to the clusters identified by Seurat in the single-cell data from pancreas donor10 downloaded from the GEO website (<strong>GSE114297). </strong></p> <p> </p> <p>see the protocol: scFASTCORMICS: A contextualization algorithm to reconstruct metabolic multi-cell population models from single-cell RNAseq data</p> <p>and github: https://github.com/sysbiolux/scFASTCORMICS</p> <p>For more information, version updates of the scFASTCORMICS. </p>
single-cell RNAseq data (data set 16) in the publication scFASTCORMICS: A contextualization algorithm to reconstruct metabolic multi-cell population models from single-cell RNAseq data
<p>The present dataset (dataset16) was used as input to build scFASTCORMICS models. The files correspond to the clusters identified by Seurat in the single-cell data from CD4 T-cells in PACA samples downloaded from the GEO website (GSE156728)<strong>. </strong></p> <p>see the protocol: scFASTCORMICS: A contextualization algorithm to reconstruct metabolic multi-cell population models from single-cell RNAseq data</p> <p>and github: https://github.com/sysbiolux/scFASTCORMICS</p> <p>For more information, version updates of the scFASTCORMICS. </p> <p> </p>
single-cell RNAseq data (data set 11) in the publication scFASTCORMICS: A contextualization algorithm to reconstruct metabolic multi-cell population models from single-cell RNAseq data
<p>The present dataset (dataset11) was used as input to build scFASTCORMICS models. The files correspond to the clusters identified by Seurat in the single-cell data from pancreas donor9 downloaded from the GEO website (<strong>GSE114297). </strong></p> <p> </p> <p>see the protocol: scFASTCORMICS: A contextualization algorithm to reconstruct metabolic multi-cell population models from single-cell RNAseq data</p> <p>and github: https://github.com/sysbiolux/scFASTCORMICS</p> <p>For more information, version updates of the scFASTCORMICS. </p>
single-cell RNAseq data (data set 14) in the publication scFASTCORMICS: A contextualization algorithm to reconstruct metabolic multi-cell population models from single-cell RNAseq data
<p>The present dataset (dataset14) was used as input to build scFASTCORMICS models. The files correspond to the clusters identified by Seurat in the single-cell data from pancreas donor12 downloaded from the GEO website (<strong>GSE114297). </strong></p> <p> </p> <p>see the protocol: scFASTCORMICS: A contextualization algorithm to reconstruct metabolic multi-cell population models from single-cell RNAseq data</p> <p>and github: <a href="https://github.com/sysbiolux/scFASTCORMICS">https://github.com/sysbiolux/scFASTCORMICS</a></p> <p>For more information, version updates of the scFASTCORMICS. </p>
single-cell RNAseq data (data set 9) in the publication scFASTCORMICS: A contextualization algorithm to reconstruct metabolic multi-cell population models from single-cell RNAseq data
<p>The present dataset (dataset9) was used as input to build scFASTCORMICS models. The files correspond to the clusters identified by Seurat in the single-cell data from pancreas donor7 downloaded from the GEO website (<strong>GSE114297). </strong></p> <p> </p> <p>see the protocol: scFASTCORMICS: A contextualization algorithm to reconstruct metabolic multi-cell population models from single-cell RNAseq data</p> <p>and github: <a href="https://github.com/sysbiolux/scFASTCORMICS">https://github.com/sysbiolux/scFASTCORMICS</a></p> <p>For more information, version updates of the scFASTCORMICS. </p>
single-cell RNAseq data (data set 8) in the publication scFASTCORMICS: A contextualization algorithm to reconstruct metabolic multi-cell population models from single-cell RNAseq data
<p>The present dataset (dataset8) was used as input to build scFASTCORMICS models. The files correspond to the clusters identified by Seurat in the single-cell data from pancreas donor6 downloaded from the GEO website (<strong>GSE114297). </strong></p> <p> </p> <p>see the protocol: scFASTCORMICS: A contextualization algorithm to reconstruct metabolic multi-cell population models from single-cell RNAseq data</p> <p>and github: <a href="https://github.com/sysbiolux/scFASTCORMICS">https://github.com/sysbiolux/scFASTCORMICS</a></p> <p>For more information, version updates of the scFASTCORMICS. </p>
single-cell RNAseq data (data set 7) in the publication scFASTCORMICS: A contextualization algorithm to reconstruct metabolic multi-cell population models from single-cell RNAseq data
<p>The present dataset (dataset7) was used as input to build scFASTCORMICS models. The files correspond to the clusters identified by Seurat in the single-cell data from pancreas donor5 downloaded from the GEO website (<strong>GSE114297). </strong></p> <p> </p> <p>see the protocol: scFASTCORMICS: A contextualization algorithm to reconstruct metabolic multi-cell population models from single-cell RNAseq data</p> <p>and github: <a href="https://github.com/sysbiolux/scFASTCORMICS">https://github.com/sysbiolux/scFASTCORMICS</a></p> <p>For more information, version updates of the scFASTCORMICS. </p>
single-cell RNAseq data (data set 19) in the publication scFASTCORMICS: A contextualization algorithm to reconstruct metabolic multi-cell population models from single-cell RNAseq data
<p>The present dataset (dataset19) was used as input to build scFASTCORMICS models. The files correspond to the clusters identified by Seurat in the single-cell data from Liver cancer set 2 samples downloaded from the GEO website (GSE125449)<strong>. </strong></p> <p> </p> <p>see the protocol: scFASTCORMICS: A contextualization algorithm to reconstruct metabolic multi-cell population models from single-cell RNAseq data</p> <p>and github: <a href="https://github.com/sysbiolux/scFASTCORMICS">https://github.com/sysbiolux/scFASTCORMICS</a></p> <p>For more information, version updates of the scFASTCORMICS. </p>
Discretized bulk data by the discretization step of rFASTCORMICS used in in the publication scFASTCORMICS: A contextualization algorithm to reconstruct metabolic multi-cell population models from single-cell RNAseq data
<p>Bulk data RNAseq data were downloaded from GEO, GTEX, and other sources (see below) and discretized by the discretization step of rFASTCORMICS (Pacheco et al, 2019) used in the optimization step in scFASTCORMICS:</p> <p>CRC bulk RNAseq data were obtained from Lee et al(2020) <br> CRC control (NM) was downloaded from GSE81861 (GTEX, Healthy colon from)</p> <p>Pancreatic Human islet bulk RNAseq data was downloaded from EBI Expression Atlas (Pancreatic islet cells)</p> <p>Immune cells in pancreatic carcinoma bulk data were obtained from GEO (GSE156278)</p> <p>liver and breast cancer bulk RNAseq data were obtained from the TCGA (GSE62944)</p> <p> </p> <p>rFASTCORMICS and tutorial on rFASTCORMICS can be found: https://github.com/sysbiolux</p> <p> </p> <p> </p> <p> </p> <p><br> </p>
single-cell RNAseq data (data set 5) in the publication scFASTCORMICS: A contextualization algorithm to reconstruct metabolic multi-cell population models from single-cell RNAseq data
<p>The present dataset (dataset5) was used as input to build scFASTCORMICS models. The files correspond to the clusters identified by Seurat in the single-cell data from pancreas donor3 downloaded from the GEO website (<strong>GSE114297). </strong></p> <p>see the protocol: scFASTCORMICS: A contextualization algorithm to reconstruct metabolic multi-cell population models from single-cell RNAseq data</p> <p>and github: https://github.com/sysbiolux/scFASTCORMICS</p> <p>For more information, version updates of the scFASTCORMICS. </p>
single-cell RNAseq data (data set 15) in the publication scFASTCORMICS: A contextualization algorithm to reconstruct metabolic multi-cell population models from single-cell RNAseq data
<p>The present dataset (dataset15) was used as input to build scFASTCORMICS models. The files correspond to the clusters identified by Seurat in the single-cell data from CD8 T-cells in PACA samples downloaded from the GEO website (GSE156728)<strong>. </strong></p> <p>see the protocol: scFASTCORMICS: A contextualization algorithm to reconstruct metabolic multi-cell population models from single-cell RNAseq data</p> <p>and github: https://github.com/sysbiolux/scFASTCORMICS</p> <p>For more information, version updates of the scFASTCORMICS. </p>
single-cell RNAseq data (data set 4) in the publication scFASTCORMICS: A contextualization algorithm to reconstruct metabolic multi-cell population models from single-cell RNAseq data
<p>The present dataset (dataset4) was used as input to build scFASTCORMICS models. The files correspond to the clusters identified by Seurat in the single-cell data from pancreas donor2 downloaded from the GEO website (<strong>GSE114297). </strong></p> <p> </p> <p>see the protocol: scFASTCORMICS: A contextualization algorithm to reconstruct metabolic multi-cell population models from single-cell RNAseq data</p> <p>and github: https://github.com/sysbiolux/scFASTCORMICS</p> <p>For more information, version updates of the scFASTCORMICS. </p>
single-cell RNAseq data (data set 3) in the publication scFASTCORMICS: A contextualization algorithm to reconstruct metabolic multi-cell population models from single-cell RNAseq data
<p>The present dataset (dataset3) was used as input to build scFASTCORMICS models. The files correspond to the clusters identified by Seurat in the single-cell data from normal Pancreas donor1 downloaded from the GEO website (GSE114297)<strong>. </strong></p> <p>see the protocol: scFASTCORMICS: A contextualization algorithm to reconstruct metabolic multi-cell population models from single-cell RNAseq data</p> <p>and github: https://github.com/sysbiolux/scFASTCORMICS</p> <p>For more information, version updates of the scFASTCORMICS. </p> <pre> </pre>
Data for: Using a demographic model to project the long-term effects of fire management on tree biomass in Australian savannas
<p>Tropical savannas are characterised by high primary productivity and high fire frequency, such that much of the carbon captured by vegetation is rapidly returned to the atmosphere. Hence, there have been suggestions that management-driven reductions in savanna fire frequency and/or severity could significantly reduce greenhouse gas emissions and sequester carbon in tree biomass. However, a key knowledge gap is the extent to which savanna tree biomass will respond to modest shifts in fire regimes due to plausible, large-scale management interventions. Here, we: (1) characterise relationships between the frequency and severity of fires and key demographic rates of savanna trees, based on long-term observations in vegetation monitoring plots across northern Australia; (2) use these relationships to develop a process-explicit demographic model describing the effects of fire on savanna tree populations; and (3) use the demographic model to address the question: to what extent is it feasible, through the strategic application of prescribed burning, to increase tree biomass in Australian tropical savannas? Our long-term tree monitoring dataset included observations of 12,344 tagged trees in 236 plots, monitored for between 3 and 24 years. Analysis of this dataset showed that frequent high-severity fires significantly reduced savanna tree recruitment, survival and growth. Our demographic model suggested that: (1) despite the negative effects of frequent high-severity fires on demographic rates, savanna tree biomass appears to be suppressed by only a relatively small amount by contemporary fire regimes, characterised by a mix of low- to high-severity fires; and (2) plausible, management-driven reductions in the frequency of high-severity fires are likely to lead to increases in tree biomass of about 11.0 t DM ha<sup>–1</sup> (95% confidence interval: -1.2–20.8) over a century. Accounting for this increase in carbon storage could generate significant carbon credits, worth on average three times those generated annually by current greenhouse gas (methane and nitrous oxide) abatement projects, and has the potential to significantly increase the economic viability of fire/carbon projects, thereby promoting ecologically sustainable management of tropical savannas in Australia and elsewhere. This growing industry has the potential to bring much-needed economic activity to savanna landscapes, without compromising important natural and cultural values.</p>
A Scalable Data Management System Data Model facilitating the integration of any inspection system and the automated data digitalization process.
<p>In the context of the EU-funded project PILOTING (No. 871542), a scalable Data Management System (DMS) was deployed and facilitated the easy integration of nine different robotic systems and various payloads and the storing of all the data observations produced during the inspections. In particular, a three-phase methodology was adopted for the creation of the DMS Data Model (DMS-DM) in order to define the architectural design of the DMS. <br> The first phase was to semantically define the entities of the PILOTING ecosystem, identifying assets and activities that were important to the data providers, and including them in the data model design. The second phase was to identify relationships between the entities, focusing on information that must pre-exist for entities to be semantically accurate, hierarchies between entities, especially physical assets, and the data needed to form the inspection plan. For the third phase, the information collected by the previous two stages of the data model construction was used to create the overall data model, taking into consideration the possible integration with third parties and the needs of the I&M Visualization portal. <br> The constructed document is attempted to present the designed Entity-Relationship-Diagram (ERD) of the DMS-DM. Additional definitions of the existing entities and the relations between them are also depicted. </p>
Waveform data for centroid moment tensor solutions presented in publication "Bayesian seismic source inversion with a 3-D Earth model of the Japanese islands"
<p>This dataset contains waveform data for centroid moment tensor solutions inferred using Hamiltonian Monte Carlo sampling algorithm and a 3-D Earth model of the Japanese islands. Specifically, it includes processed observed waveforms from the Full Range Seismograph Network of Japan (F-Net, http://www.fnet.bosai.go.jp) and synthetic waveforms for the maximum-likelihood solutions as well as Global Centroid Moment Tensor (GCMT) solutions for all study events inverted at different periods. Detailed description of the dataset is included in the README file. </p>
Saved model and preprocessed data for "CRMnet:a deep learning model for predicting gene expression from large regulatory sequence datasets"
<p>Saved TUNet model and preprocessed training data for "CRMnet: a deep learning model for predicting gene expression from large regulatory sequence datasets"</p> <p>To load the trained model:</p> <pre><code class="language-python">import tensorflow as tf tf.keras.models.load_model("path to the model folder")</code></pre> <p>for more information please find our repository: https://github.com/jiayuwen/CRMnet</p>
Supplemental information and Data for: Colloidal physics modeling reveals how per-ribosome productivity increases with growth rate in E. coli
<p>Faster growing cells must synthesize proteins more quickly. Increased ribosome abundance only partly accounts for increases in total protein synthesis rates. The productivity of individual ribosomes must increase too, almost doubling by an unknown mechanism. Prior models point to diffusive transport as a limiting factor but surface a paradox: faster growing cells are more crowded, yet crowding slows diffusion. We suspected physical crowding, transport, and stoichiometry, considered together, might reveal a more nuanced explanation. To investigate, we built a first-principles physics-based model of <em>E. coli</em> cytoplasm in which Brownian motion and diffusion arise directly from physical interactions between individual molecules of finite size, density, and physiological abundance. Using our microscopically-detailed model, we predict that physical transport of individual ternary complexes accounts for ~80% of translation elongation latency. We also find that volumetric crowding increases at faster growth even as cytoplasmic mass density remains relatively constant. Despite slowed diffusion, we predict that improved proximity between ternary complexes and ribosomes wins out, illustrating a simple physics-based mechanism for how individual elongating ribosomes become more productive. We speculate how crowding imposes a physical limit on growth rate and undergirds cellular behavior more broadly. Unfitted colloidal-scale modeling offers systems biology a complementary "physics engine" for exploring how cellular-scale behaviors arise from physical transport and reactions among individual molecules.</p>
Data for HydrAMP - a deep generative model for antimicrobial peptide discovery
<ul> <li>data- training data for peptides < 25 AA (16.8 MB)</li> <li>models - checkpoints of HydrAMP, PepCVAE, and Basic models for every training epoch (466 MB)</li> <li>results - dumped generation results for every model. Required for running comparison notebooks (832 MB)</li> <li>wheels - custom TensorFlow packages (1 GB)</li> </ul> <p> </p>
Data from: Wallace 2: A shiny app for modeling species niches and distributions redesigned to facilitate expansion via module contributions
<p>These are the occurrence locality datasets used in the example provided in "<em>wallace</em> 2: a <em>shiny</em> app for modeling species niches and distributions redesigned to facilitate expansion via module contributions" published in Ecography (DOI: 10.1111/ecog.06547). The analysis workflow is displayed in the Supporting information of the paper (Fig. S1), and these data are also used in the <em>wallace</em> 2 vignette (<a href="https://wallaceecomod.github.io/wallace/articles/tutorial-v2.html">https://wallaceecomod.github.io/wallace/articles/tutorial-v2.html</a>).</p>
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.