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2,285
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Dataset results
2,285 results for “T-cells”
Cell Specific Expression & Pathway Analyses Reveal Novel Alterations in Trauma-Related Human T-Cell & Monocyte Pathways
GEO Series GSE5580. Homo sapiens. 42 samples. Type: Expression profiling by array.
Chromatin accessibility governs the differential response of cancer and T-cells to arginine starvation
GEO Series GSE137034. Homo sapiens. 78 samples. Type: Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by array.
DNA methylation regulates the neonatal CD4+ T-cell response to pneumonia in mice
GEO Series GSE106806. Mus musculus. 12 samples. Type: Methylation profiling by high throughput sequencing.
Regorafenib combined with PD1 blockade increases CD8 T-cell infiltration by inducing CXCL10 expression in hepatocellular carcinoma
GEO Series GSE301139. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.
The Genomic Complexity of Early T-Cell Progenitor Acute Lymphoblastic Leukemia
Early T-cell precursor acute lymphoblastic leukemia (ETP ALL) is an aggressive malignancy of unknown genetic basis. We performed whole-genome sequencing of 12 ETP ALL cases and assessed the frequency of the identified somatic mutations in 94 T-cell acute lymphoblastic leukemia cases. ETP ALL was characterized by activating mutations in genes regulating cytokine receptor and RAS signaling, inactivating lesions disrupting hematopoietic development, and histone-modifying genes. We also identified new targets of recurrent mutation including DNM2, ECT2L and RELN. The mutational spectrum is similar to myeloid tumors, and moreover, the global transcriptional profile of ETP ALL was similar to that of normal and myeloid leukemia hematopoietic stem cells. These findings suggest that addition of myeloid-directed therapies might improve the poor outcome of ETP ALL.
Interleukin-32 is progressively expressed in Mycosis Fungoides independent of helper T-cell 2 and helper T-cell 9 polarization
GEO Series GSE58033. Homo sapiens. 4 samples. Type: Expression profiling by array.
Expression data from mouse CD3+ T-cells from WT and KLF13 KO mice
GEO Series GSE50617. Mus musculus. 10 samples. Type: Expression profiling by array.
Therapeutic Potential of NRF2 activating drug RTA-408 in suppressing T-cell effector responses and inflammatory bowel disease
GEO Series GSE277154. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Ant-leukemic effect of CDK9 inhibition in T-cell prolymphocytic leukemia (mRNA)
GEO Series GSE155747. Homo sapiens. 6 samples. Type: Expression profiling by array.
Activation of the LMO2 oncogene through a somatically acquired neomorphic promoter in T-Cell Acute Lymphoblastic Leukemia
GEO Series GSE94000. Homo sapiens. 5 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Tumour immune contexture is a determinant of anti-CD19 CAR T-cell efficacy in large B cell lymphoma
GEO Series GSE197977. Homo sapiens. 74 samples. Type: Expression profiling by array.
CDK9 is a Dependency in GATA-3 driven and MCL-1 independent T-cell Lymphomas [ChIP-seq]
GEO Series GSE296537. Homo sapiens. 33 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
DJ-1 depletion prevents immunoaging in T-cell compartments
GEO Series GSE173904. Mus musculus. 6 samples. Type: Expression profiling by array.
Foxp3-specific deletion of CREB generates Th2 biased ST-2 positive regulatory T-cells with enhanced IL-10 production and suppressive capacity
GEO Series GSE157693. Mus musculus. 6 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Global expression of noncoding RNome reveals dysregulation of small RNAs in patients with HTLV-1–associated adult T-cell leukemia: a pilot study
<p>Small RNAs expressions in patients with HTLV-1–associated adult T-cell leukemia</p>
pT1 Hotspot Tumor Budding T-cell Graph (pT1-HBTG) Dataset
<p>Dataset described in MIDL 2023 publication <a href="https://openreview.net/forum?id=ruaXPgZCk6i">"Tumor Budding T-cell Graphs: Assessing the Need for Resection in pT1 Colorectal Cancer Patients"</a>. For more information, please refer to the article. <strong>Please cite this article when using the data set.</strong></p> <p>The code for the Graph Neural Network experiments can be found on GitHub: <a href="https://github.com/digitalpathologybern/pT1-HBTG-MIDL2023">https://github.com/digitalpathologybern/pT1-HBTG-MIDL2023</a>.</p> <p><strong>Content:</strong></p> <ul> <li><strong>Zip file containing the different graph configurations in <a href="https://www.wikiwand.com/en/GXL">GXL format</a>.</strong> <ul> <li>Node labels: <ul> <li>Coordinates x and y in <span>\(\mu m\)</span> relative to the top-left of the hotspot (0/0).</li> <li>Type: lymphocyte/tumor bud (based on automated detection)</li> <li>ImageNet ViT-26 (DINO) features</li> </ul> </li> <li>Edge labels: <ul> <li>Distance between the nodes in <span>\(\mu m\)</span></li> </ul> </li> <li><br> </li> </ul> </li> <li><strong>JSON file with the class labels and cross-validation splits.</strong> The first level contains the split (5-folds, index 0-4), the second level the class labels (0/1), and the list of corresponding file-IDs. <pre><code>{ "0": { "0": [ "107_1", "107_2", ... ], "1": [ "160", "178_1", "178_2", ... ] }, ... "4": { "0": [ "10", "103", "104", ... ], "1": [ "117", "140_1", "140_2", ... ] } }</code></pre> <p> </p> </li> <li><strong>Zip file containing the PNGs of the ITBCC hotspots</strong> on which the graphs are based, extracted at full resolution (level 0, area of 0.785 mm<sup>2</sup>). The WSIs were digitized using a Pannoramic 250 scanner at <span>\(0.243\mu m/pixel\)</span>.</li> <li> </li> <li><strong>Zip file containing the patches</strong> from which the ImageNet-based features were extracted (size 200x200 pixels, centered on the coordinates of the element)</li> </ul> <p><strong>File-ID nomenclature</strong><br> The first number indicates the patient/case (e.g. 10.gxl). If we have more than one WSI per patient, they are indicated by a second number (e.g. 13_1.gxl and 13_2.gxl). The file-ID is consistent between all data.</p> <p><strong>Bibtex for citation:</strong></p> <pre><code>@inproceedings{studer2023tumor, title={Tumor Budding T-cell Graphs: Assessing the Need for Resection in pT1 Colorectal Cancer Patients}, author={Studer, Linda and Bokhorst, John-Melle and Nagtegaal, Iris and Zlobec, Inti and Dawson, Heather and Fischer, Andreas}, booktitle={Medical Imaging with Deep Learning}, year={2023} }</code></pre>
Biomarker Study in Bone Marrow Samples From Patients With T-Cell Acute Lymphoblastic Leukemia
ClinicalTrials.gov study NCT01295476. IPD Sharing: Not stated. Countries: 0. Publications: 0.
Vorinostat and Combination Chemotherapy Before Donor Stem Cell Transplantation for the Treatment of Relapsed Aggressive B-cell or T-cell Non-Hodgkin Lymphoma
ClinicalTrials.gov study NCT04220008. IPD Sharing: Not stated. Countries: 0. Publications: 0.
Expanded Access to T-cell Depleted Haplo-Identical Stem Cells for Patients Receiving Haplo-Identical and Unrelated Cord Blood Transplants
ClinicalTrials.gov study NCT01881334. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Biomarkers in Tumor Tissue Samples From Patients With Peripheral T-cell Lymphoma or Natural Killer Cell Neoplasms
ClinicalTrials.gov study NCT01390597. IPD Sharing: Not stated. Countries: 0. Publications: 0.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.